General
Mak 70th Grad PhD Citations Session 1, Part 3
Published
7 years agoon
College of Health Sciences (CHS)
BBOSA Nicholas
A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda
Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.
BWIRE Godfrey
Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.
Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).
EGESA Moses
Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens
Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.
KADDUMUKASA Martin
Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda
Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.
KAYIMA James
Hypertension in Uganda: epidemiology and association with HIV infection and genetics
Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.
MBOOWA Gerald
Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana
Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.
MPIMBAZA Arthur Mwambari
Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda
Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.
NABATANZI Rose (Ms)
Innate immune system recovery after long-term antiretroviral therapy in an African cohort
Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.
NAJJUKA Christine Florence (Ms)
Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda
Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.
ZIDA Andre
Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system
Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.
Please click the links below to navigate to the PhD Citations for the respective Sessions.
< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >
#Mak70thGrad
You may like
General
Students with Disabilities Trained on Assistive Technology Use for Learning
Published
8 hours agoon
August 31, 2026
For 60 students with disabilities, a computer, Braille reader or scanner is more than just a piece of equipment. It can be the difference between struggling to access information and learning with greater independence.
The students recently received practical training on the use of assistive technology to help them navigate their studies and university life with fewer barriers.
The one-day training was held on Saturday, August 22, 2026, at the Disability Support Centre in the Frank Kalimuzo Building. It was organised by the Dean of Students’ Office in partnership with the Mastercard Foundation Scholars Program at Makerere University and the Makerere University Disabled Students Association (MUDSA).

Unlike a classroom lecture, the training was largely hands-on. Students were taken through different technologies available at the University and given an opportunity to learn how they can use them in their day-to-day academic work.
Assistive technology includes devices, software and other tools that help people with disabilities access information, communicate, study and perform everyday tasks more independently.
Learning without barriers
Ms Elizabeth Rwabu, the Inclusion Support Services Officer at the Mastercard Foundation Scholars Program, encouraged students, particularly first-years, to make use of the Disability Support Centre.
“For first-year students, university is a new chapter, and none of you should feel that you have to navigate it alone. Familiarise yourselves with the services at the Centre and seek support whenever they need it,” Ms. Rwabu, said.

Ms. Rwabu also reminded the students to take care of the equipment, saying the facilities are shared by many students.
“These computers and assistive technologies are not simply pieces of equipment; they are tools that open doors to learning, communication and independence,” she said.
Students introduced to Braille technology
Mr Binasali Kyebagadha, an assistive technology expert from the Kyambogo University Disability Support Centre, led the practical session. He introduced students to the ethical use of assistive technology and demonstrated how different devices can support learning.
Among the devices demonstrated were the Orbit Reader 40 and Focus Blue 40 refreshable Braille displays, as well as the Pearl scanner.
Students were also shown how to use a smart interactive board and how it can support learners with different disabilities.

Mr. Kyebagadha told the students that assistive technology should be seen as a tool for independence.
“Assistive technology is meant to remove barriers, not create dependence. When properly used, it gives a student the confidence and independence to learn, communicate and participate on an equal footing with others,” he said.
He also cautioned the students against misusing the equipment, noting that the devices are shared resources.
Disability Support Centre
The training comes as Makerere continues to strengthen its Disability Support Centre, which provides a range of services to students with disabilities.
The Centre has computers fitted with screen readers such as JAWS and Fusion, Braille embossing services, large-print materials, refreshable Braille displays and audiobook reading services.
For students with visual and hearing impairments, such services can make access to learning materials easier and improve their participation in university activities.

