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Mak 70th Grad PhD Citations Session 1, Part 3

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College of Health Sciences (CHS)

 

BBOSA Nicholas

A molecular phylogenetic and modelling approach towards understanding the transmission dynamics and genetic diversity of HIV-1 in the fishing communities of Lake Victoria, Uganda

Dr. BBOSA Nicholas used molecular phylogenetic and modelling approaches to dissect the transmission dynamics of HIV in the fishing communities of Lake Victoria. The fishing communities are disproportionately affected by HIV relative to the general population and for a long time, the dynamics of HIV transmission were not well understood. His research revealed for the first time in Uganda that the fishing communities were a sink for HIV transmission from the general population and negated the generally held assumption of the fishing communities being viral reservoirs. The findings have contributed towards informing public health policies on the implementation of targeted interventions for effective HIV epidemic control in most at-risk populations. This study was funded by the UK Medical research council, and was supervised by Prof. Pontiano Kaleebu, Prof. Andrew Leigh-Brown, Dr. Bernard S. Bagaya, Assoc. Prof Noah Kiwanuka and Dr. Rebecca N. Nsubuga.

 

BWIRE Godfrey

Molecular characterization and rapid detection of Vibrio cholerae in Uganda: the relationship between human pathogens and aquatic environment.

Dr. BWIRE Godfrey studied Vibrio cholerae, the bacteria responsible for repeated cholera outbreaks in Uganda to determine their genetic profile, spread, transmission, virulence, aquatic environmental reservoirs and a field cholera rapid diagnostic test (RDT). The study found that cholera outbreaks in Uganda were due to three genetically related V. cholerae clones. The clones showed transmission within Uganda, East and Central African regions. The surface water sources in Uganda were possibly not reservoirs for the epidemic V. cholerae. The accuracy of the cholera RDT, a modified Crystal VC® dipsticks was high. This study enhances our understanding of cholera outbreaks and may help in prevention, control and elimination of cholera in Uganda. The study was jointly funded by the Uganda Ministry of Health and Bill and Melinda Gates Foundation (USA) and supervised by Prof. Christopher Garimoi Orach (MakSPH) and Prof. David Allen Sack (John Hopkins University, USA).

 

EGESA Moses

Human B and T cell responses to novel Schistosoma mansoni skin-stage antigens

Mr. EGESA Moses studied human immune responses to parasite components expressed at the vulnerable skin larva stage of the human blood fluke, Schistosoma. It was not known how endemic populations respond to recombinant components of the larvae and how these immune responses relate with intensity of infection when people get re-infected. The recombinant antigens induced inflammatory cytokine responses. Additionally, antibodies to these antigens were detectable and were affected by treatment. Although not associated with reinfection intensity, the information generated informs the selection and prioritization of vaccine targets. This study was funded by a Wellcome Trust Strategic Award and the DELTAS Africa Initiative and supported by European Commission’s Seventh Framework Programme, and was supervised by Dr. Bernard Bagaya, Prof. Maria Yazdanbakhsh and Dr. Stephen Cose.

 

KADDUMUKASA Martin

Sodium intake in post-stroke patients – its influence on blood pressure, knowledge and perceptions and stroke outcomes in Uganda

Dr. KADDUMUKASA Martin’s thesis focuses on salt intake and cardiovascular stroke. He estimates the daily intake and its association with blood pressure and stroke. He further investigates knowledge, perceptions, and consumption decisions after stroke. He uses 24-hour urine to determine the salt intake in stroke patients. He notes that stroke survivors with high blood pressure have twice the levels of salt compared to stroke survivors without blood pressure. Poor knowledge, perceptions, and salt use beliefs. Finally, a high frequency of stroke recurrence and death was observed in this group. This study recommends primary stroke prevention through salt intake reduction and population salt awareness through education. This study was supported by NIH MEPI-linked Neurology Award (No. 5R24TW008886), Fogarty International Centre and was supervised by Prof. E. Katabira, Prof. Martha Sajatovic, Prof. Larry Goldstein and Dr. Pundik.

