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Study to Address the Social drivers of Mental Illness Launched in Uganda by Kennesaw State University & Makerere University

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A new 5-year study has been announced to determine the link between social drivers and mental health among young women who live in the slums of Kampala in Uganda.  Kennesaw State University (KSU) received the five-year $3.3 million award from the National Institutes of Health (NIH) and has partnered with Makerere University to conduct this interdisciplinary project.  

Mental illnesses are understudied, and scarce services lack evaluations, particularly in low-resource settings such as slums. In response to the vulnerable state of adolescent girls and young women in the urban slums, the team of researchers are implementing this five-year project named “TOPOWA” (The Onward Project On Well-being and Adversity), which means to “keep pushing forward and never giving up”, in the Luganda language.

Makerere University through the School of Public Health is teaming up with two U.S universities, Kennesaw State University (KSU) and Georgia State University (GSU) in the U.S. to implement the research component of the study. The Uganda Youth Development Link (UYDEL), a community-based organization in Kampala will lead the intervention components.

Some of the beneficiaries of the TOPOWA Project attend a tailoring course.
Some of the beneficiaries of the TOPOWA Project attend a tailoring course.

First of its kind, “the TOPOWA project will examine if a community-based intervention program comprised of vocational training, entrepreneurship and economic empowerment, team building through sports, and psychosocial support (“Socioeconomic Strengthening Targeted Training: “SeSTT”). leads to better mental health outcomes among disadvantaged women living in slums” said Dr. Monica Swahn, the Principal Investigator of the study.

The TOPOWA research project will focus on young women ages 18-24 years, the age period when most mental health symptoms are manifested and expressed. If the study shows that the intervention makes a difference in mental health outcomes (i.e., anxiety, depression, suicidality and substance use symptoms and disorders) for young women, it can address the tremendous unmet mental health needs in Uganda. The study will also increase the understanding of the community and neighborhood characteristics of the urban slums where the young women reside.

It was launched on Tuesday March 8, 2022, on International Women’s Day, a global holiday celebrating the social, economic, cultural, and political achievements of women. Speaking at the launch, Dr. Swahn, the Principal Investigator, and also Professor and Dean of the Wellstar College of Health and Human Services at KSU said “TOPOWA was in support of global action to advance gender equality and the empowerment of women and girls”

Dr. Swahn, the Principal Investigator, and also Professor and Dean of the Wellstar College of Health and Human Services at KSU
Dr. Swahn, the Principal Investigator, and also Professor and Dean of the Wellstar College of Health and Human Services at KSU

She also noted that this was a ground-breaking study, with investigators representing diverse expertise from three universities.

“Our TOPOWA project is ground-breaking because we look at the social drivers of mental illness and how to mitigate them. We conceived this project before the pandemic, but now with the pandemic, we know more than ever how mental health has been understudied and the growing scope of unmet need in the community,” she said.  Dr. Swahn also added that, “We don’t have enough interventions for mental health in particularly among vulnerable populations in low-resource settings. So, what we have learnt post-COVID is that we need to find scalable interventions to better support mental health for women who live in poverty, particularly women who live in slums.”

Using a multicomponent 27-month, parallel prospective cohort design of young women, the study team will recruit 300 participants from three selected UYDEL study sites in Banda, Bwaise and Makindye to determine the pathways and mechanisms of mental health outcomes.  The study will involve focus groups, a Photovoice project, community mapping, surveys, use of sleep wearables, saliva and stress reactivity to detect and determine stress levels of the young women.

The investigators will measure stress though threat reactivity in fear conditioning tests, ratio of salivary cortisol, dehydroepiandrosterone (DHEA) and α-amylase, and sleep quality by deploying Fitbit wearable sensors for each study participant as well measuring environmental stressors through geotrackers.

“We will ask these young women to wear these Fitbits. These will pick up on the measure of sleep. We know that when people are stressed, they have poor mental health, but also, they have poor sleep,” said Prof. Swahn.  She adds that these Fitbit devices are worn just like a wrist watch. “They will give us a lot of insight to what happens at night when people are sleeping. The women may or may not be sleeping as well as they should. So again, it’s another marker of stress, their well-being and physical health. It really adds another important innovative component of the study. We looked for other studies across the sub-Saharan Africa and have not found any studies that use this technology in this type of setting so these gadgets will give us a lot of insight.”

