Veterinary & Biosecurity
Makerere University Hosts Stakeholders Workshop on One Health approach to understanding Climate Change and Zoonoses
By Joseph Odoi
On January 30-31, 2025, Makerere University in partnership with Glasgow, UK and University of Stockholm, Sweden with support from Europe’s CIVIS University Alliance, organized a multi-disciplinary workshop at Kabira Country Club, Kampala, Uganda entitled “One Health and Diagnosing Zoonoses – Understanding the Importance of Climate Change in Disease Prevalence.” The event brought together a diverse group of stakeholders, including academicians, researchers, and practitioners, to collaborate on addressing public health challenges at the intersection of human, animal, and environmental health.
The workshop was organized and officially opened by Associate Professor Lawrence Mugisha from the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University alongside Professor Jonathan Cooper from the University of Glasgow, who led the CIVIS Alliance team to Uganda.
In his opening address, Prof. Mugisha welcomed participants and outlined the key objectives of the workshop. He noted that the primary aim of the workshop was to build new pathways for knowledge exchange and strengthen One Health capabilities within Uganda and East Africa in order to develop a better understanding of the role of climate change in disease dynamics (including zoonoses) in humans and animal health and their wellbeing.
Furthermore, the workshop sought to explore the regional links between zoonotic disease prevalence and climate change by using appropriate digital tools/systems that will, in future, have the potential to be used more widely in Sub-Saharan Africa.
On the impact of Climate Change in Disease Prevalence, Professor Mugisha noted that the World Bank, the World Health Organization (WHO) and World Organisation for Animal Health (WOAH) have all warned around the need to better understand the harmful effects of climate change on health and disease, especially in low-and-middle-income-countries with such effects readily seen with Sub-Saharan Africa suffering some of the worst impacts.
‘’Uganda is also considered as a ‘hot spot’ for emerging and re-emerging infectious disease epidemics. The country has experienced several epidemics including; Ebola, Marburg, Plague, Rift Valley Fever, Yellow fever and Crimean Congo hemorrhagic fever. ‘’Many of these public health challenges arise from the interaction between humans-animals-environment and require a One Health approach as a collaborative effort of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals, plants and the environment.’’ added Professor Mugisha.
In his remarks, Professor Jonathan Cooper from the University of Glasgow acknowledged participants and provided a brief background on the CIVIC University Alliance. He stated that under CIVIS, multiple universities collaborate to offer joint learning pathways, research opportunities, and diverse degree programs, creating a dynamic network where students and academics can move freely between institutions. Through this collaboration, they work together to address societal challenges, including One Health and climate change, while also developing real-world solutions. He also commended the collaborative efforts of Makerere University, particularly those of Professor Lawrence Mugisha, in working across multiple disciplines at local, national, and global levels to achieve optimal health for people, animals, plants, and the environment.
Prof. Mugisha delivered a keynote address on climate change and human health and highlighted how climate change is causing unprecedented threats to human health, driving emergence of new infectious diseases and exacerbating the existing ones in addition to fueling frequent occurrence of severe natural catastrophes like floods, hurricanes and wildfires. He reported as per World Economic Forum Report of 2024, that climate change is projected by 2050 to cause additional 14.5 million deaths and $12.5 trillion in economic losses worldwide. He called upon all stakeholders to act together through research, innovations and public directed interventions to reverse the potential impact of climate change. He provided examples of different research consortiums working together to contribute to finding solutions to address the impacts of climate on health of humans, animals and entire ecosystem. Highlighted Projects include DIDIDA-Improving disease diagnosis in Africa (Home – Didida), PREPARE4VBDS— A Cross-Disciplinary Alliance to Identify, PREdict and prePARE for Emerging Vector-Borne Diseases (prepare4vbd.eu) and recently funded DIDIDI- development of advanced, low-cost and deployable digital dashboards and diagnostics to understand how changes in climate are affecting the dynamics of soil-transmitted helminth (STH) and schistosomiasis in underserved rural community settings in sub-Saharan Africa
Dr. Frederick Monje, a focal person for the One Health Platform from the Ministry of Agriculture, Animal Industry and Fisheries (MAAIF), provided a brief background of the National One Health Platform of Uganda. He stated that the platform was established in 2016 to serve as a multi-sectoral coordination mechanism aimed at addressing public health threats arising from the interactions between humans, animals, and the environment.