The Centre also provides a link between students and academic staff, helping to address challenges that may affect students’ participation in learning.
Makerere established the Disability Support Centre as part of its efforts to promote an inclusive learning environment. The University also adopted its Policy on Persons Living with Disabilities in 2022.
For the students who attended the training, the most important takeaway was whereas having the right technology is useful, knowing how to use it can make an even bigger difference.
As Makerere expands its support for students with disabilities, the focus is increasingly moving beyond providing equipment to ensuring that students have the skills and confidence to use the technology effectively.
General
Uganda to Launch ACT-PREP, Africa’s New Epidemic Preparedness Research Network
Published
3 days agoon
August 28, 2026By
Mak Editor
By Henry Mugenyi
When the next infectious disease outbreak strikes, the question for African researchers should not be whether they have the capacity to conduct the research, but how quickly they can begin.
That is the gap a new five-year research initiative, Advancing Clinical Trials and Epidemic Preparedness Research Capacity in Africa (ACT-PREP), is seeking to address.
The project will be officially launched in Uganda on September 28th, 2026, bringing together researchers and partners from universities and research institutions across Africa and Europe. The launch will be held at the Makerere University School of Public Health (MakSPH) Auditorium in Kampala.
Led by Makerere University School of Public Health, ACT-PREP is designed to strengthen Africa’s ability to conduct clinical trials and other research before and during infectious disease outbreaks.
Africa has repeatedly faced epidemics of diseases such as Marburg, Ebola, COVID-19 and other emerging infections. Yet when outbreaks occur, the capacity to quickly generate the evidence needed to guide treatment, prevention and public health decisions remains underdeveloped.
ACT-PREP aims to make research part of outbreak preparedness not something that begins only after an epidemic has already spread.
According to Prof Rhoda Wanyenze, the Principal Investigator on the project, “the initiative will establish a framework for more equitable collaboration among 10 African and two European institutions, working alongside Universities and the Africa Centres for Disease Control and Prevention (Africa CDC)”.
The consortium includes institutions from Uganda, Rwanda, Tanzania, the Democratic Republic of Congo, Somalia, South Sudan and Senegal, as well as European partners in Sweden and Germany. Africa CDC is also among the participating institutions.
For Uganda, the launch at Makerere University is significant. The university is taking the scientific lead on a programme that places African research institutions at the centre of efforts to prepare for future epidemics.
One of ACT-PREP’s central ambitions is to address the shortage of researchers and systems capable of rapidly conducting high-quality clinical research during emergencies.
The project will strengthen clinical research, ethics and regulatory capacity, while also supporting laboratory and disease surveillance systems. It will integrate training into PhD and postdoctoral programmes, with the consortium aiming to train at least 700 fellows at the end of the project.
“The idea is straightforward: Africa needs not only laboratories and equipment, but also people with the skills to use them when an outbreak begins” – Says Dr Steven Kabwama, ACT-PREP Project Manager.
Researchers will also be supported to share expertise, data, resources and technology across institutions and national borders.
ACT-PREP will further explore One Health approaches and artificial intelligence-supported systems to improve disease prediction, detection and rapid response. The project also seeks to support more streamlined regulatory processes so that clinical trials can be deployed and monitored more quickly when they are needed.
The experience of recent epidemics has shown that time is one of the most valuable resources in an outbreak.
Delays in detecting a pathogen, setting up research sites, securing ethical and regulatory approvals or generating reliable evidence can affect how quickly health authorities are able to respond.
ACT-PREP is built around the idea that many of these systems should already be in place before the next emergency.
That means having trained researchers, functioning laboratories, established regulatory pathways, surveillance systems and relationships between institutions that can be activated when an outbreak occurs.
It also means changing how research partnerships are built.
Rather than relying on external institutions to arrive when a crisis begins, the project seeks to strengthen African institutions themselves and create longer-term collaborations in which expertise, technology, data and resources can be shared across borders.
After 14 years of dedicated service, Claire Nakayiza, a familiar face and trusted custodian at the School of Public Health (SPH), has retired, leaving behind a legacy of hard work, commitment, kindness and service to the School community.
For many people at the School of Public Health, the sight of Claire arriving early in the morning, opening up the building and ensuring that everything was in order was simply part of the daily rhythm of life at the School.
For 14 years, Claire has been a constant presence at SPH. She has witnessed generations of staff, students, researchers and visitors walk through the School’s doors. She has seen colleagues join, grow and eventually move on, while she remained a dependable presence, quietly carrying out her responsibilities and ensuring that the School was ready to welcome everyone each day.
Her retirement was therefore more than a routine farewell. It was an opportunity for colleagues to celebrate a woman whose contribution, though often carried out behind the scenes, touched many lives and contributed significantly to the smooth running of the School.