Some of the young women beneficiaries of the project entertain visitors at the Bwaise UYDEL site
Some of the young women beneficiaries of the project entertain visitors at the Bwaise UYDEL site

Dr. Catherine Abbo, an Associate Professor of Psychiatry at Makerere University College of Health Sciences, and Co-Investigator of the TOPOWA study, says depression and other mental health issues are on the rise in Uganda, though they continue to go unrecognized.

“These women actually don’t even reach the clinic but people just suffer while they are in the communities. There are different anxiety disorders. So, the current estimates from the previous research shows about 1 in every 4 people have mental health issues,” Dr. Abbo says.

Asked about what could be the drivers of mental health in young adults, Dr. Abbo contends some of the drivers are psychosocial arising from the environment we live in while others maybe genetically predisposed.

Dr. Catherine Abbo, an Associate Professor of Psychiatry at Makerere University College of Health Sciences, and Co-Investigator of the TOPOWA study.
Dr. Catherine Abbo, an Associate Professor of Psychiatry at Makerere University College of Health Sciences, and Co-Investigator of the TOPOWA study.

“If you are going to live in an environment that is poverty stricken, you are going to live in an environment where you are not going to access education, you are not going to have support that you need to be mentally healthy, you become vulnerable to getting mental illness and that is the environmental aspect. And then we have individuals, who, because of their genetic makeup, may develop cause mental illness,” she said.

According to Dr. Abbo, the wearables are new technologies and that this is the first of its kind to be used in research in Uganda. “You know sometimes people go jogging and have phones that take the number of their steps, heart rate, so in the general population we have gadgets that can measure some aspects of body reactions but particularly in this case, it’s going to measure sleep patterns, that signify stress levels.”

Mr. Rogers Kasirye, UYDEL’s Executive Director, argues that many a time, intervention projects have been implemented among youth but they fail because of the inability to tackle underlying issues affecting the young people. He says this study to investigate the mental health status of the young women will go a long way in impacting the way such initiatives can be implemented to achieve greater success.

Executive Director of UYDEL, Rogers Kasirye.
Executive Director of UYDEL, Rogers Kasirye.

According to Mr. Kasirye, for over 25 years, UYDEL has worked with young people in the in the slums of Kampala and impacted many young people through their skilling and rehabilitation programs. He pointed out that  that a majority of the young people in slums face a lot of challenges including poverty, lack of shelter while others have long lost contact with their families.

“But we don’t go beyond to investigate and support their psychosocial needs. From experience, some people who come to our facilities have alcohol and other problems. Many times, they are even failing to sleep. Some even come to the Centre and tell you that they have not had a meal. You know what it means to sleep on an empty stomach. Others say they lost contact with their families while others say they have been sexually abused and others raped. In other words, they have a mountain of psychosocial needs that must be addressed. With this project, we hope to track girls for several years to match the research findings with empowerment interventions,” said Mr. Kasirye.

TOPOWA Study PI Prof. Monica Swahn interracts with Makerere University School of Public Health team. In the photo, Dr. JB Isunju, Mr. Charles Ssemugabo and Ezekiel Musasizi.
TOPOWA Study PI Prof. Monica Swahn interracts with Makerere University School of Public Health team. In the photo, Dr. JB Isunju, Mr. Charles Ssemugabo and Ezekiel Musasizi.

Ms. Anna Kavuma, the Deputy Executive Director, UYDEL says the COVID-19 pandemic has had a toll on mental health issues among young women by increasing their vulnerability.

She notes that whereas the boys have equally been affected by the pandemic and could have pushed them to high stress levels, girls have a high level of vulnerability with responsibilities such as bringing up the children, dealing with pregnancies, accessing medical supplies as well as shelter.

Ms. Anna Kavuma, the Deputy Executive Director, UYDEL.
Ms. Anna Kavuma, the Deputy Executive Director, UYDEL.

“It’s quite difficult for the girls. It’s an understatement for me to say that they are not highly affected by mental issues in Uganda, that is why this project is coming in to understand that. For instance, if we gave young girls vocational skills and training in beauty and cosmetics, or any other vocational skilling, will it help reduce on these stresses that they have? Will it help address the underlying factors that they are facing? Will it help to improve  the way they sleep? Will it help improve  the stress levels? These are areas we are trying to study and we are hopeful that the results of the study will inform not only programming and practice but also inform policy environment as well,” said Nabulya.

The project’s intervention arm will look at skilling the adolescent girls and young women with the cost-effective beauty training, which the researchers say is also very easy to implement. Dr. Swahn, the PI noted, “We are hoping that if it’s shown to be effective, that is something that can be implemented in other communities and we know that many are offering vocational training but they have not been evaluated the way we are doing it with a very vigorous scientific protocol.

