Veterinary & Biosecurity
Uganda Commemorates One Health Day with a call for a Multi-Sectoral Approach to address emerging health threats
Published
2 years agoon
By
Mak Editor
By Joseph Odoi
On 3rd November 2022, Uganda joined the rest of the world in celebrating One Health Day. This year marks the seventh annual One Health Day, a global campaign that celebrates and brings attention to the need for a One Health approach to address shared health threats at the human-animal-environment interface.
One Health Day is an initiative that gives One Health advocates and practitioners around the world a powerful voice for moving beyond provincial approaches to emerging zoonotic infectious diseases, antimicrobial resistance, climate change, environmental pollution, food safety, comparative/ translational medicine and many other problems, to a holistic, One Health, way of thinking and acting for the benefit of all living creatures.
While giving a keynote speech at Presidential Hall in Kampala under the theme “Our Planet, Our Health” at the Office of the President in Kampala, Dr. Lawrence Mugisha, an Associate Professor at Makerere University College of Veterinary Medicine, Animal Resources and Bio-Security (CoVAB) in a special way welcomed participants to the One-Health day celebrations. He noted that there’s urgent need for all sectors to work together if emerging and re-emerging infectious diseases and other public health threats are to be addressed.
“The challenges we face today whether health-related like emerging and re-emerging infectious diseases or public disasters like flooding, drought among others are complex, cross-cutting and cross different borders requiring one health approach which is multidisciplinary that facilitates collaboration, coordination and communication among different professionals/disciplines to address the public health events quickly. This helps to quickly identify appropriate interventions timely and use available resources effectively,”

Citing WHO data, Professor Mugisha noted AMR one of the emerging public health challenges which if left unchecked will contribute to 10 million deaths per year
To address these challenges, Prof.Mugisha recommended the following
- Raising public awareness about AMR and AMU
- Promoting water, hygiene and sanitation
- Enhanced AMR/AMU Surveillance in humans, animals and environment
- Investing in human capital for innovative research in vaccines and alternative therapeutic approaches like herbal use for the replacement of Antibiotic use.
In her presentation titled; Progress of Implementation of the anti-microbial resistance national action plan, Dr. Hellen Byomire Ndagije from National Drug Authority emphasized the importance of raising awareness to combat anti-microbial resistance adding that national drug authority has been holding Meetings to raise awareness of antimicrobial stewardship (AMS) and antimicrobial resistance (AMR) among health workers in pharmacies, and drug shops both human and animal medicine use

As part of capacity building to address AMR, she supported strengthening the Medicine Therapeutic Committees (MTCs) in regional referral hospitals with logistical support and technical training on rational medicine use and pharmacovigilance. In terms of antibiotics demand, she noted Uganda currently imports over 50,000 kilograms which should call for close vigilance.
To promote optimal access and use of antimicrobials, she recommended regular and risk-based testing of imported antimicrobials and medical equipment to assure their quality. She emphasized the need for good distribution practice standards to guarantee that antimicrobials are restored and dispensed in a way that does not compromise quality or efficacy. She said there was need to promote good manufacturing practices (GMP) inspections for both foreign and local drug manufacturers to ensure compliance to quality standards of manufacture, in addition to enforcing compliance monitoring and support supervision of human and veterinary drug outlets to ensure compliance to drug regulatory requirements.
As a way forward, she made recommendations that included the strengthening of stakeholder engagement, awareness, training and collaboration. The need for improved access to quality, safe and efficacious antimicrobials was emphasized in addition to strengthening pharmacovigilance: reporting ADE (AMR surveillance)
Dr. Ndadije stressed the need to promote rational use of drugs as well as investing in research and innovations
In her presentation, Dr. Lydia Nakiire under the Project titled 7-1-7 timeliness at Infectious Diseases Institute, Global Health Security Program said the Ministry of Health conducted a pilot study, ‘To Save Lives’ through Infectious Diseases Institute to identify bottlenecks causing delays in detection, notification and response.
During the study, she said, it was observed that application of One Health during responses to public health emergencies was one of the major enablers for timely initiation of early response. ‘’Recent outbreaks like Ebola Sudan virus disease and COVID 19 make it necessary to review the lessons learnt from recent public health events, reevaluate approaches and develop frameworks to measure progress towards making the world safe from public health threats.
The 7-1-7 framework proposes timeliness matrix with defined targets; 7 days to suspected outbreak detection, 1 day for public health authorities to be notified and the investigation is initiated within 7days. The 7-1-7 metric can supplement existing capacity measurements of the International Health Regulations (2005), including the Joint External Evaluation and Global Health Security Index’ explained Dr. Nakiire.

