General
Mak 70th Grad PhD Citations Session 1, Part 3
Published
7 years agoon
College of Health Sciences (CHS)
BBOSA Nicholas
A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda
Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.
BWIRE Godfrey
Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.
Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).
EGESA Moses
Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens
Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.
KADDUMUKASA Martin
Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda
Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.
KAYIMA James
Hypertension in Uganda: epidemiology and association with HIV infection and genetics
Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.
MBOOWA Gerald
Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana
Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.
MPIMBAZA Arthur Mwambari
Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda
Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.
NABATANZI Rose (Ms)
Innate immune system recovery after long-term antiretroviral therapy in an African cohort
Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.
NAJJUKA Christine Florence (Ms)
Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda
Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.
ZIDA Andre
Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system
Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.
Please click the links below to navigate to the PhD Citations for the respective Sessions.
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General
JICA, Makerere University Explore New Frontiers in AI and Research Collaboration
Published
7 hours agoon
September 4, 2026By
Mak Editor
By Moses Lutaaya
Kampala, September 4, 2026 — Makerere University and the Japan International Cooperation Agency (JICA) have explored new opportunities for strengthening academic, research and innovation collaboration between Uganda, Japan and other African countries, with a particular focus on artificial intelligence (AI), aerospace engineering, materials and remote sensing, food value chains, energy, water and climate change.
The discussions took place on Friday, September 4, 2026, at the Makerere University Main Building in the Vice Chancellor’s Board Room, during a visit by a JICA delegation led by Dr. Okano Takasei, Senior Advisor, Human Development Department of JICA.
Makerere keen to deepen collaboration with JICA
Welcoming the delegation, the Deputy Vice Chancellor (Academic Affairs), Prof. Sarah Ssali, highlighted Makerere University’s long-standing tradition of research, international collaboration and contribution to knowledge generation in Uganda and beyond.
Prof. Ssali noted that Makerere has built a strong global research footprint through partnerships with institutions around the world, observing that the University is well positioned to deepen international collaboration as emerging technologies, particularly artificial intelligence, continue to transform research and higher education.
“Uganda has a very long history of doing research, and particularly it has informed research findings in the areas global health research,” Prof. Ssali said, pointing to Uganda’s historical contribution to global scientific knowledge.
She cited the country’s contribution to medical and biological research, including early research on sleeping sickness, noting that Uganda’s unique research environment continues to offer opportunities for scientific discovery.
Prof. Ssali said Makerere’s history of collaboration with Japan is particularly significant, noting that Japanese cooperation has contributed not only to academic and research activities but also to infrastructure development and other sectors in Uganda.
She cited the establishment of the JICA building at Makerere, describing it as one of the visible symbols of Japan’s long-standing partnership with Makerere University.

According to Prof. Ssali, the building, which houses College of Natural Sciences (CoNAS) disciplines of geology, petroleum studies and administrative offices, was constructed during her undergraduate years and completed within a remarkably short period.
Prof. Ssali said the long-standing relationship between Uganda, Makerere University and Japan provides a strong foundation upon which new areas of collaboration can be built. She encouraged the visiting JICA delegation to explore the University and identify areas where existing partnerships could be strengthened or new areas of cooperation developed.
“Please take time and explore and see where either you already have a footprint, where you’ve ever had a footprint, or where you could explore new areas,” she said.
Prof. Ssali added that Makerere was privileged to host the JICA delegation and expressed optimism that the visit would lead to meaningful and sustainable partnerships.
Strengthening Joint Collaboration through AJ-ASPIRE
Dr. Okano, in his remarks as leader of the delegation said the visit formed part of a broader JICA initiative aimed at promoting academic and research collaboration between Japanese and African universities.
He explained that the initiative was launched on the occasion of the ninth Tokyo International Conference on African Development (TICAD 9), held in Yokohama in September 2025, with the objective of strengthening academic and research partnerships between Japan and Africa.
According to Dr. Okano, the initiative is intended to benefit both African and Japanese universities by providing platforms for internationalisation, collaborative research and the exchange of knowledge, researchers and students. “We would like to play a role of facilitator between universities in Japan and Africa and Uganda as well,” he said.
He explained that JICA is currently promoting the initiative through three African hub universities where JICA already has ongoing projects and experts on the ground.
The three institutions are Egypt-Japan University of Science and Technology (E-JUST) in Egypt, Jomo Kenyatta University of Agriculture and Technology (JKUAT) in Kenya, and Stellenbosch University in South Africa.
