The project team, Dr. Robinson Odong (C), Dr. Peter Akoll (R) and Mr. John Omara (L) share notes shortly before the stakeholders meeting in Mbarara City on 31st May 2022.
Most of the antibiotics used to manage diseases in humans and livestock end up in the environment. Antibiotics (ATBs), Antibiotic Resistant Bacteria (ARB), and Antibiotic Resistance (ARGs) have spread in almost all habitats globally. The Food and Agricultural Organization (FAO), World Health Organization (WHO), and the World Organization for Animal Health (OIE) recognize the problem of Antimicrobial Resistance (AMR), and thus recommend: Prudent use of antimicrobials; and a “One Health Approach” to mitigate the problem. Antimicrobial Resistance (AMR) is a situation where bacteria develop resistance against antibiotics intended to destroy them.
Dr Robinson Odong briefing stakeholders about the project
Antibiotics in the environment may induce AMR in bacteria, hence the risk of transfer to humans and wildlife. AMR reduces effectiveness of antibiotics, leading to higher costs of treatment, severe illnesses, and deaths. Globally, about 1.2 million people died in 2019 due to complications of AMR; Sub-Saharan African region alone had 255,000 deaths (Murray et al., 2022, The Lancet, https://doi.org/10.1016/S0140-6736(21)02724-0).
Assoc. Prof. Charles Masembe, Department of Zoology, Entomology and Fisheries Sciences, CoNAS, Makerere University. He conducts research on animal diseases using molecular epidemiology tools with special focus on African Swine Fever genetics.
The Strategic Research Agenda by the Joint Programming Initiatives (JPI) calls for transnational studies on AMR in both terrestrial and aquatic environments. Indeed, the role of livestock, wildlife and migratory birds in the spread of AMR has previously been under-emphasized, yet they are major reservoirs of ARB and ARG.
Dr Peter Akoll engages stakeholders on the commonly used antibiotics and the potential sites for sample collection
The PAIRWISE Project is being implemented in three countries in Europe, and two in Africa. PAIRWISE is investigating the risks posed to human health and the environment by pollutants and pathogens present in water resources. The project also aims to investigate the dispersal of ATB, ARB and ARG downstream Wastewater Treatment Plants (WWTPs) by comparing different geographical/climatic regions, wastewater management practices and types of water bodies.
Project partners include; National Veterinary Institute (SVA), Sweden; Norwegian Institute for Water Research (NIVA), Norway; Linköping University (LiU), Sweden; Doñana Biological Station, Higher Council for Scientific Research, Spain; National Research Institute for Rural Engineering, Water, and Forestry, Tunisia; Faculty of Medicine Ibn Al-Jazzar Sousse, Tunisia; and the College of Natural Sciences, Makerere University, Uganda.
Mr. David Nuwagaba, Mbarara District Natural Resources Officer sharing his views at the stakeholders meeting
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 869178-AquaticPollutants, Joint Programming Initiative on Anti-microbial Resistance (JPIAMR), www.waterjpi.eu; and JPI Oceans, www.jpi-oceans.eu. For Uganda, the three-year project is funded by the Swedish International Development Agency (Sida). The African Population and Health Research Center, Nairobi, www.aphrc.org coordinates the funding in Uganda.
One of the study areas, River Rwizi Catchment
In Uganda, the research activities are being conducted by researchers from the College of Natural Sciences, Makerere University including: Prof. Charles Masembe (Principal Investigator), Dr. Robinson Odong, Dr. Peter Akoll, Mr. Mayega Johnson (Department of Zoology, Entomology and Fisheries Sciences) and Mr. John Omara (Department of Biochemistry and Sports Sciences) as team members. The study area in Uganda includes the catchment of River Rwizi, Lake Mburo National Park, and River Aswa.
The Team visits one of the study areas, River Rwizi Catchment
The research will contribute towards better understanding of the factors which influence the occurrence and spread of AMR in water systems, livestock farms, and birds. It will also contribute towards the Government of Uganda’s framework to combat the threat of AMR, through the National AMR Action Plan; design policies to reduce the risks of AMR, and the costs incurred for animal and human disease management.
