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Mak Launches Homegrown COVID-19 Rapid Antibody Test Kits

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By: Harriet Adong, Mak-RIF Communications Officer

The afternoon of Wednesday March 17th, 2021 saw Makerere University’s Department of Immunology and Molecular Biology, College of Health Sciences (CHS) launch the homegrown COVID-19 Rapid Antibody Test Kits. The COVID-19 Rapid Antibody Test Kits developed domestically aim to address challenges related to affordability/cost using imported items, promote research and innovation in the medical/health field and Makerere University in general.

This project was spearheaded by Dr. Misaki Wayengera, Director Biomedical Research at the Department of Immunology and Molecular Biology, College of Health Sciences, Makerere University. Dr. Wayengera is also the Chairperson of the Scientific Advisory Committee on the COVID-19 Taskforce in the Ministry of Health. These efforts are directed towards enhancing the fight against the spread of the Corona Virus not only at Makerere University but also in the entire country. Explaining the advantages of the project, Dr. Wayengera said “Makerere University has developed an affordable (costing less than US $1), easy to use (requiring minimal expertise, user guide), rapid (yielding results within 2-5 minutes) point of care test platform for COVID-19 suited for use within remote equatorial African settings. This will enable rapid testing for Coronavirus and considerably lower the cost of testing currently standing at USD 65, which is prohibitive for developing countries like Uganda. This could not have been achieved without the financial support of Partners and Institutions such as Supervised Financial Institutions under their umbrella body Uganda Bankers Association, Deposit Protection Fund of Uganda, and Government of the Republic of Uganda, the French Embassy in Uganda and Uganda’s Ministry of Science Technology and Innovation’’.

The Test Kit involves using a swab-tube dipstick to do an antigen test by use of a nasal sample. With this quick test, once the nasopharyngeal sample is obtained, it is placed back into its tube containing reagents that detect the virus surface protein.

French Ambassador to Uganda-H.E. Jules-Armand Aniambossou (2nd L) cuts the tape to unveil the Test Kits as Hon. Dr. Jane Ruth Aceng (2nd R), Hon. Dr. Elioda Tumwesigye (2nd L) and Dr. Misaki Wayengera (R) witness.

This event was attended by Uganda’s Minister of Health; Hon. Dr. Jane Ruth Aceng Ocero, Uganda’s Minister of Science Technology and Innovation; Hon. Dr. Elioda Tumwesigye, French Ambassador to Uganda; His Excellency Jules-Armand Aniambossou, the World Health Organization Country Representative; Dr. Yonas W. Tegeny, Uganda’s Director General at Ministry of Health; Dr. Henry Mwebesa and the Permanent Secretary at Ministry of Health; Dr. Diana Atwine. The funders were also represented at the event and these included; Makerere University Research and Innovations Fund (Mak-RIF) represented by Dr. Roy William Mayega, Mak-RIF Coordinator, Uganda Bankers Association represented by Mr. Wilbrod Owor, the French Embassy and Ministry of Science Technology and Innovation like earlier listed  among other dignitaries.

At the occasion, Prof. Damalie Nakanjako, Principal Makerere University College of Health Sciences represented Makerere University’s Vice Chancellor Prof. Barnabas Nawangwe. She welcomed all scientists, innovators and the media fraternity (representing the community) to witness yet another stride in and by faculty in Uganda’s leading higher institution of learning-Makerere University. In her remarks, she noted that, the University has through College of Health Sciences built extensive expertise, experience and eco-systems across the academia and partnerships for Research and Development of pathogen diagnostic. “This kit will carry out antibody tests. It will also be used in early detection of COVID-19 cases, used in screening of travelers for COVID-19, detection of symptoms as well as aid in sero-prevalennce studies to determine previous exposure to COVID-19. Makerere University is hopeful that this will enable Uganda and other African countries to cost-effectively respond to the COVID-19 pandemic”.

