The Executive Director MUCHAP and Site Leader IMHDSS-Dr. Dan Kajungu (Left) with staff from the Makerere University Biomedical Research Centre Limited (MakBRC) during their visit to the MUCHAP premises in Iganga.
MUCHAP, the Makerere University Center for Health and Population Research is a research and research training platform owned by Makerere University. MUCHAP runs and manages the Population-based Cohort of Iganga Mayuge Health and Demographic Surveillance Site (IMHDSS). The goal of the research platform is to provide longitudinal population-based social-economic and health data to monitor, track important health indicators and population changes that allows evidence-based decision-making for planning and policy development.
Ongoing Studies and Projects
Minimally Invasive Tissue Sampling (MITS) study – is aimed at determining the cause of death using MITS. Target population is children under five (5) years.
‘EMERALD’ quantitative study – Targeting 5,000 women of reproductive age who have had a pregnancy in the last 2 years, it is aimed at assessing the health care capacity for disabled women in the study area.
Adolescent health study – targeted 1,200 boys and girls between the ages of ten (10) and nineteen (19), to determining the reproductive life-style of adolescents, substance use and nutrition practices.
Data linkage system – for morbility surveillance. It includes the HDSS population served by Busowobi Health Center III Iganga.
NIRA-MUCHAP death registration study – a partnership to harmonize and improve death registration in a selected population under the surveillance area of IMHDSS.
Excess mortality study – to characterize all-cause (and cause-specific) mortality rates and trends, by age and sex, across a range of rural and urban settings under continuous health and demographic surveillance in order to understand the excess mortality of the COVID-19 pandemic in key LMICs.
RELAB-HS/USAID Network of Care (NoC) project – purpose is to strengthen the health system in relation to provision of rehabilitation services and care for persons with disabilities identified from the HDSS community.
IDAIR- Citizen Science study – an artificial intelligence (AI) research using citizen participatory approaches for pandemic preparedness and response.
Scientific Conferences and On-site Engagements
Makerere University Joint Annual Scientific Health (JASH) Conference: MUCHAP had one oral presentation and three Poster presentations.
Excess mortality data-analysis workshop: Took place at Wits School of Public Health in Johannesburg, South Africa from 28th November to 2nd December 2022.
Conference on Public Health In Africa (CPHIA) organised by Africa CDC: Was held from 13th to 15th December 2022 in Rwanda and brought together African researchers and scholars to showcase research outputs on public health challenges including COVID-19 and Ebola.
Other MUCHAP Engagements
MUCHAP participated in the WHO/MoH national polio immunization assessment survey using Lot Quality Assurance Sampling method (LQAS). Field Surveyors were trained and deployed in various districts across the country to collect household-level data.
In August 2022, MUCHAP was engaged in a research collaboration to establish a network of care for persons with disability.
MUCHAP plans to establish a community laboratory. The building was built with funding from Pfizer International. Makerere Biomedical Research Centre (MakBRC) visited the offices to assess the feasibility of supporting the completion of the laboratory. The laboratory will support preprocessing and storage of samples for various biomedical research studies utilizing the MUCHAP platform.
Highlight on Finances
Snapshot of Outputs
Reproductive health outcomes during COVID-19 years in Rural Uganda
Students and researchers from Makerere University and other institutions pitched 12 innovations addressing challenges in healthcare, clean energy, agriculture, waste management and community resilience during the inaugural Falling Walls Lab Kampala, held at the School of Public Health Auditorium, Makerere University.
The competition brought together emerging innovators to present solutions to practical challenges through a three minute pitch, followed by questions from a panel of judges.
Modelled on the Falling Walls format that originated in Berlin, the event required each participant to identify a “wall” a problem or barrier, and demonstrate how their innovation seeks to break it down.
Mudhasi wins with newborn jaundice screening device
Andrew Mudhasi of Makerere University emerged as the overall winner with a score of 90 per cent for a low cost medical device designed to improve newborn jaundice screening across different skin tones.