 

KAYIMA James

Hypertension in Uganda: epidemiology and association with HIV infection and genetics

Dr. KAYIMA James investigated the association of HIV infection and selected genes with blood pressure traits among Ugandans. He observed that, unlike the western populations, the frequency of hypertension was lower among HIV-infected compared to uninfected subjects in Uganda. Further, he uncovered the profound negative effect of SUB/NPR3 gene on systolic blood pressure. These finding suggest a protective effect of HIV on hypertension; and a potential modifying effect of SUB/NPR3 gene on hypertension in African populations. This work elucidates the role of HIV and population-specific genetic factors in the control of hypertension risk. It builds a foundation for formulation of prevention efforts for cardiovascular disease among high-risk groups; and for pharmacogenetic studies to identify appropriate medication for hypertensive black populations. This study was funded by Medical Education Partnership Initiative on Cardiovascular Disease (MEPI-CVD), and was supervised by Dr. Achilles Katamba, Prof. Harriet Mayanja Kizza, Prof. Xiaofeng Zhu and Prof. Mahboob Rahman.

 

MBOOWA Gerald

Functional host-genetic loci associated with pediatric HIV-disease progression in Uganda and Botswana

Dr. MBOOWA Gerald used genomics and bioinformatics approaches to identify a set of genes that informs us which person if HIV-infected will take many years to develop AIDS (symptoms) without HIV-treatment. His research revealed that following HIV infection, there are two groups of people; Rapid-AIDS progressors (develop symptoms in 3-years or less after infection) and Long-term non-progressors (>10-years to develop symptoms) without HIV-treatment. These findings have implications for the current “Test-and-Treat and Treat-for-Life” HIV-treatment policy; when one tests HIV-positive and started on treatment-for-life exposing them to drugs’ dangerous side-effects yet some HIV-infected people have nature ability to stay for many years without developing symptoms in absence of HIV-treatment. This study was funded by the Collaborative African Genomics Network-(CAfGEN) and Training Health Researchers into Vocational Excellence in East Africa-(THRiVE-2), and supervised by Prof Moses Joloba and Dr. David Kateete.

 

MPIMBAZA Arthur Mwambari

Determinants of severe malaria among children hospitalised at Jinja Regional Referral Hospital, Uganda

Dr. MPIMBAZA Arthur Mwambari studied determinants of severe malaria among children in the Busoga sub-region. Risk factors for severe malaria included delayed care seeking by more than 24 hours after fever onset and seeking care at a drug shop as the initial response. For convenience, drug shops were the most common provider sought by caregivers of children with severe malaria. However, drug shops offered sub-optimal healthcare services compared to public health facilities. Hemoglobin S heterozygotes, alpha thalassemia heterozygosity and homozygosity were associated with protection against severe malaria. Drug shops were a problem, contributing to delay and severe malaria. The role of drug shops in caring for children with malaria needs to be re-evaluated and services at public health facilities strengthened. This study was funded by NIH Fogarty International Center (TW009343 and TW007375) and was supervised by Assoc. Prof. Charles Karamagi, Prof. Anne Katahoire, Grace Ndeezi and Philip J Rosenthal.

 

NABATANZI Rose (Ms)

Innate immune system recovery after long-term antiretroviral therapy in an African cohort

Dr. NABATANZI Rose studied whether key blood cell populations of HIV infected adults recover completely after at least seven years of treatment with antiretroviral therapy (ART). This research found that despite at least seven years of effective ART, key first line defence cells among HIV-infected individuals were still fewer and produced low chemical mediators of first line defence against invading germs; compared with age-matched healthy HIV uninfected individuals. More emphasis should be put on ways of improving the body’s defence system for individuals on long-term ART to levels comparable to HIV-uninfected individuals, to prevent or delay HIV-associated complications among adults aging with the disease. This study was funded by DELTAS Africa Initiative, the Wellcome Trust and UK government and Alliance for Global Health and Science at University of California, Berkeley, USA; and was supervised by Prof. Damalie Nakanjako, Prof. Moses Joloba, Prof. Stephen Cose and Prof. Sarah Rowland Jones.

