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Mak 70th Grad PhD Citations Session 1, Part 3

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College of Health Sciences (CHS)

 

BBOSA Nicholas

A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda

Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.

 

BWIRE Godfrey

Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.

Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).

 

EGESA Moses

Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens

Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.

 

KADDUMUKASA Martin

Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda

Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.

 

KAYIMA James

Hypertension in Uganda: epidemiology and association with HIV infection and genetics

Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.

 

MBOOWA Gerald

Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana

Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.

 

MPIMBAZA Arthur Mwambari

Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda

Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.

 

NABATANZI Rose (Ms)

Innate immune system recovery after long-term antiretroviral therapy in an African cohort

Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.

 

NAJJUKA Christine Florence (Ms)

Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda

Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.

 

ZIDA Andre

Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system

Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.

 

Please click the links below to navigate to the PhD Citations for the respective Sessions.

< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >

#Mak70thGrad

Mark Wamai

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Makerere University Newsletter Jan-Mar 2026

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Cover Page of the Makerere University Newsletter Jan-Mar 2026. Kampala Uganda, East Africa.

The activities of the first quarter of 2026 depict Makerere University not just as a place of learning but as a dynamic space where ideas, ambition, and opportunity shape the future.

This edition highlights a university in motion. The Career Fair 2026 stood out as a powerful moment of reflection and discovery. Under the theme “Machine vs. Man,” students were challenged to rethink their place in a rapidly evolving world shaped by artificial intelligence. What emerged was not fear, but clarity a recognition that the future belongs to those who are adaptable, innovative, and willing to learn continuously. Beyond the discussions, the fair created meaningful connections, opening pathways to careers, further study, and entrepreneurship.

The launch of the Open, Distance and eLearning (ODeL) initiative is a practical step toward inclusive and accessible education. By embracing digital transformation, Makerere is expanding learning beyond physical classrooms and positioning itself as a leader in flexible, technology-driven education. This shift reflects a broader commitment to ensuring that quality education reaches more learners, within Uganda and beyond.

This issue also celebrates the people behind the progress. From staff committing wholeheartedly to the student community they serve to student leaders navigating complex challenges, the stories this quarter demonstrate the personal resilience, creativity, and purpose that drive the institutional transformation at the Hill.

Eunice Rukundo,
Deputy Chief, Public Relations.

Mak Editor

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How to deal with Examination Fever

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Prof. Buyinza Mukadasi and other officials pose with students for a group photo after the pre-examination mental health workshop on 15th May 2026. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.

Today, Monday 18th May 2026, most students will begin their End of Semester Two Examinations, and they have been encouraged to remain confident and calm during the examination season.

Data from the University Counselling and Guidance Centre shows that even the best-prepared students experience anxiety, pressure, fear of failure, sleep difficulties and emotional exhaustion during examinations.

Addressing students during a pre-examination mental health workshop organised by the Mastercard Foundation Scholars Program at Makerere University on 15th May 2026, Prof. Buyinza Mukadasi, Academic Registrar, reminded students that their mental health is far more important than any grade.

 “This workshop comes at the right time. I encourage all students to understand that your worth is not defined by a single examination or grade. Examinations are only one part of your educational journey. What matters equally is your ability to remain healthy, focused, ethical and hopeful throughout the process,” Prof Buyinza, said.

Prof. Buyinza shared practical tips to help students avoid fatigue and excessive stress during this period.

Prof. Buyinza Mukadasi. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi.

“Prepare a realistic reading timetable and avoid last-minute cramming. Take short breaks while studying to allow your mind to recover and improve concentration. Get adequate sleep and avoid excessive consumption of caffeine and energy drinks,” he noted.

During the session, he also encouraged students to engage in light physical activity, stretching or short walks to refresh their minds and reduce tension.

“Maintain a positive mindset and avoid comparing yourself excessively with others. Stay connected with supportive friends, family members, mentors or counsellors whenever you feel overwhelmed,” Prof. Buyinza advised.

He reaffirmed the University’s commitment to supporting students not only academically, but also in their mental and psychosocial wellbeing, encouraging learners to seek help from counsellors, lecturers, mentors, peers, family members and available support systems whenever necessary.

Speaking at the event, Ms. Prossy Nakayiki, the Deputy Academic Registrar in charge of Examinations and Transcripts warned students against examination malpractice and urged them to uphold academic integrity.

Ms. Prossy Nakayiki. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.
Ms. Prossy Nakayiki.

