Health
72nd Graduation: Doctoral Citations – CHS
Published
3 years agoon


AGABA Bekiita Bosco
Molecular Epidemiological Surveillance of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda
Mr. AGABA Bekiita Bosco investigated the biological and molecular changes in malaria parasites that make them difficult to be detected in malaria infected individuals. Once these parasites evade detection, individuals remain untreated leading to severe disease and risk of mortality. The results provide the first large-scale evidence reporting the presence of pfhrp2/3 gene deletions in P. falciparum parasites in Uganda and demonstrated that gene deletions are not confined but rather spread across regions. Further, the study showed that these parasites emerge independently and sponteneously. The findings inform national guidelines for malaria case management and policy for the introduction and deployment of new malaria diagnotic tests. The study was funded by the NIH-Fogarty Malaria training grant and the WHO collaborating center in Australia. The work was supervised by Prof. Moses R. Kamya, Prof. Chae Seung Lim, Dr. Adoke Yeka and Dr. Samuel Nsobya.

AMONGIN Dinah
Understanding Trends and Trajectories of Repeat Adolescent Birth in Uganda
Ms. AMONGIN Dinah studied the magnitude and explanation for repeat adolescent birth (i.e. a second or higher order live birth before age 20 years, following a first birth before age 18 years) and its later life consequences in Uganda. Her results revealed high repeat adolescent births (over 1 in 2) with slight decline in the 30 years of observation (1988/89-2016) although more women over the years wanted to have this repeat birth later. Results suggest life-long negative socio-economic and reproductive health outcomes among women with repeat adolescent births compared to those without. Further, escalation of the socio-economic distress following first birth, domestic violence, and partner coercion, predisposed adolescent girls to sexual exploitation and unwanted marriages. Interventions should focus on preventing repeat adolescent pregnancy and increasing opportunities for adolescent mothers, with a primary focus on: improving school retention/continuation, strengthening family planning services, and preventing early marriage. This study was funded by Training Health Researchers into Vocational Excellence (THRiVE-2) and was supervised by Assoc. Prof Annettee Nakimuli, Assoc. Prof Lenka Benova, Assoc. Prof Lynn Atuyambe, and Assoc. Prof Claudia Hanson.

KAPAATA ANDAMA Anne
Genotypic And Phenotypic Characterization Of Hiv-1 Transmitted/Founder Viruses And Their Effect On Cytokine Profiles And Disease Progression Among Acutely Infected Ugandans
Ms. KAPAATA ANDAMA Anne looked at Genotypic and Phenotypic Characterization of HIV-1 transmitted/founder viruses and their effect on cytokine profiles and disease progression among acutely infected Ugandans. Subtype analysis of inferred transmitted/founder viruses showed a high transmission rate of inter-subtype recombinants (69%) involving mainly A1/D, while pure subtype D variants accounted for one- third of infections (31%). The signal peptide-C1 region and gp41 transmembrane domain were hotspots for A1/D recombination events. She documented diversity in the functional protein domains across the Gag-Pol region of the HIV virus and identified differences in the Gag-p6 domain that were frequently associated with higher in vitro replication. She also found that HIV-1 subtype D infections had higher concentrations of different cytokines than subtype Ainfections. cytokines IL-12/23p40 and IL-1α were associated with faster CD4+T cell count decline while basic fibroblast growth factor was associated with maintenance of CD4+T cell count above 350cells/microliter. This work was funded by the International AIDS Vaccine initiative and supervised by Prof. Pontiano Kaleebu, Eric Hunter and Moses Joloba and Dr Jesus Salazar Gonzalez.