Overall competition winner Andrew Mudhasi (left) receives his first Place award certificate for his innovation
Mudhasi explained that the device uses optical sensor technology and a skin tone targeting algorithm to provide a rapid reading, with the aim of helping nurses and clinicians identify jaundice more efficiently.
During questions from the jury, Mudhasi said the device had not yet been tested on actual babies but had undergone laboratory testing using simulated skin tones.
He reported an accuracy rate of 94 per cent when the device was compared with laboratory spectrophotometers.
The innovation is intended initially for use in clinics and hospitals, with Mudhasi saying the team is also considering a version that could eventually allow mothers to screen babies at home.
Mudhasi’s innovation has previously received recognition at the African Business Concept Challenge and the iF Design Student Award, according to his presentation.
Rhonda’s innovation tackles diaper waste
Rhoda John of the University of Nairobi emerged in second place with 89.6 per cent for an innovation addressing the problem of used diaper waste.
Rhondah John pitches her innovation repurposing diaper waste into soil moisture retention
Under the theme “Breaking the wall of diaper waste and drug soils,” Rhonda explained that her team extracts sodium polyacrylate, the absorbent polymer found in diapers, and replaces the sodium with potassium.
The resulting potassium based superabsorbent material is designed to act as a “water battery” in soil by absorbing and retaining water for plants during dry periods.
John said testing showed a 99 per cent increase in germination and a 23 per cent increase in drought resistance.
The innovation also seeks to reduce the amount of used diapers ending up in landfills and the environmental effects associated with their decomposition.
During the question and answer session, John explained that her team was working with government environmental officials in Nairobi on a pilot collection system to address the challenge of gathering used diapers at scale.
Mahera takes third place with herbal peptic ulcer treatment
Stuart Mahera of Makerere University finished third with 86.2 per cent for a herbal formulation targeting peptic ulcers.
Stuart Mayira (left) receives his 3rd Place award certicate at the school of Public Health Auditorium.
Presenting under the theme “Breaking the wall of Nature and Modern Medicine,” Mahera argued that conventional treatment for peptic ulcers can involve multiple medicines and may be associated with side effects and antimicrobial resistance.
His proposed formulation, MARAC capsules, is intended as a monotherapy, combining properties required for peptic-ulcer treatment in a single capsule.
Mahera said his team had carried out quality control work, including characterisation and dose quantification, and had conducted preclinical trials on laboratory mice.
He also told the jury that an application had been submitted to the National Drug Authority as the team awaits the next stage of the regulatory process.
According to Mahera, the proposed seven day treatment would cost about Shs21,000, compared with the existing 14 day treatment approach.
Innovators present solutions to practical challenges
The remaining presentations covered a wide range of challenges.
Esther Nakungu of Utamu University presented Agri-Track, a digital record keeping solution intended to improve visibility, accountability and management of farm operations and financial information.
Dr. Jimmy Chachiga, a Makerere University participant, presented a solar photovoltaic cooker with a heat storage system designed to provide a cleaner and more reliable cooking option during both sunny and non sunny periods.
His presentation focused on reducing dependence on biomass fuels and addressing the challenges associated with intermittent solar energy.
Abdul Noor Luttamaguzi, a PhD student and senior government fisheries officer, presented a mobile application aimed at helping fish farmers and extension officers report, track and manage disease outbreaks.
Henry Duke Tamale presented a herbal cream targeting antibiotic resistant biofilm infections associated with diabetic foot ulcers.
Marvin Seruwu proposed adapting existing near infrared brain monitoring technology to help detect extra-axial brain bleeds in health facilities where access to CT and MRI equipment is limited.
His proposal seeks to repurpose existing technology towards a diagnostic need that could be particularly important in settings where advanced imaging facilities are not readily available.
Kennedy Kisame presented a poultry alert and diagnosis system combining satellite weather information with computer vision disease detection. The proposed system could be accessed through a smartphone application, SMS or USSD, making it potentially usable by farmers with limited internet access.