 

NAJJUKA Christine Florence (Ms)

Characterisation of extended spectrum Beta lactamases elaborated in Enterobactereaceae in Uganda

Dr. NAJJUKA Christine Florence investigated the prevalence of Extended Spectrum beta-Lactamases (ESBLs), the factors associated with gastrointestinal carriage, genotypes, transmission dynamics and co-resistance among clients attending outpatient clinics in Kampala, Kayunga and Mpigi Districts. She found predominance of cefotaximase in Kampala and presence of plasmid-mediated AmpC beta-lactamase genes, especially in ceftriaxone-susceptible Escherichia coli. Use of ciprofloxacin, inoculation and routine health follow up were risk factors, while rural residency and visiting lower health centres were protective of carriage of resistant bacteria. Transmission was predominantly by horizontal gene transfer of cefotaximase with at least two non-beta-lactam resistance genes. The findings inform widespread gut colonisation by bacteria resistant to 3rd generation cephalosporins and commonly used non beta-lactam agents, a source for transmission and infection with unpredictable and limited treatment options. This study was funded by Sida-Makerere Bilateral Research Programme and the Carnegie Cooperation of New York, and was supervised by Prof. Moses L. Joloba and Prof. Sabiha Y. Essack.

 

ZIDA Andre

Creating and institutionalizing supports for evidence-informed decision making, including a rapid response service, in the Burkina Faso health system

Dr. ZIDA Andre’s research focused on decision making in the Burkina Faso health system. His investigation focused on the institutionalization of a policy support unit called rapid response to provide evidence for urgent decision-making. The study showed that the institutionalization of decision support units demands a robust framework and political will. It can be non-linear, and it depends on the leadership of unit managers to implement relevant activities, mobilize funding, and recruit and maintain sufficient human resources. This study developed a clear roadmap for evidence-informed decision-making and policy unit institutionalization. This study was funded by International Development Research Centre (IDRC) and the European Union, and was supervised by Prof. Nelson K. Sewankambo, John N. Lavis and Dr. Bocar Kouyate.

 

Please click the links below to navigate to the PhD Citations for the respective Sessions.

< Director’s Message | Session 1: Part1 : Part2 : Part3 | Session 2 | Session 3 | Session 4 >

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Mark Wamai

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A Legacy That Still Speaks: Announcing the 2025 Emmanuel Tumusime Mutebile Annual Public Lecture

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A Legacy That Still Speaks: Announcing the 2025 Emmanuel Tumusime Mutebile Annual Public Lecture, 3rd December 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.

Inaugurated in 2022, Makerere University is proud to announce the 2025 Emmanuel Tumusime Mutebile Annual Public Lecture. On 3rd December, we will celebrate a legacy that continues to whisper its truth into the future. The legacy of Professor Emmanuel Tumusime Mutebile, a man whose life was defined by discipline, foresight, and an unwavering belief in resilient institutions. The lecture will be hosted in the Main Hall of the Main Building from 2:00 pm to 5:00 pm.

This year’s lecture will be held under the theme:

“Shaping Africa’s Future: Intergenerational Leadership, Economic Resilience & the Power of Innovation.”

This theme emerges at a defining moment for Africa. The continent stands at a crossroads, rich in an ever-growing youthful population, natural resources, and emerging technologies, yet simultaneously challenged by economic volatility, climate pressures, leadership transitions, and widening development gaps. The 2025 lecture, therefore, seeks to move beyond commemoration, positioning itself as a strategic space for reflection, recalibration, and forward-looking action.

Why This Theme Matters Now

The issue of intergenerational leadership is no longer theoretical. With over 60% of Africa’s population under the age of 25, the urgency to intentionally transfer knowledge, values, and leadership capacity from established leaders to emerging ones has become critical. Sustainable transformation depends not just on the leaders of today, but on how effectively they mentor, prepare, and empower those who will steward Africa’s future. The lecture explores how this deliberate bridging of generations can strengthen institutions, safeguard ethical governance, and ensure continuity of vision.

At the same time, Africa’s recent encounters with global economic shocks, debt vulnerabilities, currency instability, and climate-induced disruptions have underscored the necessity of economic resilience. The lecture interrogates what it truly means to build economies that do not merely survive crises but adapt, stabilize, and emerge stronger. It engages with the need for diversified economic structures, credible institutions, sound policy frameworks, and leadership that prioritises long-term stability over short-term political expediency.