Dr. Monje emphasized that the National One Health Platform in Uganda plays a critical role in surveillance, early detection, and rapid response to outbreaks through collaborations with district health teams, universities, and research institutions. He noted, “One Health is one of the ways to prevent the next pandemic. We need to do a lot of preparedness to prevent cross-cutting public health threats from coming to us. We have developed a number of training and partnerships with universities and many stakeholders to achieve the One Health objective.”
In his presentation, Mr. Monje also cited the World Bank’s report, highlighting that globally, zoonotic diseases sicken 2.4 billion people annually, kill 2.2 million, and affect more than 1 in 7 livestock. The direct economic costs of zoonotic diseases are estimated at 20 billion dollars per year. He pointed out that Uganda, due to its proximity to the Congo Basin and other hotspots, faces significant public health threats from zoonotic diseases.
Mr. Monje further emphasized that the platform’s impact is evident in its district-level One Health teams, which have strengthened Uganda’s pandemic preparedness and response to zoonotic diseases such as Ebola, Rift Valley Fever, and anthrax. He reiterated that One Health is critical to preventing future pandemics, requiring continuous preparedness, collaboration, and policy development to safeguard public health.
In her presentation, Ms. Patricia Nyinguro- Principal Meteorologist at the Kenya Meteorological Department revealed that there is rising temperatures in Kenya, showing an increasing trend since 1961, particularly in semi-arid regions. Despite this, she noted that public perception of heatwaves is low yet rising temperatures are key drivers of heat-related mortality, morbidity, and infectious diseases.
Moving forward, Ms. Patricia emphasized the importance of interdisciplinary collaboration in developing heat health action plans and called for the development of indicators to measure progress in climate change adaptation.
In a digital technologies session, Dr. Xin Guo from the University of Glasgow shared insights on mobile health platforms for diagnostics, including demonstrations of relevant applications. He showed how apps can help diagnose diseases, especially zoonotic ones, and improve healthcare, especially in areas that need better disease tracking and response.
Participants engaged in discussions on zoonoses, its impact, and the importance of the One Health approach. Key questions explored included: What are zoonoses? Why is One Health crucial? Who are the stakeholders involved, and how can zoonoses be effectively addressed?
Using the Double Diamond Methodology, participants in group discussions also identified the most pressing challenges that climate change poses or will pose on zoonoses, potential solutions, and the reasons why these solutions aren’t being implemented yet.
Key outcomes from the engagement included the drafting of a policy brief outline, which will guide future initiatives aimed at tackling public health threats.
The workshop also tackled important issues such as data interoperability, data ownership and management, and ethics and privacy. These topics were thoroughly explored during structured discussions, with a particular focus during the Early Career Researcher (ECR) session.
Dr. Paul Mbanka, Assistant Commissioner of Health Services, outlined the Ministry of Health’s commitment to addressing Zoonoses related cases citing presence of an incident management system, which includes an SMS-based mechanism for reporting diseases to the emergency response center. Upon detection of an alert, the information is verified, samples are collected, and if confirmed, a response is initiated. In terms of areas for improvement, Dr. Mbanka acknowledged the challenge of information sharing across various sectors. When asked about Data sharing by workshop participants, He also stated that the Ministry of Health is open to sharing data with researchers, provided it supports the Ministry’s goals
The two-day workshop concluded with an emphasis on the critical need for continued collaboration in the One Health sector. Participants, including Researchers, Academicians, PhD and Master’s students from Makerere University, and Uganda and Kenya registered students at Glasgow University made presentations and also engaged in strategic discussions on tackling zoonotic diseases, climate change, and the integration of digital innovations in health data management.