Dr Peter Akoll moderated the discussion on potential sites for sample collection
On 31st May 2022, the project team from the Department of Zoology, Entomology and Fisheries Sciences led by Prof. Charles Masembe (Principal Investigator) held a consultative meeting to get buy-in and introduce the PAIRWISE Project to the key stakeholders in Greater Mbarara and River Rwizi catchment. The meeting also aimed to receive input from key stakeholders regarding the use of antibiotics in Greater Mbarara district and River Rwizi catchment, to document challenges of Antimicrobial Resistance and identify potential sites for fieldwork.
Mr John Omara from the Department of Biochemistry and Sports Sciences sharing his views on the study
The meeting was attended by administrators, senior health, water and environmental officers in Mbarara City and District including:
The District Chief Administration Officer represented by Mr Bakashaba Innocent
Mr David Nuwagaba, the District Natural Resources Officer
Mr Tumwebaze Herbert, Environment Officer, Mbarara City
Dr Oriokot Francis, Deputy Director, Mbarara Regional Referral Hospital
Dr Akashaba Andrew, Mbarara District Veterinary Officer
Mr Mwesigye Joseph, Environment Officer, Mbarara District
Mr Katongole Joseph, a farmer in Mbarara District
Mr Ayebare Calist, Fisheries Officer, Isingiro District, and a fresh graduate (May 2022, Makerere University 72nd Graduation) assisted in organizing the Stakeholders meeting. During the meeting, Dr Robinson Odong on behalf of Prof. Charles Masembe shared the project overview with participants, outlining the challenges of AMR, and expectations from the research. Stakeholders brainstormed and listed the commonly used antibiotics and the potential sites for sample collection. The research will take the One Health Approach, encompassing aspects of human, animal and environmental health.
Some of the District officials who participated in the PAIRWISE project consultative meeting in Mbarara City
Capacity Building under PAIRWISE Project
As part of the PAIRWISE capacity building component, the project is supporting research activities of two graduate students: Ms. Ndinawe Ruth Pamela (Master of Science in Molecular Biology) studying “The dispersal of antimicrobial resistance bacteria and genes through aquatic birds under different climatic and geographical conditions”; and Mr. George Katende (Master of Science in Immunology and Clinical Microbiology), studying “Characterization of clinically important antibiotic resistant bacteria and genes in river waters upstream and downstream of WWTPs and hospital effluent” https://cns.mak.ac.ug/blog/call-applications-msc-scholarship-under-pairwise-project.
Mr Ayebare Calist (R), Fisheries Officer, Isingiro District and Mr Katongole Joseph, a farmer in Mbarara District at the stakeholders meetingThe Team on the banks of River Rwizi, Isingiro District.Cattle watering in River Rwizi, Isingiro District. The water is also used for human consumption. PAIRWISE is investigating the risks posed to human health and the environment by pollutants and pathogens present in water resourcesA student drawing water from River RwiziThe Project team with farmers in Isingiro District
Dr. Jackson Efitre, a Senior Lecturer at the Department of Zoology, Entomology, and Fisheries Sciences, College of Natural Sciences (CoNAS), Makerere University has been appointed as a Lead Author for the Intergovernmental Panel on Climate Change (IPCC) Seventh Assessment Report. He was amongst the 664 experts nominated by governments and selected by the IPCC Bureau from a global pool of 3,771 nominees. This prestigious appointment recognizes his extensive expertise and significant contributions to climate science globally. Dr. Efitre previously contributed to the Africa chapter of IPCC’s 6th Assessment Report that was launched in 2022. In the seventh assessment cycle, Dr. Efitre will contribute to Working Group II: Impacts, Adaptation and Vulnerability, Chapter 17: Agriculture, Food, Forestry, Fiber and Fisheries.
