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Study Reveals Epilepsy Prevalence & Treatment Barriers in Uganda, Urgent Need for Awareness & Resources

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By Davidson Ndyabahika & Julius Mugaga Tukacungurwa

A new study conducted in Uganda has unveiled the prevalence of epilepsy and identified significant barriers to treatment. The study conducted by Makerere University School of Public Health in partnership with Ministry of Health and Duke Global Neurosurgery and neurology, utilized community-based screening methods, found that urgent action is needed to increase awareness and allocate more resources to address this pressing public health issue.

Nearly 80% of individuals with epilepsy reside in low- and middle-income countries (LMICs), and a staggering 75% of those with epilepsy in LMICs do not have access to treatment. This alarming trend is further exacerbated by the stigma surrounding epilepsy, which often leads people to avoid seeking medical care due to fear of discrimination or social ostracization. The study underscores the urgent need to address the barriers to treatment, including stigma, and allocate more resources to improve epilepsy care in LMICs.

By providing a community-based descriptive statement about epilepsy in Uganda, this study sought to contribute vital information for intervention planning, addressing the urgent need for increased awareness, support, and access to treatment for people living with epilepsy in Uganda.

At the Epilepsy National Prevalence Study Dissemination and Dialogue meeting held on Wednesday, April 5, 2023 at the Golden Tulip Hotel in Kampala, Professor Anthony Fuller, the USA & Duke Neurosurgery Principal Investigator, revealed concerning findings.

The study unveiled that the national prevalence rate of epilepsy in Uganda is alarmingly high at 1.69 per cent, indicating that over 770,000 Ugandans are living with the disease. Professor Fuller’s presentation shed light on the urgent need for increased awareness, support, and intervention for those affected by epilepsy in Uganda.

During the investigation, participants were asked about their experiences with epilepsy, including symptoms such as shaking, falling, loss of consciousness, bladder control, and abnormal sensations. These questions were part of the primary screen in Phase One of the study, aimed at gathering information on epilepsy-related experiences in the past year.

With a meticulous screening process, the study examined 35,056 individuals suspected to have epilepsy, of whom 2,284 were found positive for unadjusted epilepsy, translating to a prevalence rate of 6.52% in the primary phase.

In the secondary phase, 732 individuals were confirmed positive for unadjusted epilepsy, resulting in a prevalence rate of 2.09%. In this phase, participants were asked about the frequency of attacks, occurrence in children during fever, and association with malaria-related hospitalization. These questions sought to gather additional information to aid in assessing and analyzing the nature and context of participants’ experiences with epilepsy.

Through rigorous clinical validation, including Neuro validation and electroencephalogram (EEG) tests, 594 individuals were confirmed to have epilepsy, bringing the final prevalence rate to 1.69%.

In the Central region, out of 11,746 individuals screened, 198 were confirmed positive for epilepsy, while 11,548 were negative, resulting in a prevalence rate of 1.69%. In the Eastern region, 125 out of 5,776 screened were positive, with a prevalence rate of 2.16%. In the Northern region, 68 out of 5,037 screened were positive, resulting in a prevalence rate of 1.35%. Lastly, in the Western region, 203 out of 12,497 screened were positive, with a prevalence rate of 1.62%.

These regional findings shed light on the distribution of epilepsy cases in Uganda and highlight the need for tailored interventions and support at a local level. “The epilepsy prevalence is unevenly distributed, ranging from zero to over 5% in specific districts,” says study report.

Dr. Fredrick E Makumbi, an Associate Professor and a Ugandan Principal Investigator for the study from MakSPH, highlighted the gap in community awareness regarding epilepsy treatment, leading to an increased prevalence rate.

He pointed out that the youth, aged 18 to 35, had a prevalence rate of 2.37 percent, while those aged 36 to 60 had a prevalence rate of 2.33 percent. Along with other investigators and participants, Professor Makumbi emphasized the need for further studies to identify driving factors and take equitable action.

Dr. Fredrick E Makumbi, Associate Professor and a Ugandan Principal Investigator speaking at the dissemination meeting.
Dr. Fredrick E Makumbi, Associate Professor and a Ugandan Principal Investigator speaking at the dissemination meeting.

Dr. Angelina Kakooza Mwesige, a Co-Principal Investigator for Uganda who is also a Senior Lecturer and Paediatric Neurologist in the Department of Paediatrics and Child Health, Makerere University School of Medicine noted interesting gender regional variations of epilepsy with higher prevalence in women compared to men.