The TOPOWA Research team.
The TOPOWA Research team.

Dr. Rhoda Wanyenze, Professor and Dean, Makerere University School of Public Health thanked Prof. Swahn and UYDEL for partnering with MakSPH to implement this important project citing that the School was ready to work with the team.

“Mental health for young people is such an important area and very timely coming after the challenges and stress from the Coronavirus pandemic! We are excited to partner with you on this project,” said Prof. Wanyenze.

The TOPOWA Research Team is composed of nine investigators spanning two continents and three universities.  The Project’s Principal Investigator (PI) is Dean and Professor Monica Swahn of Kennesaw State University. The Co-Investigators of the project include Dr. Cathy Abbo, Dr. Godfrey Bbosa, Dr. John Bosco Isunju, Charles Ssemugabo and Dr. Eddy Walakira from Makerere University, Dr. Ebony Glover from KSU and Dr. Rachel Culbreth and Dr. Karen Nielsen from GSU.

TOPOWA Pictorial.
TOPOWA Pictorial.

The Executive Director of UYDEL, Rogers Kasirye, leads the implementing partner whose mission is “to enhance socioeconomic transformation of disadvantaged young people through advocacy and skills development for self-reliance”.  

The TOPOWA Project Advisory Board is composed of members from the Kampala City Government, the Ministry of Health, the Ministry of Gender Labour and Social Development as well as the Dean for the Makerere University School of Public Health.

Davidson Ndyabahika is the Communications Officer, MakSPH/TOPOWA Project

Article originally posted on MakSPH website

Davidson Ndyabahika

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JASH2025 wraps with the 23rd Matthew Lukwiya Memorial Lecture and Kampala Declaration Statement

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Panelists moderated by ED IDI-Dr. Andrew Kambugu (Left) reflect on Dr. Lukwiya's legacy during the 23rd Matthew Lukwiya Memorial Lecture on 7th November 2025. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.

The 19th Joint Annual Scientific Health Conference (JASH) and Inaugural National Annual Communicable and Non-Communicable Conference (NACNDC) held at Speke Resort Munyonyo ended on Friday 7th November, 2025 with the 23rd Matthew Lukwiya Memorial Lecture and a Kampala Declaration Statement.

The joint conference that began on 3rd November, 2025 themed, ‘Unified Action Against Communicable and Non-Communicable Diseases’ was organised by Makerere University College of Health Sciences (MakCHS), Makerere University School of Public Health (MakSPH) and Ministry of Health (MoH). The meeting brought together representatives from Central Government, Ministry of Health, academia, civil society, local governments, private sector, development partners, professional associations, local governments and communities.

Kampala Declaration Statement

Dr. David Musoke, Assoc. Professor at MakSPH who was Co-Chair of the Organising Committee delivered the Kampala Declaration which defined the priorities/commitments of the delegates from the dialogue at the conference.

The declaration highlighted the background of setting the priorities as thus: 1. Uganda’s dual disease burden from communicable diseases (CDs) alongside the growing rise of non-communicable diseases (NCDs). 2. The biological, social and clinical intersections between CDs and NCDs, which compete for limited resources. 3. Threats posed by antimicrobial resistance (AMR), climate-sensitive diseases, zoonotic spillovers, and emergency outbreaks such as Ebola, COVID-19, and Marburg. 4. Uganda’s commitment to Universal Health Coverage (UHC), the Africa CDC’s New Public Health Order, the Sustainable Development Goals (SDGs), the International Health Regulations (IHR), the International Covenant on Economic, Social and Cultural Rights, and the Global Health Security Agenda (GHSA). 5. The integration of health services at facility level continues to face challenges due to high patient-to-health worker ratios and inadequate infrastructure, which impede the delivery of comprehensive, timely, and quality healthcare services;

Emphasizing the need to involve all stakeholders—including from education, agriculture, environment, engineering, urban planning, gender, as well as community and religious leaders, and others—in the fight against communicable and non-communicable diseases; 6. The persistent challenges in access to healthcare across the country due to delays in diagnosis and treatment-seeking, and emphasizing the urgent need to strengthen early detection, ensure timely access to quality healthcare, and enhance community awareness about prompt medical attention; 7. Protection and promotion of human rights are fundamental to ensuring health, dignity, and well-being for all citizens, as these rights form the  foundation of equitable access to quality healthcare services; 8. The global threat of antimicrobial resistance (AMR), now causing an estimated 700,000 deaths annually, and recognizing its strong link to self-medication, poor diagnostic capacity, and weak public health interventions; 9. Health policies and investments have focused more on curative than preventive care, underscoring the need to reinstate a strong prevention-oriented approach; 10. Many Ugandans remain inadequately informed about health issues affecting them and their role in promoting health within their communities; 11. Rapid industrialization, urbanization, and lifestyle changes are significantly contributing to the rising burden of NCDs;