Dr. Okano said the selection of the three institutions was informed by the presence of ongoing JICA-supported projects and experts who can facilitate collaboration between the hub universities and institutions across Africa and Japan.

The hub universities are currently coordinating research with Japanese universities in strategic areas, with E-JUST focusing on energy, JKUAT leading work on food value chains, and Stellenbosch University focusing on water and climate change.
Dr. Okano said JICA was particularly pleased to explore collaboration with Makerere University under the African-Japan Initiative for Research and Education Partnerships, known as AJ-ASPIRE.
He outlined three major avenues through which Makerere could participate in the initiative.
The first is participation in existing research programmes hosted by the three hub universities. He added that Makerere researchers could join ongoing research on energy, food value chains, water and climate change, thereby creating opportunities to work with Japanese and other African researchers.
“We would like to explore opportunity for researchers from Makerere University to participate in these ongoing research activities and expand collaboration with Japanese and African partner institutions,” Dr. Okano said.
The second area is the development of new research networks in artificial intelligence and aerospace engineering. Dr. Okano said JICA was planning to establish new research groups focusing on the two areas and would be interested in having Makerere researchers participate in the emerging networks. “We would like to also invite researchers from Makerere University to join these networks and implementation of future collaboration in these two research topics, aerospace engineering and AI,” he said.
The third proposed avenue is increased collaboration between Makerere University and E-JUST, which Dr. Okano said offers fully funded scholarship opportunities for African students through a programme jointly supported by the governments of Egypt and Japan.
He noted that a number of Makerere graduates have already benefited from the programme, including researchers who have pursued doctoral studies and research opportunities in Egypt and Japan.
Dr. Okano cited the example of Mr. Abdonoor Kalibala, a Makerere alumnus whom he recently met in Hiroshima, Japan, following completion of PhD in Mechatronics and Robotics engineering at E-JUST. Mr. Kalibala conducted research in Japan for up to six months under the supervision of a Japanese professor as part of his doctoral programme.
Dr. Okano said such programmes could help strengthen the movement of researchers between Uganda, Egypt and Japan and create lasting institutional partnerships.
He added that JICA is also providing small research grants to alumni of the programmes to help them maintain and expand research collaboration involving Japan, E-JUST and African institutions.
He said Makerere could leverage such opportunities to increase the participation of its students and researchers in international research networks.
AI, Materials and Remote Sensing and International Relations Set the Pace
Prof. Robert Wamala, Director of Research, Innovations and Partnerships at Makerere University, said the visit followed an online engagement held a few weeks earlier between Makerere University and JICA, during which several areas and units within the University were identified as potential points of collaboration.
Prof. Wamala said these included the Makerere University AI Lab, the University’s International Office and researchers working in space engineering, particularly in materials and remote sensing.
He welcomed the transition from online discussions to physical engagement, saying the visit would allow JICA representatives to interact directly with researchers, academic units and University authorities. “This interest is being followed up through an in-person visit, which provides us an opportunity for JICA to engage directly with the relevant units and researchers at Makerere University,” Prof. Wamala said.
For Makerere, he added, the initiative provides an opportunity to connect the University’s research strengths with Japanese universities, research institutions and development partners to address shared development challenges.

Prof. Wamala said the University was particularly interested in identifying practical areas of collaboration that could move beyond general discussions to concrete research partnerships, joint projects and opportunities for students and researchers.
He noted that the JICA delegation’s on-campus interactions scheduled to take place throughout the day would enable the two sides to identify specific areas of mutual interest. “We hope these engagements will help us identify specific areas of future interest and provide a basis for developing concrete areas of collaboration under the AJ-ASPIRE,” Prof. Wamala said.
He reiterated Makerere’s commitment to strengthening international research partnerships and thanked JICA for its continued interest in the University.
Dr. Okano, was accompanied by Mr. Ito Idomu, Research and Advisor at the Embassy of Japan, Mr. Osaki Mistuhiro from JICA headquarters, Ms. Eric Maeda from JICA Headquarters, and Ms. Ruth Mbabazi from JICA Uganda.
JICA follow-up meetings with Makerere research units
Following the high-level meeting in the Vice Chancellor’s Board Room, the JICA team, together with the Directorate of Research, Innovations and Partnerships, proceeded to engage with key research and administrative units at Makerere University identified as strategic to the proposed areas of collaboration.
The delegation held meetings with the Makerere University AI Lab, led by Dr. Joyce Nabende of the College of Computing and Information Sciences (COCIS), to explore opportunities for cooperation in artificial intelligence and related emerging technologies.