BAKESIIMA Ritah
Modern contraceptive use among female refugee adolescents in northern Uganda: prevalence, effect of peer counselling, adherence and experiences
Ms. BAKESIIMA Ritah studied modern contraceptive use among female refugee adolescents northern Uganda: the prevalence, effect of peer counselling, adherence, and experiences. She found that the use of modern contraceptives among sexually active adolescents was very low with less than 10% using a method, and yet they wanted to delay child birth. This highlights a high unmet need of contraceptives in this population. She also found that peer counselling had a positive effect on acceptance of modern contraceptives; participants who received peer counselling were more likely to accept a contraceptive method compared to those who received routine counselling. The commonest reasons for non-acceptance of a method were partner prohibition and fear of side effects. She recommends that refugee adolescents, together with their partners, are further sensitized of the dangers of teenage pregnancy, and the benefits of contraception in preventing teenage pregnancy and associated complications. This research was funded by SIDA and supervised by Assoc. Prof Elin Larsson, Dr. Jolly Beyeza-Kashesya, Prof. Kristina Gemzell-Danielsson, Dr. Amanda Cleeve, and Dr. Rose Chalo Nabirye.

BAYIGGA Lois
Role of Vaginal Microbiome in Host Susceptibility of HIV Infection in Pregnant Ugandan Women: Inflammatory Response and Epithelial Barrier Integrity
Mr. BAYIGGA Lois investigated the virginal microbial diversity and its immune-modulatory effects on host susceptibility to HIV among pregnant women in Uganda. In the results, the vaginal microbiome of pregnant women in the cross-sectional study was categorised into four distinct cervicotypes. In conclusion, African women had a more diverse vaginal microbiome relative to women in the America and Europe as observed in the literature. This work was supervised by Prof. Damalie Nakanjako, Dr. David Patrict Kateete, Dr. Musa Sekikubo and Prof. Deborah Anderson.

MIJUMBI Deve Rhona
Rapid Response Services to Support Policymaking in Uganda
Ms. MIJUMBI Deve Rhona evaluated the rapid response mechanisms aimed at providing evidence for policymaking in Uganda, including their feasibility and establishment, their uptake amongst the users along with these users’ experiences with them. She was able to determine and confirm the feasibility of an RRS in Uganda and map the establishment, growth, and evolution of the service. She was also able to document the important factors that led to the establishment of the service, then used this information to develop a theoretical framework combining the structural and temporal components of the development of an RRS and the factors important at each stage. She also established the important factors that influence the uptake of the RRS amongst its actual and potential users and also explored the users’ experience with the rapid response (RR) briefs produced by the RRS and used her findings to improve these briefs. The findings from this work are important to enable the use of evidence for decision-making at different levels of governance globally, especially in complex situations where time is barred. The work was funded by the International Development Research Center’s International Research Chairs Initiative and supervised by Prof. Nelson Sewankambo, Prof. John Lavis, and Dr. Andrew Oxman.

MUKURU Moses
An analysis of evolutions in maternal health policies and implementation adaptations in Uganda during the MDG period (2000-2015)
Mr. MUKURU Moses analysed Uganda’s maternal health policies introduced during the fifteen years of the Millennium Development Goals (MDG period) to understand policy failure. This followed the persistence of high preventable maternal mortality, which closed at a Maternal Mortality Ratio (MMR) of 368 deaths per 100,000 live births in 2015 below the target of 131 deaths per 100,000 live births. While most studies explain the failure to achieve maternal health policy targets from epidemiological, interventional and health systems perspectives, this study examined how elite interests underpinning maternal health policies, policy design and implementation influenced maternal health policy failure in Uganda. The study found that the failure to achieve policy targets and persistence of high maternal mortality despite introducing fourteen policy shifts emanated from a complex interplay of factors at the policy formulation, design and implementation levels. Policy elites developed policies which mainly served their selfish political and economic interests while paying limited attention to the goal of reducing maternal mortality. The policy instruments introduced were incoherent, inconsistent and incomprehensive to cover all the causes of maternal mortality rendering the policies ineffective in design. Consequently, maternal health policies could not be fully operationalised at the frontline to support timely response to all the emergencies that cause maternal death. The study was funded by DAAD, the Alliance for Health Policy and Systems Research, Switzerland, through the University of Cape Town, South Africa, the “Support Policy Engagements for Evidence informed (SPEED)” and was supervised by Professor Freddie Ssengooba and Dr Suzanne Kiwanuka.