In the Eastern region, the prevalence rate was higher in females at 2.40% compared to males at 1.97%. Similarly, in the Central region, the prevalence rate was 1.81% in females and 1.53% in males. In the Northern region, the prevalence rate was 1.33% in females compared to 1.37% in males, while in the Western region, it was 1.54% in females and 1.72% in males.

Dr. Angelina Kakooza Mwesige, a Co-Principal Investigator for Uganda who is also a Senior Lecturer and Paediatric Neurologist in the Department of Paediatrics and Child Health, Makerere University School of Medicine.
Dr. Angelina Kakooza Mwesige, a Co-Principal Investigator for Uganda who is also a Senior Lecturer and Paediatric Neurologist in the Department of Paediatrics and Child Health, Makerere University School of Medicine.

This revelation according to Dr. Kakooza has prompted further consideration for conducting a specialized study to investigate the underlying factors contributing to this statistic.

“We found the overall prevalence rate is 1.73% in female compared to 1.63% in male. We do not know the reason yet but we are investigating this. Also, what we found out, the medicine that can help treat this disease and the trained specialists are not enough. We need to ensure equal and free access to medicine for all. I appeal to all Ugandans, a person with this disease, just like any other disease deserves our support and care,” said Dr. Kakooza.

Dr. Daniel Kyabayinze, the Director of Public Health at the Ministry of Health -Uganda, thanked the researchers for the great study and acknowledged that epilepsy requires lifelong treatment and highlighted the need to continuously provide treatment for all those affected.

According to Dr. Kyabayinze, the government plans to use the study’s findings to estimate the treatment needs, and Kyabayinze expressed confidence that further examination by Makerere University School of Public Health’s partners will help identify associated factors, such as potential agents or organisms, that can be modified to combat epilepsy. He also noted that while some individuals are already receiving treatment, many Ugandans face challenges in affording the necessary treatment for epilepsy.

Dr. Kyabayinze emphasized the importance of placing mental health specialists in various locations across the country to ensure access to services, stating, “There is also a need to intensify sensitization efforts to avoid stigmatizing people with epilepsy and ensure they receive the services they need.”

Dr. Daniel Kyabayinze, the Director of Public Health at the Ministry of Health -Uganda during the dissemination meeting at Golden Tulip Hotel in  Kampala.
Dr. Daniel Kyabayinze, the Director of Public Health at the Ministry of Health -Uganda during the dissemination meeting at Golden Tulip Hotel in  Kampala.

Ms. Nina Mago, Founder and Program Advisor of Purple Bench Initiative, underscores the need policy makers to prioritize healthcare needs of individuals with epilepsy to needs of people with epilepsy. She emphasizes affordable access to good quality medication.

“When you have medication, you have less seizures and you become more confident on being independent, to participate in activities which may include going to school, holding up a job, social interaction but all this is possible when there is also strong awareness,” says Nina.

Ms. Mago, says epilepsy is a life-threatening condition; “I came up with a connotation of a phone battery, as a notification of battery low shows up, equally relates to a life about to be lost.”

Dr. Olaro Charles, the Director Health services – Clinical in the Ministry of Health stated that epilepsy remains one of the common mental health conditions in Uganda. He said that they have just concluded a joint review mission and found out that from all their mental health facilities, epilepsy constitute to almost 55.4% of patients.

“If you look at 2019/2020 they were about 314,000 then came to about 340,000 and then last year it was 251,000. This mapping however is very important because it helps us to plan for care. If we do the same in those regions with high prevalence, we may be able to plan well”. Dr. Oralo.

Dr. Sarah Nekesa, Executive Director of Epilepsy Support Association Uganda, called on members of Parliament to increase the budget for mental health drugs, including epilepsy medication, and ensure their availability. She emphasized the need for integrating epilepsy services with other healthcare services to improve accessibility.

Dr. Sarah Nekesa, Executive Director of Epilepsy Support Association Uganda at the dissemination meeting. 
Dr. Sarah Nekesa, Executive Director of Epilepsy Support Association Uganda at the dissemination meeting. 

Additionally, Dr. Nekesa highlighted the importance of grassroots awareness to combat stigma, and urged the government to allocate adequate human resources and support from health workers to encourage peer talks and build confidence among people living with epilepsy.

“We should increase the drug availability in health facilities and make sure that a person with epilepsy is able to get medication whenever they need it. Epilepsy is not understood by everyone so if everybody understands epilepsy it would be easier for treatment and stigma to go down and integration of epilepsy in every service that is given to the community”. Said Dr. Nekesa.