Makerere University is grateful for the SEED funding (UGX 65, 527, 020) from the Government of the Republic of Uganda through Makerere University Research and Innovations Fund (Mak-RIF) which aided initialization of this project. The Government of the Republic of Uganda is funding cross disciplinary research and innovations (over 500 projects now, up to a tune of Uganda Shillings 60 billion only for the last two financial years). Makerere University faculty and students have through this initiative engaged with other institutions, organizations, disciplines and Ministries enhancing research and innovations in and outside the institution. For all this support, we are truly grateful to the Government of the Republic of Uganda and all our other funders/partners, Prof. Nakanjako added.

Minister of Science Technology and Innovation-Hon. Dr. Elioda Tumwesigye (R) chats with the Host and Principal College of Health Sciences (CHS)-Prof. Damalie Nakanjako (L) at the event. Centre is MoSTI’s Dr. Maxwell Onapa Otim

Hon. Dr. Elioda Tuwesigye, Minister of Science Technology and Innovation in Uganda noted that such strides like the launch of Makerere University homegrown COVID-19 Rapid Antibody Test Kits was only a wake-up call to all of us that the virus is still with us and we can together do so much to up the fight against further spread and effects. He thanked the Government of the Republic of Uganda for funding research and innovations in Makerere University and other institutions too. “It is through research that we garner additional knowledge to enable us to be and remain creative. Embracing Research and Innovation is the way to go if we are to realize development in our country, Africa and the globe’’, he added.

Uganda’s Minister of Health at the event in her remarks congratulated all scientists at Makerere University including Dr. Wayengera and his research for working closely with the Ministry to respond to diverse community challenges and in this case the Coronavirus. She noted that this virus is still with us and thus the need for us to continue observing the Standard Operating Procedures, researching ad innovating to carry on with the fight.  She added that some countries were experiencing the second and third wave of Coronavirus and thus Ugandans must remain on the alert regardless of the circumstances at the moment so that these waves do not crop in and sweep away the population. Hon. Dr. Aceng said: “These rapid antibody testing kits come at a point when we are preparing for the next wave of the COVID-19 pandemic, thank you Dr. Wayengera and team.’’ 

His Excellency Jules-Armand Aniambossou, French Ambassador in his remarks noted that the French Embassy in Uganda was and is happy to collaborate with and further support Makerere University’s efforts to respond to the Coronavirus. He said “Uganda’s response to COVID-19 was and is strong, immediate ad efficient. We need to learn from Uganda. Uganda can compete globally. Well done Scientists, he said as he officially launched the homegrown COVID-19 Rapid antibody Test Kits’’.

L-R: Mak-RIF Representative-Dr. Roy William Mayega, Uganda Bankers’ Association (UBA) Executive Secretary-Mr. Wilbrod Owor and MoSTI’s Dr. Maxwell Onapa Otim showcase the unveiled kits

In the drive to raise funds towards the fight against the COVID-19 pandemic, and in response to Government’s call for support to join hands, Members of Uganda Bankers Association (UBA) and the Deposit Protection Fund contributed UGX. 200million to the project which was in advanced stages in 2020. Speaking at the occasion, Mr. Wilbrod Owor-Executive Director UBA applauded Makerere University for the research efforts as an academic institution and the quick turnaround invention. “The pandemic has had diverse effects on the economy and one of the most affected sectors are education, tourism & hospitality, real estate which ultimately have affected the banking sector by way of increase in Non-Performing Loans.  In addition to the loan restructures that member banks have offered, as part of support to business community, we are also happy to have invested to support testing. Therefore, the affordability of this intervention is much welcome to address cost issues that would otherwise have to be so high for an average Ugandan” Owor said.

Dr. Roy William Mayega, Coordinator at the Makerere University Research and Innovations Fund (Mak-RIF) on behalf of Prof. William Bazeyo, Chair Mak-RIF thanked Dr. Wayengera and his research/innovation team for the work well done. He also thanked all funders for positively responding to the call for more resources to realize this project. He said “It is only when funders see such research and innovation outputs like the COVID-19 Rapid antibody Test Kits we are holding in our hands now that they will look further into their Bank Accounts to raise more resources to further support research and innovations. Thank you Dr. Wayengera and all the other Scientists for leading by doing. Let us continue with these efforts’’.