MUSABA Milton
Obstructed labour in Eastern Uganda: risk factors, electrolyte derangements, and effect of bicarbonate on obstetric outcomes
Dr. MUSABA Milton studied the risk factors, electrolyte derangements, and effect of bicarbonate on obstetric outcomes among women with Obstructed labour (OL). Failure of a woman to give birth normally is called OL. It is often associated with poor outcomes for both the mother and baby, if the intervention (surgical) is not timely. In Uganda, one in five maternal deaths and two in five perinatal deaths are attributed to OL. The risk factors were being a first-time mother, using herbal medicines, and being referred in labour. While being married, having a delivery plan, and an educated partner were protective. Perioperatively, multiple electrolyte derangements were common. Perinatal death was four times higher than the national average, and the predictors were being referred and having a high maternal blood lactate level. Sodium bicarbonate infusion had no significant beneficial or harmful effect. Developing birth and complication readiness plans may help to minimize delays and multiple referrals in case of an emergency. To minimize the effects of metabolic and electrolyte derangements in OL, healthcare providers need to ensure that these patients are well rehydrated especially during transfer to a higher facility. This study was funded by NORHED/NORAD and was supervised by Prof. Grace Ndeezi, Prof. Julius N. Wandabwa, Dr. Justus K. Barageine, and Prof. Andrew D. Weeks

NAMAZZI Gertrude
Burden and risk factors for child developmental disability among infants in Busoga region, in Uganda
Dr. NAMAZZI Gertrude investigated the burden and risk factors for child developmental disability among infants in Busoga region, in Uganda. The study revealed a high burden of child developmental disability at population level and among preterm babies. The caretakers of children with developmental disability expressed emotional stress and an impoverishing experience with limited support from the community and the health system. The key risk factors included: birth asphyxia, malnutrition, newborn infections, and a mother having more than three children. The study findings indicate the need to improve the quality of care during delivery and the postnatal period to prevent birth asphyxia, neonatal infections and malnutrition so as to curb the burden of child developmental disability. In addition, parents should limit the number of children to those they are able to nurture and care for adequately. The study recommends to government to improve the health facility readiness to respond to caretakers’ needs and the needs of children with developmental disability so as to empower families, while respecting their beliefs, to cope with adversity. The study was funded by SIDA and was supervised by Prof. James Tumwine, Assoc. Prof. Peter Waiswa and Assoc. Prof. Helena.

NANKYA Mutyoba Eron Joan
Hepatitis B. Among Ugandan pregnant women: Studies on Epidemiology, knowledge, perceptions and behavioural intentions
Ms. NANKYA Mutyoba Eron Joan investigated the epidemiology, knowledge, perceptions and behavioural intentions associated with Hepatitis B among Ugandan pregnant women. The study was conducted among pregnant women attending routine Antenatal Care in public health facilities in Kampala, Wakiso and Arua Districts. In the results, the overall prevalence of Hepatitis B. Virus infection was 6.1%. Pregnant women in Uganda have a high burden of the virus with significant regional differences, low knowledge and inaccurate perceptions of the virus. This study was funded by SIDA and was supervised by Assoc Prof. Ponsiano Ocama, Asoc Prof. Fredrick Makumbi and Assoc Prof. Lynn Atuyambe.