To conclude the workshop, Prof. Lawrence Mugisha, Professors Julien Reboud and Jon Cooper of the Makerere University and University of Glasgow respectively expressed their appreciation to all participants for the insightful presentations, discussions and emphasized the importance of ongoing partnerships across human, animal, and environmental health sectors.
Veterinary & Biosecurity
Experts Discuss Climate-Smart Agriculture and Livestock Feed Innovations in Uganda
Leading agricultural experts and stakeholders convened for a high-level roundtable discussion on climate-smart initiatives and livestock feed innovations in Uganda. Hosted at the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, the event brought together scientists, policymakers, and entrepreneurs to exchange ideas on sustainable agriculture and the future of livestock feeding.
In the opening remarks, Dr. Dorothy Nampanzira, the head of the Department of Livestock and Industrial Resources Department at CoVAB welcomed participants and expressed deep appreciation for their engagement, emphasizing the significance of such discussions in driving meaningful change. She acknowledged the progress made in climate-smart agriculture while stressing the need for thorough documentation and continued evaluation to ensure that all achievements are fully leveraged for future impact.
The Livestock Climate Smart Technologies Round Table Discussion is one of the activities organized under the four-year collaborative research project namely; Building Capacity for Innovation and Advancement of Climate Smart Agriculture in East and Southern Africa (CICSA-E&SA). One of its objectives is to develop a Climate Smart Agriculture platform that includes key stakeholders engaged and interested in key activities and initiatives that promote Climate Smart Agriculture practices and technologies to share experiences and lessons to further the resilience of farmers among others. The project is run by a project implementation committee comprised of Prof. John Tabuti, Prof. Josephine Esaete, Prof. Vincent Muwanika, and Dr. Dorothy Nampanzira.
Participants were drawn from key units including the Food and Agricultural Organization (FAO), the Ministry of Agriculture, Animal Resources and Fisheries (MAAIF), the College of Agricultural and Environmental Sciences, (CAES), College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) among others and they included scientists and PhD students. Throughout the session, experts explored various innovative farming strategies, including improved manure management, the use of repurposed agricultural byproducts, and alternative feeding approaches such as insect-based feed and probiotics. The discussions highlighted the necessity of research-driven solutions to maximize efficiency and ensure safe adoption of these techniques.
With Uganda’s livestock industry expanding rapidly, concerns were raised about gaps in technical knowledge among farmers, particularly as modern farming practices evolve. Participants emphasized the importance of bridging this gap through better documentation, sensitization programs, and closer collaboration between researchers and farmers.
The discussions made some future projections based on available research and experiences drawn from elsewhere which projections indicate that Uganda will need to significantly increase its milk and meat production by 2050 to meet the growing demand. Experts underscored the importance of predictive models and data-driven research to assess feed availability, considering factors such as rising carbon dioxide levels that could affect grass protein content, which is a major component of livestock diets.
The discussions concluded with recommendations to strengthen stakeholder cooperation, enhance information-sharing efforts, and revive research dissemination initiatives. Dr. Nampanzira encouraged continued engagement, urging participants to contribute to future projects and explore funding opportunities to support similar discussions. This roundtable serves as a critical step toward sustainable agriculture, ensuring Uganda remains prepared to meet evolving climate and food security challenges.
During the discussions, participants reflected on various strategies farmers are adopting to cope with climate change, including innovative manure management and repurposing agricultural byproducts. While some methods have traditional roots, enhancing efficiency through research and technology was emphasized as crucial for long-term sustainability.
A key topic was the adoption of alternative feeding strategies such as insect-based feed, blood meal, and probiotics. Scientists highlighted the need for further research to validate these methods, ensuring they meet safety standards and are viable for widespread use. In addition, participants explored high-protein forage options, such as elephant grass from China, which boasts a 19% protein content. Experts warned, however, of the risks associated with introducing non-native plant species, stressing the importance of scientific guidance in agricultural innovations.