Participants in a group photo at the Epilepsy National Prevalence Study Dissemination and Dialogue meeting held on Wednesday, April 5, 2023 at the Golden Tulip Hotel in Kampala.
Participants in a group photo at the Epilepsy National Prevalence Study Dissemination and Dialogue meeting held on Wednesday, April 5, 2023 at the Golden Tulip Hotel in Kampala.

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MakSPH, MOH and JMS Lead National Efforts to Build a Resilient Health Supply Chain

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Participants in the stakeholder consultative workshop convened by MakSPH to guide the research component of the initiative on Monday, 10 November, at Kabira Country Club. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.

Kampala, 11 November 2025 —Makerere University School of Public Health (MakSPH), the Ministry of Health (MoH) and Joint Medical Stores (JMS) have launched a project to boost Uganda’s health supply chain. Backed by the Gates Foundation, it aims to improve emergency deliveries and use data to ensure lasting resilience.

The intervention began on Thursday, 6 November, with the flag-off of emergency distribution of medicines and health supplies at JMS in Nsambya. Under a sub-award from MakSPH, JMS is leading warehousing, distribution, redistribution of essential commodities, reverse logistics, and technical support to health facilities, including digital training for over 1,100 facilities in the Integrated Online Ordering System. The operation aims to deliver USAID-supplied medicines that had remained in storage since donor support was suspended earlier this year, preventing expiry and restoring last-mile delivery across the country.

Building on this, MakSPH convened a stakeholder consultative workshop on Monday, 10 November, at Kabira Country Club to guide the research component of the initiative. Officials from the Ministry of Health, development partners, and health logistics experts reviewed the scope of a new study on strategic analytics to strengthen a sustainable and resilient health supply chain. The consultation focused on refining research questions to ensure alignment with national priorities and stakeholder needs.

Dr. Suzanne Kiwanuka, Associate Professor and Head of the Department of Health Policy, Planning, and Management (HPPM), stressed the need for practical, evidence-based collaboration.

“Our commitment is to make sure that whatever evidence we generate is useful. We want perspectives on governance, implementation, and the frontline, because when the supply chain isn’t functioning, a lot goes wrong,” said Prof. Kiwanuka.

Dr. Suzanne Kiwanuka, Associate Professor and Head of the Department of Health Policy, Planning, and Management (HPPM), speaking at the inaugural consultative meeting with stakeholders at Kabira Country Club on Monday, November 10, 2025. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.
Dr. Suzanne Kiwanuka, Associate Professor and Head of the Department of Health Policy, Planning, and Management (HPPM), speaking at the inaugural consultative meeting with stakeholders at Kabira Country Club on Monday, November 10, 2025.

The Ministry of Health has welcomed ongoing support from partners to stabilise the supply chain.

“I want to draw attention back to our 10-year health supply chain roadmap. Despite disruptions, we made important milestones in the first five years, and with support from Makerere University School of Public Health and the Gates Foundation, we are now focused on understanding challenges and building a resilient, sustainable supply chain,” said Dr. Ajulong Martha Grace, Assistant Commissioner, Pharmaceutical Supply Chain and Logistics.

Dr. Ajulong Martha Grace, Assistant Commissioner, Pharmaceutical Supply Chain and Logistics submitting during the meeting. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.
Dr. Ajulong Martha Grace, Assistant Commissioner, Pharmaceutical Supply Chain and Logistics submitting during the meeting.

Over the past decade, Uganda’s health supply chain has made steady progress under the 10-Year Roadmap for Health Supply Chain Self-Reliance (2021/22–2031/32), which sets out a vision for a self-reliant, efficient, and transparent system that ensures uninterrupted access to essential medicines. Efforts have focused on increasing financing, digitising logistics, strengthening local manufacturing, and expanding infrastructure.

Despite these gains, the system remains vulnerable. Limited financing, capacity gaps at subnational levels, and poor commodity reporting have contributed to stockouts and wastage. Heavy reliance on donor support, compounded with back-to-back shocks, has left Uganda’s health system exposed to shocks, such as the recent suspension of USAID support, which disrupted last-mile delivery to over 530 private not-for-profit health facilities.

