General

Mak 70th Grad PhD Citations Session 1, Part 3

Published

5 years ago

January 17, 2020

Mark Wamai

The Chancellor-Prof. Ezra Suruma (Right) hands over the PhD Cylinder to CHS' Dr. Najjuka Christine Florence during Day 1 of the 70th Graduation Ceremony, 14th January 2020, Makerere University, Kampala Uganda.

College of Health Sciences (CHS)

BBOSA Nicholas

A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda

Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.

BWIRE Godfrey

Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.

Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC^® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).

EGESA Moses

Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens

Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.

KADDUMUKASA Martin

Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda

Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.

KAYIMA James

Hypertension in Uganda: epidemiology and association with HIV infection and genetics

Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.

MBOOWA Gerald

Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana

Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.

MPIMBAZA Arthur Mwambari

Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda

Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.

NABATANZI Rose (Ms)

Innate immune system recovery after long-term antiretroviral therapy in an African cohort

Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.

NAJJUKA Christine Florence (Ms)

Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda

Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3^rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.

ZIDA Andre

Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system

Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.

Please click the links below to navigate to the PhD Citations for the respective Sessions.

< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >

#Mak70thGrad

General

Applications for Admission to Undergraduate Programmes 2025/26 AY

Published

2 days ago

April 17, 2025

Mak Editor

The Academic Registrar, Makerere University invites applications from Ugandan, East African, and international applicants for the undergraduate programmes under the private sponsorship scheme for the 2025/2026 Academic Year for ‘A’ Level Leavers Only.

Each applicant should:

Have the Uganda Certificate of Education (UCE) with at least five (5) passes, or its equivalent and at least two (2) principal passes at Uganda Advanced Certificate of Education (UACE) obtained at the same sitting. For day programmes only candidates who sat A’ Level in 2024, 2023 and 2022 are eligible to apply. For evening, afternoon, and external programmes, a candidate is not restricted on the year of sitting A’ Level. Detailed information on the weighting system can be accessed by following this link.

Other relevant information can be obtained from UNDERGRADUATE ADMISSIONS OFFICE, LEVEL 3, SENATE BUILDING OR CAN BE found on the University Website https://www.mak.ac.ug. Effective Wednesday 16^th April 2025.

A non-refundable application fee of shs.50,000/= for Ugandans, East African and S. Sudan applicants or $75 or equivalent for internationals plus bank charges should be paid in any of the banks used by Uganda Revenue Authority.

Candidates who hold grades X, Y, Z, 7 and 9 of ‘O’Level results should not apply because they are not eligible for admission. Below are the availble courses including respective fees structure.

Advert-Mak-PRIVATE-Undergraduate-ADMISSION-2025-2026 Download

How to submit your application

Applicants should access the Institution’s Admissions URL https://apply.mak.ac.ug/
Sign up by clicking on the REGISTER NOW. Use your full name, e-mail and Mobile No. Please note that your name must be similar to the one on your supporting academic documents for your application to be considered valid.
A password will be sent to you on your mobile phone and email.
The system will prompt you to change the password to the one you can easily remember.
To fill an application form, click on the APPLY NOW button displayed on the appropriate running scheme.
Obtain a payment reference number by clicking on “Pay for Form” Button
Make a payment at any of the banks used by Uganda Revenue Authority

MOBILE MONEY PAYMENT STEPS:

Dial *272*6# on either MTN or Airtel
Select option 3-Admission
Select option 3-Pay Fees
Enter reference number obtained from Application portal
Details of Application form will be confirmed
Enter PIN to confirm payment

The closing date for receiving applications to undergraduate programmes shall be Tuesday 20^th May 2025.

WARNING:

Applicants are strongly warned against presenting forged or other people’s academic documents to support their applications for admission. The consequences, if discovered, are very grave indeed.
Do not buy any other documents not originating from the Academic Registrar’s Office. Those who buy them do so at their own risk.
The Academic Registrar has not appointed any agent to act on his behalf to solicit for additional funds other than the application fee stated above.
Applicants are advised to use the right programme names and codes. the university will not be responsible for any wrong information entered in the system by applicants.

Prof. Buyinza Mukadasi
ACADEMIC REGISTRAR

General

Embrace the Safeguarding Policy- Makerere Jinja Campus Students urged

Published

3 days ago

April 15, 2025

Carol Kasujja Adii

Makerere University Jinja Campus safeguarding policy sensitization meeting for students, staff and stakeholders by the Office of the Dean of Students, 15th April 2025 at the Civil Service College, Jinja, Uganda, East Africa.

The Director of Makerere University Jinja Campus, Associate Professor Ronald Kakungulu-Mayambala, has urged students to familiarise themselves with the Safeguarding policy aimed at creating a safer and more inclusive learning environment.