Another challenge addressed was the knowledge gap between farmers and researchers. With an increasing number of elite farmers investing in modern practices, the lack of technical oversight could lead to long-term negative effects. Stakeholders called for better documentation of successful farming methods and increased efforts in farmer education.
Discussions also touched on Uganda’s future food security, with projections indicating a 200% increase in milk demand and a 300% rise in meat production by 2050. Experts stressed the importance of data-driven research to assess feed availability and predict future needs, noting that rising carbon dioxide levels could diminish grass protein content, which was a major concern for livestock-dependent industries.
The event concluded with recommendations to strengthen multi-stakeholder engagement and revive research dissemination initiatives. The Ministry of Agriculture, Animal Industry and Fisheries (MAAIF) was urged to develop regulatory frameworks, particularly on animal feed policy, to support sustainable livestock farming.
In her closing remarks, Dr. Nampanzira praised the participants for their dedication and called for continued collaboration in securing funding for future discussions. She encouraged experts to contribute to extension grants and policy formulation, recognizing the significance of collective action in addressing Uganda’s agricultural challenges.
Veterinary & Biosecurity
PREPARE4VBD Project Holds Final Workshop in Uganda; A Landmark in Vector-Borne Disease Preparedness
By Joseph Odoi
The final dissemination workshop of the EU-funded project: A Cross-Disciplinary Alliance to Identify, PREdict, and PrePARe for Emerging Vector-Borne Diseases (PREPARE4VBDs) was successfully held from May 5th to 8th, 2025 at Best Western Premier Garden Hotel, Entebbe, Uganda, marking the culmination of a five-year, cross-continental research effort addressing vector-borne diseases in the era of climate change and globalization.
The hybrid event attracted over 80 participants, including researchers, policymakers, health practitioners, veterinarians, early-career scientists, and students from Africa and Europe. The workshop featured two key sessions with; one at Best Western Premier Garden Hotel, Entebbe, and another at the Centre for Biosecurity, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University.
In his opening remarks, Professor Lawrence Mugisha (Uganda’s Co-Principal Investigator from CoVAB, Makerere University), officially welcomed all stakeholders and highlighted that the purpose of the workshop was to share research findings and engage stakeholders as the project wraps up. The project commenced in September 2021 and will end in August 2025.
Prof. Mugisha noted that the overall aim of PREPARE4VBD is to strengthen preparedness in Africa and Europe for emerging zoonotic vector-borne diseases, especially in an era of climate change and increasing global interconnectedness by (a) Creating a broad, and conceptual knowledge about vector-borne disease emergence and responses to climate change that reaches beyond specific diseases, vector species, borders or scientific disciplines (b)Improving prediction and preparedness in Africa and Europe for zoonotic vector-borne diseases transmitted by mosquitoes, ticks and freshwater snails to livestock and humans under climate change and globalization.
In a project overview, the PREPARE4VBD Principal Investigator, Professor Anna-Sofie Stensgaard from the Department of Veterinary and Animal Sciences at the University of Copenhagen, noted that vector-borne diseases are on the move, accounting for 17% of all infectious diseases and causing 700,000 deaths across the globe each year. She emphasized that zoonotics can’t be isolated as a human or animal health issue.
“The problem is growing and they are on the move,” she said, pointing to increased outbreaks of Rift Valley Fever, Dengue, West Nile, Chikungunya, Fasciolosis, and Schistosomiasis.
Because of this, she noted that the project thought of the need for cross-cutting and in-depth knowledge to improve surveillance and build capacity for early detection, as vector-borne diseases respect no borders. This, she explained, justified the formation of a multidisciplinary team consisting of 10 complementary partner institutions in Europe and Africa.
In terms of approach, she noted that the project used a proactive approach that focuses on addressing VBDs at a lower level, rather than the usual reactive approach that tackles diseases after they present themselves in large numbers.
