The Executive Director MUCHAP and Site Leader IMHDSS-Dr. Dan Kajungu (Left) with staff from the Makerere University Biomedical Research Centre Limited (MakBRC) during their visit to the MUCHAP premises in Iganga.
MUCHAP, the Makerere University Center for Health and Population Research is a research and research training platform owned by Makerere University. MUCHAP runs and manages the Population-based Cohort of Iganga Mayuge Health and Demographic Surveillance Site (IMHDSS). The goal of the research platform is to provide longitudinal population-based social-economic and health data to monitor, track important health indicators and population changes that allows evidence-based decision-making for planning and policy development.
Ongoing Studies and Projects
Minimally Invasive Tissue Sampling (MITS) study – is aimed at determining the cause of death using MITS. Target population is children under five (5) years.
‘EMERALD’ quantitative study – Targeting 5,000 women of reproductive age who have had a pregnancy in the last 2 years, it is aimed at assessing the health care capacity for disabled women in the study area.
Adolescent health study – targeted 1,200 boys and girls between the ages of ten (10) and nineteen (19), to determining the reproductive life-style of adolescents, substance use and nutrition practices.
Data linkage system – for morbility surveillance. It includes the HDSS population served by Busowobi Health Center III Iganga.
NIRA-MUCHAP death registration study – a partnership to harmonize and improve death registration in a selected population under the surveillance area of IMHDSS.
Excess mortality study – to characterize all-cause (and cause-specific) mortality rates and trends, by age and sex, across a range of rural and urban settings under continuous health and demographic surveillance in order to understand the excess mortality of the COVID-19 pandemic in key LMICs.
RELAB-HS/USAID Network of Care (NoC) project – purpose is to strengthen the health system in relation to provision of rehabilitation services and care for persons with disabilities identified from the HDSS community.
IDAIR- Citizen Science study – an artificial intelligence (AI) research using citizen participatory approaches for pandemic preparedness and response.
Scientific Conferences and On-site Engagements
Makerere University Joint Annual Scientific Health (JASH) Conference: MUCHAP had one oral presentation and three Poster presentations.
Excess mortality data-analysis workshop: Took place at Wits School of Public Health in Johannesburg, South Africa from 28th November to 2nd December 2022.
Conference on Public Health In Africa (CPHIA) organised by Africa CDC: Was held from 13th to 15th December 2022 in Rwanda and brought together African researchers and scholars to showcase research outputs on public health challenges including COVID-19 and Ebola.
Other MUCHAP Engagements
MUCHAP participated in the WHO/MoH national polio immunization assessment survey using Lot Quality Assurance Sampling method (LQAS). Field Surveyors were trained and deployed in various districts across the country to collect household-level data.
In August 2022, MUCHAP was engaged in a research collaboration to establish a network of care for persons with disability.
MUCHAP plans to establish a community laboratory. The building was built with funding from Pfizer International. Makerere Biomedical Research Centre (MakBRC) visited the offices to assess the feasibility of supporting the completion of the laboratory. The laboratory will support preprocessing and storage of samples for various biomedical research studies utilizing the MUCHAP platform.
Highlight on Finances
Snapshot of Outputs
Reproductive health outcomes during COVID-19 years in Rural Uganda
The Sanger Prize presents a wonderful opportunity for genomics students in low and middle income countries, therefore the prize administrators are keen for the application information to reach as many eligible people as possible.
A Voice for Excellence, Equity and African Sovereignty
When Dr. Michael Makanga walked onto the stage at the 8th Galien Forum Africa in Dakar on 31 October 2025 to receive the Special Career Achievement Galien Prize, presented by President Bassirou Diomaye Faye under the theme Health sovereignty: an imperative for Africa, the moment carried weight beyond any medal or citation. “It is a celebration of a lifelong commitment,” he said, “but also a reminder of a responsibility I have never been willing to compromise: to inspire others to raise their voices for excellence, science, and equity.”
