The Minister of Health, Hon. Dr. Jane Ruth Aceng (2nd R) visiting the METS stall manned by Jaba Jeremiah (L) and Musa Mwanje (blue polo shirt) at the First National Digital Health Conference held 13th - 14th November 2023. Photo: METS.
The Monitoring and Evaluation Technical Support (METS) Program is a 5-year CDC-supported collaboration of Makerere UniversitySchool of Public Health (MakSPH), the University of California San Francisco (UCSF) and Health Information Systems Program (HISP Uganda).
Highlights of the METS November 2023 Newsletter
Strengthening Regional Referral Health Systems: A Year of Progress
In 2021, MakSPH-METS in collaboration with MoH designed a Monitoring and Evaluation (M&E) framework based on the World Health Organization’s (WHO) Health System building blocks was developed. This framework employs a Progression Model to measure improvements in health systems capacity.
The framework was piloted at the RRH in 2022 to obtain a baseline on the existing health capacities at the hospitals. A follow-on assessment was conducted in 2023 to measure if there were improvements in the health systems capacities. Overall, significant improvements were observed across the six health system building blocks: Governance and Leadership; Medicines, Health Supplies, Vaccines and Equipment; Health Information System and Integrated Disease Surveillance & Response; Human Resource
for Health; Health financing; and Service delivery.
Welcoming new Implementing Mechanisms (IMs)
METS, the lead Strategic Information (SI) mechanism, in collaboration with CDC, organized an orientation workshop to support new implementing mechanisms as they transition to take on work load in the various regions in Uganda.
The new mechanisms are Trust AIC Foundation supporting Soroti Region, Reach Out Mbuya Community Health Initiatives in Kampala Region. METS will continue supporting the new mechanisms to ensure compliance with national and PEPFAR requirements.
Unlocking Scientific Excellence Through Collaborative Learning
The METS program and CDC Uganda’s Office of Science collaborated on a five-day writing workshop aimed at synthesizing program results and advancing the development of scientific papers for publication.
Key focus areas included reporting methods, analytic approaches, manuscript writing best practices, and regulatory protocols. Moving forward, the plan involves sustaining momentum by engaging program teams, utilizing regular touch-base sessions with CDC Office of Science and Subject Matter Experts to ensure quality and coherence in scientific content.
Enhancing Client-Centered Care through use of Innovative Tools
In a concerted effort to revolutionize client centered care, the Ministry of Health (MoH), working closely with MakSPH-METS and USAID – Uganda Health Activity (UHA), introduced an audit tool, embedded within the national quality improvement collaboratives.
A one-day national Training of Trainers (ToT) was organized to not only enhance client-centered care but also empower regional teams as Trainers for the widespread implementation of this tool.
Gallery
The scientific writing workshop
The Union World Conference on Lung Health 2023
Workshop on Leveraging the HIV platform for Hypertension control in Uganda
Lauch of National Global Alliance campaign aimed at eliminating AIDS in children by 2030
South African Health Informatics Association Conference 2023
The Sanger Prize presents a wonderful opportunity for genomics students in low and middle income countries, therefore the prize administrators are keen for the application information to reach as many eligible people as possible.
A Voice for Excellence, Equity and African Sovereignty
When Dr. Michael Makanga walked onto the stage at the 8th Galien Forum Africa in Dakar on 31 October 2025 to receive the Special Career Achievement Galien Prize, presented by President Bassirou Diomaye Faye under the theme Health sovereignty: an imperative for Africa, the moment carried weight beyond any medal or citation. “It is a celebration of a lifelong commitment,” he said, “but also a reminder of a responsibility I have never been willing to compromise: to inspire others to raise their voices for excellence, science, and equity.”
For more than two decades, Dr. Makanga has been a quiet architect of Africa’s health sovereignty. His work has unfolded far from cameras: in laboratories constrained by resources, in policy rooms where African priorities demanded a stronger voice, and in mentoring sessions with young scientists seeking reassurance that their ideas mattered.