ODEI OBENG-AMOAKO Gloria Adobea
Retrospective analysis of concurrently wasted and stunted children 6-59 months in the outpatient therapeutic feeding programme in Karamoja: burden, characteristics, detection, response to treatment and outcomes
Ms. ODEI Obeng-Amoako Gloria Adobea examined the burden, characteristics and detection of concurrently wasted and stunted among children under 5 years, and their response to treatment and outcomes in the outpatient therapeutic feeding programme in Karamoja. She found that 5% of children under-5 years in Karamoja were wasted and stunted concurrently. Concurrent wasting and stunting was common among children younger than 3 years and particularly males. She identified optimal weight for age z-score (WAZ) and mid upper arm circumference (MUAC) thresholds for detecting children with concurrent wasting and stunting. Nearly half (49%) of children with severe acute malnutrition receiving outpatient therapeutic care were concurrently wasted and stunted and had lower recovery rate. The study will inform decision-making on integrated wasting and stunting prevention and treatment policy and programme. This study was funded by Carnegie Corporation of New York through RUFORUM, UNICEF Uganda; and African Union and European Union-Intra-ACP Mobility Partnering for Health Professionals Training in African Universities (P4HPT) and supervised by Assoc. Prof Charles A. S. Karamagi and Dr. Henry Wamani.
Browse Citations by College below:
< Director’s Message | CAES | CoBAMS | CoCIS | CEES | CEDAT | CHS | CHUSS | CoNAS | CoVAB | LAW | MUBS >
You may like
-
CoNAS Participates in the 2025 National Science Week Exhibition
-
Scholarship Opportunity: Impact of Food Supplementation
-
Mirror Frank Kalimuzo’s life of service-MUBS Principal
-
Israeli Ambassador Lotem Talks Innovation on Farewell Visit
-
Makerere Receives Scientific Equipment worth over UGX 1.4 Billion
-
GAMSU Training Workshop Urges CoBAMS academic staff to embrace grant writing
Health
Scholarship Opportunity: Impact of Food Supplementation
Published
2 days agoon
June 16, 2025By
Mak Editor
MAKERERE UNIVERSITY CHILD HEALTH AND DEVELOPMENT CENTER
PhD SCHOLARSHIP FELLOWSHIP TRAINING ADVERTISEMENT
Impact of Food Supplementation on Health, Growth, and Development for Stunted
Children
We are seeking to appoint a full-time PhD Fellow to conduct a randomized controlled clinical trial (RCT) among 300 young children with stunting to assess the effect of Soy Lipid-based Nutrient Supplement with high versus low levels of antinutrients on growth and health of children on a DANIDA-supported project entitled “Climate-resilient soybean for improved growth and health of children in Uganda” (Healthy Soy). The PhD fellow will coordinate the RCT protocol development and its implementation, develop and nest his/her PhD protocol as part-of the RCT study. The PhD student will be hosted at the Child Health and Development Center School of Medicine College of Health Sciences, Makerere University. The PhD student will take part in literature review; designing, planning and conducting of studies; analysing results; writing reports and contributing to technical and policy briefs, journal articles and thesis; project management; organizing research seminars and stakeholder workshops; and guiding junior researchers and teaching. The PhD student will have access to online libraries, scientific databases and software for data analysis throughout their work. In addition, the student will be mentored by national and international researchers to develop scientific research and project management skills with three months stay in Denmark. By the end of the project, the selected candidate will have obtained significant competencies to explain the interactions between nutrition and health of children, growth and development. In addition, the student will gain skills in assessment of body composition, development and conduct of clinical trials design, scholarly writing and presentations, data analysis and interdisciplinary research.
Prospective candidates must:
- Hold Masters in any of the following or equivalents: Human Nutrition, Dietetics, Public
Health Nutrition, Medicine in Paediatrics and Child Health, Public Health or - Epidemiology with undergraduate training in Medicine and Surgery (MBChB/MBBS/MD).
- Having publication experience will be an added advantage.
- Be highly motivated and interested in pursuing rigorous research
- Be committed to a long-term research career in Human Nutrition and Health
- Be of untainted integrity
- Be able to use different software for data analysis and graphics.
Successful fellow will be expected to:
- Conduct high quality research leading to publications in high-impact journals (must be
ready to work towards publishing a minimum of one quality paper per year). - Contribute to research capacity building including training of undergraduate and M.Sc.
students in the host department. - The project will avail financial support to the successful PhD Fellow for 4 years. Funds
will cover: PhD tuition for 4 years; monthly stipend; research supplies and reagents;
conference participation and other research-related costs.
Interested applicants should send an application letter, motivation statement, two
recommendation letters, CV and academic transcripts and certificates for all university
qualifications in an email titled “PhD Fellowship Application – Healthy Soy Project” to
chdc.desk@mak.ac.ug by 26th June 20205.
Female candidates are strongly encouraged to apply. Only shortlisted applicants will be
contacted for interviews.

