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Mak 70th Grad PhD Citations Session 1, Part 3

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College of Health Sciences (CHS)

 

BBOSA Nicholas

A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda

Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.

 

BWIRE Godfrey

Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.

Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).

 

EGESA Moses

Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens

Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.

 

KADDUMUKASA Martin

Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda

Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.

 

KAYIMA James

Hypertension in Uganda: epidemiology and association with HIV infection and genetics

Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.

 

MBOOWA Gerald

Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana

Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.

 

MPIMBAZA Arthur Mwambari

Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda

Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.

 

NABATANZI Rose (Ms)

Innate immune system recovery after long-term antiretroviral therapy in an African cohort

Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.

 

NAJJUKA Christine Florence (Ms)

Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda

Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.

 

ZIDA Andre

Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system

Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.

 

Please click the links below to navigate to the PhD Citations for the respective Sessions.

< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >

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Mark Wamai

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Makerere Urges New Scholarship Beneficiaries to Prioritise Academics and Personal Safety

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Makerere University has urged female students admitted under the Makerere University Council Tuition and Functional Fees Waiver Scholarship for the 2026/27 academic year to take the opportunity seriously, focus on their academic performance, and stay alert about their personal safety.

The message was delivered during an orientation for the scholarship beneficiaries at the Senate Conference Hall, where officials from the Gender Mainstreaming Directorate welcomed the students and shared guidance on academic success, security, mentorship, and responsible social conduct.

The Chief Gender Mainstreaming Officer cautions students on safety and self-reliance

Dr. Euzobia Mugisha Baine, Chief Gender Mainstreaming Officer, congratulated the students on receiving the scholarship and urged them not to take it for granted.

She advised them to seek information from the relevant university offices instead of relying on assumptions or what fellow students tell them, and to keep records of official communication whenever they raise concerns or follow up on university matters.

Dr. Euzobia, Chief Gender Mainstreaming Officer, giving her remarks

Dr. Baine said students should take responsibility for their own security, warning them not to trust strangers easily and urging them to be careful about where they go and who they interact with.

She also reminded them that strong academic performance is required to keep the scholarship, and encouraged them to ask for help early whenever they face academic, social, or other challenges instead of waiting until the situation becomes harder to manage.

Students urged to aim for first-class results

The officers welcomed the students and encouraged them to put their studies first, urging them to aim for first-class academic results during their time at Makerere.

They advised them to use the academic support available to them, including help from course mates and any tutorials or mentoring offered within their colleges, and not to hesitate to seek assistance when they have concerns about their results or coursework.

The GMD team also spoke to scholars about personal safety, cautioning students against accepting help from strangers, including with luggage or transport, and referred to a recent incident in which a student’s belongings were stolen. She urged them to stay alert as they settled into university life.

Focus on academic foundations and safe social conduct

Other speakers, including Ms. Susan Mbabazi, who is the Principal Gender Officer, Ms. Abilat Lozirah, and Cynthia Ayaa Kamaketch emphasised the need to build a strong academic foundation from the start of the semester. They encouraged students to attend lectures regularly, read beyond classroom notes, use university resources such as internet access and the library, and develop steady study habits instead of waiting until exams are near.

A section of female students awarded the Makerere University Council Tuition and Functional Fees Waiver Scholarship for the 2026/27 academic year listening to Mr. Eric Tumwesigye, the Principal Gender Officer and Head of the Students Affairs Division during their orientation at the Senate Conference Hall.

They also warned students to be careful when meeting people they do not know well, advising them to hold academic discussions and social meetings in open, public spaces such as Freedom Square rather than in private rooms.

The students were also encouraged to seek mentorship from university staff and others who could guide them in their academic and career development, and to identify a mentor before leaving the orientation.

The orientation also pointed students to key university services and locations they should know, including the university health facilities, the Makerere Police Post, the Counselling and Guidance Centre, and places of worship on campus.

Speakers reminded the students that the scholarship gives them a chance to pursue their education at Makerere University, and that keeping it depends on their discipline, academic performance, and willingness to seek support when needed.

Allan Ainematsiko

My name is Ainematsiko Allan. I am a student of Makerere University and currently in my final year. I am pursuing a Bachelors in Journalism and Communication.

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AR Department Bids Farewell to Mr. Ssentongo and Ms. Akoli

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Mr. Charles Ssentongo (C) and Ms. Betty Akoli (3rd R) are joined by Staff and Family to cut cake at the farewell luncheon on 18th September 2026. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.

By Gerald Ochwo

On Friday 18th September 2026, the Department of the Academic Registrar, Makerere University, held a befitting farewell ceremony in honour of Mr. Charles Ssentongo and Ms. Betty Akoli, who have retired from University service upon attaining the mandatory retirement age of 60 years.

