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The Africa One Health Network for Disease Prevention (ADAPT), Project Launch

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A consortium of Seven Sub-Saharan countries is implementing a 5-year intervention aimed at building the capacity of improved, sustainable, and locally–led management of antimicrobial resistance (AMR) and Neglected Tropical Diseases (NTDs).

AMR is a public health problem that poses the largest threat to human health, causes death, and threatens economies especially those of developing countries in sub-Saharan Africa and South Asia.

In Uganda, the project is implemented by Makerere University in the College of Health Sciences (CHS) and the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB).  Prof. Dr. Damalie Nakanjako, the Principal CHS, and CoVAB’s Assoc. Prof. Julius Okuni are the Principal investigators.

The other sub-Saharan African states in the consortium include Senegal, Ghana, Nigeria, the Democratic Republic of the Congo, Ethiopia, and Sudan, while the other participants like Leipzig University are drawn from Germany.

At the project kickoff event held at Protea Hotel in Entebbe on Monday 12th May 2024 attended by all implementing partners, it was explained that the five-year project will investigate and sustainably develop the local capacity to identify and intervene with a diverse range of biomedical and sociocultural factors impacting human, animal, and environmental health in sub-Saharan African settings to better control AMR and NTDs.

Through a One Health Approach, the project will work with several stakeholders including Behavior scientists, Data scientists, veterinarians, Human health workers, and policymakers in developing the capacity of anti-microbial stewardship in Sub-Saharan Africa.

The project’s main tasks will include screening of AMR in humans, livestock, and poultry using surveillance and genetic mapping; investigating the relationship between helminthic infection and drug resistance bacteria to better understand the co-infection between pathogens; developing capacities for point of need diagnostics on AMR and NTDs using mobile tests for field use; identifying any changes in antimicrobial use and AMR incidences; controlling communicable disease transmission and building capacity for sustainable leadership.

Some of the participants at the kick-off event. Consortium of Seven Sub-Saharan countries; Senegal, Ghana, Nigeria, the Democratic Republic of the Congo, Ethiopia, Sudan and Uganda, Leipzig University Germany, 5-year intervention aimed at building the capacity of improved, sustainable, and locally–led management of antimicrobial resistance (AMR) and Neglected Tropical Diseases (NTDs), Africa One Health Network for Disease Prevention (ADAPT), Project Launch, College of Health Sciences (CHS) and the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Monday 12th May 2024, Protea Hotel, Entebbe, Uganda, East Africa.
Some of the participants at the kick-off event.

The kickoff meeting was addressed by stakeholders from different sectors who made proposals aimed at ensuring a successful project implementation. Hon. Dr. Charles Ayume, the Chair of the parliamentary health committee, while addressing the forum urged the implementers to consider involving the political wings of the respective countries and to ensure that the politicians get to appreciate the concerns on Anti-Microbial Resistance and the Neglected Tropical Diseases.   He said that in the case of Uganda, the process of the formation of the Parliamentary Forum on AMR was in the initial stages and observed that several politicians were not well informed about the challenges of AMR.  He said bringing the politicians on board would help the project implementers and stakeholders lobby for financial allocations towards AMR or else refer to it as unfunded priorities because they do not appreciate its magnitude. Dr. Ayume regretted noting that although innovations were game changers, Research and development were underfunded and mostly anchored in the hands of the donors.  He said regarding the success of the project, research was important because of the need to domesticate AMR, by taking it down lower to the communities.

Hon. Dr. Charles Ayume, the Chair of the Parliamentary health committee, addressed the meeting. Seated are Prof. Damalie Nakanjako and Assoc. Prof. Julius Okuni. Consortium of Seven Sub-Saharan countries; Senegal, Ghana, Nigeria, the Democratic Republic of the Congo, Ethiopia, Sudan and Uganda, Leipzig University Germany, 5-year intervention aimed at building the capacity of improved, sustainable, and locally–led management of antimicrobial resistance (AMR) and Neglected Tropical Diseases (NTDs), Africa One Health Network for Disease Prevention (ADAPT), Project Launch, College of Health Sciences (CHS) and the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Monday 12th May 2024, Protea Hotel, Entebbe, Uganda, East Africa.
Hon. Dr. Charles Ayume, the Chair of the Parliamentary health committee, addressed the meeting. Seated are Prof. Damalie Nakanjako and Assoc. Prof. Julius Okuni.