Dr. Wayengera acknowledged all the support/funding and gave each donor a pack of the COVID-19 Rapid Antibody Testing Kits.

Minister of Health-Hon. Dr. Jane Ruth Aceng (L) and Director General of Health Services-Dr. Henry Mwebesa (2nd L) lead the volunteers who experienced antibody testing after the Test Kits’ launch.

The event host, Prof. Nakanjako, Principal at Makerere University’s College of Health Sciences then thanked all participants and welcomed them to further engage in a cocktail as volunteers led by the Director General and Minister of Health experienced antibody testing using the newly launched kits. The rest of the COVID-19 Test Kits will be used in the Makerere University Medical School laboratories

Congratulations Makerere University and congratulations the Government of the Republic of Uganda!

‘We Build for the Future, For God and My Country’

View and read about this launch in the Media

  1. New COVID-19 rapid antibody test kits launched to reduce cost and promote research. – https://joripress.com/new-covid-19-rapid-antibody-test-kits-launched-to-reduce-cost-and-promote-research
  2. https://www.ntv.co.ug/ug/news/national/local-testing-ability-improves-with-new-covid-19-kits-3326454
  3. https://chimpreports.com/makerere-launches-own-covid19-testing-kit/
  4. https://www.independent.co.ug/makerere-university-launches-covid-19-anti-body-test-kits/
  5. https://twitter.com/JaneRuth_Aceng/status/1372187357781360642?s=1002
  6. https://www.monitor.co.ug/uganda/news/national/scientists-behind-uganda-s-first-coronavirus-test-kits-3327390
  7. New Vision Newspaper Friday March 19th , 2021, Page 10
  8. Daily Monitor Newspaper Thursday March 18th , 2021 Page 6

Mark Wamai

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Makerere Public Health Showcases EU Funded Research

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Makerere University’s School of Public Health (MakSPH) showcased research, training and international partnerships supported through European Union funding during the EU Uganda Research and Study Fair 2026 held at Makerere University.

The fair brought together students, researchers, academics, government representatives and development partners to explore opportunities in education, research, innovation and international collaboration, while celebrating 50 years of partnership between Uganda and the European Union.

Through its exhibition, MakSPH highlighted research and capacity building initiatives addressing public health challenges including infectious diseases, non communicable diseases, health systems, climate change and pandemic preparedness.

18 EU funded projects supported at MakSPH

Prof. Rhoda Wanyenze, Dean of Students, School of Public Health, said the School has benefited from 18 EU funded projects over the past five years, supporting research and training across several areas of public health.

Prof. Rhoda Wanyenze explains MakSPH research projects to Acting Minister of Education and Sports Dr John Chrysostom Muyingo during a tour of exhibition stands at the EU Uganda Research and Study Fair.

She said the projects have contributed to the training of PhD researchers and the development of research addressing infectious diseases and prevention, non communicable diseases, health systems, climate change and health.

Prof. Wanyenze also highlighted a new five year programme which started in 2021 that is aiming at strengthening capacity for research on pandemic preparedness and response, including outbreaks such as Ebola.

Stella Kakeeto interacts with students during the EU Uganda Research and Study Fair

Another programme being undertaken with the Ministry of Health and Karolinska Institute focuses on improving maternal health while also addressing adolescent pregnancy and the health of mothers and children.

She described partnerships as critical to advancing science and innovation, noting that collaboration allows researchers in Africa and Europe to share knowledge and strengthen the impact of research on communities.

Research partnerships strengthen innovation

Prof. Robert Wamala, Director of the Directorate of Research, Innovation and Partnerships at Makerere University, said the exhibition provided an opportunity to showcase EU funded projects across the University.

He noted that the School of Public Health alone has more than 18 such projects, while other colleges also have several EU supported initiatives.

Prof. Julius Okuni

One of the projects showcased was PREPARE TID, a partnership aimed at developing rapid diagnostic technologies for emerging and re emerging infectious diseases.

Prof. Julius Okuni, Associate Professor of Veterinary Pathobiology and Molecular Diagnostics at Makerere University, said the project brings together universities, industries and other organisations from Africa and Europe.