Born and trained in Uganda, Dr. Makanga earned a Bachelor of Medicine and Surgery from Makerere University before pursuing a master’s degree and PhD at the Liverpool School of Tropical Medicine. His career spans nearly 30 years, encompassing tropical medicine, clinical trials in Africa and Europe, and senior international management roles. Since joining EDCTP in 2004, he has guided its growth as a unique Africa–Europe partnership, strengthening African capacity for high-quality, ethical clinical research while accelerating solutions for poverty-related diseases. Today, he leads the Global Health EDCTP3 Joint Undertaking under the EU’s Horizon Europe programme.
President Faye captured the essence of Dr. Makanga’s achievement: “Scientific excellence is not negotiable; it is earned. It underpins our credibility and our sovereignty.” For Dr. Makanga, the statement is a call to action. “I hope this recognition reminds us that Africa’s scientists and innovators can lead global health research with excellence and purpose. We owe it to the next generation to build the systems and confidence that make this possible,” he said.
Dr. Makanga’s peers describe him as a “builder”: someone who strengthens research systems, mentors emerging scientists, and fosters equitable partnerships long before “local ownership” became a policy buzzword. In his own words, the award honors his “career’s contribution to advancing Africa’s health sovereignty” while reinforcing his commitment to ensure younger scientists do not have to fight for legitimacy as previous generations did.
The 2025 Prix Galien Africa celebrated Dr. Makanga alongside innovators reshaping African science. La Ruche Health, a Côte d’Ivoire-based digital health platform, won for connecting users to certified providers through an AI-powered system. Senegalese computer scientist Adji Bousso Dieng received a special prize for applying artificial intelligence to the natural sciences, including spotting emerging viral variants using her “Vendi Score” tool. The awards were organised with the support of the Presidency of Senegal, the Gates Foundation, the West African Health Organization, and the Rockefeller Foundation, with a jury co-chaired by Dr. John Nkengasong and Professor Souleymane Mboup.
Yet the award’s true weight lies not in ceremony, but in its symbolism. Dr. Makanga’s career exemplifies how African scientists can lead, shape policy, and influence global health priorities when empowered and supported.
L-R: La Ruche Health (Côte d’Ivoire) innovator, President of Senegal, Bassirou Diomaye Faye, Dr Michael Makanga (Uganda) and Adji Bousso Dieng (Senegal)
Makerere University colleagues attest to this impact. Dr. Victoria Nankabirwa, a clinical researcher and epidemiologist, reflects: “EDCTP support allowed me to build multidisciplinary teams, enhance laboratory and trial infrastructure, and generate evidence relevant for policy and practice. It strengthened my scientific independence and expanded the long-term sustainability of my research, particularly on childhood vaccines.”
She adds, “Dr. Makanga’s vision and commitment have strengthened institutions, built capacity, and fostered equitable partnerships, enabling African investigators to lead complex studies that address the continent’s priorities. His recognition shows what is possible when scientists are empowered, trusted, and supported.”
Dr. Alex Kayongo, an immunologist at Makerere University, describes EDCTP support as “catalytic,” enabling advanced training and a platform to study microbiome–immune interactions in HIV-associated COPD. His work is shaping mechanistic insights and strengthening Uganda’s capacity for complex respiratory immunology research. “Global health funding is increasingly competitive, making EDCTP’s role even more vital,” he says. “Africa needs sustainable support for complex, lab-intensive research. Continued investment in infrastructure, leadership, and fair partnerships is essential if African institutions are to drive innovation and secure true scientific sovereignty.”
Dr. David Musoke, an associate professor of disease control, credits his EDCTP fellowship with deepening his malaria research and advancing his career. His studies combined housing improvements, environmental management, and behavioural measures to complement traditional malaria prevention, shaping practical, community-informed interventions. “Dr. Makanga’s contribution to African science has been tremendous, and his continued stewardship gives us confidence that evidence generated on the continent will increasingly shape policy and practice,” he observes.