Official flag off, Dr. Bildard Baguma, Executive Director of Joint Medical Store, Ms. Pamela Achii, Procurement and Supply Chain Management Specialist at Ministry of Health and Prof. Rhoda Wanyenze, the Dean, Makerere University School of Public Health and Principal Investigator of the Project at JMS offices in Nsambya last week. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.
Official flag off, Dr. Bildard Baguma, Executive Director of Joint Medical Store, Ms. Pamela Achii, Procurement and Supply Chain Management Specialist at Ministry of Health and Prof. Rhoda Wanyenze, the Dean, Makerere University School of Public Health and Principal Investigator of the Project at JMS offices in Nsambya last week.

Commodities worth more than UGX 79 billion have remained in storage, risking expiry and could potentially reverse service delivery gains. The Gates Foundation’s support comes at a critical moment to stabilise last-mile distribution while generating analytics to address deeper structural challenges.

“Before these financial disruptions, our public sector supply chain was already under intense pressure to meet rising last-mile demands. The current challenges are a critical opportunity to address long-standing bottlenecks, improve delivery of essential medicines, strengthen real-time monitoring, and build a more sustainable health system in Uganda,” said Timothy Musila, a Health Policy, Planning and Financing Specialist.

Timothy Musila, a Health Policy, Planning and Financing Specialist speaking at the consultative meeting. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.
Timothy Musila, a Health Policy, Planning and Financing Specialist speaking at the consultative meeting.

MakSPH, in partnership with the Ministry of Health, will carry out Strategic Systems Analytics to strengthen Uganda’s supply chain. The research will examine financing gaps, fiscal space, operational inefficiencies, and performance at the subnational and last-mile levels.  This co-created evidence generation will also identify opportunities for sustainable financing and efficiency gains to reduce reliance on external aid and to guide reforms that ensure that essential medicines and products remain accessible to all Ugandans.

L-R: The project team, Timothy Musila, a Health Policy, Planning and Financing Specialist, Pamela Achii, Procurement and Supply Chain Management Specialist at the Ministry, and Dr. Suzanne Kiwanuka share notes shortly after the consultative meeting at Kabira Country Club, Kampala. Makerere University School of Public Health (MakSPH), Ministry of Health (MoH) and Joint Medical Stores (JMS) launched of project to boost Uganda’s health supply chain backed by the Gates Foundation to improve emergency deliveries and use data to ensure lasting resilience, flag off-6th November 2025, stakeholder consultative workshop-10th November 2025, Kampala Uganda, East Africa.
L-R: The project team, Timothy Musila, a Health Policy, Planning and Financing Specialist, Pamela Achii, Procurement and Supply Chain Management Specialist at the Ministry, and Dr. Suzanne Kiwanuka share notes shortly after the consultative meeting at Kabira Country Club, Kampala.

This work is spearheaded by Professor Rhoda Wanyenze, as the Principal Investigator, and Associate Professor Suzanne Kiwanuka, the Co-Principal Investigator/Research Technical Lead on the Makerere University side. Dr. Charles Olaro, Director General of Health Services at the Ministry of Health, is the focal person on a five-member steering committee overseeing the implementation. The team includes Pamela Achii, Procurement and Supply Chain Management Specialist at the Ministry, and Mr. Timothy Musila.

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Davidson Ndyabahika

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JASH2025 wraps with the 23rd Matthew Lukwiya Memorial Lecture and Kampala Declaration Statement

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Panelists moderated by ED IDI-Dr. Andrew Kambugu (Left) reflect on Dr. Lukwiya's legacy during the 23rd Matthew Lukwiya Memorial Lecture on 7th November 2025. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.

The 19th Joint Annual Scientific Health Conference (JASH) and Inaugural National Annual Communicable and Non-Communicable Conference (NACNDC) held at Speke Resort Munyonyo ended on Friday 7th November, 2025 with the 23rd Matthew Lukwiya Memorial Lecture and a Kampala Declaration Statement.

The joint conference that began on 3rd November, 2025 themed, ‘Unified Action Against Communicable and Non-Communicable Diseases’ was organised by Makerere University College of Health Sciences (MakCHS), Makerere University School of Public Health (MakSPH) and Ministry of Health (MoH). The meeting brought together representatives from Central Government, Ministry of Health, academia, civil society, local governments, private sector, development partners, professional associations, local governments and communities.

Kampala Declaration Statement

Dr. David Musoke, Assoc. Professor at MakSPH who was Co-Chair of the Organising Committee delivered the Kampala Declaration which defined the priorities/commitments of the delegates from the dialogue at the conference.