The project is working to develop technologies that can quickly identify pathogens responsible for outbreaks such as Ebola, Rift Valley fever and Crimean Congo haemorrhagic fever.

According to Prof. Okuni, Makerere is involved in field and laboratory work to test and refine the technologies before they can be delivered to end users.

Fair provides platform for research visibility

For researchers at MakSPH, the fair also provided an opportunity to increase the visibility of ongoing research and create new connections with researchers, policymakers and potential funders.

Dr. Raymond Tweheyo, Honorary Lecturer and Senior Research Fellow in the Department of Health Policy, Planning and Management, said such exhibitions allow researchers to share their work and identify others working on related challenges.

Dr. Raymond Tweheyo and Assoc. Prof. Angelina Kakooza Mwesigye at the exhibition

He cited the CONNECT for Health project, which focuses on transforming non-communicable disease care in Uganda through collaboration with partners across several countries.

Dr. Tweheyo said exhibitions can help researchers connect with policymakers, civil society organisations and other partners who can contribute to translating research into practical solutions.

Assoc. Prof. Angelina Kakooza Mwesigye, Associate Professor and Child Neurologist at Makerere University College of Health Sciences, also emphasised the importance of exposing young people to international research opportunities.

She said the long standing Uganda Europe partnership provides opportunities for the next generation of researchers to learn, build networks and prepare for future research collaborations.

The School of Public Health’s participation highlighted the role of international partnerships in strengthening research capacity, supporting innovation and developing evidence based responses to Uganda’s public health challenges.

Allan Ainematsiko

Bachelors of Journalism and Communication

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Uganda’s Outbreak Experience Points to Strong Response Systems but Persistent Detection Gaps

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MakSPH Dean Prof. Rhoda Wanyenze, Dr. Steven Kabwama, district health officials and partners at the EPiC validation workshop on Uganda’s Ebola and Marburg outbreak responses, 6 October 2026. Makerere University School of Public Health and FHI 360 country validation workshop convened by the Meeting Targets and Maintaining Epidemic Control (EPiC) project, to examine lessons from Uganda’s response to filovirus disease outbreaks, 6th October 2026, MakSPH Auditorium, Makerere University, Kampala Uganda, East Africa.

Uganda has strengthened its ability to respond rapidly to Ebola and Marburg outbreaks once cases are confirmed, but delays in frontline detection, health worker exposure, emergency financing bottlenecks and incomplete implementation of lessons from previous outbreaks continue to undermine preparedness, a study has found.

The findings were presented today, October 6, 2026, during a country validation workshop convened by the Meeting Targets and Maintaining Epidemic Control (EPiC) project, to examine lessons from Uganda’s response to filovirus disease outbreaks. The study was undertaken by Makerere University School of Public Health and FHI 360.

Presented by Dr. Steven Kabwama, the synthesis examined Uganda’s experience with recurrent Ebola virus disease (EVD) and Marburg virus disease (MVD) outbreaks between 2000 and 2026, drawing particularly on After-Action Reviews from the 2017 Marburg outbreak and the 2019, 2022 and 2025 Ebola outbreaks. The work seeks to consolidate recurring strengths, weaknesses, innovations and lessons that had previously been documented separately.

Dr. Steven Kabwama presents findings on strengths and detection gaps in Uganda’s Ebola and Marburg outbreak responses at the EPiC validation workshop, 6 October 2026. Makerere University School of Public Health and FHI 360 country validation workshop convened by the Meeting Targets and Maintaining Epidemic Control (EPiC) project, to examine lessons from Uganda’s response to filovirus disease outbreaks, 6th October 2026, MakSPH Auditorium, Makerere University, Kampala Uganda, East Africa.
Dr. Steven Kabwama presents findings on strengths and detection gaps in Uganda’s Ebola and Marburg outbreak responses at the EPiC validation workshop, 6 October 2026.

