Veterinary & Biosecurity
Mak, Alfasan Sign Anti-Tick Vaccine Production MoU
Makerere University on Friday 19th March, 2021 signed a Memorandum of Understanding (MoU) with Alfasan Uganda Limited to facilitate production of test batches of the Anti-Tick Vaccine developed by the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB). The MoU was signed on behalf of Makerere University by the Vice Chancellor, Prof. Barnabas Nawangwe and on behalf of Alfasan by the Managing Director Dr. Stephen Birungi. The Principal CoVAB-Prof. John David Kabasa, Anti-Tick Vaccine Initiative Principal Investigator (PI)-Dr. Margaret Saimo-Kahwa and Acting (Ag.) Manager Intellectual Property Management Office (IPMO)-Canon Goddy Muhumuza signed as witnesses.
The Anti-Tick Vaccine Initiative is hosted under the Centre for Biosecurity and Global Health, CoVAB. According to the Prof. Kabasa, the Centre was one of the milestones endorsed by the University when the then faculty to college transition was proposed. “I am happy to report that the Centre is being vigorously supported by the Government to undertake activities of vaccine development together with other scientists.”
He thanked the Vice Chancellor always taking keen interest in the multidisciplinary programmes undertaken by the college with a view improving the livelihoods of both small and large scale livestock farmers. He equally lauded the CoVAB scientists for their efforts to develop the Anti-Tick Vaccine and stakeholders such as the Africa Institute for Strategic Animal Resource Services and Development (AFRISA), Centre of Tropical Medicine and the Ruth Keesling Wildlife Health, Research and Outreach Centre (RK_WHERE) for their support.
Unveiling the research challenge and solution, the PI Dr. Margaret Saimo-Kahwa noted that ticks as vectors for diseases like East Coast Fever are an economic threat to farmers with herds of exotic breeds, their crosses and increasingly, local breeds raised in a tick-free environment. Furthermore, common tick species in Uganda have developed resistance to acaricides used in spraying as a method of their control. This resistance is further exacerbated by acaricide contamination of the environment, leading to residues in animal products like milk and meat, which have implications on human health.
“Therefore, alternative methods like anti-tick vaccines that reduce the use of acaricides are urgently needed to protect the livestock sector that plays a role in poverty reduction and contributes at least 3.2% to Uganda’s GDP, which is equivalent to about 1 Trillion Uganda Shillings” said Dr. Saimo-Kahwa.
The efficacy of any innovation is measured by how well it has worked elsewhere. The Anti-Tick Vaccine Initiative therefore sought inspiration from Australia, where the first anti-tick vaccine was developed in the 1980s as well as Cuba where the vaccines have been used successfully for over 20 years. Gleaning further from Brazil, the team used biotechnology approaches to develop antigens that can target the ticks in Uganda.
“Testing of these molecules under laboratory conditions with funding from the Government of Uganda has been done” remarked the Principal Investigator before adding, “The next step is to test these molecules in clinical trials. However, the molecules should be manufactured under Good Manufacturing Practice (GMP) and not under laboratory conditions.”
Dr. Saimo-Kahwa at this point thanked the President, H.E. Yoweri Kaguta Museveni, whose advice led the research team to the GMP-certified Alfasan Uganda Limited. “These negotiations have been fruitful, leading to the drafting of a memorandum of understanding for production of test batches of the potential vaccine, with funding from Government of Uganda.”
Dr. Stephen Birungi a Makerere University alumnus from CoVAB was all praises for his alma mater and commended Prof. Barnabas Nawangwe for ushering in era of innovation in the short time he has served as Vice Chancellor. “If we are seeing a threat to the livestock industry, we need to act now to save the 20-30% of Uganda’s 15million head of cattle that we lose annually due to tick-borne diseases.”
He reassured all present that Alfasan, a private company certified for the production of veterinary biologicals, was fully committed to improving the livelihood of Ugandan livestock farmers by partnering with the Government of Uganda and institutions such as Makerere University.
“Alfasan as a factory that was born out of partnership between Uganda and Holland is ready to give the facilities that will convert this beautiful innovation from Makerere; once again proving that Makerere is not just a theoretical teaching institution but is ready to bring out those products that can change lives in our country” affirmed Dr. Birungi.
