Child with Cerebral palsy with severe motor impairment in a wheel chair, occupational therapist is on his left and caregiver is on his right demonstrating to the therapist what the child is able to do with his right hand
The largest study on Cerebral palsy in Africa to date reveals that interventions to prevent malaria infections such as the use of insecticide-treated mosquito nets, coupled with caregiver training and support, including best feeding practices and simple measures to prevent other infections, could potentially reduce mortality in children with Cerebral palsy in this region.The study found out that the main causes of death were malaria and aneamia. The children with severe malnutrition and severe motor impairments were the most likely to die.
Cerebral palsy (CP) is a developmental disorder and the most common cause of childhood physical disability globally. CP is significantly more prevalent in low-income and middle-income countries like Uganda where the researchers noted a lower prevalence in the older (8-17 years) than younger (2-7 years) age groups as demonstrated in the findings of an earlier study conducted in 2015. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(17)30374-1/fulltext
The decline in prevalence of children with CP with increasing age in the 2015 study, led the researchers to hypothesize about the risk of premature death in these children.
In order to get a better understanding of the situation, a follow-up study was carried out at the Iganga-Mayuge Health and Demographic Surveillance Site (IM-HDSS) in eastern Uganda. Earlier in 2015, the researchers had screened 31,756 children and identified 97 (aged 2–17 years) who were diagnosed as having CP. The children with CP were followed up to 2019 and compared with an age-matched sample of the IM-HDSS general non-CP population (n=41, 319). The rates and causes of deaths in these groups were determined.
The research team found that the rate of death was 25 times higher in the CP group than the general non-CP population sample. The mean age at death among the CP group was 10•2±5•9 years and 7•2±4•8 years among the general non-CP population sample. In the CP group, females and older children (10-18 years) had higher relative risks of death in relation to the non-CP general population. Significantly, in children with CP, there was an almost 7 times risk of death in those with severe motor impairments compared to those with milder ones. In addition, those with severe malnutrition had a more than 3 times higher risk of death than children without severe malnutrition. The causes of death were from common conditions like anemia, malaria and common infections.
The results of this study, are the first of its kind to reveal the true extent of the hidden humanitarian crisis of excessive mortality in the CP child population. Severe malnutrition as one of the risk factors of excessive mortality plays a dynamic multifaceted role, partly aggravated by severe oral motor impairments which lead to chewing and swallowing problems, and the need for special foods and prolonged feeding times. Furthermore, the age pattern for mortality in children with CP confirms this study’s hypothesis with many dying when approaching school age, compared to the non-CP general population. The probable reasons for this may be attributed to caregivers eventually losing hope as these children grow older when they realize that their child will not be cured, or alternatively as a result of the minimal time provided to the child with increasing age (including during supervised feedings), which increases their vulnerability.
The higher mortality among the females may suggest a preferential treatment of boys with CP in Uganda which needs further study. Finally, regarding the causes of death, the frequent occurrence of anemia as a cause of death may signify the interplay of the conditions of underlying malaria infections and severe malnutrition in severely impaired children with feeding problems.
A multipronged approach including raising awareness about this challenge should be emphasized locally and internationally to promote the development of appropriate health and advocacy policies. Although efforts to reduce child mortality are quite evident in the recent decades, targeted interventions to reduce mortality in the CP child population, such as the use of insecticide-treated mosquito nets to prevent malaria infections, provision of easy to use, locally available nutritious foods coupled with caregiver information and support should be encouraged. Reinforcement and regular review of the existing laws and policies related to their specific requirements should be enacted. In general, further research to identify long-term risk factors and immediate causes of death in children with developmental disabilities in the region is also urgently required
These findings are to be formally published in the journal ‘PLOS ONE’ and entitled: “Excessive premature mortality among children with cerebral palsy in rural Uganda: a longitudinal, population-based study”.
Community-led innovations across Uganda are improving access to healthcare, reducing financial barriers and responding to needs that conventional services do not always reach. The Uganda Case Compendium 2026, published by the Social Innovation in Health Initiative (SIHI) Uganda Hub at Makerere University School of Public Health, documents these solutions, their results and opportunities for scale.
