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Makerere University Presents Covid-19 Intervention Model

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At a press conference held today Tuesday 16th June 2020, a research team led by Makerere University presented a ‘Mathematical Model of COVID-19 dynamics in Uganda: Using a locally parameterized system to enhance intervention policies’. The aim of the research from which the model is developed was to study the dynamics of COVID-19 in Uganda and use the results to provide comprehensive forecast of the disease’ trends. The model endeavours to provide appropriate evidence-based policy support to government on the timing and nature of intervention measures.

The research team that worked on the study is led by Prof. Joseph Y.T. Mugisha, a Professor of Biomathematics (Department of Mathematics, College of Natural Sciences). Professor Mugisha is also the Principal of the College of Natural Sciences, Makerere University. Other members of the team are: Dr. Juliet Nakakawa Nsumba (Makerere University), Dr. Joseph Ssebuliba (Makerere University) Dr. Amos Ssematimba (Gulu University), and Dr. Cliff Richard Kikawa (Kabale University).

The Vice Chancellor – Makerere University, Professor Barnabas Nawangwe and the Deputy Vice Chancellor –Academic Affairs, Associate Professor Umar Kakumba attended the press conference.

In his remarks, Professor Nawangwe welcomed the press to Makerere University thanking them for informing the public about the research and innovations developed by staff and students of Makerere University. He said ‘as we all are aware, COVID-I9 is a big global challenge and Makerere as a lead research institution is working to provide solutions to the pandemic at the national, regional and global levels with our partners’. He reiterated his appreciation of the Government of Uganda for providing funds through the Makerere Research and Innovation Fund that enabled the team to undertake the study presented.

Study Conclusion

The findings of this study show that the immediately implemented measures by the Government of Uganda averted thousands of cases that would have overstretched the health system within a couple of months. Without significantly altering the current situation, measures on partial lockdowns and use of masks are insufficient to stop COVID-19 and as such the disease will remain endemic in the population. In all the assessed scenarios the disease would be wiped out in the case where there are no infected arrivals beyond the first 58 days and in this case the disease would be wiped out within 200 days.

With the worrying situation of increased reported cases in our neighbouring countries, the impact of Uganda’s interventions would be greatly affected as results show that doubling the imported cases would almost triple both the maximum number of hospitalized individuals and the number of undetected cases.

Screening of truck drivers faces a challenge of reagent limitation, imperfect test accuracy, arrival of asymptomatic and latently infected individuals that may pass as false negatives during screening as well as the porosity of some of the national borders. Thus, adoption of alternative less-risky means of essential cargo delivery (e.g., by rail and ship services) combined with quarantining of all entrants for a duration not shorter than the incubation period should be enforced.

Amidst challenges of social-economic impact of COVID-19, agitation of lifting lockdown may downplay the impact of intervention measures and the study findings highlight the importance of optimal timing and magnitude of lockdown easing. Effectively phased-out ease of lockdown needs to be well studied and executed to avoid the possibility of a second wave.

Study Recommendations

1. It is not advisable to eased lockdown by releasing 50% of susceptible population for the Ugandan situation with current 3200 hospital beds and not all are of ICU-like capacity, because within 100 days the COVID-19 related hospitalization demand would have already overwhelmed the current resources.

2. Since the consequences of hospital acquired infections go beyond merely increasing the number of cases, their mitigation should be given high priority.

3. Lifted to a 75% level, the yet-to-be detected cases in the community have potential to start a second and more disastrous epidemic wave. However, with enhanced surveillance and contact tracing, gradual easing by releasing smaller percentages of susceptible individuals from lockdown can still be safely executed sooner than the optimum 210 days for up to 75% susceptible level.

4. The issue of handling truck drivers mingling at service and testing centres at border crossings should be reinforced – preferably, government should set up treatment and isolation facilities as close as possible to the testing border points not to overwhelmed the existing regional facilities, optimize scarce handling resources and also to minimize stigma and community discontent. This would in addition reduce the time frontline workers are exposed to the risk of infection amidst lack of well-equipped ambulances

5. Since latently infected individuals can only be detected after latent period, effort should be put on obtaining information on where the drivers have been few days before arrival to understand the risk of admitting persons from high risk regions of neighbouring countries. The risk of imported cases is not only posed by those who test positive but also due to false negatives and latently infected individuals.

