Research

Genetic Basis of Maize Resistance to Multiple Insect Pests

Published

6 years ago

June 24, 2020

Mark Wamai

Several species of herbivores feed on maize in field and storage setups, making the development of multiple insect resistance a critical breeding target. In this study, an association mapping panel of 341 tropical maize lines was evaluated in three field environments for resistance tofall armyworm (FAW), whilst bulked grains were subjected to a maize weevil (MW) bioassay and genotyped with Diversity Array Technology’s single nucleotide polymorphisms (SNPs) markers. A multi-locus genome-wide association study (GWAS) revealed 62 quantitative trait nucleotides(QTNs) associated with FAW and MW resistance traits on all 10 maize chromosomes, of which,47 and 31 were discovered at stringent Bonferroni genome-wide significance levels of 0.05 and 0.01,respectively, and located within or close to multiple insect resistance genomic regions (MIRGRs)concerning FAW, SB, and MW. Sixteen QTNs influenced multiple traits, of which, six were associated with resistance to both FAW and MW, suggesting a pleiotropic genetic control. Functional prioritization of candidate genes (CGs) located within 10–30 kb of the QTNs revealed 64 putative GWAS-based CGs (GbCGs) showing evidence of involvement in plant defense mechanisms. Only one GbCG was associated with each of the five of the six combined resistance QTNs, thus reinforcing the pleiotropy hypothesis. In addition, through in silico co-functional network inferences, an additional107 network-based CGs (NbCGs), biologically connected to the 64 GbCGs, and differentially expressed under biotic or abiotic stress, were revealed within MIRGRs. The provided multiple insect resistance physical map should contribute to the development of combined insect resistance in maize.

Research

CARTA Fellow Tamale on Building Systems, Shaping Policy and Transforming Lives beyond the PhD

Published

3 weeks ago

October 6, 2026

Mark Wamai

Dr. Andrew Tamale, College of Veterinary Medicine, Animal Resources and BioSecurity (CoVAB), Makerere University, Kampala Uganda, East Africa. Photo. CARTA.

A PhD can spark impact that extends far beyond academia. Meet CARTA graduate Andrew Tamale, whose journey demonstrates the multiplier effect of research capacity strengthening—from helping transform doctoral training and generating evidence that informed safer fish consumption practices, to strengthening One Health approaches for outbreak preparedness in Uganda and beyond.

Read full story

Source: CARTA News & Updates Issue 105

Research

CARTA Fellow Anywar Appointed UTANA Subject Matter Expert, Talks Medicinal Plants

Published

3 weeks ago

October 6, 2026

Mark Wamai

Dr. Godwin Anywar, Department of Plant Sciences, Microbiology and Biotechnology, College of Natural Sciences (CoNAS), Makerere University. Kampala Uganda, East Africa.

Godwin Anywar, cohort 6, Makerere University, was appointed as a Subject Matter Expert on the Manuscript Technical Evaluators team of the Uganda Textbook Academic and Non-Fiction Authors Association (UTANA) on August 31, 2026. In this role, Godwin will contribute to the qualitative, academic, and pedagogical assessment of manuscripts submitted under the Capacity Building for School Books Project (CB-SP). The four-year project, implemented jointly with the Department of Teacher Education and Training Development (TETD) of Uganda’s Ministry of Education and Sports (MoES), aims to strengthen authorship and support the development of school books in Uganda’s education sector.

He was also featured in Uganda’s New Vision on July 26, 2026, in a special report on Uganda’s medicinal plants.

Source: CARTA News & Updates Issue 105

Research

Makerere Hosts TERID Hub Early Career Researchers Grant Writing Workshop

Published

3 weeks ago

October 6, 2026

Mark Wamai

The Emerging and Re-emerging Infectious Diseases (TERID) Hub continued its efforts to strengthen the capacity of 17 early career researchers (ECRs) (10 men, 7 women) on an institutional level by holding a grant writing workshop from September 8 - 11, 2026, at Makerere University, Kampala Uganda, East Africa.

The Emerging and Re-emerging Infectious Diseases (TERID) Hub continued its efforts to strengthen the capacity of early career researchers (ECRs) on an institutional level by holding a grant writing workshop from September 8 – 11, 2026, at Makerere University. The workshop, attended by 17 ECRs (10 men, 7 women), strengthened participating researchers’ capacity by equipping them with critical skills to secure competitive funding. The intensive sessions bridged the gap between innovative academic concepts and fundable proposals, focusing heavily on decoding complex funder criteria and structuring compelling narratives. Participants prioritized the CONNECT-VAX call, which closely aligns with the Hub’s core work, and formed two groups: one on vaccine research and development capacity, the other on public trust and demand for vaccines manufactured in Africa.

Through this call, the Hub engaged collaborators from West Africa (Sierra Leone) and East Africa (Kenya and Tanzania) in developing two of its grant applications. Individual concepts on leishmaniasis, leptospirosis, tuberculosis, and pharmaceutical inventory management were also advanced, bringing the total to eight proposals across four funding calls, including Makerere University Research and Innovation Fund (MAK-RIF 8), Wellcome, and WHO/TDR.

To date, the Hub’s grant writing effort has attracted over USD 700,000. The workshop reinforced the Hub’s commitment to mentoring early-career researchers and championing research in emerging and re-emerging infectious diseases.

Source: CARTA News & Updates Issue 105