He thanked Makerere University for recognizing the need to produce homegrown vaccines, noting that imported batches tend become less efficacious after multiple applications due to varying protein compositions of the ticks in countries where the remedies originate and Uganda.
“It is therefore important that Government doubles the effort to support CoVAB and Makerere University so that we don’t only stop at this solution but go out and solve even bigger problems using research that has been proven such as this anti-tick vaccine” Dr. Birungi added.
Makerere University is home to a number of innovations, whose number keeps growing thanks to generous funding from the Government and other partners. In recognition of the need to translate these innovations into commercially viable products, the University introduced an Intellectual Property Management Office and appointed Canon Goddy Muhumuza as Ag. Manager. Guiding the MoU signing ceremony, Canon Muhumuza, who also doubles as Principal Legal Officer, made specific mention of the clause on “Ownership” clarifying that Makerere University shall own the patent of the vaccine.
“A new dawn is setting on Makerere University. Makerere University is becoming a truly international research university,” commenced the Vice Chancellor as he made closing remarks following the brief MoU signing and exchange ceremony.
He thanked Dr. Saimo-Kahwa for her great work and mentorship as shown by the constitution of her team, mainly made up of young people. The team is made up of Scientists; Dr. Olaho Mukhani William, Dr. Kokas Ikwap, Dr. Mukiibi Herbert, Dr. Ochwo Sylvester, Dr. Musadha Zachary and Mr. Peregrine Sebulime.
In order to study the life and breeding cycles of ticks, the Initiative included a specialist (Acarologist), Mr. Charles Ssekitto. Technicians who form part of the team include; Mr. Geoffrey Ssentamu, Mr. Nalumenya David, Ms. Namubiru Sarah and Mr. Abubaker Musoba. Mr. Gerald Brooks Musinguzi is in charge of Communication while Ms. Kaudha Rose is the Administrator.
The Vice Chancellor noted that the capacity to develop vaccines was evidence of attaining to the highest levels of research capacity and expressed great pride to learn that the team was completely Ugandan. He thanked the Government of Uganda for the heavily investing in research at Makerere University and reminded staff of their obligation to give back to the taxpayers by providing good accountability.
“I must thank the leadership of the college for the great work they are doing. Professor Kabasa is passionate about Makerere and Uganda and what we should be doing to develop our country” remarked Prof. Nawangwe.
Results from the trials conducted so far showed that the overall efficacy of the vaccine candidate proteins was 86% for R appendiculatas (the brown ear tick) that transmits East Coast Fever (ECF) and 53% for R decoloratus that transmits Babesiosis. “If this vaccine can reduce the burden of tick borne diseases, we will have through one single innovation made a huge contribution to solving one of Uganda’s biggest problems.”
Prof. Nawangwe thanked Alfasan Uganda Limited for being pioneers in implementing academia-private sector collaboration. “As we come up with more innovations and move towards being a research-led University, it is inevitable that we have to work with the private sector, and I thank Managing Director for this gesture… you are a good alumnus.”
This MoU marks the beginning of a long and mutually beneficial partnership between academia and the private sector. The Anti-Tick Vaccine Initiative intends to expand the immunization to include more animals and carry out a clinical trial to determine the appropriate dosage and schedule. Furthermore, the Anti-Tick Vaccine candidate proteins offer more opportunities to include other candidate vaccine proteins of other cattle diseases into the combination.
The event was moderated by the Principal Public Relations Officer, Ms. Ritah Namisango and the Communication Officer CoVAB, Mr. Gerald Brooks Musinguzi.
Article by Public Relations Office
Sekajja Agro Farms Ltd (SAF), a fully integrated poultry enterprise located in Buyuki Nama Sub-County, Mukono District, has initiated strategic discussions with Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) to establish a Graduate Trainee partnership. This collaboration is designed to bridge the persistent gap between academic instruction and practical industry experience by offering final-year students and recent graduates immersive training across the entire poultry value chain.