Frank Atwiine proposed a solar powered mobile diagnostic van designed to bring ultrasound and other diagnostic services closer to rural communities.
Johnson Makmot, a software and blockchain developer, presented a platform that combines GPS tracking and blockchain-based tokens to incentivise and verify plastic-waste collection in Kampala.
Dr. Nelson Ndugu, from a partner university, presented an artificial intelligence tool designed to translate agricultural research publications into local Ugandan languages and generate voice notes for radio-based extension delivery.
The final presentation came from Dr. Juliet Akola, a Ugandan post doctoral researcher at Mangosuthu University of Technology in South Africa.
Akola presented a community digital resilience initiative focused on mapping risks in Kampala’s informal settlements, including flooding, fire, poor sanitation, waste management and inadequate infrastructure.
Her proposal seeks to combine local community knowledge with geographical information systems and link identified risks to action plans involving municipalities and other stakeholders.
Nawangwe calls for more investment in innovation
Closing the event, Prof. Nawangwe congratulated all the participants and described their presentations as an important beginning for Makerere University, Uganda and the wider region.
Vice Chancellor, Prof. Banabas Nawangwe giving his remarks
Drawing on his experience attending the Falling Walls conference in Berlin, the Vice Chancellor said initiatives of this nature are important because innovation will play a major role in determining the future of countries.
He encouraged participants to make their pitches more precise by clearly identifying the problem they are addressing, explaining their proposed solution and demonstrating what they have already achieved.
Prof. Nawangwe also welcomed the participation of innovators from other universities and countries, noting that the Kampala event had attracted participants beyond Makerere.
He thanked the Africa Office of the Falling Walls Foundation for its role in bringing the initiative to Makerere and encouraged continued support for innovation.
The Vice Chancellor further linked innovation to Uganda’s growing youth population and the need to develop home-grown solutions to address challenges such as youth unemployment.
The inaugural Falling Walls Lab Kampala ultimately provided a platform for innovators to move ideas beyond the classroom and laboratory and demonstrate how research, technology and creativity can be applied to challenges affecting communities.
What will it take for Uganda’s health financing to match the scale of its ambitions? How does a nation ensure that the systems it builds are ones the government can fully own, sustain, and grow? And who are the leaders being shaped today to carry this work into the future?
The inaugural issue of the Makerere University School of Public Health (MakSPH) newsletter follows these questions through six months of research, partnership, and institutional growth. Inside: MakSPH’s role in the national dialogue on sustainable health financing; the milestone handover of 16 MakSPH-METS digital health systems, built over 15 years, to Ministry of Health stewardship; and the research and academic investment shaping the School’s next phase of growth.
The edition also covers Vice-Chancellor’s Research Excellence Awards for MakSPH faculty, a new CARTA doctoral cohort, progress on the School’s new building, fresh leadership in the Department of Disease Control and Environmental Health, expanding partnerships in malaria, environmental health, and maternal care, and MakSPH students stepping into leadership across Makerere‘s 92nd Guild Government.
Research has the greatest value when it moves beyond publication to improve lives.
At Makerere University’s Centre of Excellence for Maternal, Newborn and Child Health (MNCH Centre) housed at Makerere University School of Public Health, research, partnerships and innovation are being translated into action to strengthen reproductive, maternal, newborn, child and adolescent health (RMNCAH) in Uganda and beyond.
Welcome to the September MNCH Centre e-Post 135.
This month, we spotlight how evidence is informing action across reproductive, maternal, newborn, child and adolescent health (RMNCAH) at the centre.
Explore how Centre researchers and partners are advancing innovations to reduce early perinatal mortality, how Makerere University through the Centre and WHO are strengthening capacity to monitor health inequalities, and how the Centre and its partners are leveraging AI to strengthen health systems and improve malaria surveillance.
Discover what these innovations could mean for scale, stronger health systems and greater impact.