Equally central to the conversation is the power of innovation, not just in technology, but in policy design, institutional reform, financial systems, and governance models. Africa’s development challenges demand solutions that are context-responsive, scalable, and future-oriented. The lecture, therefore, examines how innovation can be leveraged as a catalyst for inclusive growth, sustainable financing, industrial transformation, and improved service delivery across sectors.

A Timely Platform for Critical Dialogue

The Emmanuel Tumusime Mutebile Annual Public Lecture continues to stand as a distinguished platform convening leaders and thinkers to advance critical conversations on Africa’s future. The lecture has evolved into a platform that convenes policymakers, academics, financial actors, development practitioners, private sector leaders, and youth voices to interrogate Africa’s future through the lens of principled leadership and strategic thinking. The 2025 edition will further reinforce Makerere University’s role as a convener of thought leadership and national discourse on issues of continental significance.

This annual gathering is not simply a memorial event. It is a deliberate invitation to reflect, question, and reimagine how Africa positions itself in a rapidly evolving global landscape. By centring intergenerational leadership, resilience, and innovation, the 2025 lecture challenges participants to confront the realities of today while designing systems that will serve generations yet unborn.

As Makerere University hosts this landmark conversation, it reaffirms its commitment to producing transformative leaders, advancing knowledge, and shaping policies that respond to Africa’s present and future realities.

The 2025 Tumusiime Mutebile Annual Public Lecture will also be hosted on live stream on the Makerere University YouTube page. Link: https://youtube.com/live/e6Ld-0XYLiw?feature=share

Caroline Kainomugisha is the Communications Officer, Advancement Office, Makerere University

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16 Days of Activism Campaign Unveiled

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Heads of Diplomatic Missions are joined by Dr. Winifred Kabumbuli and Dr. Euzobia Mugisa Baine and other officials for a group photo at the Rugby Grounds on 24th November 2025. Makerere University in partnership with Embassy of Sweden in Uganda and UNFPA in Uganda hosted the "Strides for Change" Activism walk and official unveiling of the 2025 16 Days of Activism campaign on Monday 24th November, 2025.

Makerere University in partnership with the Embassy of Sweden in Uganda and UNFPA in Uganda hosted the “Strides for Change” Activism walk and official unveiling of the 2025 edition of the 16 Days of Activism campaign on Monday 24th November, 2025.

Heads of Diplomatic Missions are joined by Dr. Winifred Kabumbuli and Dr. Euzobia Mugisa Baine (Right) as they march with the banner along Mary Stuart Road. Makerere University in partnership with Embassy of Sweden in Uganda and UNFPA in Uganda hosted the "Strides for Change" Activism walk and official unveiling of the 2025 16 Days of Activism campaign on Monday 24th November, 2025.
Heads of Diplomatic Missions are joined by Dr. Winifred Kabumbuli and Dr. Euzobia Mugisa Baine (Right) as they march with the banner along Mary Stuart Road. Courtesy Photo.

The event was graced by Heads of Diplomatic Missions from Sweden, Australia, Ireland and Germany alongside representatives from UNFPA and UN Women. The dignitaries were received on behalf of Makerere University by the Vice Chancellor, Prof. Barnabas Nawangwe represented by the Dean of Students, Dr. Winifred Kabumbuli together with the Chief Gender Mainstreaming Officer, Dr. Euzobia Mugisha Baine.

Dr. Winifred Kabumbuli represented the Vice Chancellor. Makerere University in partnership with Embassy of Sweden in Uganda and UNFPA in Uganda hosted the "Strides for Change" Activism walk and official unveiling of the 2025 16 Days of Activism campaign on Monday 24th November, 2025.
Dr. Winifred Kabumbuli represented the Vice Chancellor. Courtesy Photo.

Makerere University remains dedicated to creating a safe, inclusive environment and promoting gender equality. Each of us has a role in building a society free from violence,” read the Vice Chancellor’s message.