The declaration highlighted the background of setting the priorities as thus: 1. Uganda’s dual disease burden from communicable diseases (CDs) alongside the growing rise of non-communicable diseases (NCDs). 2. The biological, social and clinical intersections between CDs and NCDs, which compete for limited resources. 3. Threats posed by antimicrobial resistance (AMR), climate-sensitive diseases, zoonotic spillovers, and emergency outbreaks such as Ebola, COVID-19, and Marburg. 4. Uganda’s commitment to Universal Health Coverage (UHC), the Africa CDC’s New Public Health Order, the Sustainable Development Goals (SDGs), the International Health Regulations (IHR), the International Covenant on Economic, Social and Cultural Rights, and the Global Health Security Agenda (GHSA). 5. The integration of health services at facility level continues to face challenges due to high patient-to-health worker ratios and inadequate infrastructure, which impede the delivery of comprehensive, timely, and quality healthcare services;

Emphasizing the need to involve all stakeholders—including from education, agriculture, environment, engineering, urban planning, gender, as well as community and religious leaders, and others—in the fight against communicable and non-communicable diseases; 6. The persistent challenges in access to healthcare across the country due to delays in diagnosis and treatment-seeking, and emphasizing the urgent need to strengthen early detection, ensure timely access to quality healthcare, and enhance community awareness about prompt medical attention; 7. Protection and promotion of human rights are fundamental to ensuring health, dignity, and well-being for all citizens, as these rights form the  foundation of equitable access to quality healthcare services; 8. The global threat of antimicrobial resistance (AMR), now causing an estimated 700,000 deaths annually, and recognizing its strong link to self-medication, poor diagnostic capacity, and weak public health interventions; 9. Health policies and investments have focused more on curative than preventive care, underscoring the need to reinstate a strong prevention-oriented approach; 10. Many Ugandans remain inadequately informed about health issues affecting them and their role in promoting health within their communities; 11. Rapid industrialization, urbanization, and lifestyle changes are significantly contributing to the rising burden of NCDs;

The Kampala Declaration was presented as a shared call to action, a platform for sustained collaboration, and a blueprint for strengthening integrated and equitable health systems. The declaration is premised on the following priorities:

  • Multisectoral Collaboration and One Health Approach: Affirmation of the requirement for involvement of the whole-of-society and whole-of-government approach to accelerate disease prevention, health promotion, and self-care through evidence-based awareness.
  • Integrated, People-Centered Disease Prevention and Care: The urgent need to focus on people, not diseases, using a life-course approach and strengthening integrated service delivery across CDs and NCDs at all levels.
  • Strengthened Data, Research, and Policy Translation: Recognition of the importance of timely, interoperable, and disaggregated data to inform policy, financing, and implementation decisions. In addition, commit to collaboration between academic institutions, policymakers, CSOs, and community influencers to bridge the gap between research and practice.
  • Financing: Commit to advocate for increased domestic financing to progressively reduce dependence on external aid, ensuring predictable and sustainable resources for integrated disease prevention and care. Promote efficiency and accountability in health spending by strengthening budget tracking, performance-based financing, and public financial management systems. Support innovative financing mechanisms, including public-private partnerships, social health insurance, and community-based financing schemes to expand coverage and affordability.

Specific calls were directed to the various stakeholders respective to their mandates and roles.

Government of Uganda and the Ministry of Health: To accelerate implementation of integrated strategic plans for CDs, NCDs, and epidemic preparedness under a unified health systems approach; Institutionalize NACNDC–JASH as the official Annual Integrated National Health platform for disease dialogue and innovation, co-led by the Ministry of Health and academia; Mobilize domestic and international financing to strengthen primary healthcare, laboratory networks, and community systems; Enforce laws and policies aimed at preventing and controlling substance abuse nationwide.

Academia: Generate policy-relevant evidence and drive innovation in diagnostics, surveillance, and culturally appropriate care; Establish multidisciplinary working groups to connect research, clinical practice, and policy; Train health professionals in integrated, competency-based, and future-ready approaches; Create innovation hubs and partnerships linking academia, communities, and industry to co-develop scalable, people-centred solutions; Leverage technology and innovation to effectively address CDs and NCDs; and Prioritize locally led research focused on Uganda’s health realities, including NCDs, CDs, mental health, and climate-linked risks.

Development Partners and Donors: Align technical and financial support with Uganda’s integrated disease control priorities; Support the development of a national research agenda driven by local health needs; Strengthen health system resilience, digital transformation, and community-led interventions; and promote regional knowledge sharing, South-South collaboration, and local manufacturing of diagnostics and medicines.