The team also met officials from the Makerere University International Office, led by Mr. Mathias Ssemanda, where discussions focused on opportunities for strengthening international academic linkages, mobility and institutional partnerships.
A further engagement was held with the Department of Geomatics and Land Management, focusing on materials and remote sensing, led by Prof. Lydia Kayondo from the College of Engineering, Design, Art and Technology (CEDAT).
The engagements provided an opportunity for the JICA team and Makerere researchers to move from broad discussions on collaboration to more specific conversations around research interests, expertise, existing projects and potential areas for joint work.
The visit marks an important step towards strengthening Makerere University’s engagement with Japanese and African research institutions under AJ-ASPIRE, while opening opportunities for researchers and students to participate in emerging international networks in artificial intelligence, aerospace engineering, remote sensing and other strategic areas of science, technology and innovation.
General
Undergraduate Admissions: Students allowed to Change Programs/Subjects 2026/27
Published
2 days agoon
September 2, 2026By
Mak Editor
The Office of the Academic Registrar has released lists of students whose applications for change of Programme/Subjects have been approved for the Academic Year 2026/2027.
The lists can be accessed by following the inks below:
General
Uganda to Launch ACT-PREP, Africa’s New Epidemic Preparedness Research Network
Published
1 week agoon
August 28, 2026By
Mak Editor
By Henry Mugenyi
When the next infectious disease outbreak strikes, the question for African researchers should not be whether they have the capacity to conduct the research, but how quickly they can begin.
That is the gap a new five-year research initiative, Advancing Clinical Trials and Epidemic Preparedness Research Capacity in Africa (ACT-PREP), is seeking to address.
The project will be officially launched in Uganda on September 28th, 2026, bringing together researchers and partners from universities and research institutions across Africa and Europe. The launch will be held at the Makerere University School of Public Health (MakSPH) Auditorium in Kampala.
Led by Makerere University School of Public Health, ACT-PREP is designed to strengthen Africa’s ability to conduct clinical trials and other research before and during infectious disease outbreaks.
Africa has repeatedly faced epidemics of diseases such as Marburg, Ebola, COVID-19 and other emerging infections. Yet when outbreaks occur, the capacity to quickly generate the evidence needed to guide treatment, prevention and public health decisions remains underdeveloped.
ACT-PREP aims to make research part of outbreak preparedness not something that begins only after an epidemic has already spread.
According to Prof Rhoda Wanyenze, the Principal Investigator on the project, “the initiative will establish a framework for more equitable collaboration among 10 African and two European institutions, working alongside Universities and the Africa Centres for Disease Control and Prevention (Africa CDC)”.
The consortium includes institutions from Uganda, Rwanda, Tanzania, the Democratic Republic of Congo, Somalia, South Sudan and Senegal, as well as European partners in Sweden and Germany. Africa CDC is also among the participating institutions.
For Uganda, the launch at Makerere University is significant. The university is taking the scientific lead on a programme that places African research institutions at the centre of efforts to prepare for future epidemics.
One of ACT-PREP’s central ambitions is to address the shortage of researchers and systems capable of rapidly conducting high-quality clinical research during emergencies.
The project will strengthen clinical research, ethics and regulatory capacity, while also supporting laboratory and disease surveillance systems. It will integrate training into PhD and postdoctoral programmes, with the consortium aiming to train at least 700 fellows at the end of the project.
“The idea is straightforward: Africa needs not only laboratories and equipment, but also people with the skills to use them when an outbreak begins” – Says Dr Steven Kabwama, ACT-PREP Project Manager.
Researchers will also be supported to share expertise, data, resources and technology across institutions and national borders.
ACT-PREP will further explore One Health approaches and artificial intelligence-supported systems to improve disease prediction, detection and rapid response. The project also seeks to support more streamlined regulatory processes so that clinical trials can be deployed and monitored more quickly when they are needed.
The experience of recent epidemics has shown that time is one of the most valuable resources in an outbreak.
Delays in detecting a pathogen, setting up research sites, securing ethical and regulatory approvals or generating reliable evidence can affect how quickly health authorities are able to respond.
ACT-PREP is built around the idea that many of these systems should already be in place before the next emergency.
That means having trained researchers, functioning laboratories, established regulatory pathways, surveillance systems and relationships between institutions that can be activated when an outbreak occurs.
It also means changing how research partnerships are built.
Rather than relying on external institutions to arrive when a crisis begins, the project seeks to strengthen African institutions themselves and create longer-term collaborations in which expertise, technology, data and resources can be shared across borders.
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