Speaking during the safeguarding policy sensitization meeting held today Tuesday, April 15, 2025 at the Civil Service College, Jinja, Prof. Kakungulu-Mayambala, emphasized the importance of awareness and adherence to the policy, which seeks to protect students, staff, and other stakeholders from all forms of abuse, harassment, exploitation, and discrimination.

“As Management we want every student to enjoy their stay at the University without being tormented and that can only happen, if students know their rights by reading about different policies on our website. You are meant to be living in a safe environment. We do not want anybody’s dream to be shattered or somebody to drop out from University,” Prof. Kakungulu-Mayambala, said.

Prof. Ronald Kakungulu-Mayambala, the Director Makerere University Jinja Campus. Makerere University Jinja Campus safeguarding policy sensitization meeting for students, staff and stakeholders by the Office of the Dean of Students, 15th April 2025 at the Civil Service College, Jinja, Uganda, East Africa. — ***Prof. Ronald Kakungulu-Mayambala, the Director Makerere University Jinja Campus.***

In his speech, Prof. Kakungulu-Mayambala, also called upon students who have complaints but do not know the reporting lines, to approach staff safeguarding champions to make sure that they live in a safe environment.

Addressing guests, Emmanuel Muchake, the Guild Administrator at Jinja Campus, pointed out that the launch of the safeguarding policy is timely because as a University, without creating a conducive environment for teaching and learning, they will not have students graduate.

On Friday, April 4,2025, the Third Deputy Prime Minister and Minister without Portfolio, Right Honourable Lukia Isanga Nakadama, officially launched the Safeguarding Policy and commended Makerere University for crafting a policy that lays out the University’s framework for embedding viable safeguarding measures into its ethos and all institutional activities and processes to: Identify, detect, and act swiftly on safeguarding risks.

The Safeguarding Policy was developed in response to the growing need for institutions of higher learning to implement proactive measures that address concerns related to student welfare, mental health, gender-based violence, and power imbalances in academic settings.

Mr. Emmanuel Muchake addressing guests. Makerere University Jinja Campus safeguarding policy sensitization meeting for students, staff and stakeholders by the Office of the Dean of Students, 15th April 2025 at the Civil Service College, Jinja, Uganda, East Africa. — ***Mr. Emmanuel Muchake addressing guests.***

Some of potential safeguarding risks in Institutions of higher learning include emotional distress, Sexual Exploitation, Abuse and Harassment (SEAH); material loss, financial exploitation, discrimination and neglect, unfair and illegitimate response to civic engagements, cyber security/threats, psychological and emotional harm, substance abuse and physical assault. Discrimination and neglect which are often high risks for students with disabilities and international students.

The safeguarding policy sensitization meeting in Jinja Campus brought together students and staff in a meaningful dialogue on safeguarding issues affecting learning.

The event was graced by Dr. Rodney Rugyema, from the Dean of Students Office, who emphasized the University’s commitment to the well-being of all its members. In his remarks, he highlighted the importance of safeguarding policies in preventing abuse, harassment, exploitation, and other forms of misconduct within the Jinja Campus community.

“Safeguarding is not a one-time action, but a continuous culture of care and accountability. We all have a role to play in ensuring a safe and respectful space for learning and growth,” Dr Rugyema, said.

Dr. Rodney Rugyema (Left) and Prof. Ronald Kakungulu-Mayambala (Right) during the sensitization. Makerere University Jinja Campus safeguarding policy sensitization meeting for students, staff and stakeholders by the Office of the Dean of Students, 15th April 2025 at the Civil Service College, Jinja, Uganda, East Africa. — ***Dr. Rodney Rugyema (Left) and Prof. Ronald Kakungulu-Mayambala (Right) during the sensitization.***

The sensitization session covered key topics including; recognizing signs of abuse, understanding reporting procedures on the MakSafeSpace and fostering mutual respect among peers.

Participants were encouraged to actively engage and reflect on their roles in upholding safety standards both on and off campus.

Students who attended the sensitization welcomed the initiative, with many expressing optimism that the policy would improve campus safety and encourage victims to come forward without fear of retaliation.

“We have seen issues go unreported in the past because students didn’t know where to turn. This policy provides clarity and assurance that the university is taking these matters seriously,” noted, a third-year student.

The University plans to conduct a series of sensitization workshops and distribute printed copies of the policy to ensure that every member of the campus community is well-informed. This initiative is part of Makerere University‘s broader strategy to reinforce its values of integrity, respect, and protection for all.

The Safeguarding Sensitization Meeting concluded with a collective pledge to uphold safety, dignity, and mutual respect within the University community.