Plants have traditionally been used as a source of lead compounds in the development of drugs. Plants have also been the source of several drugs, which are currently the mainstay for the treatment of major diseases such as malaria and cancer. This has led to continued research for new drugs, leading to new bioprospecting initiatives for novel lead compounds. However, there are challenges that have been encountered in drug discovery from plants, which have led to many pharmaceutical companies shunning away from this venture. In this chapter, we (Godwin Anywar and Jane Namukobe) discuss the factors affecting the choice for plant-based products in drug discovery. The main factors considered include abundance of plant or sources material, efficacy of plant material/compound, ease of structural modification, molecular size, toxicity, and stability of the compounds. Highlights on how and why each of these factors is considered important have been addressed.
Under the theme, “Leveraging AI for Sustainable Transformation: Leading in Uganda’s Transformation in the Age of Disruptive AI,” the 16th Annual CEO Forum 2025 brought together government leaders, captains of industry, academia, and development partners to discuss how Artificial Intelligence (AI) can drive Uganda’s transformation agenda.
Representing the Vice Chancellor, Mr Yusuf Kiranda, University Secretary at Makerere University, reaffirmed the University’s pivotal role as a hub for AI research, innovation, and training anchored in strong partnerships across government, academia, and industry.
“Makerere University is responsible for research, innovation and training to ensure transferable knowledge that can be utilised by both the private and public sector,” Mr. Kiranda noted.
He emphasised that Uganda’s sustainable AI transformation will depend on effective policy, governance, and collaboration across sectors.
According to Mr. Kiranda, three key issues must be addressed for AI to realise its potential:
Balancing control and facilitation: Policymakers must not only regulate AI but also actively enable its use to drive innovation and competitiveness.
Sovereignty of AI: Uganda must safeguard its data and resources, especially in sectors like agriculture, where external mapping of local assets threatens national control and export competitiveness.
Regional harmonisation: To ensure fair competition, AI policies must be aligned across East Africa so Ugandan, Kenyan, and Tanzanian businesses operate under a level playing field.
“In the utilisation of AI, if a policy is making Uganda less competitive, we must revise it now to allow private sector players to thrive in this disruptive age,” he added.
Mr. Kiranda further reiterated Makerere’s commitment to producing quality, AI-ready graduates and enhancing teaching and learning methods to integrate technology. He also acknowledged the Government’s continued investment in research at Makerere, which has seen a growing number of researchers focus on AI and technological innovations.
Mr. Yusuf Kiranda participating in a panel discussion at the #CEOForumUg2025.
“I can attest to Makerere’s existing partnerships with government entities and development partners. These collaborations are making the market ready to deliver solutions through effective academia–industry partnerships,” he said.
Building Africa’s Digital Destiny
The forum opened with a powerful keynote from Dr. Robin Kibuka, Board Director at the CEO Summit Uganda, who spoke on “Building Africa’s Digital Destiny: Kampala Rising, Africa Inventing.”
Dr. Kibuka urged Africans to take ownership of their digital future, stressing that the continent must define how AI transforms its societies.
“Artificial Intelligence can empower Africa or divide it. The choice is ours,” he said.
He highlighted success stories from across Africa, including AI-powered drones delivering medical supplies and smart credit systems supporting small businesses — proof that the continent is already innovating its own digital solutions.
Dr. Robin Kibuka addressing the CEO Summit Uganda 2026.
Leveraging AI for Sustainable Transformation
In her keynote address on “Leveraging Artificial Intelligence for Sustainable Transformation,” Dr. Preeti Aghalayam, Director of the Indian Institute of Technology Madras – Zanzibar Campus, described AI as “the defining disruptor of the 21st century.”
She emphasised that both Africa and India share a unique opportunity to collaborate in education, innovation, and human capital development to shape a more inclusive digital future.
“Artificial Intelligence must help us do better and be better,” she said, highlighting the need for responsible innovation that uplifts communities and promotes sustainability.
Dr. Preeti Aghalayam delivering her keynote address.
Digital Transformation in the Health Sector
Mr. Rashid Khalani, Chief Executive Officer of Aga Khan University Hospital, Uganda, presented on “Digital Transformation in the Health Sector,” sharing practical examples of how AI is redefining healthcare delivery.
From AI-powered radiology that detects anomalies faster, to predictive models for early sepsis detection and digital tools supporting mental health care, Mr. Khalani demonstrated how AI is improving patient outcomes and empowering medical professionals.
“AI is not replacing people. It is empowering them to deliver better care, faster,” he emphasised.
He noted that partnerships between hospitals, universities, and technology institutions are crucial in developing localised AI solutions that respond to real health needs.
Mr. Rashid Khalani discussing AI in the health sector.
Makerere at the Heart of Uganda’s AI Transformation
The discussions throughout the 16th Annual CEO Forum 2025 reaffirmed the critical importance of collaboration among academia, industry, and government in shaping Uganda’s AI-driven future.
Makerere University continues to play a leading role in this space, providing the research, innovation, and talent that power the country’s transition into a digital economy.
Through strategic partnerships, forward-looking policy engagement, and continuous innovation in research and training, Makerere stands at the forefront of preparing Uganda and the region for a smart, inclusive, and sustainable future powered by AI.
Caroline Kainomugisha is the Communications Officer, Advancement Office, Makerere University.
The applications for scholarships to the second edition of the Erasmus Mundus Joint Master on Coordinated Humanitarian Response, Health and Displacement are open. The deadline is 09.01.2026 (9 January 2026), at 17.00, CET time (19.00 EAT).