At a meeting held at CoVAB, the SAF team, led by Dr. Abu Mayanja, the Chief Operations Officer SAF, and the staff of the Department of Livestock and Industry Resources (LIR), a range of operations where the students would benefit were explained, ranging from feed mill production and hatchery management to broiler farming, outgrower coordination, and abattoir services, providing a rich environment for experiential learning. Dr. Abu said the initiative will not only enhance graduate employability but also foster innovation and research, and build technical capacity in Uganda’s poultry sector, while promoting knowledge exchange and entrepreneurial thinking among young professionals. Dr. Mayanja highlighted the significant human resource gap in Uganda’s poultry industry, noting that most workers acquire skills informally on the job. To address this challenge, the partnership will offer final-year students and recent graduates a six-month comprehensive training program, combining mentorship with hands-on experience across SAF’s integrated poultry operations from feed production and hatchery management to broiler farming and processing.
Dr. Sylvia Nalubwama, along with other CoVAB staff, emphasized the strategic importance of the proposed Graduate Trainee partnership with Sekajja Agro Farms Ltd (SAF). The team highlighted that the initiative aligns well with Makerere University’s broader mission to provide education that meets societal needs, especially through practical, skills-based training. The two parties agreed to formalize the partnership following the established process, starting at the departmental level through the School of Veterinary Medicine and Animal Resources (SVAR), and concluding with approval of the Memorandum of Understanding by University Management. They also agreed that, due to the urgent workforce gaps in the poultry industry, they would begin immediate engagement and move forward with preliminary activities, including reaching out to interested students and planning the program, even while formalities are still being finalized.
Among some of the terms of the engagement is providing student facilitation, including rent, internet access, and meals, while emphasizing the importance of attitude, adaptability, and willingness to learn. Students will be selected through a merit-based application and interview process. The meeting also spoke of the need for collaboration with BTVET institutions, certification for trainees, and aligning academic programs with industry expectations.
Representatives of the final-year students in attendance expressed keen interest in the Graduate Trainee program and raised pertinent questions regarding remuneration and post-training employment opportunities. In response, representatives from Sekajja Agro Farms Ltd (SAF) acknowledged the importance of financial incentives but emphasized that the true value of the program lies in the unique exposure it offers to the commercial and operational aspects of poultry production. They assured students that the six-month training module is designed to equip them with critical skills, industry insights, and entrepreneurial competencies that are essential for driving growth and innovation within Uganda’s poultry sector.
Veterinary & Biosecurity
CoVAB Prepares Future Educators with One Health Skills to Address Zoonotic and Climate Risks
On Monday, 22nd September 2025, the Department of Biosecurity, Ecosystems and Veterinary Public Health (BEP) at the College of Veterinary Medicine, Animal Health and Biosecurity (CoVAB), Makerere University, launched a four-day intensive training program aimed at equipping Uganda’s next generation of educators with foundational knowledge in One Health. This initiative seeks to foster interdisciplinary understanding among future teachers, emphasizing the interconnectedness of human, animal, and environmental health in addressing emerging public health challenges.
The initiative, titled “One Health Training of Uganda’s Next Generation of Teachers,” targets selected third-year education students from Makerere University, Kyambogo University, Uganda Christian University (UCU), and Kabale University, along with newly graduated teachers from across the country. The training is one of the activities of the broader Capacitating One Health in Eastern and Southern Africa (COHESA)project, a regional program spanning 12 countries aimed at strengthening interdisciplinary collaboration and promoting integrated approaches to health education and practice.
Prof. Clovice Kankya, Head of the BEP Department at CoVAB and Principal Investigator of the COHESA project in Uganda, underscored the transformative impact of the training, describing it as a strategic investment in the nation’s future health resilience. He noted that by equipping educators with foundational knowledge in One Health, Uganda is fostering a sustainable network of informed leaders capable of influencing both formal education systems and grassroots communities. These teachers will not only embed One Health principles into their curricula but also serve as local ambassadors and champions for improved sanitation, climate adaptation, and disease prevention within their communities.
“This is more than a training,” Prof. Kankya remarked. “It’s a movement to embed One Health thinking into the social fabric of Uganda, given that educators are trusted voices in society. When they grasp the interconnectedness of human, animal, and environmental health, they become powerful catalysts for behavioral change and community-driven action.”
