_{By Joseph Odoi}

On January 30-31, 2025, Makerere University in partnership with Glasgow, UK and University of Stockholm, Sweden with support from Europe’s CIVIS  University Alliance, organized a multi-disciplinary workshop at Kabira Country Club, Kampala, Uganda entitled “One Health and Diagnosing Zoonoses – Understanding the Importance of Climate Change in Disease Prevalence.” The event brought together a diverse group of stakeholders, including academicians, researchers, and practitioners, to collaborate on addressing public health challenges at the intersection of human, animal, and environmental health.

The workshop was organized and  officially opened by   Associate Professor Lawrence Mugisha   from the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB),  Makerere University alongside Professor Jonathan Cooper from the University of Glasgow, who led the CIVIS Alliance team to Uganda.  

In his opening address, Prof. Mugisha welcomed participants and  outlined the key objectives of the workshop. He noted that the primary aim of the workshop was to build new pathways for knowledge exchange and strengthen One Health capabilities within Uganda and East Africa in order to develop a better understanding of the role of climate change in disease dynamics (including zoonoses) in humans and animal health and their wellbeing.

Furthermore, the workshop sought to explore the regional links between zoonotic disease prevalence and climate change by using appropriate digital tools/systems that will, in future, have the potential to be used more widely in Sub-Saharan Africa.

On the impact of   Climate Change in Disease Prevalence, Professor Mugisha noted that the World Bank, the World Health Organization (WHO) and World Organisation for Animal Health (WOAH) have all warned around the need to better understand the harmful effects of climate change on health and disease, especially in low-and-middle-income-countries with such effects readily seen with Sub-Saharan Africa suffering some of the worst impacts.

‘’Uganda is also considered as a ‘hot spot’ for emerging and re-emerging infectious disease epidemics. The country has experienced several epidemics including; Ebola, Marburg, Plague, Rift Valley Fever, Yellow fever and Crimean Congo hemorrhagic fever. ‘’Many of these public health challenges arise from the interaction between humans-animals-environment and require a One Health approach as a collaborative effort of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals, plants and the environment.’’ added Professor Mugisha.

In his remarks, Professor Jonathan Cooper from the University of Glasgow acknowledged participants and provided a brief background on the CIVIC University Alliance. He stated that under CIVIS, multiple universities collaborate to offer joint learning pathways, research opportunities, and diverse degree programs, creating a dynamic network where students and academics can move freely between institutions. Through this collaboration, they work together to address societal challenges, including One Health and climate change, while also developing real-world solutions. He also commended the collaborative efforts of Makerere University, particularly those of Professor Lawrence Mugisha, in working across multiple disciplines at local, national, and global levels to achieve optimal health for people, animals, plants, and the environment.

Prof. Mugisha delivered a keynote address on climate change and human health and highlighted how climate change is causing unprecedented threats to human health, driving emergence of new infectious diseases and exacerbating the existing ones in addition to fueling frequent occurrence of severe natural catastrophes like floods, hurricanes and wildfires. He reported as per World Economic Forum Report of 2024, that climate change is projected by 2050 to cause additional 14.5 million deaths and $12.5 trillion in economic losses worldwide. He called upon all stakeholders to act together  through research, innovations and public directed interventions to reverse the potential impact of climate change. He provided examples of different research consortiums working together to contribute to finding solutions to address  the impacts of climate on health of humans, animals and entire ecosystem.  Highlighted Projects include DIDIDA-Improving disease diagnosis in Africa (Home – Didida), PREPARE4VBDS— A Cross-Disciplinary Alliance to Identify, PREdict and prePARE for Emerging Vector-Borne Diseases (prepare4vbd.eu) and recently funded DIDIDI- development of advanced, low-cost and deployable digital dashboards and diagnostics to understand how changes in climate are affecting the dynamics of soil-transmitted helminth (STH) and schistosomiasis in underserved rural community settings in sub-Saharan Africa

Dr. Frederick Monje, a focal person for the One Health Platform from the Ministry of Agriculture, Animal Industry and Fisheries (MAAIF), provided a brief background of the National One Health Platform of Uganda. He stated that the platform was established in 2016 to serve as a multi-sectoral coordination mechanism aimed at addressing public health threats arising from the interactions between humans, animals, and the environment.

Dr. Monje emphasized that the National One Health Platform in Uganda plays a critical role in surveillance, early detection, and rapid response to outbreaks through collaborations with district health teams, universities, and research institutions. He noted, “One Health is one of the ways to prevent the next pandemic. We need to do a lot of preparedness to prevent cross-cutting public health threats from coming to us. We have developed a number of training and partnerships with universities and many stakeholders to achieve the One Health objective.”