Article by

Ms Zaam Ssali

College of Natural Sciences

 

 

Elias Tuhereze

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Makerere Strengthens Research Ethics as Leaders Call for Reforms in Governance, Integrity, and Student Support

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High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.

By Moses Lutaaya

KAMPALA — Leaders at Makerere University have renewed calls to strengthen research ethics, governance, and integrity systems, as the institution positions itself as a leading research-driven university in Uganda and the region.

The call was made during a high-level workshop that brought together regulators, academic leaders, and research ethics committees, with a shared focus on improving coordination, efficiency, and accountability in research oversight.

Dr. Fredrick Nakwagala, Chairperson of the Accreditation Committee at the Uganda National Council for Science and Technology, commended Makerere for hosting nearly a quarter of Uganda’s approximately 40 accredited research ethics committees. He described this as a strong indicator of the university’s leadership in scientific research and training.

Dr. Fredrick Nakwagala. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Dr. Fredrick Nakwagala.

He noted that Uganda has made significant progress in building local capacity for research, moving away from reliance on foreign expertise. However, he raised concerns about gaps in institutional governance across the country, including weak research funding structures and limited administrative support in some institutions.

Dr. Nakwagala emphasized the need for standardization across ethics committees, expansion of ethical frameworks into emerging fields such as gene editing and environmental research, and stronger institutional mechanisms to address research integrity issues such as plagiarism, misuse of funds, and exploitation of students.

Echoing these sentiments, Prof. Edward Bbaale, Principal of the College of Business and Management Sciences, stressed that ethical review is central to credible and impactful research. He warned that fragmented systems lead to delays and inconsistencies, calling for harmonization and collaboration among research ethics committees.

Prof. Edward Bbaale (Standing) makes his remarks. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Prof. Edward Bbaale (Standing) makes his remarks.

Prof. Bbaale also highlighted the need for efficient and responsive review processes, continuous training in emerging research areas such as artificial intelligence and climate studies, and stronger compliance systems to meet national and international standards.

On his part, Prof. Robert Wamala, Director of the Directorate of Research Innovations and Partnerships, underscored the importance of research integrity, noting that excellence must be measured not only by output but also by ethical rigor and societal relevance.

Prof. Robert Wamala. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Prof. Robert Wamala.

He said the workshop aimed to strengthen coordination among research ethics committees, align university systems with national requirements, and enhance institutional governance through clearer guidelines, capacity building, and collaboration with regulators.

However, concerns about the impact of current systems on students were raised by Prof. Julius Kikooma, Director of Graduate Training. He revealed that many graduate students face delays in receiving feedback from ethics committees, which affects their academic progress.

Prof. Julius Kikooma. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Prof. Julius Kikooma.

Prof. Kikooma also pointed to complaints about the cost of ethics review, noting that most graduate students are self-funded and struggle to meet the required fees. He cited the example of the University of Ghana, where ethics review fees for graduate students have been waived, suggesting Uganda could consider similar reforms.

Participants at the workshop agreed that while ethical oversight remains essential for safeguarding research participants and ensuring quality, there is an urgent need to make systems more efficient, accessible, and supportive—particularly for early-career researchers.

Some of the stakeholders pose for a group photo. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Some of the stakeholders pose for a group photo.

The engagement concluded with a shared commitment to strengthen ethical standards, improve research governance, and reinforce Makerere University’s position as a hub for credible, impactful, and globally competitive research.

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Call for PhD Student Fellowships under H-DATA

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Call for PhD Student Fellowships under Harnessing Health Data Science capacity to strengthen evidence-based interventions, policy and response to the HIV/AIDS Epidemic in Uganda (H-DATA) training grant, funded by the NIH through Fogarty International Center (Grant Number D43TW013056). A collaborative effort of multiple principal investigators from Makerere University, Kampala Uganda, East Africa and University of California, San Francisco, USA.