Dr. Ayume said he was cognizant of the fact that there was a lot to do citing the example of the poor state of abattoirs regarding lack of adherence to public health regulations, poor sanitation as well and non-adherence to public health regulations. Legislation is important because several laws like the Public Health Act although amended do not cover AMR, he observed. He cited the recently enacted Animal Feeds Bill, as one example through which the Government can be held accountable.  He expressed commitment to further spread the AMR message through the Parliamentary Committees of Health from Africa, where he is a member.  For most of the issues that affect the region, he said there was a need to get together, and that this can be a way of domestication of AMR.

The Deputy Principal, CoVAB, Assoc. Prof James Acai–Okwee welcomed the guests. Consortium of Seven Sub-Saharan countries; Senegal, Ghana, Nigeria, the Democratic Republic of the Congo, Ethiopia, Sudan and Uganda, Leipzig University Germany, 5-year intervention aimed at building the capacity of improved, sustainable, and locally–led management of antimicrobial resistance (AMR) and Neglected Tropical Diseases (NTDs), Africa One Health Network for Disease Prevention (ADAPT), Project Launch, College of Health Sciences (CHS) and the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Monday 12th May 2024, Protea Hotel, Entebbe, Uganda, East Africa.
The Deputy Principal, CoVAB, Assoc. Prof. James Acai–Okwee welcomed the guests.

The Deputy Principal, CoVAB, Prof James Acai – Okwee who spoke on behalf of the Principal Prof. Frank Nobert Mwiine acknowledged and welcomed the partners from other countries and the German Federal Ministry of Education for the project support. He said Makerere University aspires to translate into a research-led institution including research in AMR.  He explained that there was a significant animal factor in AMR, where infection in animals will always be shared in the human population because of the extensive microbial use in animal production.  Anti-microbial use is becoming the normal practice in production and therefore 75% of the infections originate from the animals that’s why we appreciate the one health approach in addressing AMR, the environment, food production, and public health he said, while appreciating the need for a multi-sectoral approach in addressing the challenge at hand. He expressed the colleges’ commitment and readiness to work with the project team led by Assoc. Prof. Julius Okuni.

Other presenters at the meeting included a representative of the Director General of Health Services, the Ministry of Health, and the Ministry of Water and Environment, among others.

The Team visiting the labs at CEBIGH at CoVAB. Consortium of Seven Sub-Saharan countries; Senegal, Ghana, Nigeria, the Democratic Republic of the Congo, Ethiopia, Sudan and Uganda, Leipzig University Germany, 5-year intervention aimed at building the capacity of improved, sustainable, and locally–led management of antimicrobial resistance (AMR) and Neglected Tropical Diseases (NTDs), Africa One Health Network for Disease Prevention (ADAPT), Project Launch, College of Health Sciences (CHS) and the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Visit to CEBIGH, 15th May 2024, Makerere University, Kampala Uganda, East Africa.
The Team visiting the labs at CEBIGH at CoVAB.

Later on Wednesday 15th May 2024, the project team visited the College of Veterinary Medicine, Animal Resources, and Biosecurity where they interacted with the leadership and staff and took a guided tour of some of the laboratories.

Harriet Musinguzi

Health

Call For Applications: Masters Support In Self-Management Intervention for Reducing Epilepsy Burden

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An elevated shot of the School of Health Sciences and School of Medicine Building, College of Health Sciences (CHS), Makerere University. Mulago Campus, Kampala Uganda, East Africa.

Self-management Intervention for Reducing Epilepsy Burden Among Adult Ugandans with Epilepsy: Grant Number: R01NS129041.

CALL FOR APPLICATIONS FOR MASTERS SUPPORT IN SELF-MANAGEMENT INTERVENTION FOR REDUCING EPILEPSY BURDEN.

The Makerere University College of Health Sciences and Case Western Reserve University, partnering with Mbarara University of Science and Technology, are implementing a five-year project titled “Self-management Intervention for Reducing Epilepsy Burden Among Adult Ugandans with Epilepsy.”

The program is funded by the National Institute of Health (NIH) and the National Institute of Neurological Disorders and Stroke (NINDS). One aspect of the program is to provide advanced degree training to qualified candidates interested in pursuing clinical and research careers in Epilepsy. We are aiming to grow epilepsy research capacity, including self-management approaches in SSA.

The Project is soliciting applications for Masters Research thesis support focusing on epilepsy-related research at Makerere University and Mbarara University, cohort 2, 2025/2026.