The Kampala Declaration was presented as a shared call to action, a platform for sustained collaboration, and a blueprint for strengthening integrated and equitable health systems. The declaration is premised on the following priorities:

  • Multisectoral Collaboration and One Health Approach: Affirmation of the requirement for involvement of the whole-of-society and whole-of-government approach to accelerate disease prevention, health promotion, and self-care through evidence-based awareness.
  • Integrated, People-Centered Disease Prevention and Care: The urgent need to focus on people, not diseases, using a life-course approach and strengthening integrated service delivery across CDs and NCDs at all levels.
  • Strengthened Data, Research, and Policy Translation: Recognition of the importance of timely, interoperable, and disaggregated data to inform policy, financing, and implementation decisions. In addition, commit to collaboration between academic institutions, policymakers, CSOs, and community influencers to bridge the gap between research and practice.
  • Financing: Commit to advocate for increased domestic financing to progressively reduce dependence on external aid, ensuring predictable and sustainable resources for integrated disease prevention and care. Promote efficiency and accountability in health spending by strengthening budget tracking, performance-based financing, and public financial management systems. Support innovative financing mechanisms, including public-private partnerships, social health insurance, and community-based financing schemes to expand coverage and affordability.

Specific calls were directed to the various stakeholders respective to their mandates and roles.

Government of Uganda and the Ministry of Health: To accelerate implementation of integrated strategic plans for CDs, NCDs, and epidemic preparedness under a unified health systems approach; Institutionalize NACNDC–JASH as the official Annual Integrated National Health platform for disease dialogue and innovation, co-led by the Ministry of Health and academia; Mobilize domestic and international financing to strengthen primary healthcare, laboratory networks, and community systems; Enforce laws and policies aimed at preventing and controlling substance abuse nationwide.

Academia: Generate policy-relevant evidence and drive innovation in diagnostics, surveillance, and culturally appropriate care; Establish multidisciplinary working groups to connect research, clinical practice, and policy; Train health professionals in integrated, competency-based, and future-ready approaches; Create innovation hubs and partnerships linking academia, communities, and industry to co-develop scalable, people-centred solutions; Leverage technology and innovation to effectively address CDs and NCDs; and Prioritize locally led research focused on Uganda’s health realities, including NCDs, CDs, mental health, and climate-linked risks.

Development Partners and Donors: Align technical and financial support with Uganda’s integrated disease control priorities; Support the development of a national research agenda driven by local health needs; Strengthen health system resilience, digital transformation, and community-led interventions; and promote regional knowledge sharing, South-South collaboration, and local manufacturing of diagnostics and medicines.

 Private Sector and Civil Society: Engage in public-private partnerships to expand access to diagnostics, care, and innovation; Champion community-responsive models for disease prevention; rehabilitation, and continuity of care; Strengthen advocacy, accountability, and public education through multimedia and grassroots platforms; Raise public awareness on mental health, sickle cell disease, asthma, and diabetes, integrating these services into primary care and reducing stigma and discrimination.

In view of the background, priorities and expected action from the stakeholders as highlighted above, the declaration also endorsed the development and dissemination of: a National Integrated Disease Control Strategy, informed by best practices and policy dialogues from this conference; a Multisectoral Action Framework guiding collaboration among health, education, agriculture, environment, and finance sectors; A Monitoring Mechanism to track implementation and institutionalize annual

reporting on disease integration; and the continuation of joint annual NACNDC and JASH conferences to sustain momentum.

Setting the Pace

Through the conference, keynote speakers delivered addresses which set pace for the dialogue by participants at the conference.

Dr. Queen Dube, Lead – Newborn Programme Implementation, Policies and Standards at the World Health Organisation (WHO), Geneva and Co-Chair of Every Woman, Every Newborn (EWENE) Country Implementation Group highlighted the reasons for rising disease burden of NCDs across sub-Saharan Africa including industrialization and urbanization; shifting dietary patterns; improved means of transport and communication which converts to less movement.

