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Mak 70th Grad PhD Citations Session 1, Part 3

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College of Health Sciences (CHS)

 

BBOSA Nicholas

A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda

Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.

 

BWIRE Godfrey

Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.

Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).

 

EGESA Moses

Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens

Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.

 

KADDUMUKASA Martin

Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda

Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.

 

KAYIMA James

Hypertension in Uganda: epidemiology and association with HIV infection and genetics

Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.

 

MBOOWA Gerald

Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana

Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.

 

MPIMBAZA Arthur Mwambari

Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda

Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.

 

NABATANZI Rose (Ms)

Innate immune system recovery after long-term antiretroviral therapy in an African cohort

Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.

 

NAJJUKA Christine Florence (Ms)

Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda

Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.

 

ZIDA Andre

Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system

Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.

 

Please click the links below to navigate to the PhD Citations for the respective Sessions.

< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >

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Mark Wamai

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AR Department Bids Farewell to Mr. Ssentongo and Ms. Akoli

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Mr. Charles Ssentongo (C) and Ms. Betty Akoli (3rd R) are joined by Staff and Family to cut cake at the farewell luncheon on 18th September 2026. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.

By Gerald Ochwo

On Friday 18th September 2026, the Department of the Academic Registrar, Makerere University, held a befitting farewell ceremony in honour of Mr. Charles Ssentongo and Ms. Betty Akoli, who have retired from University service upon attaining the mandatory retirement age of 60 years.

Mr. Ssentongo retires as Deputy Academic Registrar in charge of Undergraduate Admissions and Records, after 26 years of dedicated service to the University, a journey he began in 2000. Ms. Akoli retires as Assistant Academic Registrar.

Ms. Prossie Nakayiki (L) poses with Mr. Ssentongo (C) and Ms. Akoli (R) shortly after presenting them with their plaques. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Ms. Prossie Nakayiki (L) poses with Mr. Ssentongo (C) and Ms. Akoli (R) shortly after presenting them with their plaques.

The farewell, held in the Senate Building Conference Hall, was presided over by Ms. Prossie Nakayiki, the Acting Academic Registrar, and was attended by members of the Senior Management Team and staff of the Academic Registrar’s Department.

In recognition of their distinguished and spotless service, the two retirees were awarded institutional plaques and assorted gifts from the Department and individual members of staff.

Mr. Ssentongo and Ms. Akoli receive gifts from staff of their former Units including Mr. Justus Karegyeya (2nd L) the Ag. Deputy Academic Registrar, Undergraduate Admissions and Records. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Mr. Ssentongo and Ms. Akoli receive gifts from staff of their former Units including Mr. Justus Karegyeya (2nd L) the Ag. Deputy Academic Registrar, Undergraduate Admissions and Records.

Mr. Ssentongo and Ms. Akoli’s retirement follows that of other senior members of the Department, including Mrs. Patience Mushengyezi, who retired earlier this year.

The Department of the Academic Registrar remains deeply indebted to Mr. Ssentongo and Ms. Akoli for their highly committed, exemplary, and dedicated service to Makerere University. We wish them a happy, healthy, and fulfilling retirement.

Ms. Betty Akoli receives a gift from a former colleague. Farewell Luncheon held by Department of Academic Registrar in honour of Mr. Charles Ssentongo, Deputy Academic Registrar – Undergraduate Admissions and Records and Ms. Betty Akoli, Assistant Academic Registrar presided over by Ag. Academic Registrar Ms. Prossie Nakayiki, 18th September 2026, Senate Conference Hal, Level 4, Senate Building, Makerere University, Kampala Uganda, East Africa.
Ms. Betty Akoli receives a gift from a former colleague.

We celebrate you.

More photos from the event: https://flic.kr/s/aHBqjD5btz

Mak Editor

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Prof. Sarah Ssali shares institutional best practices ahead of The Trust Summit

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Prof. Sarah Ssali, Panelist, Virtual Round Table on Restoring Trust in Academia and the Knowledge Economy, September 15, 2026. Graphic: X/@GTSummit2026

Prof. Sarah Ssali the First Deputy Vice Chancellor in charge of Academic Affairs (DVCAA) at Makerere University was one of the panelists that addressed the complex challenges facing African higher education during a Virtual Round Table on Restoring Trust in Academia and the Knowledge Economy held September 15, 2026. The event was organised by Strathmore University as part of the pre-summit events for The Trust Summit (TTS), due to be held in Nairobi, Kenya from October 21-23, 2026.

She was also welcomed in her capacity as the Director of the African Research Universities Alliance (ARUA) Centre of Excellence in Notions of Identity, a platform she used to deliver warm regards from the Vice Chancellor, Prof. Barnabas Nawangwe. Other panelists included; Dr. Vincent Ogutu-Vice Chancellor, Strathmore University and Prof. Gilbert Kokwaro-Director, Institute of Healthcare Management, Strathmore University Business School, while the Moderator was Dr. Maureen Syallow-Senior Lecturer, Strathmore University.

In her submission, Prof. Ssali emphasised the need to understand that universities are working in a turbulent times, and do not deserve to be at the receiving end of some of the challenges being ascribed to them. She added that challenges affecting society ought to be handled in partnership with other stakeholders and key players.

An example of this kind of criticism is on the question on the quality and integrity of degrees that has come up severally and is being fueled by the fact that not many graduates can find gainful employment after completing university.