Uganda has recorded 12 filovirus outbreaks over the 26-year period, including nine Ebola and three Marburg outbreaks, according to the research team. Among the four outbreaks examined closely were the 2017 Marburg outbreak in Kween and Kapchorwa, the cross-border Ebola outbreak in Kasese in 2019, the multi-district Sudan Ebola virus outbreak in 2022, and the 2025 outbreak whose index case was a health worker.

Strong systems after confirmation

Across the outbreaks reviewed, the synthesis found that Uganda has developed significant capacity to mobilise after laboratory confirmation. National and district task forces and technical response structures are activated quickly, supported by strong laboratory capacity, established coordination mechanisms and increasingly sophisticated surveillance systems.

The country has also built laboratory capacity around the Uganda Virus Research Institute, mobile laboratories, genomic sequencing, sample referral systems and the Results Dispatch System. Digital surveillance tools, Village Health Teams, survivor champions and established national and district coordination structures have further strengthened response capacity.

Detection remains a weak point

However, the findings point to a critical problem before confirmation: recognising a possible outbreak early enough.

For outbreaks originating within Uganda, the synthesis found that the period between a patient’s first presentation and confirmation ranged from nine to 27 days. This the study found is linked to low clinical suspicion and weaknesses in screening. Other recurring challenges included delayed access to emergency financing, infections among health workers, disruptions to essential health services, community mistrust and stigma, and limited follow-through on recommendations from previous After-Action Reviews.

Opening the workshop, the Dean, Prof. Rhoda Wanyenze, said understanding these delays requires going beyond identifying broad weaknesses to examining where response systems fail in practice.

“We can identify a broad challenge such as delayed detection from the literature, but your experience on the ground can help us understand the specific factors that create that challenge,” Prof. Wanyenze said while addressing district health officials from across the country.

MakSPH Dean Prof. Rhoda Wanyenze (right) speaks with Dr. Andrew Ocero of FHI 360 during the EPiC validation workshop on Uganda’s Ebola and Marburg outbreak responses, 6 October 2026. Makerere University School of Public Health and FHI 360 country validation workshop convened by the Meeting Targets and Maintaining Epidemic Control (EPiC) project, to examine lessons from Uganda’s response to filovirus disease outbreaks, 6th October 2026, MakSPH Auditorium, Makerere University, Kampala Uganda, East Africa.
MakSPH Dean Prof. Rhoda Wanyenze (right) speaks with Dr. Andrew Ocero of FHI 360 during the EPiC validation workshop on Uganda’s Ebola and Marburg outbreak responses, 6 October 2026.

“When we begin looking for solutions, we need to be able to target the actual problems rather than simply identifying broad challenges.”

The workshop brought together partners and colleagues from districts, including people directly involved in outbreak response, to validate the synthesis against frontline experience. Prof. Wanyenze noted that published literature, scientific papers and response reports cannot capture every operational reality, making practitioner experience essential to understanding where delays occur and what interventions have worked. Remarks validation workshop

Turning outbreak experience into continuous readiness

Among the priority actions proposed are stronger screening and alert systems for earlier detection; ring-fenced emergency financing and more reliable responder payment systems; routine infection prevention and control training; stronger occupational protection for health workers; continued investment in laboratories and genomic sequencing; and preparedness extending beyond districts traditionally considered outbreak hotspots. The study also recommends stronger community engagement and a formal mechanism to track and finance implementation of recommendations from After-Action Reviews.

Participants contribute to discussions on Uganda’s Ebola and Marburg outbreak responses during the EPiC validation workshop, 6 October 2026. Makerere University School of Public Health and FHI 360 country validation workshop convened by the Meeting Targets and Maintaining Epidemic Control (EPiC) project, to examine lessons from Uganda’s response to filovirus disease outbreaks, 6th October 2026, MakSPH Auditorium, Makerere University, Kampala Uganda, East Africa.
Participants contribute to discussions on Uganda’s Ebola and Marburg outbreak responses during the EPiC validation workshop, 6 October 2026.

Dr. Andrew Acero, Director of the EPiC project at FHI 360’s Uganda Office said the central challenge is ensuring that experience accumulated during successive outbreaks translates into lasting institutional capacity.