Dr. Dube noted that, the poorer one is, the higher the risk of one dying due to an illness either through communicable or non-communicable diseases. She stressed the importance for a unified action against diseases as opposed to fragmentations or silos by different working groups of various diseases. Duplication of efforts spreads thin the available resources, yet more efficiency and effectiveness could be enjoyed, she added.

Her call for action was, ‘health is interconnected, our response must be to; collaboration saves lives; and together, we can build a healthier, more resilent world’.

Prof. Francis Omaswa delivers the keynote address. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Francis Omaswa delivers the keynote address.

Delivering his keynote speech on the final day of the conference, Prof. Francis Omaswa, Founder and Director – African Centre for Global Health and Social Transformation (ACHEST) reminded the delegates that, ‘it is up-to us to achieve our goals provided we commit to do what is expected of us in the best possible way’.

He questioned why Africa continues to lag behind in the global health indices considering the professionals present on the continent. ‘Inclusiveness, equity and working together is the way forward’, he advised.

Prof. Omaswa reminded the delegates that Uganda in particular achieved in areas like HIV/AIDS control, therefore the means we used then must be employed in fighting communicable and non-communicable diseases. He heighted that, some of the means included leadership at all levels, working together, for monitoring and reporting, engagement of youth through the means they respond to among others.

Prof. Francis Omaswa (2nd Right) with panelists that discussed his keynote address. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Francis Omaswa (2nd Right) with panelists that discussed his keynote address.

‘Let no one go to sleep, each one of us is a leader at our levels of responsibility and we must make sure that there is coordination and supportive supervision within the health system’, Prof. Omaswa reiterated.

In his keynote speech, Dr. David Serwadda, a Professor in the Department of Disease Control and Environmental Health at MakSPH reminded researchers and academia the importance of their work to disease prevention and control. He stressed that the link between research and implementation is critical for a unified action, and there bridging the gap must be intentional.

Prof. David Serwadda delivers his keynote address on "Health Systems Resilience Amidst Global Funding Cuts: What African Countries Must Do". Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 6th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. David Serwadda delivers his keynote address on “Health Systems Resilience Amidst Global Funding Cuts: What African Countries Must Do”.

23rd Dr. Matthew Lukwiya Memorial Lecture

Dr. Matthew Lukwiya is remembered for his leadership and selflessness as a Ugandan physician at the forefront during the Ebola virus disease outbreak in Uganda in 2000 until de succumbed to the disease. He was the supervisor at St. Mary’s Hospital Lacor, outside Gulu City, Uganda; Gulu district was an epicentre of the disease at the time.

As has been the case at the previous JASH conferences, the 23rd edition of the Matthew Lukwiya Memorial Lecture was held on the final day of the conference, themed, “Identified Critical Gaps in the Response to Outbreaks”.

The session convened leading scientists, policymakers, community and health professionals to reflect on lessons learnt from past epidemics and chart strategies for stronger preparedness, response and resilience across the health system.

The Way forward

At the end of the meeting, delegates were advised that information from the meeting will be shared through a link on the MakSPH website and abstracts will be published as well.

Prof. Rhoda Wanyenze, Dean-MakSPH who also represented Prof. Bruce Kirenga, Principal-MakCHS thanked all participants for attending the dual conference and willingness to share information in support of integrating to improve Uganda’ Health System. She also thanked the organising committee and partners for the support leading to a successful conference.

‘What is it that touched you at this conference, what are the takeaways and I implore you to reflect on the discussions and create a change. This is not business as usual and let us make change.’, the Dean said.

Prof. Wanyenze handed the baton to the School of Medicine who will work with the MoH in organising the conference in 2026.

Closing by the Permanent Secretary

PS-MoH, Dr. Diana Atwine. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
PS-MoH, Dr. Diana Atwine.

The conference was officially closed by Dr. Diana Atwine, Permanent Secretary-MoH. She highlighted five points for all of us to remember as takeaway from the dialogue.

  • All of us should innovate solutions for the challenges before us including innovative leadership. Uganda’s population growth remains high and the resources are not growing at same rate therefore challenges will continue to arise therefore innovation is necessary.
  • Inculcate a culture and mindset change and remember health change begins with each of us.
  • Integrate not verticalization because it is the right thing to do, leads to efficiency and gives results.
  • As government continues to explore means of resource mobilisation, smart investments in high impact activities and priorities are critical.
  • Call upon all of us, to implement the resolutions reached.

She thanked all stakeholders for the contributions made towards success of the conference.