More specifically, Professor Anna-Sofie noted that PREPARE4VBD focused on four thematic areas aimed at
A) Building knowledge through baseline data collection of neglected tick-, mosquito-, and snail-borne VBDs of importance for animal and human health in endemic African countries.
B) Assessing their capacity to adapt and spread to new areas using a holo-genomics approach and state-of-the-art climate change impact modelling.
C) Developing novel, sensitive diagnostic tools and model-based surveillance for rapid VBD discovery and early warning.
D) Strengthening the capacity for detection and surveillance of the targeted VBDs through training, effective communication, and dissemination of freely available data.
As part of project activities, Professor Anna-Sofie shared that the project conducted
- Training of 4 MSc students and 11 PhD fellows, as well as early-career researcher summer schools in Uganda and Kenya.
- Engaging fellows in the poster sessions and technical workshops, such as molecular diagnostics and VBD modeling.
- Promotion of transdisciplinary collaboration and knowledge exchange among partners across Africa and Europe.
In terms of key project achievements, she noted the project was able to achieve the following
- The development of a new AI-assisted Mini-FLOTAC microscope model.
- Creation of a model for Rift Valley Fever transmission and analysis of climate change impacts on snail-borne diseases.
- Discovery of an Ixodes tick species in Kenya, which was previously only known in Europe.
- Large-scale vector-snail warming experiments conducted across different climates, from South Africa to Denmark.
- Creation of a Global Vector Database (GVD) for centralized vector data collection.
- Development of non-invasive diagnostic tools, including PCR tools for pathogen detection in livestock blood/tick fluids, environmental DNA methods for liver fluke detection, and establishment of standard operating procedures (SOPs) and training videos, all publicly accessible online.
Research Highlights in Uganda
In terms of consortium research highlights from the VBD project in Uganda, Adriko Moses from the Ministry of Health shared a multi-stakeholder approach to mitigate risks of liver fluke infections, a zoonotic disease affecting humans and animals.
Six districts near lake basins were studied: Hoima, Buliisa, Apac, Lira, Jinja, and Mayuge. The study involved 300 human samples, with 2 positive cases identified. Findings also highlighted damaged livers in slaughtered animals.
To address this trend in Uganda, the following policy recommendations were made from the study
Policy Recommendations for Control and Prevention of Liver Fluke Disease in Uganda
- Strengthen meat inspection policy in Uganda, including livestock testing before slaughter and enhanced meat testing protocols.
- Promote vegetable hygiene to control zoonotic fascioliasis—a parasitic infection transmitted through contaminated food.
- Scale up veterinary interventions in livestock through collaboration between farmers and veterinary services.
- Establish surveillance systems to monitor infections among livestock.
- Increase community engagement to improve health education and foster community-led health initiatives.
Remarks from Government and Academia
Dr. Peter Wanyama, representing the Commissioner for Ministry of Agriculture, Animal Industry and Fisheries (MAAIF), commended the consortium for selecting Uganda and recognized the threat of VBDs to both animal and human health, as well as national development. He noted the challenge of tick resistance, and that MAAIF is constructing 69 diagnostic laboratories to address emerging vector-borne threats. He emphasized the need for local knowledge, effective communication, and knowledge translation.
Dr. Allan Muruta, Guest of Honour and Commissioner for Animal Health Services at the Ministry of Health, welcomed the multidisciplinary team to Uganda on behalf of the Minister of State for Primary Health Care.
He thanked the consortium for a well-done multidisciplinary effort addressing the growing challenge of vector-borne diseases in Africa. As a technical officer in surveillance, Dr. Muruta appreciated the project’s clear planning and timely execution.
“Africa is endemic to zoonotic diseases but allow me to share what the Ministry of Health has done. Our Integrated Surveillance Department has set up coordinated responses to several public health issues,” he shared.
He welcomed the findings and policy briefs developed through the research, noting they are relevant, science-based, and practical. He said the Ministry of Health has clear structures for handling policy issues and committed to engaging further to ensure policy uptake and action.