Requirements
Mandatory documentation to upload is:
Valid Passport
Photograph
Diplomas (from previous degrees completed)
Transcript of records (diploma supplement) with all courses and grades (from previous completed degrees)
English proficiency test results certificate (from one of the required tests). Code for certificate validation.
Curriculum vitae
Statement of purpose (mandatory to upload a pdf document)
2 signed and dated Recommendation Letters
All of the identified documentation is mandatory. Applications missing any of the above mentioned documents will not be considered as eligible.
Only candidates with a Bachelor degree (180 ECTS) can be admitted.
The 5th African Research Universities Alliance (ARUA) Biennial International Conference at Makerere University closed on Friday 31st October 2025 after three rich days of debate, learning, and inspiration. Delegates were kept engaged by keynote addresses, roundtable discussions, and various parallel sessions as well as poster presentations that brought forth ideas from ongoing research and innovations. The atmosphere at the closing session was warm but purposeful, as speakers reflected on achievements and affirmed a shared duty to shape Africa’s research future in Artificial Intelligence (AI) with conviction and unity.
The Secretary-General ARUA, Prof. John Owusu Gyapong, thanked delegates for their dedication and vibrant engagement throughout the three days, noting that the rich exchanges and collaborative spirit demonstrated ARUA’s growing strength and shared purpose. He expressed deep appreciation to keynote speakers, panelists, and partners for elevating the dialogue on Africa’s research and innovation future, and extended special recognition to the organising committees and Secretariat for their tireless work behind the scenes. He also encouraged members to continue building on the momentum and translating ideas into action across the continent.
Prof. John Owusu Gyapong.
Prof. Barnabas Nawangwe, Vice Chancellor of Makerere University the host, expressed deep appreciation to the delegates for their active participation and commitment throughout the three days, noting that their engagement reflected the strength and promise of Africa’s research community. He commended the Secretariat and the organising committee for delivering a seamless and impactful event, especially during a period of leadership transition, and congratulated them for upholding the high standards of ARUA. Reflecting on the future of artificial intelligence on the continent, he reaffirmed that Africa cannot afford to trail behind in the next technological era, emphasizing that the conversations and innovations shared at the conference are clear proof that the continent has the talent, vision and will to lead.
Prof. Barnabas Nawangwe.
Prof. Sizwe Mabizela Chairperson ARUA Board and the Vice Chancellor, Rhodes University expressed deep gratitude to Makerere University, Uganda, and all contributors, from planners to ushers and cultural performers. He highlighted the conference’s central insight: AI must empower and advance human creativity rather than replace it. He urged Africa to take full charge of its destiny through research, innovation, and unity, reminding participants that history will judge this generation by the solutions it builds. He officially closed the conference with wishes for safe travel and a call for peace.
Prof. Sizwe Mabizela (Standing) interacts with attendees during one of the parallel sessions.
The final roundtable discussion brought together senior university leaders to chart how African institutions can translate bold AI ideas into grounded action. Moderating the session, Prof. Nana Aba Appiah Amfo the Vice Chancellor, University of Ghana, framed the conversation around three guiding themes: responsible integration of AI in research and teaching, building sustainable funding and governance systems, and positioning ARUA universities at the center of Africa’s AI future.
Dr. Nomakwezi Mzilikazi, Deputy Vice Chancellor for Research, Innovation and Strategic Partnerships at Rhodes University emphasized that universities must begin by defining the real problems AI should solve for African societies, and embed those questions into institutional missions, engaged research, and capacity building.
Prof. Sarah Ssali cautioned that technology is never neutral and reminded participants that AI must reflect human dignity, agency, and African knowledge traditions, not simply mirror Western systems or deepen global and gender divides. She called for intentional policies, cultural awareness, and protections for indigenous and marginalized communities whose knowledge and identities are often overlooked.
The Policy Roundtable and Wrap-Up with Left to Right: Prof. Nana Aba Appiah Amfo, Dr Nomakwezi Mzilikazi, Prof. Sarah Ssali, Prof. David Asamoah, and Prof. Oluyemisi Bamgbose, SAN.
Drawing from industry-facing experience, Prof. David Asamoah, Vice-Chancellor of Kwame Nkrumah University of Science and Technology (KNUST), Ghana stressed that universities must move beyond isolated pilots and adopt ecosystem thinking, interoperability, national frameworks, phased implementation, and strong links with industry to scale AI meaningfully.
Speaking virtually, Prof. Francis Peterson, Vice Chancellor of the University of Pretoria, encouraged institutions to develop and share higher-education AI frameworks, case studies, and collaborative models, and to build stronger partnerships outside academia to turn research into practice.
Prof. Oluyemisi Bamgbose, SAN, Deputy Vice Chancellor for Research, Innovation, and Strategic Partnerships, University of Ibadan, Nigeria emphasized the legal and ethical backbone needed to support all these ambitions, outlining governance structures, transparency, intellectual property safeguards, and accountability systems that protect academic integrity without choking innovation.
Samantha Carter presents the sixth keynote address.
The last day of the conference also featured two forward-looking keynote addresses that grounded the conversation in real-world application and evidence. Darlington Akogo, Founder and CEO of minoHealth AI Labs, demonstrated how Africa can lead in health innovation by designing and deploying AI tools developed on the continent, for the continent. Samantha Carter, Senior AI Policy Manager at J-Pal, followed with a data-driven case for using AI to tackle inequality and poverty.
In closing, Prof. Gyapong announced that the next ARUA Biennial Conference will be hosted by Rhodes University in the Eastern Cape, South Africa, from 27th to 29th October 2027. Delegates were encouraged to mark their calendars and begin preparing for meaningful engagements on how AI can be harnessed to better shape Africa’s future.