For more than two decades, Dr. Makanga has been a quiet architect of Africa’s health sovereignty. His work has unfolded far from cameras: in laboratories constrained by resources, in policy rooms where African priorities demanded a stronger voice, and in mentoring sessions with young scientists seeking reassurance that their ideas mattered.
Born and trained in Uganda, Dr. Makanga earned a Bachelor of Medicine and Surgery from Makerere University before pursuing a master’s degree and PhD at the Liverpool School of Tropical Medicine. His career spans nearly 30 years, encompassing tropical medicine, clinical trials in Africa and Europe, and senior international management roles. Since joining EDCTP in 2004, he has guided its growth as a unique Africa–Europe partnership, strengthening African capacity for high-quality, ethical clinical research while accelerating solutions for poverty-related diseases. Today, he leads the Global Health EDCTP3 Joint Undertaking under the EU’s Horizon Europe programme.
President Faye captured the essence of Dr. Makanga’s achievement: “Scientific excellence is not negotiable; it is earned. It underpins our credibility and our sovereignty.” For Dr. Makanga, the statement is a call to action. “I hope this recognition reminds us that Africa’s scientists and innovators can lead global health research with excellence and purpose. We owe it to the next generation to build the systems and confidence that make this possible,” he said.
Dr. Makanga’s peers describe him as a “builder”: someone who strengthens research systems, mentors emerging scientists, and fosters equitable partnerships long before “local ownership” became a policy buzzword. In his own words, the award honors his “career’s contribution to advancing Africa’s health sovereignty” while reinforcing his commitment to ensure younger scientists do not have to fight for legitimacy as previous generations did.
The 2025 Prix Galien Africa celebrated Dr. Makanga alongside innovators reshaping African science. La Ruche Health, a Côte d’Ivoire-based digital health platform, won for connecting users to certified providers through an AI-powered system. Senegalese computer scientist Adji Bousso Dieng received a special prize for applying artificial intelligence to the natural sciences, including spotting emerging viral variants using her “Vendi Score” tool. The awards were organised with the support of the Presidency of Senegal, the Gates Foundation, the West African Health Organization, and the Rockefeller Foundation, with a jury co-chaired by Dr. John Nkengasong and Professor Souleymane Mboup.
Yet the award’s true weight lies not in ceremony, but in its symbolism. Dr. Makanga’s career exemplifies how African scientists can lead, shape policy, and influence global health priorities when empowered and supported.
L-R: La Ruche Health (Côte d’Ivoire) innovator, President of Senegal, Bassirou Diomaye Faye, Dr Michael Makanga (Uganda) and Adji Bousso Dieng (Senegal)
Makerere University colleagues attest to this impact. Dr. Victoria Nankabirwa, a clinical researcher and epidemiologist, reflects: “EDCTP support allowed me to build multidisciplinary teams, enhance laboratory and trial infrastructure, and generate evidence relevant for policy and practice. It strengthened my scientific independence and expanded the long-term sustainability of my research, particularly on childhood vaccines.”
She adds, “Dr. Makanga’s vision and commitment have strengthened institutions, built capacity, and fostered equitable partnerships, enabling African investigators to lead complex studies that address the continent’s priorities. His recognition shows what is possible when scientists are empowered, trusted, and supported.”
Dr. Alex Kayongo, an immunologist at Makerere University, describes EDCTP support as “catalytic,” enabling advanced training and a platform to study microbiome–immune interactions in HIV-associated COPD. His work is shaping mechanistic insights and strengthening Uganda’s capacity for complex respiratory immunology research. “Global health funding is increasingly competitive, making EDCTP’s role even more vital,” he says. “Africa needs sustainable support for complex, lab-intensive research. Continued investment in infrastructure, leadership, and fair partnerships is essential if African institutions are to drive innovation and secure true scientific sovereignty.”