 “Anxiety should never push anyone into examination malpractice, do not enter an examination room with a smart watch, phone or any hidden paper commonly known as bullets. Preparation, honesty, rest and self-belief remain the best approaches to success,” Ms. Nakayiki, said.

She also advised students who had not yet printed their examination cards to do so early, noting that delays at the last minute could cause unnecessary panic and disorganisation.

In her presentation about the reality of examination stress and coping strategies, Connie Evelyn Kharono, a Counselling Psychologist at the Counselling and Guidance Center, called upon students to adopt the 5, 4,3,2,1 Ground technique before an exam or intense study session.

Ms. Connie Evelyn Kharono. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.
Ms. Connie Evelyn Kharono.

The 5, 4,3,2,1 ground technique, is one of the easiest mindfulness strategies designed for managing stress and anxiety, as it can be done almost anywhere and at any time. You name 5 things you can see, 4 you can touch, 3 you can hear, 2 you can smell and 1 you can taste.

She advised students to focus on what they can control.

“You can control your study schedule, your sleep and how kindly you speak yourself. You cannot control the exact questions that will be on the paper, so channel your energy only into the preparations you can influence,” Ms Kharono, said.

Students participate during the workshop. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.
Students participate during the workshop.

Ms Kharono encouraged students to maintain a regular sleep schedule and ensure that they are eating balanced meals and staying hydrated.

Ms Christine Nimusiima, a senior Psycho-Social Officer at the Mastercard Foundation Scholars Program at Makerere University, called upon the students to practise positive self-talk and maintain a healthy mindset.

Part of the audience at the workshop. Pre-End of Semester Two Examinations 2026/2026 mental health workshop organised by the Mastercard Foundation Scholars Program, 15th May 2026, Yusuf Lule Central Teaching Facility Auditorium, Makerere University, Kampala Uganda, East Africa.
Part of the audience at the workshop.

“During this examination season, avoid comparing your revision progress or predicted grades with your peers. Your only competition is who you were yesterday. Take a deep breath, trust in the work you have done and remember that you have the resilience to succeed. Best of luck with your preparations,” Ms. Nimusiima said.

Carol Kasujja
Carol Kasujja Adii

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AAP Africa Office Hosts UiB Research and Innovation Delegation

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Dr. Racheal Ddungu Mugabi (2nd L) poses for a group photo with the Head GAMSU and UiB delegation on 14th May 2026. Alliance for African Partnership (AAP), Africa Office hosts delegation from the University of Bergen (UiB)'s Division of Research and Innovation, 14th May 2026, Yusuf Lule Central Teaching Facility, Makerere University, Kampala Uganda, East Africa.

By Dr. Racheal Ddungu Mugabi

The Alliance for African Partnership, Africa Office, today received a delegation from the University of Bergen (UiB)’s Division of Research and Innovation. The visiting team comprised Kristin Svartveit, Vivil Valvik Haraldsen, and Emmanuel Ovon Babatunde.

The delegation was officially introduced by Prof. Sylvia Antonia Nakimera Nannyonga-Tamusuza, Head, Grants Administration and Management Support Unit (GAMSU), together with Dr. Ronald Semyalo (Makerere University coordinator for UiB)

The visit aimed to strengthen institutional collaboration and promote research excellence through international partnerships. The key objectives of the meeting included:

  1. UiB team sharing information and experiences on enhancing success in EU grant acquisition and management.
  2. UiB application support process for Postdoc fellowships at Bergen up to a period of 2 years
  3. AAP Africa Office providing insights into the AAP consortium programs and activities in order to foster collaboration between the AAP consortium and UiB.
L-R: Dr. Ronald Semyalo, Emmanuel Ovon Babatunde, Kristin Svartveit, Vivil Valvik Haraldsen, Prof. Sylvia Antonia Nakimera Nannyonga-Tamusuza and Dr. Racheal Ddungu during the engagement. Alliance for African Partnership (AAP), Africa Office hosts delegation from the University of Bergen (UiB)'s Division of Research and Innovation, 14th May 2026, Yusuf Lule Central Teaching Facility, Makerere University, Kampala Uganda, East Africa.
L-R: Dr. Ronald Semyalo, Emmanuel Ovon Babatunde, Kristin Svartveit, Vivil Valvik Haraldsen, Prof. Sylvia Antonia Nakimera Nannyonga-Tamusuza and Dr. Racheal Ddungu during the engagement.

The engagement provided an important platform for knowledge exchange, networking, and exploring opportunities for future collaborative research initiatives between Makerere University, the AAP consortium, and the University of Bergen.

The Author is the Director of the AAP Africa Office

Mak Editor

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