He emphasized the pivotal role of teachers as agents of change, stressing that One Health, a multidisciplinary approach integrating human, animal, and environmental health, is vital for addressing today’s complex health challenges. Despite its growing global relevance, he observed that the concept of One Health remains largely underrepresented in Uganda’s education and public health sectors. This gap, he argued, makes the involvement of teachers especially critical, as they can serve as catalysts for a multiplier effect, extending the reach and impact of One Health principles across both formal education systems and local communities.
Prof. Clovice Kankya further highlighted that the ripple effect of empowering teachers will extend beyond schools, reaching homes, villages, and regional networks. In doing so, the initiative aims to build a generation of citizens who are not only aware of health risks but are also equipped to respond collaboratively and sustainably.
The trainees, drawn from diverse teaching disciplines, received instruction in key areas such as an introduction to One Health principles, zoonotic diseases and outbreak investigation, risk communication strategies, community engagement, and exit protocols, among others. Facilitators from AFROHUN and CoVAB were carefully selected for their expertise in outbreak response, strategic communication, and community-based education. The curriculum is enriched with social science perspectives to strengthen community entry approaches and promote culturally sensitive messaging, ensuring that participants are well-equipped to engage effectively with local populations.
Veterinary & Biosecurity
CIMTRADZ Founders Convention Reflects on Achievements and Sets a Bold Agenda for Global Biosecurity
In a strategic gathering at Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ) held its Founder’s Convention to reflect on its 12-year journey and unveil its ambitious next chapter: the Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA). The event, hosted under the School of Biosecurity, Biotechnical and Biomolecular Sciences (SBLS), brought together scientists, students, and strategic partners from across Uganda and beyond. The convention served as both a retrospective and a launchpad, celebrating CIMTRADZ’s achievements while setting a bold agenda for MAGBBA’s future.
Ms. Brenda Nakazibwe, Team Lead for the Pathogen Economy at the Science, Technology and Innovation (STI) Secretariat, delivered an address on behalf of Hon. Dr. Monica Musenero, Minister of Science, Technology, and Innovation. She commended the brains and effort behind CIMTRADZ for their relentless efforts in implementing research and training programs initially supported under the Presidential Initiative on Science and Technology that set the pace for the numerous achievements realised to-date.
Nakazibwe outlined Uganda’s strategic roadmap for harnessing science and innovation to drive national development. She revealed that since March 2022, the STI Secretariat has operated through eight specialized bureaus focused on mobility, export promotion, and productivity acceleration. “Our mandate is to coordinate the ecosystem,” Nakazibwe emphasized, “bringing together academia, media, and the private sector to ensure science leads us to another level.”
While emphasisng the commitment of continued support to the academia in finding solutions to societal challenges, Nakazibwe also spotlighted Uganda’s prioritized industrial value chains, which include ICT, artificial intelligence, infrastructure innovation, aeronautics, and space science. She stressed that science must be a tool to combat poverty and unemployment, aligning with the goals of National Development Plan III.
Representing Vice Chancellor Prof. Barnabas Nawangwe, Prof. Mukadasi Buyinza praised the university’s growing network of research centers, some of which have attained Level 5 status as centers of excellence. He emphasized that the transition from the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ) to the proposed Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA) signals a strategic shift toward sustainability and broader impact.
“In the face of pandemics and epidemics, the world is counting on scientists,” Prof. Buyinza said. “This is no longer a concern confined to laboratories, but it’s a matter of national survival.”
He called on Uganda’s scientific community to develop a comprehensive national inventory of pathogens, stressing that biosecurity must be a shared responsibility across sectors. He also commended the movement of Makerere’s academic talent into government and private agencies, describing it as a positive extension of the university’s influence.
“We are in the Fourth Industrial Revolution,” he noted, urging researchers to harness their expertise to address pressing health and development challenges. “Collaboration and cooperation are no longer optional but are essential.”
Prof. Buyinza concluded by pledging institutional support for scientific initiatives that translate into tangible products and services, reinforcing Makerere’s role as a driver of innovation and societal transformation.
During the convention Prof. John David Kabasa delivered a powerful message on the future of biosecurity and bioeconomy, calling on scientists to take the lead in safeguarding society against biological threats. Prof. Kabasa emphasized the urgent need to protect both human and animal populations from emerging pathogens. He described biosecurity and bioeconomy as critical pillars for national resilience and global competitiveness.