In his presentation on behalf of Dr. Immaculate Nabukenya, Senior Project Manager, NAPHS A-Team Uganda Herbert Bakiika shared the progress of Implementation of the Uganda National Action Plan for Health Security (NAPHS) and 2022 Operational Plan.

He noted there is progress in the following as mechanism of addressing AMR, and that the guidelines for mandatory license were drafted, but not approved. He further said that decentralizing One Health in 50 districts by 2024 to strengthen coordination of surveillance and response to zoonotic diseases was underway. Uganda committed to achieving demonstrated capacity in at least 3 technical areas by 2024.
He said the other milestone was licensing of all laboratories across animal, human, food, nuclear and chemical sectors by 2024 to strengthen the national laboratory network. On how this will be achieved, she said government was to liaise with professional councils to license laboratories in line with basic Quality Management Services (QMS)
Dr. Jonathan Mayito from Uganda Fleming Fund highlighted Inadequate human resources in the microbiology laboratories, Irrational and overuse of antibiotics, Lack of AMR data sharing across one health sectors, Lack of structures response to the emerging AMR epidemic as some of the challenges that needed to be addressed.

Moving forward, he recommended streamlining the supply of microbiology supplies by National Medical Stores, Increase human resources allocation through public service commission, data sharing agreement to enable data sharing to inform strategies and above all creating a National Task Force to investigate and respond to AMR alerts/outbreaks.
The Food and Agriculture Organization of the United Nations (FAO)’s Country Director, Bessong Willington emphasized the importance of capacity building to support timely intervention when addressing disease outbreaks. He called upon different sectors to work collaboratively and in a multidisciplinary fashion under the One Health Approach.
In his remarks read by Dr. John Opolot, Dr. Henry Mwebesa congratulated participants for marking the one-health day. He that 61% of all existing human infections in the past decade have been zoonotic including Ebola, HIV, and influenza and that 80 % of pathogens could potentially be used for bio terrorism.
In addition, to effectively strengthen One Health initiatives in Uganda, the Ministry of Health has embarked on roll out of the third edition of the integrated disease surveillance and response in over seven health regions using One Health approaches. The ministry, he said, also piloted integrated (both animal and human) sample transportation from communities using the hub transportation network using One Health Approaches.
On the importance of a multi-sectoral approach towards addressing public health challenges, Dr. Mwebesa emphasized the importance of involving all state and non-state actors including civil society and the private sector in one-health programmes.