 Private Sector and Civil Society: Engage in public-private partnerships to expand access to diagnostics, care, and innovation; Champion community-responsive models for disease prevention; rehabilitation, and continuity of care; Strengthen advocacy, accountability, and public education through multimedia and grassroots platforms; Raise public awareness on mental health, sickle cell disease, asthma, and diabetes, integrating these services into primary care and reducing stigma and discrimination.

In view of the background, priorities and expected action from the stakeholders as highlighted above, the declaration also endorsed the development and dissemination of: a National Integrated Disease Control Strategy, informed by best practices and policy dialogues from this conference; a Multisectoral Action Framework guiding collaboration among health, education, agriculture, environment, and finance sectors; A Monitoring Mechanism to track implementation and institutionalize annual

reporting on disease integration; and the continuation of joint annual NACNDC and JASH conferences to sustain momentum.

Setting the Pace

Through the conference, keynote speakers delivered addresses which set pace for the dialogue by participants at the conference.

Dr. Queen Dube, Lead – Newborn Programme Implementation, Policies and Standards at the World Health Organisation (WHO), Geneva and Co-Chair of Every Woman, Every Newborn (EWENE) Country Implementation Group highlighted the reasons for rising disease burden of NCDs across sub-Saharan Africa including industrialization and urbanization; shifting dietary patterns; improved means of transport and communication which converts to less movement.

Dr. Dube noted that, the poorer one is, the higher the risk of one dying due to an illness either through communicable or non-communicable diseases. She stressed the importance for a unified action against diseases as opposed to fragmentations or silos by different working groups of various diseases. Duplication of efforts spreads thin the available resources, yet more efficiency and effectiveness could be enjoyed, she added.

Her call for action was, ‘health is interconnected, our response must be to; collaboration saves lives; and together, we can build a healthier, more resilent world’.

Prof. Francis Omaswa delivers the keynote address. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Francis Omaswa delivers the keynote address.

Delivering his keynote speech on the final day of the conference, Prof. Francis Omaswa, Founder and Director – African Centre for Global Health and Social Transformation (ACHEST) reminded the delegates that, ‘it is up-to us to achieve our goals provided we commit to do what is expected of us in the best possible way’.

He questioned why Africa continues to lag behind in the global health indices considering the professionals present on the continent. ‘Inclusiveness, equity and working together is the way forward’, he advised.

Prof. Omaswa reminded the delegates that Uganda in particular achieved in areas like HIV/AIDS control, therefore the means we used then must be employed in fighting communicable and non-communicable diseases. He heighted that, some of the means included leadership at all levels, working together, for monitoring and reporting, engagement of youth through the means they respond to among others.

Prof. Francis Omaswa (2nd Right) with panelists that discussed his keynote address. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Francis Omaswa (2nd Right) with panelists that discussed his keynote address.

‘Let no one go to sleep, each one of us is a leader at our levels of responsibility and we must make sure that there is coordination and supportive supervision within the health system’, Prof. Omaswa reiterated.

In his keynote speech, Dr. David Serwadda, a Professor in the Department of Disease Control and Environmental Health at MakSPH reminded researchers and academia the importance of their work to disease prevention and control. He stressed that the link between research and implementation is critical for a unified action, and there bridging the gap must be intentional.

Prof. David Serwadda delivers his keynote address on "Health Systems Resilience Amidst Global Funding Cuts: What African Countries Must Do". Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 6th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. David Serwadda delivers his keynote address on “Health Systems Resilience Amidst Global Funding Cuts: What African Countries Must Do”.

23rd Dr. Matthew Lukwiya Memorial Lecture

Dr. Matthew Lukwiya is remembered for his leadership and selflessness as a Ugandan physician at the forefront during the Ebola virus disease outbreak in Uganda in 2000 until de succumbed to the disease. He was the supervisor at St. Mary’s Hospital Lacor, outside Gulu City, Uganda; Gulu district was an epicentre of the disease at the time.

As has been the case at the previous JASH conferences, the 23rd edition of the Matthew Lukwiya Memorial Lecture was held on the final day of the conference, themed, “Identified Critical Gaps in the Response to Outbreaks”.

The session convened leading scientists, policymakers, community and health professionals to reflect on lessons learnt from past epidemics and chart strategies for stronger preparedness, response and resilience across the health system.

The Way forward

At the end of the meeting, delegates were advised that information from the meeting will be shared through a link on the MakSPH website and abstracts will be published as well.