Selection criteria

  • Should be a Masters’ student of the following courses; MMED in Internal Medicine, Paediatrics, Surgery and Neurosurgery, Psychiatry, Family Medicine, Public Health, Master of Health Services Research, MSc. Clinical Epidemiology and Biostatistics, Nursing or Masters in the Basic Sciences (Physiology, Anatomy, Biochemistry, or any other related field).
  • Should have completed at least one year of their Masters’ training in the courses listed above.
  • Demonstrated interest in Epilepsy and Neurological diseases, care and prevention, and commitment to develop and maintain a productive career and devoted to Epilepsy, Clinical Practice, and Prevention.

Research Programs:

The following are the broad Epilepsy research priority areas (THEMES) and applicants are encouraged to develop research concepts in the areas of; Applicants are not limited to these themes; they can propose other areas.

  • The epidemiology of Epilepsy and associated risk factors.
  • Determining the factors affecting the quality of life, risk factors and outcomes (mortality, morbidity) for Epilepsy, epilepsy genetics, and preventive measures among adults.
  • Epilepsy in childhood and its associated factors, preventative measures etc.
  • Epilepsy epidemiology and other Epilepsy related topics.
  • Epilepsy interventions and rehabilitation

In addition to a formal masters’ program, trainees will receive training in bio-ethics, Good Clinical Practice, behavioral sciences research, data and statistical analysis and research management.

The review criteria for applicants will be as follows:

  • Relevance to program objectives
  • Quality of research and research project approach
  • Feasibility of study
  • Mentors and mentoring plan; in your mentoring plan, please include who are the mentors, what training they will provide and how often they propose to meet with the candidate.
  • Ethics and human subjects’ protection.

Application Process

Applicants should submit an application letter accompanied with detailed curriculum vitae, two recommendation letters from Professional referees or mentors and a 2-page concept or an approved full proposal describing your project and addressing Self-Management Intervention for Reducing Epilepsy Burden Among Adult or epilepsy related problem.

A soft copy should be submitted to the Administrator, Reducing Epilepsy Burden Project.  Email: smireb2@gmail.com; Closing date for the Receipt of applications is 1st July 2025.

For more information, inquiries and additional advice on developing concepts, please contact the following:

Makerere University College of Health Sciences

Prof. Mark Kaddumukasa:  kaddumark@yahoo.co.uk

Mbarara University

Ms. Josephine N Najjuma: najjumajosephine@yahoo.co.uk

Only short-listed candidates will be contacted for Interviews.

Mak Editor

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MakSPH METS 2024 Annual Report

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Cover image of the MakSPH METS 2024 Annual Report featuring The U.S. Ambassador to Uganda, H.E. William W. Popp, Minister of Health, Hon. Dr. Jane Ruth Aceng and other officials. Photo: METS. Makerere University School of Public Health (MakSPH), Monitoring and Evaluation Technical Support (METS) Program, Kampala Uganda, East Africa.

I am pleased to present our annual report. Throughout the past year, MakSPH-METS Program has remained steadfast in its mission to strengthen Uganda’s capacity for HIV and TB programming through strengthening robust health information systems, surveillance, and quality improvement initiatives.

MakSPH leverages its team of expertise in public health to guide program strategies, strengthen national capacity for data collection, analysis, and use. The innovations developed are solutions for health system challenges and they generate evidence that can be used to inform policy and practice.

MakSPH-METS provides technical support to MoH, RRHs, implementing partners at different health system levels.

Our collaborative approach, working closely with the Government of Uganda and various stakeholders, has enabled us to make significant strides in building sustainable health information systems and improvingthe quality of healthcare delivery. The achievements highlighted in this report reflect our commitment to strengthen health systems through development and implementation of innovative and impactful evidence- based solutions.

As we look to the future, I am confident that the METS Program will continue to play a pivotal role in strengthening Uganda’s health systems through several initiatives.

  1. Operationalising a sustainability plan through transitioning of the developed innovations to the Ministry of Health for ownership.
  2. Disease outbreak management will be strengthened through continued capacity building for emergency response and optimization of existing integrated disease surveillance systems. The field teams will facilitate seamless coordination across health system levels to build sustainable and resilient health systems capable of effectively responding to public health emergencies.
  3. Lastly, we continue to strengthen collaboration with government, enhance coordination with implementing partners and promoting integration of health services.