In terms of government commitment, Dr. Mwebesa noted that The Ministry of Health will continue to support the One Health initiative, and currently government is funding division of veterinary public health and zoonoses which is supporting decentralization of One Health in over 30 districts to strengthen multi-sectoral emergency preparedness at sub-national level.
On current outbreak of Ebola, Dr. Mwebesa said The ministry of health shall continue to engage the National One Health platform in the current epidemic and urged all stakeholders to observe standard operating procedures to prevent the spread of Ebola virus disease. He equally thanked development, Implementing Partners and private sector partners for the financial and technical support towards the One Health initiatives as long forward to prevention, detection and response to emerging public health emergencies in the country.
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Veterinary & Biosecurity
Makerere University Hosts Stakeholders Workshop on One Health approach to understanding Climate Change and Zoonoses
Published
3 weeks agoon
February 10, 2025By
Mak Editor
By Joseph Odoi
On January 30-31, 2025, Makerere University in partnership with Glasgow, UK and University of Stockholm, Sweden with support from Europe’s CIVIS University Alliance, organized a multi-disciplinary workshop at Kabira Country Club, Kampala, Uganda entitled “One Health and Diagnosing Zoonoses – Understanding the Importance of Climate Change in Disease Prevalence.” The event brought together a diverse group of stakeholders, including academicians, researchers, and practitioners, to collaborate on addressing public health challenges at the intersection of human, animal, and environmental health.
The workshop was organized and officially opened by Associate Professor Lawrence Mugisha from the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University alongside Professor Jonathan Cooper from the University of Glasgow, who led the CIVIS Alliance team to Uganda.
In his opening address, Prof. Mugisha welcomed participants and outlined the key objectives of the workshop. He noted that the primary aim of the workshop was to build new pathways for knowledge exchange and strengthen One Health capabilities within Uganda and East Africa in order to develop a better understanding of the role of climate change in disease dynamics (including zoonoses) in humans and animal health and their wellbeing.
Furthermore, the workshop sought to explore the regional links between zoonotic disease prevalence and climate change by using appropriate digital tools/systems that will, in future, have the potential to be used more widely in Sub-Saharan Africa.
On the impact of Climate Change in Disease Prevalence, Professor Mugisha noted that the World Bank, the World Health Organization (WHO) and World Organisation for Animal Health (WOAH) have all warned around the need to better understand the harmful effects of climate change on health and disease, especially in low-and-middle-income-countries with such effects readily seen with Sub-Saharan Africa suffering some of the worst impacts.
‘’Uganda is also considered as a ‘hot spot’ for emerging and re-emerging infectious disease epidemics. The country has experienced several epidemics including; Ebola, Marburg, Plague, Rift Valley Fever, Yellow fever and Crimean Congo hemorrhagic fever. ‘’Many of these public health challenges arise from the interaction between humans-animals-environment and require a One Health approach as a collaborative effort of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals, plants and the environment.’’ added Professor Mugisha.
In his remarks, Professor Jonathan Cooper from the University of Glasgow acknowledged participants and provided a brief background on the CIVIC University Alliance. He stated that under CIVIS, multiple universities collaborate to offer joint learning pathways, research opportunities, and diverse degree programs, creating a dynamic network where students and academics can move freely between institutions. Through this collaboration, they work together to address societal challenges, including One Health and climate change, while also developing real-world solutions. He also commended the collaborative efforts of Makerere University, particularly those of Professor Lawrence Mugisha, in working across multiple disciplines at local, national, and global levels to achieve optimal health for people, animals, plants, and the environment.
Prof. Mugisha delivered a keynote address on climate change and human health and highlighted how climate change is causing unprecedented threats to human health, driving emergence of new infectious diseases and exacerbating the existing ones in addition to fueling frequent occurrence of severe natural catastrophes like floods, hurricanes and wildfires. He reported as per World Economic Forum Report of 2024, that climate change is projected by 2050 to cause additional 14.5 million deaths and $12.5 trillion in economic losses worldwide. He called upon all stakeholders to act together through research, innovations and public directed interventions to reverse the potential impact of climate change. He provided examples of different research consortiums working together to contribute to finding solutions to address the impacts of climate on health of humans, animals and entire ecosystem. Highlighted Projects include DIDIDA-Improving disease diagnosis in Africa (Home – Didida), PREPARE4VBDS— A Cross-Disciplinary Alliance to Identify, PREdict and prePARE for Emerging Vector-Borne Diseases (prepare4vbd.eu) and recently funded DIDIDI- development of advanced, low-cost and deployable digital dashboards and diagnostics to understand how changes in climate are affecting the dynamics of soil-transmitted helminth (STH) and schistosomiasis in underserved rural community settings in sub-Saharan Africa
Dr. Frederick Monje, a focal person for the One Health Platform from the Ministry of Agriculture, Animal Industry and Fisheries (MAAIF), provided a brief background of the National One Health Platform of Uganda. He stated that the platform was established in 2016 to serve as a multi-sectoral coordination mechanism aimed at addressing public health threats arising from the interactions between humans, animals, and the environment.

Dr. Monje emphasized that the National One Health Platform in Uganda plays a critical role in surveillance, early detection, and rapid response to outbreaks through collaborations with district health teams, universities, and research institutions. He noted, “One Health is one of the ways to prevent the next pandemic. We need to do a lot of preparedness to prevent cross-cutting public health threats from coming to us. We have developed a number of training and partnerships with universities and many stakeholders to achieve the One Health objective.”
In his presentation, Mr. Monje also cited the World Bank’s report, highlighting that globally, zoonotic diseases sicken 2.4 billion people annually, kill 2.2 million, and affect more than 1 in 7 livestock. The direct economic costs of zoonotic diseases are estimated at 20 billion dollars per year. He pointed out that Uganda, due to its proximity to the Congo Basin and other hotspots, faces significant public health threats from zoonotic diseases.
Mr. Monje further emphasized that the platform’s impact is evident in its district-level One Health teams, which have strengthened Uganda’s pandemic preparedness and response to zoonotic diseases such as Ebola, Rift Valley Fever, and anthrax. He reiterated that One Health is critical to preventing future pandemics, requiring continuous preparedness, collaboration, and policy development to safeguard public health.
In her presentation, Ms. Patricia Nyinguro- Principal Meteorologist at the Kenya Meteorological Department revealed that there is rising temperatures in Kenya, showing an increasing trend since 1961, particularly in semi-arid regions. Despite this, she noted that public perception of heatwaves is low yet rising temperatures are key drivers of heat-related mortality, morbidity, and infectious diseases.