Established in 2017, SIHI Uganda identifies, studies and supports locally developed health innovations. By 2026, the Hub had documented 42 projects through research examining their impact, enabling factors and scalability. It has also convened seven national stakeholder workshops and established a fellowship programme that equips innovators with skills in project management, research, entrepreneurship, communication, fundraising and environmental impact assessment.
The compendium presents evidence of reach and impact. The Ishaka Health Plan has enrolled more than 5,000 people in community-based health insurance, enabling over 4,000 members to access healthcare annually. In Kiryandongo, the Opit Kic Widows Group trained 402 volunteers who have provided health information to more than 6,030 refugee and host-community households. Among people living with HIV who received group support psychotherapy, 98% were depression-free after six months. In Mayuge, two sickle cell clinics have been established, 12,500 children screened and 282 enrolled in continuing care, contributing to a reported 53% increase in enrolment.
Spanning maternal and child health, HIV, mental health, disability, gender-based violence, health financing, diagnostics and palliative care, the compendium provides evidence to inform investment, policy uptake and the responsible scale-up of locally grounded solutions.
Makerere University School of Public Health invites applications for two postdoctoral research fellowships under the ACT-PREP Project, a five-year, Africa-led initiative funded by the Global Health EDCTP3 Joint Undertaking. The project seeks to strengthen sustainable, context-responsive research capacity for epidemic preparedness and response across sub-Saharan Africa.
Responsibilities
Each fellowship is a full-time, 18-month appointment based at MakSPH in Kampala. Applicants must apply for one position only. Eligible candidates should be early-career researchers who are nationals of, or based in, sub-Saharan Africa and hold a PhD in a relevant discipline or have completed a post-Master’s Field Epidemiology Training Programme. Applicants should demonstrate a record of peer-reviewed publication and research dissemination. Experience in policy review, qualitative or mixed-methods research and stakeholder engagement is an advantage. Successful fellows will receive mentorship from senior researchers, collaborate with an international consortium of African and European institutions, and contribute to policy-relevant research on epidemic preparedness. A stipend commensurate with qualifications and experience will be provided. Applications should include a motivation letter of up to two pages, a two-page research concept, a detailed curriculum vitae with a publication list and contacts for at least two referees, and at least one recommendation letter.
Qualifications and Desirable Qualities
Eligible candidates should be early-career researchers who are nationals of, or based in, sub-Saharan Africa and hold a PhD in a relevant discipline or have completed a post-Master’s Field Epidemiology Training Programme.
How to Apply
Submit applications to recruitment@musph.ac.ug by 7 August 2026, quoting “ACT-PREP Postdoc – Position 1 or 2” in the email subject line. Interviews are expected around 14 August 2026 in Kampala.
Qualified women and applicants from under-represented groups are strongly encouraged to apply.
Download the full call for detailed requirements and application guidance.
The Makerere University College of Health Sciences (MakCHS) on July 10, 2026, welcomed senior six science students from Ngora High School and Wiggins Secondary School to an inspiring Career Fair aimed at guiding them on careers in health sciences and introducing them to the wide range of academic programmes offered by the College.
The event brought together students pursuing Physics, Chemistry, Biology (PCB) and Biology, Chemistry, Mathematics (BCM), providing them with a unique opportunity to interact with the College leadership, tour laboratories and teaching facilities, and learn first-hand about careers in medicine and other health science disciplines.
Welcoming the students, the College Principal, Prof. Bruce Kirenga, described the College of Health Sciences as one of Africa’s oldest and most distinguished medical schools, with a legacy spanning more than a century.
“We started in 1924, making us one of the oldest medical schools on the continent. You have made the right decision to visit Makerere, and we are delighted to welcome you,” he said.
Prof. Kirenga commended the school administrators and teachers for organizing the visit, noting that exposing learners to university environments early helps them make informed career choices. He explained that the College introduced the Open Day concept after receiving numerous requests from schools seeking career guidance visits.
Prof. Bruce Kirenga.
He congratulated the students for choosing science subjects, describing science as the foundation for solving society’s most pressing challenges.
“You have already made one of the most important decisions by choosing to become scientists. Even more importantly, you have chosen life sciences—a field dedicated to preserving and improving life,” he remarked.