Our dedicated team of professionals, combined with the unwavering support from our partners and stakeholders, positions us well to address emerging health challenges and advance our nation’s public health goals. The innovative solutions and capacity-building initiatives highlighted in this report demonstrate not only our progress but also our potential for greater impact in the years ahead.

Professor Rhoda Wanyenze
Dean – School of Publc Health, Makerere University

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KeyScope Project Job Advert: Junior Research Fellow

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Part of the team at the Makerere University Biomedical Engineering Unit under the Department of Physiology, College of Health Sciences (CHS), Kampala Uganda, East Africa.

Background

Makerere University Biomedical Engineering Unit under the Department of Physiology is glad to advertise for positions under its new Project ‘KeyScope Project: The Key to Sustainable Cancer Diagnosis and Treatment in Uganda.”

Laparoscopic surgery is considered as the standard of care for cancer treatment in high-income countries. However, this technology is rarely accessible to LMICs due to the high cost of installment, lack of maintenance personnel, unreliable electricity, and shortage of consumable supplies. To address these concerns, a unique multidisciplinary collaboration between engineers, surgeons, oncologists, and business experts from Duke University, Makerere University, Uganda Cancer Institute and University of Maryland joined efforts to develop a low-cost, durable laparoscopic system (KeySuite) for use in resource- constrained environments.

Our aims are aligned to demonstrating the local capacity to manufacture, acquire local and international regulatory approval, determine clinical performance and distribute/sell the KeyScope to the local market. Specifically, we shall improve the current design and determine the local capacity to manufacture the device, establish the clinical safety and acceptability of the product, and obtain regulatory approval from local and international accredited bodies.

Position: Junior Research Fellow

Reports to: Project Coordinator

Engagement: Full time

Duration: 1 year renewable upon satisfactory performance

Duty Station: Kampala

Roles and responsibilities

As a trainee, a Junior Research Fellow will closely work with a research team to undergo training design, manufacturing and validation of the KeyScope. This is a non-degree/no-credit training opportunity that will prepare the successful candidate for advanced studies and future industry work in an upcoming medical technology sector of Uganda and Africa at large.

Specifically the Fellow will;

  1. Participate in the local construction of the KeyScope through material assessment and selection, developing a product manufacturing plan, and carrying out an impact assessment.
  2. Aid in the establishment of clinical safety and acceptability of the KeyScope through the use of a feasibility study to secure approvals, recruit patients and surgeons.
  3. Contribute to the process of attaining regulatory approval from a certified body for the KeyScope.
  4. Contribute to the development of a commercialization plan under training and mentorship of a Business Developer.
  5. Actively engage in project documentation, questionnaire and ethics protocol development, journal article writing and publication, report writing.
  6. Conduct key informant interviews, administer questionnaires, and verbatim transcription of interview recordings.
  7. Participate in data collection and analysis using digital and paper-based tools.
  8. Participate and contribute to teaching and student mentorship.
  9. Engage with the research partners and stakeholders.
  10. Any other activities as assigned by the Principal Investigator, and Project Coordinator (Immediate Supervisor) from time to time.

Qualifications:

  1. Completed a Bachelor’s Degree in Biomedical Engineering or any closely related field and at least awaiting graduation in not more than 6 months from an accredited University in Uganda.
  2. If completed, candidate must not have graduated more than 1 year ago.
  3. Academic qualifications of having attained or expecting at least expecting a second-class upper division degree.
  4. Experience in Human-Centered Design skills and Design Thinking will be highly considered.
  5. Prior experience in working with international multidisciplinary teams and organizations.
  6. Experience of previous work on laparoscopy is a plus.
  7. Evidence of prior interest for research, design, innovation and medical device manufacturing.
  8. Applicant should have a desire to work with different fabrication techniques.
  9. Ability to multitask and perform duties in learning environment with minimum supervision
  10. Excellent scientific writing skills and a good command of communication skills.

How to Apply:

All suitably qualified and interested candidates should submit a one-page cover letter, one-page writing sample, CV (maximum 3 pages) with relevant certificates, transcripts & two reference letters as a single digitally signed PDF file addressed to the Project PI and emailed to keyscopeu01@gmail.com by 17:00hours on 18th April 2025. Indicate, “KeyScope Project” in the subject line. Those awaiting graduation should send their most recent testimonials. Only shortlisted applicants will be contacted.

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