Mr. Ssentongo retires as Deputy Academic Registrar in charge of Undergraduate Admissions and Records, after 26 years of dedicated service to the University, a journey he began in 2000. Ms. Akoli retires as Assistant Academic Registrar.

Ms. Prossie Nakayiki (L) poses with Mr. Ssentongo (C) and Ms. Akoli (R) shortly after presenting them with their plaques. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Ms. Prossie Nakayiki (L) poses with Mr. Ssentongo (C) and Ms. Akoli (R) shortly after presenting them with their plaques.

The farewell, held in the Senate Building Conference Hall, was presided over by Ms. Prossie Nakayiki, the Acting Academic Registrar, and was attended by members of the Senior Management Team and staff of the Academic Registrar’s Department.

In recognition of their distinguished and spotless service, the two retirees were awarded institutional plaques and assorted gifts from the Department and individual members of staff.

Mr. Ssentongo and Ms. Akoli receive gifts from staff of their former Units including Mr. Justus Karegyeya (2nd L) the Ag. Deputy Academic Registrar, Undergraduate Admissions and Records. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Mr. Ssentongo and Ms. Akoli receive gifts from staff of their former Units including Mr. Justus Karegyeya (2nd L) the Ag. Deputy Academic Registrar, Undergraduate Admissions and Records.

Mr. Ssentongo and Ms. Akoli’s retirement follows that of other senior members of the Department, including Mrs. Patience Mushengyezi, who retired earlier this year.

The Department of the Academic Registrar remains deeply indebted to Mr. Ssentongo and Ms. Akoli for their highly committed, exemplary, and dedicated service to Makerere University. We wish them a happy, healthy, and fulfilling retirement.

Ms. Betty Akoli receives a gift from a former colleague. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Ms. Betty Akoli receives a gift from a former colleague.

We celebrate you.

More photos from the event: https://flic.kr/s/aHBqjD5btz

Mak Editor

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Prof. Sarah Ssali shares institutional best practices ahead of The Trust Summit

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Prof. Sarah Ssali, Panelist, Virtual Round Table on Restoring Trust in Academia and the Knowledge Economy, September 15, 2026. Graphic: X/@GTSummit2026

Prof. Sarah Ssali the First Deputy Vice Chancellor in charge of Academic Affairs (DVCAA) at Makerere University was one of the panelists that addressed the complex challenges facing African higher education during a Virtual Round Table on Restoring Trust in Academia and the Knowledge Economy held September 15, 2026. The event was organised by Strathmore University as part of the pre-summit events for The Trust Summit (TTS), due to be held in Nairobi, Kenya from October 21-23, 2026.

She was also welcomed in her capacity as the Director of the African Research Universities Alliance (ARUA) Centre of Excellence in Notions of Identity, a platform she used to deliver warm regards from the Vice Chancellor, Prof. Barnabas Nawangwe. Other panelists included; Dr. Vincent Ogutu-Vice Chancellor, Strathmore University and Prof. Gilbert Kokwaro-Director, Institute of Healthcare Management, Strathmore University Business School, while the Moderator was Dr. Maureen Syallow-Senior Lecturer, Strathmore University.

In her submission, Prof. Ssali emphasised the need to understand that universities are working in a turbulent times, and do not deserve to be at the receiving end of some of the challenges being ascribed to them. She added that challenges affecting society ought to be handled in partnership with other stakeholders and key players.

An example of this kind of criticism is on the question on the quality and integrity of degrees that has come up severally and is being fueled by the fact that not many graduates can find gainful employment after completing university.

“We have many more people living longer, getting educated, and chasing fewer jobs. For example, in the case of Uganda, we graduate around 40,000 students per year, but only 700 jobs are being created in the public sector per year” she noted.

Turning to the need to maintain standards and trust, Prof. Ssali outlined the rigorous systems already in place. These include holistic curriculum development involving stakeholders such as the National Council of Higher Education, Government Ministries, and the National Planning Authority.

Prof. Ssali also highlighted the importance of quality assurance, international benchmarking, and constant evaluations. She nevertheless conceded that despite having all these efforts in place, universities still face immense pressure from ranking systems and the need to prove their worth.

Reflecting on the historical debate regarding the role of an African university, she contrasted the school of thought advocating for global competitiveness with that emphasising practical relevance to local development challenges, concluding that taking the middle path; globally competitive and locally relevant, remains the viable option.

Addressing the issue of trust directly, Prof. Ssali noted that universities, just like the aviation and healthcare industries, are more concerned with what systems are in place to correct any errors should they arise.

She explained that just as one plane crash does not shut down the aviation industry, a single failure in a university does not warrant shutting it down. Instead, the focus should be on checking the black box, correcting errors, and improving standards to ensure the institution continues to serve its purpose.

Elvis Lubanga, Makerere University, Kampala Uganda, East Africa.
Elvis Lubanga

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