“The real value lies in ensuring that what we learn changes what we do. Our findings should inform policy, shape guidelines and training, strengthen systems and ultimately improve practice.”

He noted that preparedness cannot begin only after an emergency has been declared, but must be built through sustained relationships, systems and capacity before outbreaks occur. Remarks validation workshop

The EPiC project is led by FHI 360 with core partners including Right to Care, Palladium and Population Services International.

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Betty Kyakuwa
Betty Kyakuwa

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Uganda’s HIV Treatment Gains Bring the Youth Gap into Focus

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Stakeholders pose for a group photo at the UPHIA preliminary results release on 1st October 2026. Released of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.

Uganda’s latest national HIV survey reveals lower viral suppression among adolescents and young adults living with HIV than among older adults, even as the country records substantial improvements in controlling the virus. The findings come from Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey examining HIV prevalence and whether people living with the virus know their status, receive treatment, and achieve viral suppression.

Releasing the preliminary UPHIA 2025 findings at the Uganda Media Centre on 1 October 2026, Minister of Health Hon. Dr. Chris Baryomunsi called for earlier prevention and testing, particularly among adolescent girls and young women, alongside support for treatment adherence. “We must reach out to the young people, ensure that they have information, they test, take treatment, and adhere to the treatment guidance,” he urged.

Hon. Baryomunsi recalled how fear had discouraged testing during his university years: “I remember when we were at university, we went for testing at the university hospital. We sat there for three hours. Some of us left without even testing because it was scary.” Today, he explained, “even if you test HIV positive, you can be initiated on treatment, and you live normally like the rest of those who don’t have HIV.”

Minister of Health Hon. Dr. Chris Baryomunsi urges earlier HIV testing and stronger treatment adherence among young people at the UPHIA 2025 preliminary results release, Uganda Media Centre, 1 October 2026. Released of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
Minister of Health Hon. Dr. Chris Baryomunsi urges earlier HIV testing and stronger treatment adherence among young people at the UPHIA 2025 preliminary results release, Uganda Media Centre, 1 October 2026.

UPHIA 2025 was locally led under the Ministry of Health’s overall leadership, with Makerere University School of Public Health serving as the prime implementer, a role ICAP at Columbia University held in the previous two surveys. The Uganda Bureau of Statistics led sampling, while the Uganda Virus Research Institute and National Health Laboratory and Diagnostic Services led laboratory operations. Regional referral hospitals and local governments supported implementation, and the U.S. government provided US$10 million through PEPFAR, along with technical assistance from the U.S. CDC.

UPHIA collected data from July to September 2025 among people aged 15 and above, including those outside routine treatment services. Of 6,283 eligible households, 94.4% completed interviews. Researchers interviewed 13,801 people and tested 13,477 for HIV.

Testing followed Uganda’s national algorithm, with laboratory confirmation of positive samples, viral-load measurement, and checks for antiretroviral medicines to establish treatment use. Researchers weighted the estimates to account for the sampling design. Participants received counselling and results, and those who tested positive were referred for treatment.

Hon. Baryomunsi thanked participants and their families for welcoming survey staff and contributing their time, information and samples, without which the national evidence would not have been available.

UPHIA field staff sensitise community members about the survey ahead of data collection in July 2025. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
UPHIA field staff sensitise community members about the survey ahead of data collection in July 2025.

National progress and the youth gap

The survey estimated HIV prevalence, which means the proportion of people living with HIV, at 5.9% among those aged 15 and above, corresponding to about 1.496 million people in this age group nationwide. Prevalence was 7.3% among women and 4.1% among men, ranging from 1.3% in Karamoja to 8% in the South Western region.

Among people aged 15 and above living with HIV, 86% had achieved viral suppression, meaning a low amount of HIV in the blood, measured in UPHIA as fewer than 1,000 copies per millilitre. Suppression stood at 69.3% among adolescents and young adults aged 15–24 living with HIV, compared with 89.9% among those aged 50 and above. These estimates cover people living with HIV regardless of whether they know their status or receive treatment.