Dr. Makanga’s impact is visible not only in individual careers but across institutions and nations. Through EDCTP, he has championed African-led trials, strengthened laboratory capacity, and fostered cross-country collaboration. Colleagues emphasize that his leadership has created a generation of African scientists who are confident, collaborative, and globally competitive.
“My experience with EDCTP-funded programmes has shown the transformative impact of African-led research,” Dr. Nankabirwa reflects. “Dr. Makanga’s vision and commitment have strengthened institutions, built capacity, and fostered equitable partnerships, enabling African investigators to lead complex studies that address the continent’s priorities. His recognition shows what is possible when scientists are empowered, trusted, and supported, inspiring the next generation of research leaders.”
Dr. Makanga’s recognition is a tribute to perseverance, vision, and mentorship: a scientist who kept going when resources were scarce, a leader who refused partnerships that treated Africans as subjects, and a mentor who reminded young researchers that they belong at the centre of global science.
As he stood among Africa’s leading innovators in Dakar, the message was unmistakable: Africa can lead, Africa must lead, and it will lead, through science, excellence, and equity.
Makerere University is proud to celebrate Dr. Michael Makanga, one of its distinguished alumni, on receiving the Special Career Achievement Prize of the Prix Galien Africa 2025. This honor recognises his exceptional leadership in medical research and his role in advancing African-led science. Through his work, Dr. Makanga continues to strengthen institutions, mentor emerging researchers, and amplify Africa’s voice on the global health stage.
Kalangala, an idyllic archipelago often romanticised for its sunsets, today witnessed a historic leap in healthcare. Makerere University Vice Chancellor, Prof. Barnabas Nawangwe, launched the Infectious Diseases Institute (IDI) Kalangala Clinical Research Centre—the island’s first modern research facility.
“This is more than a building; it’s a lifeline,” said Prof. Nawangwe. “IDI is not only Uganda’s leading health partner, managing over 20% of HIV cases, but research is first on its agenda. If people are not healthy, they can’t work—it’s useless to invest in anything else.”
Prof. Nawangwe unveils the Kalangala Facility plaque.
Kalangala ranks third in HIV prevalence nationwide at 13.1%, with fishing communities hardest hit. Until now, residents endured perilous boat rides to the mainland for advanced care. “Accessing healthcare has always meant a journey across waves—long, costly, and sometimes dangerous,” said District Chairperson Jajab Ssemakula. “You have not only invested in Kalangala; you have brought Makerere University to Kalangala.”
Supported by the Gates Foundation, the centre is part of a multinational HIV prevention study conducted across 31 sites in Kenya, South Africa, and Uganda. Its first mission: testing whether a monthly pill can protect adolescent girls and young women from HIV—a breakthrough that could transform vulnerable communities.
Prof. Barnabas Nawangwe addresses guests.
“This centre means access without barriers,” said Dr. Andrew Kambugu, IDI Executive Director. “Kalangala residents no longer need to travel long distances for clinical trials or advanced care.”
Dr. Andrew Kambugu.
Prof. Samuel Luboga, IDI Board Chairperson, reassured residents of IDI’s long-term commitment: “We are not a fleeting partner. This sentinel research centre aligns with our vision of freeing Africa from the burden of infectious diseases. The assurance I give Kalangala is—we are here to stay.”
Officials pose for a group photo shortly after the facility’s launch.
Henry Ssebunya, Deputy Resident District Commissioner, praised IDI’s innovation and consistency: “IDI has treated and cared for people living with HIV, deployed medical drones to deliver life-saving medicines, and now built a research centre. This is a new chapter for Kalangala.”
Prof. Nawangwe and other officials receive a guided tour of the facility.
From a sleeping sickness camp in 1906 to a cutting-edge research hub in 2025, Kalangala’s story is one of resilience, innovation, and hope.
“Makerere University Infectious Diseases Institute (IDI) Kalangala Clinical Research Centre, Officially inaugurated on 20th November 2025 by Prof. Barnabas Nawangwe, Vice Chancellor, Makerere University with funding from Gates Foundation.”