Prof. Rhoda Wanyenze, Dean-MakSPH who also represented Prof. Bruce Kirenga, Principal-MakCHS thanked all participants for attending the dual conference and willingness to share information in support of integrating to improve Uganda’ Health System. She also thanked the organising committee and partners for the support leading to a successful conference.

‘What is it that touched you at this conference, what are the takeaways and I implore you to reflect on the discussions and create a change. This is not business as usual and let us make change.’, the Dean said.

Prof. Wanyenze handed the baton to the School of Medicine who will work with the MoH in organising the conference in 2026.

Closing by the Permanent Secretary

PS-MoH, Dr. Diana Atwine. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, 23rd Matthew Lukwiya Memorial Lecture, Kampala Declaration Statement and Closing Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
PS-MoH, Dr. Diana Atwine.

The conference was officially closed by Dr. Diana Atwine, Permanent Secretary-MoH. She highlighted five points for all of us to remember as takeaway from the dialogue.

  • All of us should innovate solutions for the challenges before us including innovative leadership. Uganda’s population growth remains high and the resources are not growing at same rate therefore challenges will continue to arise therefore innovation is necessary.
  • Inculcate a culture and mindset change and remember health change begins with each of us.
  • Integrate not verticalization because it is the right thing to do, leads to efficiency and gives results.
  • As government continues to explore means of resource mobilisation, smart investments in high impact activities and priorities are critical.
  • Call upon all of us, to implement the resolutions reached.

She thanked all stakeholders for the contributions made towards success of the conference.

Zaam Ssali

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2nd AI in Health Africa Conference, Not about Tech but the Vulnerable

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Hon. Dr. Monica Musenero (3rd Right) flanked by Left to Right: Mr. Ambrose Ruyooka, Dr. Rose Nakasi, Dr. Stella Kivila, Prof. Buyinza Mukadasi and Dr. Andrew Kambugu at the Conference Opening Ceremony on 6th November 2025. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.

The two-day 2nd Artificial Intelligence (AI) in Health Africa Conference that kicked off today in the Main Hall, Makerere University has been described as not being about technology but about people – the vulnerable communities bearing the burden of infectious diseases and other health challenges – and the promise AI holds as a panacea. Officially opened by Hon. Dr. Monica Musenero, Minister of Science, Technology and Innovation the conference will be held under the theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”.

Africa Must Enter the ‘Evil Forest’

In her now characteristic style of speaking from the heart, Hon. Dr. Musenero observed that Africa has from the first industrial revolution to the current fourth and impending fifth industrial revolutions experienced emotions ranging from non-recognition, rejection and skepticism to the current consumption with awe. This current emotion, though receptive unlike previous ones, continues to position Africa at a disadvantage economically, she noted.

Hon. Dr. Monica Musenero delivers her keynote address. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero delivers her keynote address.

“We are positioning ourselves to disadvantage in skill; we have positioned ourselves at the consumption end and we’ve stood in awe of this technology,” she observed, using the example of the amount of admiration a user who whips out the latest iPhone 17 attracts from those around them. “We respect you for your iPhone 17, but I would be happier if you were able to design and manufacture iPhone 5” intimated Hon. Dr. Musenero.

The Minister urged fellow scientists to wake up to the realization that the future of Africa lies in their hands. “We can no longer be passive participants, we can no longer reside on the shallow end of science; we must be willing, as I said when I was here last week, to enter the ‘evil forest’”.

Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony.

The ‘evil forest’ is Hon. Dr. Musenero’s analogy of Africa’s perception of current technology ecosystem drawing parallels with scenes often dramatized by Nigerian Movies. She notes that though depicted in these movies as scary and potentially dangerous, the ‘evil forest’ is loaded with hidden treasures, necessitating resilience and wisdom for one to navigate the pitfalls until they discover the treasure trove. Upon discovery, the value of this treasure has the potential to turn around the fortunes of the family, community or entire kingdom. Entering the ‘evil forest’ therefore, is her way of encouraging scientists to go beyond adapting imported technology for local use to understanding how it works enough to develop homegrown solutions.

Building AI Capacity through Synergy

Representing the Vice Chancellor, Prof. Barnabas Nawangwe, the Academic Registrar, Prof. Buyinza Mukadasi concurred with Hon. Dr. Musenero that Uganda needs to accelerate investment capacity in AI, if it is to be used as tool to manage health challenges. He nevertheless underlined the steps Makerere has undertaken to close the gaps by hosting units such as the Infectious Diseases Institute (IDI), AI and Health Lab, Innovation Pod, while working with various partners.

Prof. Buyinza Mukadasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi.