Moving forward, Ms. Patricia emphasized the importance of interdisciplinary collaboration in developing heat health action plans and called for the development of indicators to measure progress in climate change adaptation.
In a digital technologies session, Dr. Xin Guo from the University of Glasgow shared insights on mobile health platforms for diagnostics, including demonstrations of relevant applications. He showed how apps can help diagnose diseases, especially zoonotic ones, and improve healthcare, especially in areas that need better disease tracking and response.

Participants engaged in discussions on zoonoses, its impact, and the importance of the One Health approach. Key questions explored included: What are zoonoses? Why is One Health crucial? Who are the stakeholders involved, and how can zoonoses be effectively addressed?

Using the Double Diamond Methodology, participants in group discussions also identified the most pressing challenges that climate change poses or will pose on zoonoses, potential solutions, and the reasons why these solutions aren’t being implemented yet.
Key outcomes from the engagement included the drafting of a policy brief outline, which will guide future initiatives aimed at tackling public health threats.

The workshop also tackled important issues such as data interoperability, data ownership and management, and ethics and privacy. These topics were thoroughly explored during structured discussions, with a particular focus during the Early Career Researcher (ECR) session.
Dr. Paul Mbanka, Assistant Commissioner of Health Services, outlined the Ministry of Health’s commitment to addressing Zoonoses related cases citing presence of an incident management system, which includes an SMS-based mechanism for reporting diseases to the emergency response center. Upon detection of an alert, the information is verified, samples are collected, and if confirmed, a response is initiated. In terms of areas for improvement, Dr. Mbanka acknowledged the challenge of information sharing across various sectors. When asked about Data sharing by workshop participants, He also stated that the Ministry of Health is open to sharing data with researchers, provided it supports the Ministry’s goals
The two-day workshop concluded with an emphasis on the critical need for continued collaboration in the One Health sector. Participants, including Researchers, Academicians, PhD and Master’s students from Makerere University, and Uganda and Kenya registered students at Glasgow University made presentations and also engaged in strategic discussions on tackling zoonotic diseases, climate change, and the integration of digital innovations in health data management.
To conclude the workshop, Prof. Lawrence Mugisha, Professors Julien Reboud and Jon Cooper of the Makerere University and University of Glasgow respectively expressed their appreciation to all participants for the insightful presentations, discussions and emphasized the importance of ongoing partnerships across human, animal, and environmental health sectors.
Research
CARTA Graduate Dr. Drago on Advancing Research in Infectious Diseases
Published
4 weeks agoon
February 3, 2025
In our latest ‘Stories of Change’ feature, CARTA graduate, Kato Charles Drago, cohort 3, Makerere University shares his journey from an early-career scientist to a leading expert in infectious disease in Uganda. His work focuses on biomarkers for zoonotic diseases, securing over $5 million in research funding, and establishing a biosafety level 2 lab for high-impact research at Makerere. Beyond his research, Kato is mentoring the next generation of African scientists and strengthening regional collaborations.
Read the full story here
Source: CARTA Newsletter Issue 85
Veterinary & Biosecurity
The College of Veterinary Medicine, Animal Resources, and Biosecurity Marks Milestone Achievement
Published
1 month agoon
January 21, 2025
The College of Veterinary Medicine, Animal Resources, and Biosecurity presented a total of 186 students during the 75th Makerere University Graduation ceremony. This diverse cohort included 68 women and 118 men. Among the graduates, six earned their esteemed PhDs, showcasing the college’s commitment to advanced education and research.
In addition to celebrating the graduates, the event also honored faculty members for their exceptional contributions to research excellence. Senior career awards were presented to Prof. Mugisha Lawrence, Dr. Enoch Matovu, Prof. Kankya Clovice, Prof. Frank Norbert Mwiine, and Dr. Nyakarahuka Luke.
The Midcareer awards went to Dr. Muhanguzi Denis, Dr. Vudrico Patrick, Dr. Mutebi Francis, and Dr. Nanteza Ann. The Early career awards were given to Dr. Wilfred Eneku, Dr. Abigaba Rubaijaniza, and Dr. Paul Ssajakambwe. These awards highlight the college’s commitment to fostering excellence in research and education across various career stages.