Present to ensure that the students’ voice was heard loud and clear were members of the 91st Students Guild led by their President H.E. Churchill James Ssentamu. The “Strides for Change” walk that commenced at the CCE roundabout was led by the Heads of Diplomatic Missions and members of Management was at Mary Stuart Hall handed over to the Student leaders who carried the banner all the way to the Impis Rugby Grounds for the rest of the activities.

H.E. Churchill James Ssentamu alongside other Student Leaders hold the "Strides for Change" banner at Mary Stuart Hall. Makerere University in partnership with Embassy of Sweden in Uganda and UNFPA in Uganda hosted the "Strides for Change" Activism walk and official unveiling of the 2025 16 Days of Activism campaign on Monday 24th November, 2025.
H.E. Churchill James Ssentamu alongside other Student Leaders hold the “Strides for Change” banner at Mary Stuart Hall. Courtesy Photo.

Of significant importance was the announcement of Makerere University‘s Dr. Jimmy Spire Ssentongo and Dr. Amon Ashaba Mwiine among sixteen (16) male changes chosen to champion the fight against gender-based violence.

Dr. Jimmy Spire Ssentongo alongside some of the Male Change Makers. Makerere University in partnership with Embassy of Sweden in Uganda and UNFPA in Uganda hosted the "Strides for Change" Activism walk and official unveiling of the 2025 16 Days of Activism campaign on Monday 24th November, 2025.
Dr. Jimmy Spire Ssentongo alongside some of the Male Change Makers. Courtesy Photo.

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Strengthening South-South Academic Partnerships: Makerere University and Binary University Chart a Strategic Path for Innovation, Entrepreneurship and Women’s Leadership

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A group photo from the left; Puan Sri Datin, Prof. Dr. Rohini Devi, Tan Sri Dato Professor Joseph Adaikalam, Prof. Barnabas Nawangwe, Prof. Sarah Ssali and Al‑Haj Habib Kagimu, Honorary Consul to Malaysia. Makerere University has started preliminary discussions with Binary University of Management and Entrepreneurship (Malaysia) to deepen its global partnerships through high-level engagements, aimed at fostering innovation-driven education, entrepreneurship, and women’s leadership, Main Building, 21st November 2025, Kampala Uganda, East Africa.

A New Chapter in Uganda–Malaysia Higher Education Collaboration

Makerere University has started preliminary discussions with Binary University of Management and Entrepreneurship (Malaysia) to deepen its global partnerships through high-level engagements, aimed at fostering innovation-driven education, entrepreneurship, and women’s leadership. Chaired by the Deputy Vice Chancellor for Academic Affairs, Prof. Sarah Ssali, the meeting explored a structured framework for collaboration that responds to Uganda’s urgent need for skills development, job creation, and industry-aligned learning.

This emerging partnership reflects a shared vision: to move beyond traditional academic models towards a practical, industry-integrated, and entrepreneurship-focused education system that equips graduates with real-world skills and global competitiveness.

Responding to Uganda’s Employment Challenge Through Entrepreneurship

“While chairing the meeting, Prof. Sarah Ssali noted that Makerere University and other Universities, together, currently graduate over 35,000 students annually, yet the private sector creates only about 700 new jobs per year. With an expanding population and intense job competition, where a single vacancy can attract over 4,000 applicants, the urgency for alternative employment pathways is clear.

Makerere’s Innovation Hub and Centre for Entrepreneurship have become critical pillars in addressing this challenge. Through platforms such as the Innovation Expo, now in its third edition and featuring over 600 student exhibitions, the university continues to nurture problem-solvers, innovators, and job creators. This ecosystem aligns strongly with Binary University’s entrepreneurial philosophy, making the Centre for Entrepreneurship a natural anchor point for collaboration.

Binary University’s Industry Specialist Professional (ISP) Model

Binary University brings a unique global model that directly integrates industry practitioners into the classroom. Its Industry Specialist Professional (ISP) programme, operational since 1999, ensures students graduate with skills tailored to specific industry needs. Industry experts with decades of practical experience teach across disciplines such as: Artificial Intelligence and Data Analytics, Oil and Gas, Renewable Energy, Engineering, Film and Media Production to mention but a few.