At a ceremony held on 30th May 2025, themed ‘They taught us without saying a word’, the Makerere University College of Health Sciences (MakCHS) commemorated the silent teacher which are the cadavers (bodies) used in anatomy classes for medical students. In addition to a commemoration service, the event was used to create awareness and sensitise the public about the the importance of whole body donation.
The chief guest at the commemoration was Professor Mukadasi Buyinza, Deputy Vice Chancellor – Academic Affairs representing the Vice Chancellor, Professor Barnabas Nawangwe. The event attended by MakCHS students, staff and alumni was organised by students under Anatomy Society of MakCHS supported by Department of Anatomy and MakCHS leadership.

Welcoming guests to the event, Waziwu Mordecai–final year student of medicine and surgery who serves as President of the Anatomy Society, MakCHS explained that the reason for the gathering is three-pronged: to commemorate the silent teachers who make a profound contribution to medical education; to instill knowledge, compassion, and professionalism in future healthcare providers; and call on the community to support this noble act through awareness, advocacy, or future donation. ‘May the memory of our silent teachers live on in every life we will one day save’, he said.
The Anatomy society was founded in 2013 with aim of students providing peer mentorship to fellow students in lower years, such mentorship sessions help students appreciate better the anatomy of the human body. The society has supported:enhanced learning and mentorship; promoted academic participation including internal and external quizzes; and fostered connections including strengthen relationships between students across classes and with alumni.

Professor Elisa Mwaka, Head – Department of Human Anatomy welcomed all present for attending the ceremony. He thanked the College management led by the Principal, Professor Bruce Kirenga for the support provided in organizing the ceremony. He also expressed utmost appreciation to the Vice Chancellor for attending despite the competing priorities requiring his attention.
Professor Mwaka highlighted that we are here today, to pay our respect to the individuals whose bodies have been used for medical examination and research at MakCHS through offering prayers as well as sensitize people about willful/consented whole body donation.

Professor Mwaka explained that globally, sources of whole bodies for medical education and research are got through willed whole-body donation, unclaimed bodies in hospitals, imported bodies, executed persons among other means. In Uganda, unclaimed bodies in hospitals are used for medical as determined by the Uganda National Rules in the Penal Code Act of 1957.
In 2012 International Federation of Anatomy Associations (IFAA) recommended voluntary donation as the desirable and the only acceptable source for acquiring bodies. Almost all Africa countries and some European countries lack national body donation programs.

Speaking at the event, Professor Bruce Kirenga, Principal – MakCHS thanked Professor Mwaka for the insightful presentation. He welcomed Professor Buyinza to MakCHS and for accepting to attend despite the late invitation. He recognized the presence of the staff present and support towards the college activities.
Professor Kirenga underlined the importance of biomedical science under which human anatomy falls in medical education. ‘Biomedical sciences play a key role, once someone in grounded in the area, then he will be a good doctor’, he said.

The Principal also stressed that during his term of office operation efficiency will remain key ingredient for service delivery as well as rebuilding and rehabilitation of teaching and learning facilities. ‘Works to make the Biochemistry laboratory a model lab has commenced with a contract awarded to service provider; the refurbishment will be in phases’.
Professor Buyinza Mukadasi thanked the College, Human Anatomy department and the students for organizing the commemoration. ‘The amount of joy I have this morning, we should have done this a long time ago’, he said.

