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Veterinary & Biosecurity

Stakeholders to take on Electronic Rabies Surveillance using a One Health Approach in the control of Rabies

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Stakeholders in the Rabies Elimination project in Uganda (eRabies) have intensified efforts aimed at the use of electronic Rabies Surveillance using a One Health approach in the efforts towards elimination of rabies in Uganda.

A two-day workshop was convened at the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University from 28th-29th August 2023, during which the stakeholders deliberated on a number of proposals for the best applicable surveillance tools to address One Health concerns in the effort towards the elimination of Rabies.

Prof. Clovice Kankya, Head of Department, Biosecurity, Ecosystems and Veterinary Public Health at CoVAB. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Prof. Clovice Kankya, Head of Department, Biosecurity, Ecosystems and Veterinary Public Health at CoVAB.

‘The purpose of the meeting is to hear from various actors and see what works for us, to enable us collect information and have it shared in a sustained way with One Health as a key component’ said Prof. Clovice Kankya, the Head, Department of Biosecurity, Ecosystems and Veterinary Public Health at CoVAB, at the start of the meeting held in the Centre for Biosecurity and Global Health.

Kankya noted that with one year of implementation to date, the eRabies project was progressing well drawing a lot of support from the implementing local Governments of Kyegegwa, Soroti and Kampala Capital City Authority that spearhead the community engagements and other related activities. He said the graduate fellows from the Ministry of Health and Ministry of Agriculture, Animal Industry and Fisheries supported by the project were also on schedule.

He said Rabies is a global challenge being a zoonotic disease affecting the entire world more so here in Africa where there is close interaction between the wild animals and the human population.  The Uganda Wildlife Authority, he said, was brought on board specifically Queen Elizabeth National Park to address some of the challenges affecting people drawing from the wild animals.

Prof. James Acai-Okwee, Deputy Principal CoVAB officiated at the opening. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Prof. James Acai-Okwee, Deputy Principal CoVAB officiated at the opening.

The Deputy Principal CoVAB, Prof. James Acai Okwee, in his opening remarks noted through the eRabies project, Makerere University and the host CoVAB were consolidating efforts towards the control of rabies in Uganda. ‘In as much as Rabies is a killer 100%, it is also preventable 100%’ observed Prof. Acai, adding that Makerere University and CoVAB specifically have been involved in such efforts through filed activities, vaccinations and animal welfare programs aimed at the control of rabies.  He said through research, such efforts were to be intensified from a scientifically informed point of view.

Prof. Sonja Hartnack, from the Vetsuisse Faculty, University of Zurich gives the background to the project. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Prof. Sonja Hartnack, from the Vetsuisse Faculty, University of Zurich gives the background to the project.

Prof. Sonja Hartnack, from the Vetsuisse Faculty, University of Zurich, one of the partners gave an overview of the project.  She said the four-year project has seven different work packages while emphasizing that presently, the stakeholders were addressing work package one, that entails Surveillance systems and integrated bite case management.  She noted that the communities were crucial in the rabies control efforts and specifically in identifying the barriers for rabies control through research interventions and the development of educational materials for awareness creation.

She made reference to the World organization for Animal Health (WOAH) recommended practices that points out that dog owners are clearly identified as one way through which the barriers to dog vaccination can be addressed in the communities and emphasized responsible dog ownership.

Participants engage in group work. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Participants engage in group work.

She said it was important to assess which vaccinations approaches are most successful in terms of vaccination coverage, whether there were static points vaccinations, or linked to institutions like Schools or other Veterinary activities or even human health related activities. She said through quantitative and qualitative research, the eRabies project was set to establish what works.  She also pointed out the need to increase the laboratory capacity at regional levels as well as taking on rapid tests in the field.

Prof. Sonja Hartnack said the deliberations in the meeting were to inform the efforts towards having an integrated bite case management (IBCM) system by looking at different systems, picking out key data elements, reviewing the challenges of the existing processes for a proper One Health approach.

Dr.  Andrew Kambugu, Director, Infectious Disease Institute (IDI) affirms IDI’s support to the project. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Dr. Andrew Kambugu, Director, Infectious Disease Institute (IDI) affirms IDI’s support to the project.