“All the policy briefs are feasible, new, and based on up-to-date science. The Ministry will follow through to see these policies implemented.”
He further noted that Uganda already has a functional One Health platform bringing together directors from health, water, and wildlife sectors. However, he emphasized the need to strengthen data sharing across the sub-national level. The Ministry, he said, is engaging with different sectors to make this happen.
Dr. Muruta reaffirmed the Ministry of Health’s openness to more collaboration in tackling zoonotic diseases and strengthening the One Health approach.
Prof. Frank Mwine, Principal of CoVAB, Makerere University, welcomed participants and applauded collaborative efforts in addressing vector-borne diseases.
In his remarks at Makerere University, Prof. Frank Mwine welcomed the diverse participants and thanked Prof. Lawrence Mugisha for his proven coordination and mobilization around One Health. He acknowledged the growing threats posed by climate change and emphasized the interconnectedness of ecosystems citing how birds migrate from Europe to Africa—as a reason for cross-border collaboration.
He commended the PREPARE4VBD project team for their unique research and innovations aimed at addressing vector-borne diseases and appreciated the European Union’s Horizon 2020 research and innovation programme for supporting such a critical initiative.
Looking ahead, Prof. Mwine stressed the importance of training the next generation to strengthen preparedness and response efforts in the future.
In a cross-country experience-sharing session involving Côte d’Ivoire, Uganda, and South Africa, coordinated by Prof. Moses J. Chimbari (South Africa), participants agreed on the urgent need to integrate One Health into university curricula and bring together diverse disciplines to address vector-borne diseases caused by climate change and other complex factors.
In this engagement, there were a number of panel discussions revolving around translating policy recommendations into practical actions for long-term impact. Prof Lawrence Mugisha at this engagement announced that another dissemination on VBDs project outcomes will be held specifically for Students who were doing exams at the time of the Project dissemination
Workshop Highlights
Key research outcomes were presented, including the development of a Global Vector Database (GVD), AI-assisted diagnostic tools, and predictive climate-disease models.
The Entebbe session hosted high-level stakeholders, including representatives from the Ministries of Health and Agriculture, NGOs, and international research bodies. Discussions emphasized the importance of translating research into policy and action.
For outreach and dissemination, thirteen policy briefs were shared, alongside posters, infopacks, risk maps, peer-reviewed publications, newsletters, and fellow-driven blog posts all aimed at sustaining knowledge exchange beyond the project lifespan.
Notable to mention was the development of a knowledge co-production model under the project, titled “Knowledge Co-Construction in Stakeholder Engagement Workshops in Health Research” by Kathrin Heitz Tokpa, Lawrence Mugisha, Moses Chimbari, and Bassirou Bonfoh.
The project has notably enhanced Africa Europe scientific cooperation and empowered local institutions with tools and training to detect, track, and control emerging diseases.
About the Project
PREPARE4VBD is a multi-disciplinary consortium that brings together 10 university and ministerial partners from 5 African and 3 European countries, united to address a future with increasingly changing global patterns of zoonotic vector-borne diseases through a holistic, pro-active approach that reaches beyond specific diseases, vector species, borders or scientific disciplines.
Project partners included; Makerere University, Sokoine University of Agriculture, University of KwaZulu-Natal, University of Naples Federico II, Swiss TPH, University of Bern, ICIPE, Uganda’s Vector Control Division, Centre Suisse de Recherches Scientifiques, and Tanzania’s NIMR.
The project is part of Horizon 2020’s research and innovation actions (Grant agreement No. 101000365: https://cordis.europa.eu/project/id/101000365) and is coordinated by the University of Copenhagen’s GLOBE Institute and Department of Veterinary and Animal Sciences.
To read more about the project, visit the PREPARE4VBD website (www.prepare4vbd.eu), which offers key resources on vector-borne disease preparedness, including open-access tools, training materials, and research outputs to support continuous capacity building.
Veterinary & Biosecurity
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