IPCC Assessment Reports are the most authoritative assessment of the state of knowledge on climate science, mitigation and adaptation. Commissioned by nearly all governments, the reports are key in informing climate policy, and shaping international climate negotiations.
We congratulate Dr. Efitre on joining a distinguished group of experts who will contribute to this crucial undertaking for global climate policy.
Newly admitted students to the College of Natural Sciences (CoNAS) have been strongly encouraged to make academic excellence their top priority as they begin their university journey. During the official College orientation held on 6th August 2025, continuing students shared valuable insights aimed at helping the freshers adapt and thrive both academically and socially in the university environment.
Speaking at the event, Ms. Britah Kemigisha and Mr. Leakey Mbabazi, students of Conservation Biology and Petroleum Geosciences respectively, offered practical advice drawn from their experiences at CoNAS. The two students emphasized the importance of time management, consistent class attendance, and fostering healthy academic competition.
“Be ambitious and attend classes because attendance earns you some marks. Be competitive in a way that promotes excellence,” Mbabazi advised. He encouraged freshers to approach university life with purpose, noting that unlike in high school, university students must take personal responsibility for their learning outcomes. He recommended the use of professional networking platforms like LinkedIn, emphasizing their value in facilitating meaningful connections, expanding one’s professional network, discovering job opportunities, and staying updated on industry trends and insights.
Dr Joel Isanga briefing students about the Department of Biochemistry and Systems Biology.
Ms. Kemigisha underscored the importance of building supportive peer networks. “Form groups and inspire each other with rewards based on academic excellence,” she advised, emphasizing that academic group work, peer mentorship, and study circles can be powerful tools for motivation and accountability. According to her, surrounding oneself with goal-oriented individuals creates a positive learning environment that fosters growth and resilience, especially when faced with academic challenges.
The Dean, School of Physical Sciences, Prof. Michael Owor addressing the freshers about the different departments and programmes in the schoolSome of the freshers and college administrators at the orientation held on 6th August 2025 at JICA.
The orientation programme served as a platform to introduce First Year students to the academic programmes, services, and student life at CoNAS and the University in general. The session led by the Deputy Principal, Prof. Juma Kasozi featured presentations by both College and University leaders, who sensitized the new students on key university policies, academic structures, and support services. School Deans and Heads of Departments in attendance briefed students on the specific programmes offered within their respective units. These included the Dean, School of Physical Sciences, Prof. Michael Owor; the Dean, School of Biosciences, Prof. Arthur Tugume; the Head, Department of Biochemistry and Systems Biology, represented by Dr Joel Isanga; the Head, Department of Chemistry, Dr Emmanuel Tebandeke; the Head, Department of Geology and Petroleum Studies, Dr Arthur Batte; the Head, Department of Mathematics, Dr Ismail Mirumbe; the Head, Department of Physics, Dr Denis Okello; the Head, Department of Zoology, Entomology, and Fisheries Sciences, Dr Godfrey Kawooya Kubiriza; the Head, Department of Plant Sciences, Microbiology, and Biotechnology represented by Dr Godwin Anywar, and a representative from the Department of Exercise and Sports Science. Students were also sensitized on the registration and examination processes, ICT support services, library services, fees payment policies, the Anti-sexual Harassment Policy, counselling and guidance services, the emerging leaders programme, and general welfare at the University.
The Dean, School of Biosciences, Prof. Arthur Tugume addressing the students.
On behalf of the Principal, the Deputy Principal, Prof. Juma Kasozi warmly welcomed the newly admitted students to the College.He provided an insightful overview of the key academic units and programmes offered both within the College and across the University. In his address, Prof. Kasozi congratulated the students on securing admission into one of the most competitive, vibrant, and intellectually rigorous colleges within the University. He encouraged the students to take full ownership of their academic journey, emphasizing the importance of commitment, discipline, and focus from the very beginning. Highlighting the value of hard work and determination, he reminded them that the foundation they lay now will shape their future success.
Dr Emmanuel Tebandeke addressing the students about the programmes in the Department of Chemistry.