In his presentation, Mr. Monje also cited the World Bank’s report, highlighting that globally, zoonotic diseases sicken 2.4 billion people annually, kill 2.2 million, and affect more than 1 in 7 livestock. The direct economic costs of zoonotic diseases are estimated at 20  billion dollars per year. He pointed out that Uganda, due to its proximity to the Congo Basin and other hotspots, faces significant public health threats from zoonotic diseases.

Mr. Monje further emphasized that the platform’s impact is evident in its district-level One Health teams, which have strengthened Uganda’s pandemic preparedness and response to zoonotic diseases such as Ebola, Rift Valley Fever, and anthrax. He reiterated that One Health is critical to preventing future pandemics, requiring continuous preparedness, collaboration, and policy development to safeguard public health.

In her presentation, Ms. Patricia Nyinguro- Principal Meteorologist at the Kenya Meteorological Department revealed that there is rising temperatures in Kenya, showing an increasing trend since 1961, particularly in semi-arid regions. Despite this, she noted that public perception of heatwaves is low yet rising temperatures are key drivers of heat-related mortality, morbidity, and infectious diseases.

Moving forward,  Ms. Patricia emphasized the importance of interdisciplinary collaboration in developing heat health action plans and called for the development of indicators to measure progress in climate change adaptation.

In a digital technologies session, Dr. Xin Guo from the University of Glasgow shared insights on mobile health platforms for diagnostics, including demonstrations of relevant applications. He showed how apps can help diagnose diseases, especially zoonotic ones, and improve healthcare, especially in areas that need better disease tracking and response.

 Participants engaged in discussions on zoonoses, its impact, and the importance of the One Health approach. Key questions explored included: What are zoonoses? Why is One Health crucial? Who are the stakeholders involved, and how can zoonoses be effectively addressed?

Using the Double Diamond Methodology, participants in group discussions also identified the most pressing challenges that climate change poses or will pose on zoonoses, potential solutions, and the reasons why these solutions aren’t being implemented yet.

Key outcomes from the engagement included the drafting of a policy brief outline, which will guide future initiatives aimed at tackling public health threats.

The workshop also tackled important issues such as data interoperability, data ownership and management, and ethics and privacy. These topics were thoroughly explored during structured discussions, with a particular focus during the Early Career Researcher (ECR) session.

Dr. Paul Mbanka, Assistant Commissioner of Health Services, outlined the Ministry of Health’s commitment to addressing Zoonoses related cases citing presence of an incident management system, which includes an SMS-based mechanism for reporting diseases to the emergency response center. Upon detection of an alert, the information is verified, samples are collected, and if confirmed, a response is initiated. In terms of areas for improvement, Dr. Mbanka acknowledged the challenge of information sharing across various sectors. When asked about Data sharing by workshop participants, He also stated that the Ministry of Health is open to sharing data with researchers, provided it supports the Ministry’s goals

The two-day workshop concluded with an emphasis on the critical need for continued collaboration in the One Health sector. Participants, including Researchers, Academicians, PhD and Master’s students from Makerere University, and Uganda and Kenya registered students at Glasgow  University made presentations and also engaged in strategic discussions on tackling zoonotic diseases, climate change, and the integration of digital innovations in health data management.

To conclude the workshop, Prof. Lawrence Mugisha, Professors Julien Reboud and Jon Cooper of the Makerere University and University of Glasgow  respectively expressed their appreciation to all participants for the insightful  presentations, discussions and emphasized the importance of ongoing partnerships across human, animal, and environmental health sectors.

In our latest ‘Stories of Change’ feature, CARTA graduate, Kato Charles Drago, cohort 3, Makerere University shares his journey from an early-career scientist to a leading expert in infectious disease in Uganda. His work focuses on biomarkers for zoonotic diseases, securing over $5 million in research funding, and establishing a biosafety level 2 lab for high-impact research at Makerere. Beyond his research, Kato is mentoring the next generation of African scientists and strengthening regional collaborations.

Read the full story here

Source: CARTA Newsletter Issue 85

The College of Veterinary Medicine, Animal Resources, and Biosecurity presented a total of 186 students during the 75^th Makerere University Graduation ceremony. This diverse cohort included 68 women and 118 men. Among the graduates, six earned their esteemed PhDs, showcasing the college’s commitment to advanced education and research.