“We are living in an era of insufficiency,” Prof. Kabasa stated, “where bio threats are no longer distant possibilities but immediate challenges demanding coordinated action.”
He commended Makerere University for its visionary leadership and the platform it has provided to advance scientific research and innovation. He also acknowledged the Government of Uganda for its substantial investments across institutions, which he said have laid the foundation for transformative progress.
Prof. Kabasa stressed the importance of capacity building and value amplification, and called on universities and schools to equip learners with skills that enhance the value of biological assets and foster entrepreneurial thinking.
Prof. Kabasa however, he expressed concern over the persistence of outdated ideologies, weak innovation culture, and limited Pan-African collaboration. To address these gaps, he advocated for a culture of collaboration across higher education, research, and service delivery.
“Scientists hold the key to societal transformation,” he said, urging them to embrace their responsibility and develop solutions to pressing challenges.
Prof. M. Kaneene of Michigan State University delivered an inspiring presentation that underscored Uganda’s growing role in global biosecurity and infectious disease preparedness. Speaking as one of the founding mentors of the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ), Prof. Kaneene reflected on the initiative’s journey and its far-reaching impact. He highlighted a Special Issue of a scientific journal featuring four foundational papers that helped catalyze new projects not only in Uganda but across Africa and beyond. “Centers like CEBIGH give CoVAB a unique niche in addressing regional and global biosecurity challenges,” Prof. Kaneene said, emphasizing the importance of research and training in tackling emerging and reemerging infectious diseases.
He urged stakeholders to build on past achievements and expand the center’s influence through targeted programs such as short courses and summer training initiatives. With Uganda poised to take a leadership role, he stressed that biosecurity must remain a national priority.
The Principal of the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Prof. Frank Norbert Mwiine, represented by Prof. Savino Biryomumaisho reflected on the consortium’s decade-long impact. He noted that CIMTRADZ had significantly contributed to the expansion of the former Faculty of Veterinary Medicine, particularly under the School of Biosecurity, Biotechnology, and Laboratory Sciences.
“CIMTRADZ has been instrumental in shaping our infrastructure and academic programs,” Prof. Mwiine said. He highlighted key developments including the central laboratory, animal research facility, biomarker and diagnostic facility, and the Centre for Biosecurity and Global Health. He also pointed to the launch of advanced degree programs,Master’s and PhDs,that have created new opportunities for staff and students to pursue higher education and research excellence.
“These achievements align perfectly with Makerere University’s vision of being a thought leader in knowledge generation for societal transformation,” he added. Prof. Mwiine cited vaccine development as one of the tangible outcomes of the consortium’s work and expressed optimism about the next phase of the initiative, which transitions into the Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA).
Dr. Claire Mack Mugasa, Dean of the School of Biotechnical and Laboratory Sciences (SBLS), presented an overview of the school’s mandate in biosecurity, biosafety, and biomedical sciences. “Our laboratories are not just teaching spaces, they are hubs of innovation shared across departments, schools, and colleges,” Dr. Mugasa said. She emphasized the importance of partnerships with sister universities in Uganda and abroad, noting that collaboration is key to building capacity and driving scientific progress.
Following her remarks, Dr. Enoch Matovu, Director of the Centre for Global Health, addressed the urgent need for preparedness in the face of emerging and re-emerging diseases. He cited the 2022 chickenpox outbreak as a wake-up call for the region’s health systems.
“The establishment of this research centre was a strategic response to such threats,” Dr. Matovu said. “Through programs like vaccinology, we are equipping scientists to protect both human and livestock ecosystems.”
He praised the founding team behind the Centre for Biosecurity and Global Health for their vision and dedication, which have propelled CoVAB to the forefront of regional biosecurity efforts.
During the CIMTRADZ Founder’s Convention at Makerere University, participants celebrated a decade of achievements in biosecurity and institutional development at CoVAB. Key milestones included the establishment of a state-of-the-art research center, enhanced international collaborations, staff capacity building, and the launch of advanced academic programs. The event also highlighted cultural and academic exchanges such as summer schools, workshops, and conferences. These accomplishments reflect CoVAB’s strategic growth and its evolving role as a regional leader in biosecurity, now transitioning into the next phase under MAGBBA.
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