In his address, the Manager of the Counselling and Guidance Centre at the University, Mr. Henry Nsubuga, emphasized the importance of safeguarding mental health. He urged students to prioritize their psychological well-being, noting that maintaining a healthy mind is fundamental for academic success and overall personal development. Mr. Nsubuga encouraged students to actively seek support and adopt positive coping mechanisms to navigate the pressures of academic life.
Mr. David Kisitu, ICT Officer at CoNAS moderated the session.Dr Godfrey Kawooya Kubiriza briefed students about the programmes in the Department of Zoology, Entomology, and Fisheries Sciences, and the significance of the natural sciences in general.Dr. Arthur Batte (L) addressing students about the Department of Geology and Petroleum Studies.Dr. Godwin Anywar represented the Head, Department of Plant Sciences, Microbiology, and Biotechnology.Ms. Britah Kemigisha, a prospective BSc. Conservation Biology graduand briefing students on how to plan for a good CGPA.Mr. Leakey Mbabazi, a prospective Bachelor of Petroleum Geosciences graduand, also offered valuable tips on achieving academic excellence.Mr James Muhwezi, on behalf of student leaders at CoNAS briefed students about life on Campus.Dr Barbara Nerima from the Department of Biochemistry and Systems Biology briefed students on the emerging leaders programme at the University.Some of the students listening to officials.A section of officials at the orientation.
The lectures are expected to commence on Monday, 11th August 2024.
Researchers from the Department of Plant Sciences, Microbiology, and Biotechnology at the College of Natural Sciences (CoNAS), Makerere University have highlighted the urgent need to conserve medicinal plants in the face of increasing threats from climate change, over-harvesting, and habitat destruction.
Despite Namutumba District’s rich diversity of medicinal plants, conservation efforts are limited, and several species are already classified as globally and nationally threatened. This highlights the urgent need for focused conservation strategies to safeguard these vulnerable medicinal plants.
Dr Tugume addressing the workshop participants on the key research findings.
Under a project titled “Knowledge, Attitudes, and Conservation of Commonly Traded Medicinal Plants in a Climate-Changing Environment in Eastern Uganda,” a team of researchers led by Dr Patience Tugume documented 174 medicinal plant species. The goal was to assess the existential threats facing these plants due to unsustainable harvesting practices and the lack of effective conservation measures. These species are widely used to treat various health conditions, including malaria, syphilis, diabetes, hypertension, and certain cancers. The findings of the study are intended to guide the development of species-specific, evidence-based interventions to curb possible extinction and loss of medicinal plant resources. The research revealed troubling trends in the availability of key medicinal plants, including:
The herbalists mostly collected their medicinal plants from bushlands (92.0%), markets (82.3%) and wetlands (74.7%) and were rarely cultivated. This is of great concern regarding the conservation and future availability of these resources.
It was noted that 36% of the herbal products were made from roots, which presents a conservation threat since the heavy utilization of roots affects the regeneration of the medicinal plants.
Common plants used were: Kigelia africana (Naibere), Erythrina abyssinica (Ekiyirikiti) and Geranium sauveolens (Lokowe). Kigelia africana was the most cited species by the herbalists, indicating heavy utilization and a high conservation threat if deliberate measures are not taken to ensure its future availability.
Almost all respondents (289, 96.3%) acknowledged a considerable decline in the availability of 13 medicinal plants species including Aloe wollastonii (Ekigagi), Commiphora africana (Nkulidho), Myrica kandtiana (Mukikimbo) and Acacia sieberiana (Mufundawuzi).
Four plant species i.e. Tamarindus indica (Enkoge), Warburgia ugandensis (Balwegira), Mitragyna rubrastipulata (Mutamatama) and Mondia whitei (Mulondo) appear on the Red List of Globally and Nationally Threatened Species and were mentioned among the plants whose population has greatly declined.
The causes of decline in availability of medicinal plants included climate change, overharvesting, agricultural expansion, habitat destruction, land use change and inadequate regulations.