A UPHIA field worker collects a blood sample from a survey participant in July 2025. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
A UPHIA field worker collects a blood sample from a survey participant in July 2025.

HIV prevalence among people aged 15–24 was 1.5%, including 2% among young women and 1% among young men. Among young women, prevalence was 1.3% at ages 15–19 and 2.8% at ages 20–24. These differences support attention to earlier prevention and testing, although they do not establish when infections occurred.

The highest prevalence estimates occurred among middle-aged adults: 15.7% among women aged 40–44 and 11.7% among men aged 45–49. Lower suppression among young people therefore requires attention alongside the higher HIV prevalence among middle-aged adults. Comparing the same age group across both surveys, viral suppression among people aged 15–64 increased from 74.9% in 2020–21 to 86.1% in 2025, while HIV prevalence remained at 5.9%.

UPHIA 2025 findings show HIV prevalence by age, sex and region among people aged 15 and above, with the highest estimates among middle-aged adults and in the South Western region. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
UPHIA 2025 findings show HIV prevalence by age, sex and region among people aged 15 and above, with the highest estimates among middle-aged adults and in the South Western region.

Diagnosis and the path to 2030

The treatment results identify diagnosis as the main national gap. Among people aged 15 and above living with HIV, 85.3% knew their status. Of those aware, 99.1% were receiving treatment; among those receiving treatment, 96.5% had achieved suppression.

The 95-95-95 targets aimed for 95% of people living with HIV to know their status, 95% of those diagnosed to receive treatment, and 95% of those receiving treatment to achieve viral suppression by 2025. Among people aged 15 and above, Uganda exceeded the treatment and suppression targets, while diagnosis remained below target. UNAIDS’s Global AIDS Strategy 2026–2031 retains these targets towards ending AIDS as a public health threat by 2030.

According to WHO, viral suppression protects health and helps prevent HIV transmission. Uncontrolled HIV weakens the immune system, increasing the risk of serious illness. With continued treatment as prescribed, sexual transmission risk is negligible when HIV remains suppressed but detectable, and zero when undetectable. The Uganda AIDS Commission estimated over 34,000 new HIV infections in 2025, underscoring the importance of early diagnosis, timely treatment, and sustained suppression alongside other prevention measures.

Then Minister of Health Hon. Dr. Jane Ruth Aceng flagged off UPHIA 2025 field teams in Kampala on 29 May 2025 to generate evidence guiding Uganda’s HIV response towards ending AIDS as a public health threat by 2030. The Ministry of Health-led survey is implemented with technical support from MakSPH and partners. Makerere University School of Public Health (MakSPH) reflection on long and productive partnership with the people and Government of the United States, spanning more than 35 years. Kampala Uganda, East Africa.
Then Minister of Health Hon. Dr. Jane Ruth Aceng flagged off UPHIA 2025 field teams in Kampala on 29 May 2025 to generate evidence guiding Uganda’s HIV response towards ending AIDS as a public health threat by 2030.

The demographic stakes are substantial. People aged 15–24 constituted 21.2% of Uganda’s population in the 2024 census. The country’s Fourth National Development Plan, covering 2025–2030, prioritises a healthy, knowledgeable, skilled and productive population and reducing HIV through primary health care. Protecting young people’s health, therefore, supports their participation in education, work, and national development; UPHIA helps identify where services need greater attention.

Turning evidence into action

The study’s conclusions identify three priorities: sustain treatment outcomes, find people unaware of their status, and improve suppression among younger people. Permanent Secretary Dr. Diana Atwine connected the findings to the Ministry’s planning.

“We do believe that these results are a true reflection of what is happening in our country as far as the HIV status is concerned, and we do believe that it will give us a very clear direction and the roadmap that we are going to take in the next five years to target and to get our targets achieved.”

Ministry of Health Permanent Secretary Dr. Diana Atwine explains how UPHIA findings will guide the Ministry’s planning at the preliminary results release, Uganda Media Centre, 1 October 2026. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
Ministry of Health Permanent Secretary Dr. Diana Atwine explains how UPHIA findings will guide the Ministry’s planning at the preliminary results release, Uganda Media Centre, 1 October 2026.