Zaam Ssali

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2nd AI in Health Africa Conference, Not about Tech but the Vulnerable

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Hon. Dr. Monica Musenero (3rd Right) flanked by Left to Right: Mr. Ambrose Ruyooka, Dr. Rose Nakasi, Dr. Stella Kivila, Prof. Buyinza Mukadasi and Dr. Andrew Kambugu at the Conference Opening Ceremony on 6th November 2025. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.

The two-day 2nd Artificial Intelligence (AI) in Health Africa Conference that kicked off today in the Main Hall, Makerere University has been described as not being about technology but about people – the vulnerable communities bearing the burden of infectious diseases and other health challenges – and the promise AI holds as a panacea. Officially opened by Hon. Dr. Monica Musenero, Minister of Science, Technology and Innovation the conference will be held under the theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”.

Africa Must Enter the ‘Evil Forest’

In her now characteristic style of speaking from the heart, Hon. Dr. Musenero observed that Africa has from the first industrial revolution to the current fourth and impending fifth industrial revolutions experienced emotions ranging from non-recognition, rejection and skepticism to the current consumption with awe. This current emotion, though receptive unlike previous ones, continues to position Africa at a disadvantage economically, she noted.

Hon. Dr. Monica Musenero delivers her keynote address. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero delivers her keynote address.

“We are positioning ourselves to disadvantage in skill; we have positioned ourselves at the consumption end and we’ve stood in awe of this technology,” she observed, using the example of the amount of admiration a user who whips out the latest iPhone 17 attracts from those around them. “We respect you for your iPhone 17, but I would be happier if you were able to design and manufacture iPhone 5” intimated Hon. Dr. Musenero.

The Minister urged fellow scientists to wake up to the realization that the future of Africa lies in their hands. “We can no longer be passive participants, we can no longer reside on the shallow end of science; we must be willing, as I said when I was here last week, to enter the ‘evil forest’”.

Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony.

The ‘evil forest’ is Hon. Dr. Musenero’s analogy of Africa’s perception of current technology ecosystem drawing parallels with scenes often dramatized by Nigerian Movies. She notes that though depicted in these movies as scary and potentially dangerous, the ‘evil forest’ is loaded with hidden treasures, necessitating resilience and wisdom for one to navigate the pitfalls until they discover the treasure trove. Upon discovery, the value of this treasure has the potential to turn around the fortunes of the family, community or entire kingdom. Entering the ‘evil forest’ therefore, is her way of encouraging scientists to go beyond adapting imported technology for local use to understanding how it works enough to develop homegrown solutions.

Building AI Capacity through Synergy

Representing the Vice Chancellor, Prof. Barnabas Nawangwe, the Academic Registrar, Prof. Buyinza Mukadasi concurred with Hon. Dr. Musenero that Uganda needs to accelerate investment capacity in AI, if it is to be used as tool to manage health challenges. He nevertheless underlined the steps Makerere has undertaken to close the gaps by hosting units such as the Infectious Diseases Institute (IDI), AI and Health Lab, Innovation Pod, while working with various partners.

Prof. Buyinza Mukadasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi.

“We want to renew our commitment that we shall continue to translate our research findings into service delivery and products that improve the livelihoods of our people,” pledged Prof. Buyinza, who also noted that this will be undertaken within institutional ethical guidelines and policies, bolstered by good practices and recommendations arising from the conference.

Taking cognizance of contributions of various partners to strides made so far, the Permanent Secretary Ministry of ICT and National Guidance, Dr. Aminah Zawedde who was represented by Mr. Ambrose Ruyooka, the Ministry’s Head of Department of Research and Development, thanked the Makerere University AI Health Lab, IDI, Health AI for All Network, the Research and Innovation Fund, the African Population and Health Research Centre, and the Mastercard Foundation for convening the second edition of the conference.

“This year’s theme aligns perfectly with Uganda’s digital transformation vision. It reminds us that while innovation is powerful, true progress lies in ensuring it is equitable, ethical, locally relevant, and accessible to all” read Dr. Zawedde’s remarks.

Mr. Ambrose Ruyooka. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Mr. Ambrose Ruyooka.

She noted that when used responsibly, AI empowers healthcare workers to do more with greater precision and efficiency while extending services to under-served communities, essentially amplifying their impact whilst preserving the essential human touch that defines care. Dr. Zawedde reiterated the Government of Uganda’s commitment to positioning AI as a catalyst for national development and improved service delivery through the national AI governance framework. “By the end of 2025, we expect to reach a decision on whether to adopt a comprehensive AI policy or a flexible, sector-led regulatory approach.”