“We have many more people living longer, getting educated, and chasing fewer jobs. For example, in the case of Uganda, we graduate around 40,000 students per year, but only 700 jobs are being created in the public sector per year” she noted.

Turning to the need to maintain standards and trust, Prof. Ssali outlined the rigorous systems already in place. These include holistic curriculum development involving stakeholders such as the National Council of Higher Education, Government Ministries, and the National Planning Authority.

Prof. Ssali also highlighted the importance of quality assurance, international benchmarking, and constant evaluations. She nevertheless conceded that despite having all these efforts in place, universities still face immense pressure from ranking systems and the need to prove their worth.

Reflecting on the historical debate regarding the role of an African university, she contrasted the school of thought advocating for global competitiveness with that emphasising practical relevance to local development challenges, concluding that taking the middle path; globally competitive and locally relevant, remains the viable option.

Addressing the issue of trust directly, Prof. Ssali noted that universities, just like the aviation and healthcare industries, are more concerned with what systems are in place to correct any errors should they arise.

She explained that just as one plane crash does not shut down the aviation industry, a single failure in a university does not warrant shutting it down. Instead, the focus should be on checking the black box, correcting errors, and improving standards to ensure the institution continues to serve its purpose.

Elvis Lubanga, Makerere University, Kampala Uganda, East Africa.
Elvis Lubanga

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“We are moving in the right direction” Prof Nawangwe to Press

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Seated: Prof. Barnabas Nawangwe (C) flanked by Prof. Sarah Ssali (2nd L) and Prof. Moses Musinguzi (2nd R), Members of Management and other officials (Seated and Standing) at the Press Conference on 15th September 2026. Vice Chancellor's Press Conference, VC's Boardroom, Main Building, Kampala Uganda, East Africa.

Addressing members of the Media at the Vice Chancellor (VC)’s September 15, 2026 Press Conference, Prof. Barnabas Nawangwe shared that Makerere University rose 295 places moving from 1,071st in 2025 to 776th in the July 2026 Webometrics Ranking of World Universities. This is a noteworthy improvement on a global scale and on continental level, where the university moved from 13th place earlier this year to 11th.

Still in the right direction, the number of graduate students completing their studies at Makerere has nearly doubled over the past five years as the University steps up efforts to improve training and research output. The completion rates have increased from 1,588 in 2023 to 1,874 in 2024, 2199 in 2025 and 2,922 in 2026.

The Vice Chancellor attributed this growth partly to government funding and digital systems that have been set up to track student progress.

Improving the Academic Environment

In alignment with VC, the First Deputy Vice Chancellor in charge of Academic Affairs (DVCAA), Prof. Sarah Ssali assured the media that a number of quality assurance measures have been put in place to improve the university’s core functions. These range from assessment forms that enable students to evaluate their courses and provide feedback that can be used to improve teaching and learning as well as research environments.

In line with digitalisation of University processes, Prof. Ssali noted that the Academic Management Information System (ACMIS) enables supervisors, colleges and University Management to identify delays in student progress and take corrective action.

The system currently empowers students to track their academic progress and print their own testimonials, and in future, transcripts, without having to queue up. These services are accessible by students who have fulfilled their tuition obligations.

Infrastructure Development

The Acting Second Deputy Vice Chancellor in charge of Finance and Administration (DVC F&A) and Principal, College of Engineering, Design, Art and Technology (CEDAT), Prof. Moses Musinguzi, shared that the university has undertaken extensive infrastructure expansion and renovation projects, with funding from government, philanthropists and donors.

“One of the infrastructures being the building that is going to house the graduate school, among others” he elaborated.

Research News – FLOWERS Project

Makerere University prides itself as a thought leader in knowledge generation for societal transformation and development. Makerere researchers and partners have launched the FLOWERS Project — Facilitating Local Organic Waste Exchange for Regenerative Systems. Led locally by Assoc. Prof. Charles B. Niwagaba, the two-year project (2026–2028) aims to turn restaurant food waste in Kampala into animal feed and organic fertiliser. Project Kick-off Meeting: https://news.mak.ac.ug/2026/09/makerere-partners-kick-off-flowers-project-to-turn-restaurant-waste-into-a-regenerative-resource/

Upcoming Events highlighted

Makerere Marathon
The sixth edition of the Makerere University Marathon will take place on Sunday, 27 September 2026, starting and finishing at Freedom Square. Marathon kits are available at UGX 50,000 and can be purchased online via https://shorturl.at/Vjovo

The Annual Makerere Guild Medical Camp
The camp will be held from 17th to 18th September 2026, starting at 8:00 a.m. to 5:00 p.m., in the Freedom Square. The Camp is organised by Guild leadership under the Office of the Dean of Students. Link: https://events.mak.ac.ug/events/2026/09/17/816

The Press Conference was graced by Members of Management, Staff and the media fraternity who were all appreciated for their contribution informing the public about developments at Makerere. This press briefing is part of the media engagements organised by the university Public Relations Office aimed at fostering open communication lines with the public through the media. It happens every two months with the previous one having taken place on 15th July 2026.

Please see Downloads for the Press Statement and its supporting documents.

Photography by Benite Uwase, Public Relations Office, Makerere University

Elvis Lubanga, Makerere University, Kampala Uganda, East Africa.
Elvis Lubanga

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