Acting on these priorities requires funding for services and research. Hon. Baryomunsi outlined plans to target resources where needs are greatest, strengthen district services and align partner support with government priorities. Responding to journalists’ questions, he noted the government’s intention to increase domestic funding for the HIV response, including research.

“The HIV/AIDS response, including research and surveys such as this one, has largely been funded by partners in the past. The government of Uganda is committed to allocating more resources from our domestic budget to support the response and research,” he noted.

For the first time in the UPHIA series, the survey assessed selected noncommunicable disease indicators among people aged 15 and above: 15.5% had elevated blood pressure, 24.8% were overweight or obese, and 0.9% had raised random blood glucose. These screening findings align with the Ministry’s integration agenda and Hon. Baryomunsi’s call to bring HIV and chronic care services together to address people’s wider health needs.

Speaking at the release of the preliminary results, U.S. Embassy Chargé d’Affaires Mikael (Mika) Cleverley described UPHIA 2025 as the first Population-Based HIV Impact Assessment worldwide fully led and implemented by the country itself.

U.S. Embassy Chargé d’Affaires Mikael (Mika) Cleverley highlights Ugandan leadership and U.S. support for UPHIA 2025 at the preliminary results release, Uganda Media Centre, 1 October 2026. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
U.S. Embassy Chargé d’Affaires Mikael (Mika) Cleverley highlights Ugandan leadership and U.S. support for UPHIA 2025 at the preliminary results release, Uganda Media Centre, 1 October 2026.

“The study was led by Ugandan scientists, Ugandan managers, Ugandan public servants, Ugandan field teams, from design to data collection to analysis. And this is what two decades of focused strategic U.S. foreign investments in the public health sector was meant to produce, is to reinforce Ugandan leadership and Ugandan-led efforts.”

At the survey launch on 29 May 2025, MakSPH Dean Prof. Rhoda Wanyenze highlighted the partnership’s contribution: “The partnership between Makerere University and CDC has not only helped build national capacity in surveillance and epidemiology, but has also strengthened our ability to lead high-quality, large-scale national surveys.”

MakSPH Dean Prof. Rhoda Wanyenze speaks during the UPHIA 2025 launch in Kampala, highlighting MakSPH’s contribution to Uganda’s public health response through research, evidence and technical guidance. Makerere University School of Public Health (MakSPH) reflection on long and productive partnership with the people and Government of the United States, spanning more than 35 years. Kampala Uganda, East Africa.
MakSPH Dean and UPHIA 2025 Principal Investigator Prof. Rhoda Wanyenze highlights Uganda’s capacity to lead national surveys at the survey launch on 29 May 2025.

The Dean added: “After two decades of joint work, we are proud that UPHIA is now a fully Ugandan-led effort. This is critical to the sustainability of the skills and knowledge generation to inform our local response.”

UPHIA 2025 shows how far Uganda’s HIV response has advanced and where gaps remain. As the country works towards ending AIDS as a public health threat by 2030, reaching young people with testing, treatment, and continued care will be essential to extending those gains.

MakSPH researchers, including UPHIA 2025 Activity Lead Prof. Frederick Makumbi and Project Director Dr. Sam Biraro, converse at the preliminary results release, Uganda Media Centre, 1 October 2026. Release of preliminary findings of the 2025 Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey that provides a current picture of the country’s HIV response and selected non-communicable disease indicators, Ministry of Health-overall leadership, Makerere University School of Public Health (MakSPH)-prime implementing organisation, working with UVRI, UBOS, regional referral hospitals and local governments. Funded by PEPFAR through the U.S. CDC, 1st October 2026, Uganda Media Centre, Kampala Uganda, East Africa.
MakSPH researchers, including UPHIA 2025 Activity Lead Prof. Frederick Makumbi and Project Director Dr. Sam Biraro, converse at the preliminary results release, Uganda Media Centre, 1 October 2026.

Read the full UPHIA 2025 summary results here:

UPHIA 2025 SUMMARY SHEET

John Okeya

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