He expressed happiness at this commemoration for the silent teachers who unknowingly give so much to medical education and therefore mankind. He advised that community engagement to create awareness about the need for whole-body donation, regulatory compliance, and alignment to best practices.
He noted that disciplines like medicine is more like charity because medical practitioners give so much of themselves. ‘The number of people attending this ceremony is show of love for the discipline and commitment to the calling’ he said.

Professor Buyinza reiterated the commitment of Makerere University management to support MakCHS endeavours including this culture of commemorating the silent teacher. ‘Well-trained and season doctors are a result of the process explained here and the absence of bodies affects the quality of education provided and therefore the doctors produced’, he added.
Candles for the cadavers were lit and services representative of Anglican, Catholics and Muslims were conducted to remember the souls of the departed and wish them a peaceful rest. Ordinand Cosmas Ddembe for Anglican, Father Valentine Amuneke for Catholic and Dr. Haruna Kiryowa for Muslim preached the importance of respect for the dead and sacrifices of the dead for advancement of research and education in the medical field and health services.



Giving closing remarks, Professor Mwaka noted that setting up whole-body donation programs in Africa requires a holistic approach involving education, cultural sensitivity, legal structures, and partnerships with medical institutions.
Reasons why Africa has failed to establish body donation programs:
- Low awareness and willingness to donate bodies.
- Cultural and traditional beliefs
- Religious beliefs
- Fear of mishanding bodies
- Lack of legislation/ ambiguous regulations
- Lack of institutional policies and standard operating procedures
- Institutions should be encouraged to hold Services of thanksgiving or commemoration for those who have donated their bodies for medical education and research.

The following is required to change the current status:
- Cultural sensitivity and awareness
- Community engagement and awareness creation
- Educational campaigns
- Developing legal and ethical frameworks
- Building partnerships between hospitals and medical institutions
- Establishing local body donation systems i.e.,
- donation registration process,
- consent documentation,
- Logistical infrastructure necessary for the
- donation process.
- Effective communication, public trust,transparency.
- Training and professional development of healthcare providers.
- Global collaboration and funding: to share knowledge, best practices, and resources.
- Government support
- Funding and incentives
- Inclusion of body donation in national health strategies.


Health
MakSPH Supports Uganda’s Final Push to End HIV with Locally Led Surveillance
Published
3 weeks agoon
May 30, 2025
In a decisive step toward ending HIV as a public health threat by 2030, Uganda on Thursday, May 29, 2025, officially launched the third Uganda Population-based HIV Impact Assessment (UPHIA 2025) survey, a nationally representative household study expected to provide updated measurements on the status of the HIV epidemic by the end of the year.
The effort is led by Uganda’s Ministry of Health (MoH), with technical assistance from Makerere University School of Public Health (MakSPH), Uganda Bureau of Statistics (UBOS), Uganda Virus Research Institute (UVRI), and the U.S. Centers for Disease Control and Prevention (U.S. CDC), funded by the U.S. government through PEPFAR.
The Population-based HIV Impact Assessment (PHIA) surveys were first launched in 2014 as a global initiative at the International Center for AIDS Care and Treatment Programs (ICAP), based at Columbia University’s Mailman School of Public Health. Supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), through the U.S. CDC, the surveys have been conducted in at least 15 high-burden countries globally, including Uganda.
Led by national Ministries of Health, the PHIA surveys provide robust, population-level data on HIV prevalence, incidence, and viral suppression, offering a clear picture of epidemic trends and the effectiveness of national responses. They are designed to track progress, identify persistent gaps, and inform strategies to reach epidemic control, in line with global targets, including the fast-approaching goal of ending AIDS as a public health threat by 2030.