At a farewell brunch organised by the Dean, School of Public Health, Prof. Rhoda Wanyenze, colleagues and friends described Claire in glowing terms. Words such as hardworking, kind, patient, resilient, dependable and caring repeatedly featured in the tributes.
For many, Claire was much more than a custodian. She was described as a mother figure, a counsellor and someone people could approach whenever they needed a listening ear, encouragement or simply a warm smile.
A commitment that went beyond the call of duty
One of the strongest themes to emerge during the farewell was Claire’s extraordinary commitment to her work.
Colleagues recalled how she would routinely open the School building as early as 6:00 a.m., ensuring that staff and students arriving for the day found the premises ready. Her working day could stretch well into the evening, with some days requiring her to remain at the School until 8:00 p.m. or even 10:00 p.m.
Despite the long hours and demanding nature of her responsibilities, colleagues said Claire rarely complained. Instead, she approached her work with patience and resilience, always focused on ensuring that the School was secure and that its operations could continue smoothly.
Her dedication was particularly evident in her contribution to improving the security of the School building. Over the years, Claire became a trusted custodian of the premises, helping to ensure that the building was opened and closed responsibly and that the environment remained secure for those who worked and studied there.
Speaking at the farewell, Prof. Wanyenze described Claire as someone who consistently worked beyond the call of duty.

The Dean acknowledged that saying goodbye to Claire was an emotional moment, given the many years she had spent serving the School and the relationships she had built along the way.
However, Prof. Wanyenze said she had spoken to Claire and was assured that she was ready to embrace the next phase of her life.
She joined colleagues in wishing Claire good health, happiness and prosperity as she begins her retirement journey.
More than a custodian
Claire’s impact at SPH was not limited to the physical responsibilities associated with her job. To those who interacted with her regularly, her greatest contribution was perhaps the warmth and humanity she brought to the workplace.
Amos Ddembe, the Internal Auditor, described Claire as a joy to watch as she went about her work.
He particularly remembered her interactions with people when she was stationed at the reception area. Claire, he noted, was almost always smiling and welcoming to staff and visitors.
Her ability to make people feel comfortable, regardless of their position or role at the School, earned her the affection and respect of many colleagues.
Claire’s colleagues also remembered her as someone who was willing to listen and offer guidance. Her patience and calm demeanour meant that people could approach her with their concerns, knowing they would receive a sympathetic ear.
Over the years, these seemingly small interactions accumulated into meaningful relationships, helping to make Claire one of the most recognisable and trusted members of the SPH community.
A legacy of service
Fourteen years is a significant period in the life of any institution. During that time, Claire witnessed changes in leadership, staff, students, programmes and the physical environment of the School.
She remained a constant through these transitions.
Her service represents the important contribution made by members of the support staff whose work often happens quietly but is essential to the functioning of an institution.
From opening the building before sunrise to securing it late in the evening, welcoming people at reception, supporting the day-to-day operations of the School and contributing to the security of the premises, Claire’s work helped create an environment in which others could perform their own responsibilities.

Her story is a reminder that the success of an institution is built not only through high-profile academic and research achievements, but also through the dedication of people who ensure that the institution functions every day.
A gesture of appreciation
As part of the farewell, the Department of Community Health and Behavioral Sciences also expressed its appreciation for Claire’s years of service.
Representing the Department, Dr. Christine Nalwadda presented Claire with a cash envelope on behalf of the staff as a token of appreciation for her commitment and contribution to the School.
A new chapter begins
As Claire leaves the School of Public Health, she takes with her the memories of 14 years of service and the goodwill of the many people she encountered along the way.
For the colleagues who gathered to celebrate her, the farewell was not simply about marking the end of employment. It was about celebrating a colleague who had become part of the fabric of the School.
As she begins this new chapter, the School of Public Health joins together in saying:
“Thank you, Claire, for 14 years of dedicated service. Thank you for the early mornings, the long evenings, the smiles, the patience and the unwavering commitment.
May retirement bring you the good health, peace, happiness and prosperity you so richly deserve.”
Trending
-
General1 week agoUndergraduate Admission Lists 2026/2027
-
General2 weeks ago72 Makerere University Students Admitted to 2026 Millennium Fellowship
-
Computing & IS2 weeks agoCall For Applications: Mak-AI PhD Fellowship
-
Business & Management1 week agoMakerere University Inaugural Conference on Noonomy Paves way for Centre of Excellence in Africa
-
Law2 weeks agoMakerere University School of Law Finishes Second at 35th Christof Heyns All Africa Human Rights Moot Competition