In addition to celebrating the graduates, the event also honored faculty members for their exceptional contributions to research excellence. Senior career awards were presented to Prof. Mugisha Lawrence, Dr. Enoch Matovu, Prof. Kankya Clovice, Prof. Frank Norbert Mwiine, and Dr. Nyakarahuka Luke.

The Midcareer awards went to Dr. Muhanguzi Denis, Dr. Vudrico Patrick, Dr. Mutebi Francis, and Dr. Nanteza Ann.  The Early career awards were given to Dr. Wilfred Eneku, Dr. Abigaba Rubaijaniza, and Dr. Paul Ssajakambwe.  These awards highlight the college’s commitment to fostering excellence in research and education across various career stages.

During the first session of the Graduation ceremony held at the Freedom Square, the Chancellor Dr. Crispus Kiyonga in his remarks directed the integration of political economy teaching across all courses to enhance students’ understanding of the country’s socioeconomic conditions.

He said in the effort to further the research endeavors, the government pledged to increase Makerere University‘s research funding and strengthen partnerships with the private sector to commercialize innovations developed at the institution. Dr. Crispus Kiyonga, the newly appointed Chancellor, presided over the event and encouraged the university to establish an agro-industrial park on its land. “The parks would serve three purposes: teaching, generating income, and acting as a demonstration site for communities across the country,” he stated.

The ceremony was graced by Hon. Joyce Moriku Kaducu, Minister of State for Primary Education, who represented the First Lady and Minister of Education and Sports, Hon. Janet Kataaha Museveni. Other dignitaries included members of Parliament, the judiciary, the diplomatic corps, and academics. She lauded Makerere University for its dedication to academic excellence and innovation. “Today reflects the resilience, hard work, and commitment of our graduates, supported by the university staff, management, and parents,” she said. The Minister commended the Vice Chancellor and management for fostering research and innovation while urging them to maintain robust quality control systems to uphold the institution’s integrity. She also reflected on Makerere’s recent milestones, including the commissioning of a new School of Law building and the launch of the School of Graduate Studies and Research. “Your achievements stem from hard work, transparency, and accountability. They set Makerere apart as a leader in higher education,” she noted.

Vice Chancellor Highlights Makerere’s Impact

Vice Chancellor Prof. Barnabas Nawangwe congratulated the 13,658 graduates at Makerere University, including 143 PhD recipients and a notable 53% female graduates. He acknowledged the contributions of staff, parents, and sponsors in supporting the students’ educational journeys. Prof. Nawangwe highlighted the College of Veterinary Medicine’s significant contributions to biosecurity and sustainable food systems. He reiterated the university’s transformation into a research-led institution, driven by the government’s Research and Innovation Fund. Key national priorities being addressed include improving the Parish Development Model and advancing e-governance.

Highlights of CoVAB’s Notable Research Achievements

Prof. Nawangwe emphasized several significant research projects and accomplishments at the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB). He mentioned that in collaboration with the Uganda Virus Research Institute (UVRI) and supported by the Civilian Research and Development Foundation (CRDF) Global, CoVAB researchers are tackling the rising threat of cyberattacks on laboratories handling high-risk biological materials.

Furthermore, the Centre for Biosecurity and Global Health (CeBiGH) at CoVAB continues to advance the development of recombinant vaccines and diagnostics, with support from the Science Technology and Innovations Office of the President (STI-OP). They have established state-of-the-art laboratories with up to Biosafety Level 3 (BSL3) containment. These labs have developed prototype prognostic tests and vaccine prototypes for COVID-19, anti-tick vaccines, and East Coast Fever, expanding their research to other diseases requiring diagnostics and vaccines.

The Vice Chancellor also informed the gathering about the molecular and computational biology research group, led by Dr. Muhanguzi Dennis. This group, in partnership with the Foundation for Research and Technology-Hellas (FORTH) in Greece, leads a large consortium of seven sub-Saharan institutions to explore the role of ticks as disease vectors, focusing on Crimean-Congo Hemorrhagic Fever.

Additionally, the college, supported by the Swiss Government, is leading efforts to eliminate rabies in Uganda and the region through electronic surveillance. This initiative, using a one health approach, involves partnerships with the University of Zurich, the Ministry of Health, the Ministry of Agriculture, Animal Industry and Fisheries, and the Uganda Wildlife Authority, among others.

 “Graduation Statistics of the 75th graduation ceremony

During the course of the 75^th graduation ceremony, a total of 13,658 graduands received degrees and diplomas of Makerere University. 53 % of the graduands were female and 47% male. 44% of the PhD graduands were female. 16% of the graduates are graduating with post-graduate degrees and diplomas.