In Uganda, this survey was first rolled out between August 2016 and March 2017. The second followed in February 2020 but was disrupted by the COVID-19 outbreak, continuing through to March 2021. Both rounds were supported by ICAP at Columbia University, which provided technical assistance to strengthen data collection systems, improve laboratory infrastructure, and build national capacity to design, implement, and analyse the two national HIV surveys.
What sets UPHIA 2025 apart is the shift in technical leadership to Ugandan institutions for this third survey, reflecting local capacity to lead rigorous, high-quality public health research. For UPHIA 2025, Makerere University School of Public Health, in partnership with the Uganda Bureau of Statistics and the Uganda Virus Research Institute, is providing technical leadership to the Ministry of Health, alongside U.S. CDC. Implementation began with initial recruitment and training of over 300 field teams that begun on May 19, 2025, ahead of their nationwide deployment for data collection starting this June.
The first survey (UPHIA 2016) was an important milestone in informing Uganda’s national HIV response. This survey, concluded in 2017, measured, among things, the viral load suppression at the population level and provided household-based HIV testing and counselling, with results returned to participants and those who tested positive referred to care. The survey also assessed HIV incidence, HIV and syphilis prevalence, as well as hepatitis B infection rates. These findings would offer nationally representative data to track Uganda’s progress in controlling the HIV epidemic at both national and regional levels.
The next survey, UPHIA 2020, building on past success, was again executed with technical leadership from Columbia University’s ICAP, working with Uganda’s Ministry of Health alongside UVRI, UBOS, regional referral hospitals, local governments, and the U.S. CDC. It offered useful insights that showed encouraging progress, indicating that up to 88% of people living with HIV in Uganda at the time knew their status, 98% of them were on treatment, and 90% had achieved viral suppression. These results reflected momentum toward the UNAIDS global 95-95-95 targets, ensuring that most people living with HIV are diagnosed, treated, and have the virus under control, and advancing the broader goal of ending the epidemic by 2030.
Since the release of these findings nearly five years ago, which helped shape national HIV programming in Uganda, the country has made notable progress, but challenges remain. The UPHIA 2020 findings reported major gaps in testing coverage, particularly among young people and men. The results were also instrumental in identifying service delivery shortfalls and guiding decisions on resource allocation, program design, and policy. Yet today, Uganda remains one of the most heavily burdened countries in the world, with over 1.5 million people living with HIV and over 50,000 preventable new infections recorded per year.

It is this trend that Uganda’s Ministry of Health is working urgently to reverse. Launching UPHIA 2025 at the Ministry’s headquarters in Kampala on May 29, 2025, amidst great hope and expectation among the participants, Uganda’s Minister of Health, Dr. Jane Ruth Aceng Ocero, noted that the long-anticipated and previously delayed survey had arrived at such a critical moment. She welcomed UPHIA 2025 as both a measure of the country’s resilience and a guide for the final stretch toward ending AIDS by 2030, now just a few years away.
“The UPHIA 2025 survey comes at a strategic time to help us recalibrate and refocus our efforts,” the Health Minister said, underscoring the importance of its outcomes. “This will be Uganda’s final population-based HIV survey before 2030, the target year for ending AIDS as a public health threat. The findings will serve as a baseline for tracking our progress toward this national and global goal. They will also guide the next phase of strategic planning, ensuring that the final push toward 2030 is grounded in robust and reliable data.”
This third round of the survey will be carried out in 6,685 randomly selected households across the country. The exercise will involve interviews with approximately 15,000 individuals aged at least 15 and selected through a national household listing by UBOS. Of those, around 14,980 are expected to provide blood samples for HIV testing and analysis of viral suppression and other health indicators. The survey will also include interviews with 1,300 children and adolescents aged 10 to 14, though no blood draws will be taken from this group. Participation is voluntary, free of charge, and requires consent from the head of each household.