Dr.  Andrew Kambugu, Director, Infectious Disease Institute (IDI) one of the key partners in the eRabies project extended appreciation to the Swiss Government and the Swiss National Science Foundation (SNSF) for the grant that is supporting the implementation of the activities.  He referred to COVID-19, a Zoonotic disease that affected many people as having come from the contact between animals and humans.  He said the model that would come out of the meeting was to be relevant to many.  He emphasized the need for increased collaboration between different agencies in Africa, where he noted that many were working in silos.  He affirmed that IDI was to give all relevant support needed in the eRabies project.

The deliberations in the workshop shared experiences from varied stakeholders that included the Infectious Diseases Institute experiences of Rabies Surveillance in West Nile region, the respective implementing Local Governments, Ministry of Health and Ministry of Agriculture Animal Industry and Fisheries.

Group work presentations by participants. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Group work presentations by participants.

Participants identified some of the challenges experienced in timely dog bites reporting that need to be addressed in the surveillance.  They included late reporting by the victims, failure to capture data from the private Veterinary Medicine practitioners that handle a number of cases in the communities, omission of the wildlife Veterinarians in the reporting system and the little interaction between the Human Health practitioners and the Veterinarians, coupled with the limited data sharing avenues.

Participants in a plenary session. Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda. East Africa.
Participants in a plenary session.

The eRabies project is implemented by Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Infectious Diseases Institute (IDI) in collaboration with the Vetsuisse Faculties, Universities of Bern and Zurich from Switzerland. It is contributing to efforts towards elimination of Rabies by 2030.

Veterinary & Biosecurity

Makerere University Anti-Tick Vaccine Project Committee Visits Production Site in Namanve

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Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Waikiso Uganda, East Africa.

The Makerere University Anti-Tick Vaccine Project Committee visited Alfasan Uganda Ltd on 24th June 2024 to review the advancements in the Anti-tick vaccine project, particularly focusing on the progress in the establishment of the vaccine production line at Alfasan Uganda Limited. This visit signifies a significant milestone in the ongoing partnership between Makerere University and Alfasan, as they work together towards the creation of a successful Anti-Tick vaccine.

The Principal Investigator (PI) of the Anti-Tick Vaccine Project, Dr. Margaret Saimo-Kahwa welcomed the team and gave a brief overview of the project’s operations. She highlighted Alfasan’s expertise in manufacturing veterinary and human drugs and the suggestion by H.E, the President of Uganda gave in view of the collaboration between Alfasan and Makerere University for the production of the Anti-Tick vaccine. The PI assured team that Alfasan was fully equipped to develop the vaccine in  adherence with the standards set by the National Drug Authority.

Dr. Margaret Saimo-Kahwa, PI of the Anti-Tick Vaccine showing the Committee some of the verification equipment at Alfasan. Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Wakiso Uganda, East Africa.
Dr. Margaret Saimo-Kahwa, PI of the Anti-Tick Vaccine showing the Committee some of the verification equipment at Alfasan.

The Managing Director of Alfasan, Dr. Stephen Birungi said he was delighted to work with Makerere University, where he once studied at the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB). He said a successful collaboration was key in ensuring further advancements and innovations in the field of veterinary medicine.

The Chairperson of Makerere University’s Anti-Tick Vaccine Project Steering Committee, Prof. Henry Alinaitwe emphasized the national significance of the project, and that it was catered for in the national budget. He outlined the division of equipment between Makerere University and Alfasan, stressing the importance of the visit to assess the progress at the Anti-Tick Vaccine production site in Namanve.

The Chairperson of Makerere University Anti-Tick Vaccine Project Committee, who is also the Acting Deputy Vice-Chancellor, Finance and Administration, Prof. Henry Alinaitwe, together with the CoVAB Principal Prof. Frank Norbert Mwiine took a guided tour around the Vaccine Production Facility. Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Wakiso Uganda, East Africa.
The Chairperson of Makerere University Anti-Tick Vaccine Project Committee, who is also the Acting Deputy Vice-Chancellor, Finance and Administration, Prof. Henry Alinaitwe, together with the CoVAB Principal Prof. Frank Norbert Mwiine took a guided tour around the Vaccine Production Facility.