Referring to projects already underway at the College of Computing and Information Sciences (CoCIS), the Principal, Prof. Tonny Oyana underscored the great promise AI holds for not only improving affordability but also diagnosis of disease. He nevertheless called for targeted investment in data centres so as to build the required capacity to process the large amount of data that AI thrives on.

Prof. Tonny Oyana. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Tonny Oyana.

The Executive Director IDI and conference Co-Chair, Dr. Andrew Kambugu described the conference timing as “impeccable”. Citing a recently convened conference on Communicable and Non-Communicable Diseases that discussed Universal Health Coverage, he shared “there are people in this country who are one step away from disaster because of health.”

He therefore paid tribute to his conference Co-Chair, Dr. Rose Nakasi, whose AI-automation work with the light microscope, one of game-changing inventions in human medicine to-date, has improved precision, accuracy and efficiency in diagnosis of malaria, tuberculosis and cancer in healthcare facilities. Dr. Kambugu therefore urged his audience to always be eager to learn about the capabilities game changing tools such as AlphaFold.

Dr. Andrew Kambugu. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Andrew Kambugu.

“Our African Centre of Excellence in Bioinformatics & Data Intensive Science (ACE) in collaboration with CoCIS has been one of the first trainers of AlphaFold in Africa” remarked Dr. Kambugu. He added that the to ensure inclusive training ACE has attracted funding to support the She Data Science (SHEDS) project, an initiative that offers MSc and PhD fellowships to Ugandan women in the fields of data science and bioinformatics, with a strong emphasis on health data.

Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left). 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left).

How Ocular is shaping healthcare

Conference Co-Chair and Principal Investigator of Ocular, Dr. Rose Nakasi noted that their project that aims at empowering healthcare professionals with AI-powered microscopy was motivated by the fact that wrong diagnoses have a cascading effect on prescription, treatment, recommendation and surveillance services. “Where health practitioners have been taking 30 minutes or more to diagnose malaria, and days to diagnose cancers, we are slashing down that time to literally 5 seconds to diagnose and make a recommendation.” She added.

Dr. Nakasi added that beyond diagnosis, the Ocular project is supporting the Ministry of Health with more precise surveillance and monitoring of diseases by quicker augmentation of information for faster roll-out of interventions as opposed to current weekly or monthly reporting period required by the Digital Health Information System (DHIS 2).

Dr. Rose Nakasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Rose Nakasi.

“The beauty about AI is that it has the capability not to just learn with one dataset but also provide insights on different pieces of data – for diseases such as malaria where climate has an effect, we want to integrate climate datasets and seasonality aspects so that interventions by Government are timely and targeted to specific locations.”

The Ocular project exhibition setup. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
The Ocular project exhibition setup.

Beyond the plenary sessions, the 2nd AI in Health Africa Conference will feature abstract presentations, a Makerere AI Health Lab Showcase, Breakout Sessions, Workshops, Masterclasses and a hackathon for prototypes developed during the conference. Please see downloads for a detailed concept and programme.

Mark Wamai

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Health

JASH2025 opens with call for renewed commitment to prevention, innovation and partnership

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Dignitaries pose for a group photo at the JASH2025 opening ceremony on 5th November 2025. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.

The 19th edition of the Joint Annual Scientific Health Conference (JASH) jointly held with the Inaugural National Communicable and Non-Communicable Diseases Conference (NACNDC) was officially opened by Hon. Jane Ruth Aceng Ocero, Minister for Health on 5th November 2025. The Minister called for renewed commitment to prevention, innovation, and partnership if Uganda is to end preventable communicable and non-communicable diseases by 2030.

The Conference themed, ‘Unified Action Against Communicable and Non-Communicable Diseases’ held at Speke Resort Munyonyo, Kampala, Uganda from 3rd to 7th November 2025 is organised by Makerere University College of Health Sciences (MakCHS), Makerere University School of Public Health (MakSPH) and Ministry of Health (MoH). The convening brings together over 500 delegates from government, academia, civil society, development partners, and the private sector. 

Hon. Dr. Jane Ruth Aceng Ocero Minister of Health who was the Chief Guest, officially opened the conference. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Hon. Dr. Jane Ruth Aceng Ocero Minister of Health who was the Chief Guest, officially opened the conference.