“We want to renew our commitment that we shall continue to translate our research findings into service delivery and products that improve the livelihoods of our people,” pledged Prof. Buyinza, who also noted that this will be undertaken within institutional ethical guidelines and policies, bolstered by good practices and recommendations arising from the conference.

Taking cognizance of contributions of various partners to strides made so far, the Permanent Secretary Ministry of ICT and National Guidance, Dr. Aminah Zawedde who was represented by Mr. Ambrose Ruyooka, the Ministry’s Head of Department of Research and Development, thanked the Makerere University AI Health Lab, IDI, Health AI for All Network, the Research and Innovation Fund, the African Population and Health Research Centre, and the Mastercard Foundation for convening the second edition of the conference.

“This year’s theme aligns perfectly with Uganda’s digital transformation vision. It reminds us that while innovation is powerful, true progress lies in ensuring it is equitable, ethical, locally relevant, and accessible to all” read Dr. Zawedde’s remarks.

Mr. Ambrose Ruyooka. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Mr. Ambrose Ruyooka.

She noted that when used responsibly, AI empowers healthcare workers to do more with greater precision and efficiency while extending services to under-served communities, essentially amplifying their impact whilst preserving the essential human touch that defines care. Dr. Zawedde reiterated the Government of Uganda’s commitment to positioning AI as a catalyst for national development and improved service delivery through the national AI governance framework. “By the end of 2025, we expect to reach a decision on whether to adopt a comprehensive AI policy or a flexible, sector-led regulatory approach.”

Referring to projects already underway at the College of Computing and Information Sciences (CoCIS), the Principal, Prof. Tonny Oyana underscored the great promise AI holds for not only improving affordability but also diagnosis of disease. He nevertheless called for targeted investment in data centres so as to build the required capacity to process the large amount of data that AI thrives on.

Prof. Tonny Oyana. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Tonny Oyana.

The Executive Director IDI and conference Co-Chair, Dr. Andrew Kambugu described the conference timing as “impeccable”. Citing a recently convened conference on Communicable and Non-Communicable Diseases that discussed Universal Health Coverage, he shared “there are people in this country who are one step away from disaster because of health.”

He therefore paid tribute to his conference Co-Chair, Dr. Rose Nakasi, whose AI-automation work with the light microscope, one of game-changing inventions in human medicine to-date, has improved precision, accuracy and efficiency in diagnosis of malaria, tuberculosis and cancer in healthcare facilities. Dr. Kambugu therefore urged his audience to always be eager to learn about the capabilities game changing tools such as AlphaFold.

Dr. Andrew Kambugu. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Andrew Kambugu.

“Our African Centre of Excellence in Bioinformatics & Data Intensive Science (ACE) in collaboration with CoCIS has been one of the first trainers of AlphaFold in Africa” remarked Dr. Kambugu. He added that the to ensure inclusive training ACE has attracted funding to support the She Data Science (SHEDS) project, an initiative that offers MSc and PhD fellowships to Ugandan women in the fields of data science and bioinformatics, with a strong emphasis on health data.

Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left). 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left).

How Ocular is shaping healthcare

Conference Co-Chair and Principal Investigator of Ocular, Dr. Rose Nakasi noted that their project that aims at empowering healthcare professionals with AI-powered microscopy was motivated by the fact that wrong diagnoses have a cascading effect on prescription, treatment, recommendation and surveillance services. “Where health practitioners have been taking 30 minutes or more to diagnose malaria, and days to diagnose cancers, we are slashing down that time to literally 5 seconds to diagnose and make a recommendation.” She added.

Dr. Nakasi added that beyond diagnosis, the Ocular project is supporting the Ministry of Health with more precise surveillance and monitoring of diseases by quicker augmentation of information for faster roll-out of interventions as opposed to current weekly or monthly reporting period required by the Digital Health Information System (DHIS 2).

Dr. Rose Nakasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Rose Nakasi.

“The beauty about AI is that it has the capability not to just learn with one dataset but also provide insights on different pieces of data – for diseases such as malaria where climate has an effect, we want to integrate climate datasets and seasonality aspects so that interventions by Government are timely and targeted to specific locations.”

The Ocular project exhibition setup. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
The Ocular project exhibition setup.

Beyond the plenary sessions, the 2nd AI in Health Africa Conference will feature abstract presentations, a Makerere AI Health Lab Showcase, Breakout Sessions, Workshops, Masterclasses and a hackathon for prototypes developed during the conference. Please see downloads for a detailed concept and programme.

Mark Wamai

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