The Principal emphasized that careers in life sciences extend far beyond medicine, encouraging students to remain open-minded as they consider their future.
“Everything that has life requires professionals to keep it healthy—from human beings and animals to crops and the environment. The opportunities are immense, including agriculture, veterinary medicine, biomedical sciences, public health and many other emerging fields.”
A section of senior six students and their students at the career fair.
He also advised students not to limit themselves to only one academic programme during university applications, recalling instances where highly qualified students narrowly missed admission because they selected only one course.
“Remain open to the opportunities available. Medicine is an excellent profession, but there are many other programmes that are equally rewarding and are shaping the future of healthcare and scientific innovation,” he said.
Prof. Kirenga further encouraged the students to embrace lifelong learning, reminding them that scientific knowledge remains valuable regardless of the career path they eventually pursue.
Addressing the students, the Dean of the School of Medicine, Prof. Annette Nakimuli, acknowledged the growing competition for admission into medical programmes and urged learners to work hard while keeping an open mind about the diverse opportunities available within health sciences.
Prof. Annettee Nakimuli.
She explained that admission into the Bachelor of Medicine and Bachelor of Surgery (MBChB) programme has become increasingly competitive due to the rising number of high-performing applicants.
“This year we witnessed unprecedented competition for government sponsorship, with many applicants scoring triple A at Advanced Level and outstanding grades at Ordinary Level. That tells you that you must prepare yourselves to excel academically,” she said.
Prof. Nakimuli noted that while many students aspire to become medical doctors, the health sector today offers numerous innovative programmes that are equally important.
“There are many programmes that parents, teachers and students are still not familiar with. Biomedical Engineering, for example, is one of the exciting fields driving the future of healthcare, yet many students overlook it because they focus only on medicine.”
Students and Teachers pose for a group photo with CHS staff.
She encouraged students to explore emerging disciplines that combine medicine, engineering, technology and research, noting that the future of healthcare increasingly depends on multidisciplinary professionals.
The Dean also introduced students to the structure of the School of Medicine, explaining that it comprises twelve academic departments and two specialised units covering a broad spectrum of clinical disciplines, including Internal Medicine, Surgery, Obstetrics and Gynaecology, Orthopaedics, Ophthalmology, Ear, Nose and Throat (ENT), Family Medicine, Anaesthesia and Critical Care, among others.
She explained that students are trained by specialists across these disciplines to become competent general practitioners before pursuing further specialization.
Prof. Erisa Mwaka, the Chair of the Department of Human Anatomy, shared with the students about the School of Biomedical Sciences (SBS). He said the school is one of the four schools that make up the Makerere University College of Health Sciences (MakCHS). As the foundation of medical education, the School provides students with a comprehensive understanding of the biological and molecular sciences that underpin modern healthcare, disease prevention, diagnosis and treatment.
Prof. Erisa Mwaka with students in one of the teaching spaces.
The School comprises several departments, including:
Human Anatomy
Biochemistry
Physiology
Pharmacology and Therapeutics
Pathology
Microbiology
Medical Illustration
The School offers undergraduate programmes such as the Bachelor of Science in Biomedical Sciences, which equips students with strong laboratory, research and analytical skills, and the Bachelor of Science in Biomedical Engineering, an interdisciplinary programme that integrates engineering, medicine and technology to develop innovative healthcare solutions.
At postgraduate level, the School offers a wide range of master’s and doctoral programmes, including Human Anatomy, Physiology, Pharmacology, Bioinformatics, Immunology and Clinical Microbiology, Health Bioethics, Medical Illustration, Pathology and other biomedical specializations that prepare graduates for careers in research, academia, diagnostics, biotechnology and the pharmaceutical industry. The school also offers a wide range of diploma courses.
Dr. Isaac Magulu Kimbowa from the Department of Pharmacology and Therapeutics (Right) and colleagues interact with the students.
Throughout the Career Fair, students interacted with faculty members, toured laboratories and learning facilities, and received guidance on university admission, academic programmes and career prospects within the health sciences.
The Career Fair forms part of the College’s broader outreach programme aimed at nurturing the next generation of healthcare professionals by exposing learners to university life and equipping them with the information needed to make informed academic and career decisions.