Dr. Aceng explained that beyond providing updated estimates of HIV prevalence, incidence, and viral load suppression, and examining regional and demographic disparities, the survey, which will cover the rest of the year, will include a qualitative post-survey assessment component to gather insights from people living with HIV, particularly those not virally suppressed, to understand their challenges and strengthen support services. Also, for the first time, this survey will assess the burden of non-communicable diseases among people living with HIV and include focused interviews with adolescents aged 10 to 14 in Mid-North and Mid-Eastern Uganda, where viral suppression was reported to be lowest in UPHIA 2020.
These activities are made possible thanks to the development support from the U.S. government, which invested $10 million (about UGX 37 billion) for this survey. Speaking at the UPHIA 2025 launch, U.S. Ambassador to Uganda William W. Popp noted that the United States has partnered with Uganda for over three decades to help people live longer, healthier lives;
“The bulk of our annual support, approximately $500 million this year, is dedicated to health programs, making the U.S. government the largest single provider of health assistance to Uganda,” the Ambassador said. He added, “Through PEPFAR, the United States has played a major role in Uganda’s progress toward ending HIV as a public health threat. Since 2003, when Uganda became one of the first countries to implement the program, we have invested nearly three billion dollars—almost 11 trillion Uganda shillings—in HIV prevention, care, and treatment services, saving millions of lives and making both our countries safer from HIV.”

With the benefit of hindsight, Uganda’s early encounter with HIV in the 1980s marked the beginning of one of the region’s most severe epidemics. But over the decades, a determined national response, driven by political leadership, community mobilisation, collaboration and global support, has delivered measurable progress. In the recent past, adult HIV prevalence fell from 7.2% in 2010 to 5.1% in 2023. Among women, it declined from 8.5% to 6.6%, and among men from 5.8% to 3.6%. AIDS-related deaths dropped from 53,000 to 20,000 over the same period, with female mortality declining by 66% and child deaths by 77%.
All these gains, amidst the challenge, go to show what is possible with sustained commitment. What is more, throughout this long journey of Uganda’s battle with eradicating HIV, Makerere University School of Public Health has played a pivotal role. From the early work of Prof. David Serwadda, whose ground-breaking research during the initial detection of HIV helped shape Uganda’s early response, to last year’s 2024 landmark Purpose 1 study on the twice-yearly injectable Lenacapavir that proved 100% efficacy in preventing HIV infection, MakSPH has remained at the forefront of innovation, evidence generation, and policy influence.
That legacy continues today, with the School providing technical leadership to the Ministry of Health in the implementation of UPHIA 2025. At the launch, MakSPH Dean Prof. Rhoda Wanyenze expressed pride in the School’s role as a trusted partner in Uganda’s fight against HIV and other public health challenges. She noted that for over 70 years, during which the School has existed, MakSPH has helped shape the country’s public health landscape through rigorous research, training, and policy support, anchored by a strong, long-standing partnership with the Ministry of Health and partners.

She also noted that the collaboration between Makerere University and the U.S. CDC has helped build national capacity in surveillance and epidemiology, while also strengthening Uganda’s ability to lead high-quality, large-scale national surveys, asserting that:
“The partnership between Makerere University and CDC has not only helped build national capacity in surveillance and epidemiology, but has also strengthened our ability to lead high-quality, large-scale national surveys. After two decades of joint work, we are proud that UPHIA 2024–2025 is now a fully Ugandan-led effort. This is critical to the sustainability of the skills and knowledge generation to inform our local response.”
The survey builds on MakSPH’s experience conducting similar national studies, including those on tuberculosis, prison health, family planning, schistosomiasis, and non-communicable diseases such as the STEPS survey. It will leverage the School’s strong capacity in research and impact evaluation, both in Uganda and across the African region, with a firm commitment to delivering high-quality data guided by the same rigour and integrity that have defined our work over the years, Prof. Wanyenze affirmed.
Trending
-
General5 days ago
Mirror Frank Kalimuzo’s life of service-MUBS Principal
-
Research1 week ago
Mak and MSU Host Landmark Symposium on Insects for Food, Feed, and Food Security in Africa
-
General1 week ago
Israeli Ambassador Lotem Talks Innovation on Farewell Visit
-
Business & Management2 weeks ago
GAMSU Training Workshop Urges CoBAMS academic staff to embrace grant writing
-
General6 days ago
Directorate of Graduate Training Rolls out Research Management Information Sytems (RIMS)