“ With over 10,500 practising entrepreneurs in its ecosystem in Malaysia, Binary offers students direct mentorship and exposure to active business environments, ensuring graduates are not only employable but also entrepreneurial.” Tan Sri Dato Professor Joseph Adaikalam, the Executive Chairman and Founder, Binary University of Management and Entrepreneurship, noted.

Tan Sri Dato Professor Joseph Adaikalam signs the Vice Chancellor’s Visitor’s book. Makerere University has started preliminary discussions with Binary University of Management and Entrepreneurship (Malaysia) to deepen its global partnerships through high-level engagements, aimed at fostering innovation-driven education, entrepreneurship, and women’s leadership, Main Building, 21st November 2025, Kampala Uganda, East Africa.
Tan Sri Dato Professor Joseph Adaikalam signs the Vice Chancellor’s Visitor’s book.

Key Areas of Proposed Collaboration

The discussions outlined a structured and scalable partnership model anchored on the following areas:

1. Dual and Joint Degree Programmes

  • 2+2 Joint Bachelor’s Degrees in specialised fields through an International Department structure.
  • 1+1 Joint Master’s Programmes including: MBA for Engineers, Renewable Energy MBA and Semiconductor MBA
  • Dual award systems to ensure international recognition and student mobility.

2. PhD and Staff Development Programmes

  • Winter/Summer PhD models in Renewable Energy and Waste Management
  • Nominated students to benefit from 50% tuition waivers
  • PhD pathways tailored for academic staff development

3. Executive Development Programmes (EDPs)

High-impact, short-term programmes targeting senior leaders, featuring joint certification with a focus on AI for CEOs, Global Issues & Entrepreneurship. These EDPs are designed to empower leaders with strategic insight into global trends, innovation, and entrepreneurship.

Placing Women’s Leadership at the Centre

A key pillar of the proposed collaboration is engagement with Malaysia’s Centre for Women’s Leadership (CWL), which focuses on empowering women through entrepreneurship and gender compliance mechanisms.

Puan Sri Datin, Prof. Dr. Rohini Devi, the co-founder and Vice Chairman, Binary University, highlighted the unique opportunities this partnership presents for a Joint women’s leadership training initiative, feminist academic exchanges, gender-responsive entrepreneurship models and an initiative to strengthen Makerere’s Institute of Gender Studies as a regional hub.

This aligns with Malaysia’s progressive gender compliance policies for public funding and women’s leadership development, a model that holds strong relevance for African institutions.

Puan Sri Datin, Prof. Dr. Rohini Devi receives a souvenir from the Vice Chancellor, Prof. Barnabas Nawangwe. Makerere University has started preliminary discussions with Binary University of Management and Entrepreneurship (Malaysia) to deepen its global partnerships through high-level engagements, aimed at fostering innovation-driven education, entrepreneurship, and women’s leadership, Main Building, 21st November 2025, Kampala Uganda, East Africa.
Puan Sri Datin, Prof. Dr. Rohini Devi receives a souvenir from the Vice Chancellor, Prof. Barnabas Nawangwe.

Learning from Regional and Global Best Practices

The meeting underscored valuable lessons from global contexts, including Nigeria’s model, where every graduate leaves with a practical vocational skill, Zambia’s Winter-Summer academic model with tuition waivers, Malaysia’s government investment in higher education and entrepreneurship

These case studies reinforce the need for practical skills as survival tools while graduates transition into formal employment or entrepreneurship.

A Win-Win Partnership for the Future

This collaboration is envisioned as a mutually beneficial model that complements Makerere’s academic strengths while leveraging Binary’s industry-driven approach. It will enhance student mobility, staff exchange, joint research, innovation transfer, and entrepreneurship development, all while maintaining strong quality assurance mechanisms.

As Makerere University continues to reimagine higher education in a rapidly changing world, this partnership signals a transformative shift towards globally competitive, innovation-led, and socially responsive learning systems.

With optimism and strategic intent, both institutions commit to open dialogue, structured implementation, and long-term impact. The Makerere-Binary partnership stands as a powerful example of how South-South collaboration can redefine education, accelerate entrepreneurship, and empower future leaders, especially women, for Africa’s development trajectory.

Caroline Kainomugisha is the Communications Officer, Advancement Office, Makerere University.

Caroline Kainomugisha
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