During the first session of the Graduation ceremony held at the Freedom Square, the Chancellor Dr. Crispus Kiyonga in his remarks directed the integration of political economy teaching across all courses to enhance students’ understanding of the country’s socioeconomic conditions.

He said in the effort to further the research endeavors, the government pledged to increase Makerere University‘s research funding and strengthen partnerships with the private sector to commercialize innovations developed at the institution. Dr. Crispus Kiyonga, the newly appointed Chancellor, presided over the event and encouraged the university to establish an agro-industrial park on its land. “The parks would serve three purposes: teaching, generating income, and acting as a demonstration site for communities across the country,” he stated.
The ceremony was graced by Hon. Joyce Moriku Kaducu, Minister of State for Primary Education, who represented the First Lady and Minister of Education and Sports, Hon. Janet Kataaha Museveni. Other dignitaries included members of Parliament, the judiciary, the diplomatic corps, and academics. She lauded Makerere University for its dedication to academic excellence and innovation. “Today reflects the resilience, hard work, and commitment of our graduates, supported by the university staff, management, and parents,” she said. The Minister commended the Vice Chancellor and management for fostering research and innovation while urging them to maintain robust quality control systems to uphold the institution’s integrity. She also reflected on Makerere’s recent milestones, including the commissioning of a new School of Law building and the launch of the School of Graduate Studies and Research. “Your achievements stem from hard work, transparency, and accountability. They set Makerere apart as a leader in higher education,” she noted.
Vice Chancellor Highlights Makerere’s Impact

Vice Chancellor Prof. Barnabas Nawangwe congratulated the 13,658 graduates at Makerere University, including 143 PhD recipients and a notable 53% female graduates. He acknowledged the contributions of staff, parents, and sponsors in supporting the students’ educational journeys. Prof. Nawangwe highlighted the College of Veterinary Medicine’s significant contributions to biosecurity and sustainable food systems. He reiterated the university’s transformation into a research-led institution, driven by the government’s Research and Innovation Fund. Key national priorities being addressed include improving the Parish Development Model and advancing e-governance.
Highlights of CoVAB’s Notable Research Achievements
Prof. Nawangwe emphasized several significant research projects and accomplishments at the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB). He mentioned that in collaboration with the Uganda Virus Research Institute (UVRI) and supported by the Civilian Research and Development Foundation (CRDF) Global, CoVAB researchers are tackling the rising threat of cyberattacks on laboratories handling high-risk biological materials.
Furthermore, the Centre for Biosecurity and Global Health (CeBiGH) at CoVAB continues to advance the development of recombinant vaccines and diagnostics, with support from the Science Technology and Innovations Office of the President (STI-OP). They have established state-of-the-art laboratories with up to Biosafety Level 3 (BSL3) containment. These labs have developed prototype prognostic tests and vaccine prototypes for COVID-19, anti-tick vaccines, and East Coast Fever, expanding their research to other diseases requiring diagnostics and vaccines.
The Vice Chancellor also informed the gathering about the molecular and computational biology research group, led by Dr. Muhanguzi Dennis. This group, in partnership with the Foundation for Research and Technology-Hellas (FORTH) in Greece, leads a large consortium of seven sub-Saharan institutions to explore the role of ticks as disease vectors, focusing on Crimean-Congo Hemorrhagic Fever.
Additionally, the college, supported by the Swiss Government, is leading efforts to eliminate rabies in Uganda and the region through electronic surveillance. This initiative, using a one health approach, involves partnerships with the University of Zurich, the Ministry of Health, the Ministry of Agriculture, Animal Industry and Fisheries, and the Uganda Wildlife Authority, among others.
“Graduation Statistics of the 75th graduation ceremony

During the course of the 75th graduation ceremony, a total of 13,658 graduands received degrees and diplomas of Makerere University. 53 % of the graduands were female and 47% male. 44% of the PhD graduands were female. 16% of the graduates are graduating with post-graduate degrees and diplomas.

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