Program overview

The Harnessing Health Data Science capacity to strengthen evidence-based interventions, policy and response to the HIV/AIDS Epidemic in Uganda (H-DATA) is a training grant funded by the NIH through Fogarty International Center (Grant Number D43TW013056). This grant is a collaborative effort of multiple principal investigators from Makerere University, Uganda and University of California, San Francisco, USA.

Grant period: 2026/2030 | Principal Investigators: David Patrick Kateete; Charles Batte;   Joyce Nakatumba, Nabende;  Efstathios Gennatas Dimitrios

H-DATA seeks to recruit qualified Ugandans for full-time PhD training in Health Data Science registered at Makerere University.

Thematic areas

Candidates should propose research studies or concepts that apply health data science approaches (AI and Machine learning) to the following thematic themes:

  • HIV risk stratification
  • Non-communicable Diseases (NCD) comorbidities in HIV [Specifically Chronic respiratory and cardiovascular diseases / hypertension]
  • HIV treatment outcomes, adherence, and long-term ART trajectories
  • Non-Canonical HIV resistance mutations
  • Digital medicine and real-world HIV data
  • Health systems and policy analytics for HIV programs

Fellowship package

The PhD fellowship support is for up to three (3) years (full-time), subject to annual performance reviews and progress milestones. Successful scholars will be registered at Makerere University and may undertake sponsored didactic health data science methods training at the University of California, San Francisco (UCSF), USA, to receive additional skills development and mentorship in health data science research.

Application Information

ELIGIBILITY

Applicants should meet the following minimum requirements:

– Master’s degree in Computer Science, Statistics/Biostatistics, Mathematics, Electrical Engineering, Bioinformatics, Epidemiology, Public Health, or another data-intensive discipline.
– Demonstrated interest and/or experience applying data science methods/technologies to health research or health systems.
– Strong quantitative or computational skills (e.g., programming, statistical analysis, machine learning, data management).
– Ugandan citizenship and commitment to advancing health data science in Africa.
– Ability to enroll in and complete full-time PhD training at Makerere University.

Note: Additional program- or department-specific admission requirements may apply.

Note: Proof of admission is not required at the time of application. However, preference will be given to applicants who have already secured admission to, or are currently registered in, a relevant PhD programme.
APPLICATION PACKAGE & SUBMISSION

Submit the following documents by email as a single application package:

– NIH Biosketch (maximum 4 pages) including relevant publications (if any).
– Cover letter (maximum 1 page).
– 2-page research concept note highlighting: research problem, specific aims, research design, and analysis plan.
– Academic transcripts and certificates for the relevant Master of Science (MSc) degree.
– Statement of purpose / motivational letter (maximum 800 words) for undertaking doctoral training in Health Data Science.
– Two letters of recommendation with up-to-date contact details from academic referees.

Email subject line (recommended): APPLICATION – Doctoral Scholarship – H-DATA PhD

File naming convention (recommended): LastName_FirstName_DocumentName (e.g., Batte_Charles_CV.pdf)

Application deadline: [February 28th 2026 by 5pm EAT]  

Program contact: [Dr Charles Batte at the address: hdatatraining@gmail.com]

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International Fellows Recruitment – Wellcome Sanger Institute

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International Fellows Recruitment - Wellcome Sanger Institute. Photo: ImageFX

The Wellcome Sanger Institute is seeking exceptional early career stage scientists to join the Institute as an International Fellow, contributing to the Institute’s scientific portfolio. Up to six fellowships available. 

The Institute is an internationally outstanding genomic research centre with over 30 core faculty teams and 1,300 employees based south of Cambridge, UK.

Fellowship Eligibility:

  • You are typically an early-mid career group leader/faculty usually up to nine years post PhD, based at a research organisation in a low- or middle-income country (LMIC). You may hold a faculty or equivalent position and are seeking to establish or strengthen your research team to develop an internationally recognised research portfolio. We also welcome applicants with equivalent experience, including those who have taken career breaks or followed non-traditional paths
  • Your main research aims should be focused on your local country and research priorities which contributes to or complements the Institute’s scientific strategy through their expertise.

Closing date: 13th February 2026

See details

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