The facility Pharmacist at Alfasan, Mr. Ivan Kafeero provided a brief history of the company, highlighting its transformation from an international collaboration to a prominent private entity in Uganda. The collaboration between Alfasan and Makerere University resulted in the joint production of a laboratory experimental vaccine in 2022, necessitating the facility’s upgrade to accommodate vaccine production alongside pharmaceuticals.

During the tour of the vaccine production facility led by Mr. Kafeero, various departments were showcased, including raw material warehouses, production sections, laboratories, and packaging rooms. The comprehensive tour demonstrated the facility’s readiness for vaccine production and emphasized the critical need for sustainable energy and water sources to support the operations effectively.

The Project Committee and the Project team during the guided tour around the vaccine manufacturing facility led by the facility Pharmacist, Mr. Ivan Kafeero. Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Wakiso Uganda, East Africa.
The Project Committee and the Project team during the guided tour around the vaccine manufacturing facility led by the facility Pharmacist, Mr. Ivan Kafeero.
The Project Committee and the Project team during the guided tour around the vaccine manufacturing facility led by the facility Pharmacist, Mr. Ivan Kafeero. Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Wakiso Uganda, East Africa.
The Project Committee and the Project team during the guided tour around the vaccine manufacturing facility led by the facility Pharmacist, Mr. Ivan Kafeero.

Following discussions and observations during the visit, the Committee Chairperson commended the progress achieved thus far and confirmed plans for a follow-up visit in two months to monitor the facility’s operational readiness for commencing production.

The collaborative partnership between Makerere University and Alfasan signifies a ground-breaking initiative in animal healthcare research and underscores the potential for significant advancements in combating tick-borne diseases through innovative collaborations and dedicated efforts.

The meeting between Makerere University Anti-Tick Vaccine Project Committee, the Anti-Tick Vaccine Project team, and the Team from Alfasan on 24th June 2024. Makerere University Anti-Tick Vaccine Project Committee visit to Alfasan Uganda Ltd on 24th June 2024, Namanve, Wakiso Uganda, East Africa.
The meeting between Makerere University Anti-Tick Vaccine Project Committee, the Anti-Tick Vaccine Project team, and the Team from Alfasan on 24th June 2024.

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Veterinary & Biosecurity

CoVAB Annual Report 2023

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The Principal CoVAB, Prof. Frank Norbert Mwiine. College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, Kampala Uganda, East Africa.

It is my pleasure to share the Annual Report for the year 2023, which highlights various milestones realized in the College of Veterinary Medicine, Animal Resources, and Biosecurity. First and foremost, I wish to congratulate all of us for the input rendered in the running of the college during the period, which effort made us score in several areas as prescribed by the mandate of the college and Makerere University as a whole.

Our mandate is teaching and learning, research and innovation, as well as knowledge transfer and partnerships. As you will realize in this report, this task has been handled meticulously through a concerted effort by all stakeholders, the students, the teaching, and the administrative staff and partners. The college takes pride in the contribution made by our partners who continue to support us in the delivery of the mandate in varied ways, such as Norbrook (U) Ltd, which since 2021 has continued to prize the best performing Veterinary students with cash prizes every year.

The College continues to excel in research and community outreach as evidenced by the increased research output in several Biomedical and Applied research projects with support from the Government of Uganda and our development partners which for instance resulted in the establishment of a Biomarker discovery and translation research laboratory at COVAB. Equipment was procured to support the development of point-of-care diagnostic kits for infectious and non-communicable diseases including cancer. The goal is to translate identified biomarkers into point-of-care diagnostics for both human and veterinary medicine. The platform supports drug target discovery and elucidation of drug action mechanisms.

The college hosts a Central Laboratory Animal Research Facility that support pre-clinical studies in animal models for vaccines, therapeutics and diagnostics, alongside refurbished laboratories at Biosafety Levels 2 and 3 (BSL2, BSL3), fitted with state-of-the-art equipment to execute cutting edge basic and applied research.

This and other efforts strategically place CoVAB and Makerere at large in a position to confront major animal and even human health challenges as significant proportions of emerging and reemerging infectious diseases are of animal origin (Zoonotic).