There were no medicinal plant conservation efforts by herbalists.
Kigelia africana was the most cited species by the herbalists, indicating heavy utilization and a high conservation threat.Participants included leaders of the herbalist associations, traders and research assistants.
The study recommended the following practices to ensure conservation of the medicinal plants:
Promote the use of sustainable harvesting techniques to ensure conservation of medicinal plants.
Conduct capacity building for stakeholders in the medicinal plants sector on conservation, value addition and standardization.
Establish community botanical gardens raw plant collection and sensitization programmes.
Advocate for agroforestry among herbalists to reduce the dependence on natural habitats.
Develop and enforce regulations on accessing natural areas for medicinal plants.
Promote conservation awareness campaigns.
Dr Tugume appreciating the Chief Administrative Officer-Namutumba, Mr. Ofwono Emmanuel for hosting the Dissemination Workshop at the District Offices.
Research Dissemination in Namutumba District
At the research dissemination workshop held in Namutumba District on 23rd July 2025, and attended by district leaders, researchers, and local herbalists, the project team led by Dr Patience Tugume expressed hope that the insights gained from the project, particularly in medicinal plants conservation approaches, will be invaluable for minimising the decline in medicinal plants.
The Resident District Commissioner-Namutumba, Mr. Fred Aggrey Bangu (Standing), the PI, Dr Patience Tugume (Right), and the LC5 Chairperson, Mr. Mutyaba Patrick (Left).
In her remarks, Dr Tugume, thanked the Government of Uganda through the Makerere UniversityResearch and Innovations Fund (MakRIF) for funding the project. She expressed gratitude to the research team composed of Dr Abubakar Sadik Mustafa, Dr Jamilu E. Ssenku, Dr Savina Asiimwe, and Dr Abdul Walusansa who have worked with her closely from project inception in February 2024. She further thanked the research assistants and all respondents, mainly the herbalists that participated in the study.
In a special way, she appreciated Mr. Fred Aggrey Bangu (Resident District Commissioner), Mr. Ofwono Emmanuel (Chief Administrative Officer), Mr. Kiire Noah (Communication Officer), Mr. Mugunywa Enock (District Community Development Officer), Mr. Kirya Moses (District Environmental Officer), Mr. Bamusubire William (District Forest Officer) and the leaders of herbalist associations for providing support throughout the study and sparing time to attend the dissemination workshop.
The MakRIF research Team. Left to right: Mr. Ronald Muwanika, Dr Savina Asiimwe, Dr Patience Tugume (Principal Investigator), Dr Abubakar Sadik Mustafa, and Dr Abdul Walusansa.
Addressing the participants, the Resident District Commissioner, Mr. Fred Aggrey Bangu urged all stakeholders to engage in a collaborative discussion on how the study findings can be translated into practical solutions to promote sustainable use and conservation of commonly used medicinal plants in Namutumba District amidst adverse effects of climate change.
The MakRIF project team with leaders of the Traditional Herbalist Associations.
Mr. Ofwono Emmanuel, the Chief Administrative Officer, praised the Makerere research team for selecting Namutumba as the study area. He said the research served as an eye-opener to the district officials and community, especially regarding the pressure exerted on natural medicinal resources.
Front left to right: Mr. Ronald Muwanika (Coordinator), Mugega Amos (Sec. Health), Mutyaba Patrick (LC 5), Bangu Fred (Resident District Commissioner), Dr Patience Tugume (Principal Investigator), Ms. Kiire Noah (Communication Officer), Dr Abubakar Sadik Mustafa (Researcher). Back left to right: Mugunywa Enock (District Community Development Officer), Kirya Moses (District Environmental Officer), Bamusubire William (District Forest Officer). Dr Savina Asiimwe (Researcher), and Dr Abdul Walusansa (Researcher).
Report compiled by Dr Patience Tugume and Dr Abubakar Sadik Mustafa – Department of Plant Sciences, Microbiology and Biotechnology, CoNAS, Makerere University