Highlighting the areas where commendable progress has been made including: full childhood vaccination from 37% in 2000 to 68% in 2022, reduced child stunting from 45% to 26%, increased life expectancy from 45 years in 1986 to 68 years in 2022, strong HIV control among others. The Minister also noted that Uganda continues to grapple with challenges like sub-optimal uptake of new vaccination anti-gens fueled by misinformation, myths and rumors; geographical disparities in access to quality health services; 29.1% of Ugandans being obese or overweight signaling the risk to develop NCDs like hypertension and diabetes.

‘To address the challenges, we must: strengthen our health systems, ensuring that services are accessible, equitable, and of high quality; enhance our community engagement and empowerment, enabling individuals to make informed health decisions, providing informationm Foster partnerships across sectors and actors to create a supportive environment for elimination of communicable and non-communicable diseases’, the Minister said.

She further said, ‘unified action against communicable and non-communicable as theme of this conference calls for integrated, people-centred approaches to prevention and care’. She emphasized that disease control is not the responsibility of the health sector alone, it requires collaboration with education, local government, water and sanitation, transport, and private sectors.

PS-MoH Dr. Diana Atwine. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
PS-MoH Dr. Diana Atwine.

In her remarks to the congregation, Dr. Diana Atwine, Permanent Secretary-MoH commended the organisers for successfully organizing the conference. She noted that the inaugural NACNDC marks a milestone for the health sector in addressing the rising double disease burden of communicable and non-communicable among the Ugandan population.

‘The theme aligns with our new strategic direction that emphasises collaboration amid declining external funding, therefore, let us continue to plan, invest, and be accountable together’, Dr. Atwine said.

She noted the multiple achievements and remaining challenges of the health sector underscoring the priorities of MoH including: upgrading key hospitals, expanding blood banks, recruitment of specialised staff, equipping regional facilities, scaling-up digitization, and strengthening immunization and community health systems.

The Permanent Secretary expressed her gratitude for the work of the organizing committee, partners and participants for making the conference a success. She called for sustained momentum of collaboration and innovation reiterating commitment of the MoH in supporting the platform created from this conference.

She re-echoed the role of academia in the unified action, ‘Academia we depend on you for innovative ways. Your research should answer our burning questions to solve our problems’.

Prof. Bruce Kirenga, Principal MakCHS. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Bruce Kirenga, Principal MakCHS.

Prof. Bruce Kirenga, Principal-MakCHS appealed to government to consume products from training institutions especially nurses and other allied health professionals noting that currently 40,000 nurses are not employed, many turning to odd jobs. He thanked government for the gains in science and enabling the partnerships leading to such meetings and dialogue on solutions to national challenges.

Prof. Kirenga reminded participants that MakCHS is celebrating 100 years with an upcoming Alumni Dinner to be held on 12th December 2025, he invited all well-wishers to attend calling for their support as we fundraise to refurbish infrastructure at the college and build new facilities amidst the increased number of learners.

Prof. Rhoda Wanyenze, Dean MakSPH. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Rhoda Wanyenze, Dean MakSPH.

Professor Rhoda Wanyenze, Dean MakSPH expressed commitment of the university and researchers to continue to serve in this space by providing data to inform evidence-based policy making. ‘Rather than describe existing problems we commit to offer innovative solutions to the problems and train and produce a workforce that is aligned to requirements of where they serve’ she added.

Delivering the speech of Professor Sarah Ssali, Deputy Vice Chancellor-Academic Affairs, Makerere University, Professor Robert Wamala, Director-Research & Innovations said ‘Makerere University is honored to co-host the conference with Ministry of Health. This partnership shows that research, policy and practice must move together to solve challenges of our population. Let this conference not be another meeting but a beginning for sustained health dialogue’.

Prof. Wamala Robert represented DVC/AA. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Wamala Robert represented DVC/AA.

Delivering the conference objectives at the conference, Dr. David Musoke, Associate Professor at MakSPH and Conference Co-Chair, underscored the need for integrated, evidence-driven approaches to Uganda’s evolving health challenges. 

He noted that the joint conference, co-convened by the Ministry of Health, MakSPH, and partners, marks a pivotal step in aligning research, policy, and community practice to strengthen the country’s health systems.

Dignitaries pose for a group photo with stakeholders. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Dignitaries pose for a group photo with stakeholders.

The conference that began on 3rd November with pre-conference sessions on Mental Health, Paediatric Healthcare, among others continues till 7th November with participants continuing to dialogue on how to build a resilient health system for Uganda within the changing funding landscape.

Zaam Ssali

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