We are looking forward to an even more successful period ahead of us, and together definitely we shall achieve all we set out to do.

Prof. Frank Nobert Mwiine
PRINCIPAL

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Veterinary & Biosecurity

The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase at CoVAB

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Participants follow proceedings. The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase, June 20th, 2024, Ruth Keesling Centre, College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University, Kampala Uganda, East Africa.

The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase was held on June 20th, 2024, at the Ruth Keeslings Centre, College of Veterinary Medicine, Animal Resources, and Biosecurity, and for the first time involved CoVAB students.

The Boma was the final event of this year’s CoVAB-Mississippi State University’s (MSU) Tropical Veterinary Medicine and One Health Study Abroad program which started on May 31, 2024. The study abroad course focuses on animal production and health management, conservation medicine, aquatic health, wildlife health, public health, food safety, and security, as well as inculcating One Health principles while suffusing multicultural experiences.

During the presentations, the participants expressed what they enjoyed most while on the program and this included observing the human-wildlife interactions, working on wildlife and the identified difference between the US and Uganda, the animal welfare champion, as well as having Ugandan students included on the program.

Prof. Frank Nobert Mwiine, CoVAB Principal (C) Dr. Sarah Nalule, HoD WAAR (L) and Dr. David Kahwa Lecturer WAAR (R). The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase, June 20th, 2024, Ruth Keesling Centre, College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University, Kampala Uganda, East Africa.
Prof. Frank Nobert Mwiine, CoVAB Principal (C) Dr. Sarah Nalule, HoD WAAR (L) and Dr. David Kahwa Lecturer WAAR (R).

The Principal, Prof. Frank Nobert Mwiine officiated at the event characterized by sharing the student’s experiences through presentations made before academicians, researchers, and students.  In his remarks, he said the Boma was a great avenue for sharing information and learning from each other drawing from the experiences of the students while out in the community and the wild. Prof. Mwiine commended Mississippi State University for the long relationship they have had with CoVAB and appreciated the inclusion of the Uganda students into the program. He expressed optimism that the summer school will grow into problem-solving partnerships in research, training, and community development.

During the three weeks excursions in Uganda, participating students from Mississippi State University together with their counterparts from CoVAB engaged in experiential field trips with hands-on experience at the interfaces between animals, humans, and the environment.

The Team from Mississippi University appreciated CoVAB for the lead role in organizing the Summer School that brought the students into contact with new areas with most of them being in Africa for the first time.  He said the summer school was opening up opportunities for further collaboration in areas like student exchange programs as well as graduate research.  It was a great experience for the students to move out of their area to the unknown and the exposure left lifelong in print on the student’s academic, practice, and outlook towards life, said the representative of Prof. Stephen Reichley, the team leader.

Participants pose for a group picture in front of the Centre for Global Health, CoVAB. The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase, June 20th, 2024, Ruth Keesling Centre, College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University, Kampala Uganda, East Africa.
Participants pose for a group picture in front of the Centre for Global Health, CoVAB.

Dr. Celsus Sente the Summer School coordinator and lecturer in the Department of Wildlife and Aquatic Resources (WAAR) said the three-week expedition was a great field experiential learning opportunity using one health approach.  Students went to different places including Gaba Fish Landing Site, the Murchison conservation area, Mbarara Abattoir where they interacted with the meat inspectors, Kibaale conservation area where they observed wildlife practical activities like birds, undertook activities involving cattle, and goats as well as the feel of the interface between the environment, humans, and animal health, the one health approach at the fishing villages there.

A team makes a presentation at the Boma. The 2024 Summer School and the International Cultural Boma and AFROHUN Showcase, June 20th, 2024, Ruth Keesling Centre, College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University, Kampala Uganda, East Africa.
A team makes a presentation at the Boma.

The Boma as a concept in an African context means a meeting that allows learning and a two-way exchange of information between elders and youngsters. African culture involves the transfer of wisdom and knowledge from wise, knowledgeable, and highly experienced elders to the young who are mentored into responsible community members. The concept was therefore used to allow the opportunity to share knowledge from all stakeholders as experienced in the course of learning.

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