Dr. David Musoke, an associate professor of disease control, credits his EDCTP fellowship with deepening his malaria research and advancing his career. His studies combined housing improvements, environmental management, and behavioural measures to complement traditional malaria prevention, shaping practical, community-informed interventions. “Dr. Makanga’s contribution to African science has been tremendous, and his continued stewardship gives us confidence that evidence generated on the continent will increasingly shape policy and practice,” he observes.
Dr. Makanga’s impact is visible not only in individual careers but across institutions and nations. Through EDCTP, he has championed African-led trials, strengthened laboratory capacity, and fostered cross-country collaboration. Colleagues emphasize that his leadership has created a generation of African scientists who are confident, collaborative, and globally competitive.
“My experience with EDCTP-funded programmes has shown the transformative impact of African-led research,” Dr. Nankabirwa reflects. “Dr. Makanga’s vision and commitment have strengthened institutions, built capacity, and fostered equitable partnerships, enabling African investigators to lead complex studies that address the continent’s priorities. His recognition shows what is possible when scientists are empowered, trusted, and supported, inspiring the next generation of research leaders.”
Dr. Makanga’s recognition is a tribute to perseverance, vision, and mentorship: a scientist who kept going when resources were scarce, a leader who refused partnerships that treated Africans as subjects, and a mentor who reminded young researchers that they belong at the centre of global science.
As he stood among Africa’s leading innovators in Dakar, the message was unmistakable: Africa can lead, Africa must lead, and it will lead, through science, excellence, and equity.
Makerere University is proud to celebrate Dr. Michael Makanga, one of its distinguished alumni, on receiving the Special Career Achievement Prize of the Prix Galien Africa 2025. This honor recognises his exceptional leadership in medical research and his role in advancing African-led science. Through his work, Dr. Makanga continues to strengthen institutions, mentor emerging researchers, and amplify Africa’s voice on the global health stage.
Kalangala, an idyllic archipelago often romanticised for its sunsets, today witnessed a historic leap in healthcare. Makerere University Vice Chancellor, Prof. Barnabas Nawangwe, launched the Infectious Diseases Institute (IDI) Kalangala Clinical Research Centre—the island’s first modern research facility.
“This is more than a building; it’s a lifeline,” said Prof. Nawangwe. “IDI is not only Uganda’s leading health partner, managing over 20% of HIV cases, but research is first on its agenda. If people are not healthy, they can’t work—it’s useless to invest in anything else.”
Prof. Nawangwe unveils the Kalangala Facility plaque.
Kalangala ranks third in HIV prevalence nationwide at 13.1%, with fishing communities hardest hit. Until now, residents endured perilous boat rides to the mainland for advanced care. “Accessing healthcare has always meant a journey across waves—long, costly, and sometimes dangerous,” said District Chairperson Jajab Ssemakula. “You have not only invested in Kalangala; you have brought Makerere University to Kalangala.”
Supported by the Gates Foundation, the centre is part of a multinational HIV prevention study conducted across 31 sites in Kenya, South Africa, and Uganda. Its first mission: testing whether a monthly pill can protect adolescent girls and young women from HIV—a breakthrough that could transform vulnerable communities.
Prof. Barnabas Nawangwe addresses guests.
“This centre means access without barriers,” said Dr. Andrew Kambugu, IDI Executive Director. “Kalangala residents no longer need to travel long distances for clinical trials or advanced care.”
Dr. Andrew Kambugu.
Prof. Samuel Luboga, IDI Board Chairperson, reassured residents of IDI’s long-term commitment: “We are not a fleeting partner. This sentinel research centre aligns with our vision of freeing Africa from the burden of infectious diseases. The assurance I give Kalangala is—we are here to stay.”
Officials pose for a group photo shortly after the facility’s launch.
Henry Ssebunya, Deputy Resident District Commissioner, praised IDI’s innovation and consistency: “IDI has treated and cared for people living with HIV, deployed medical drones to deliver life-saving medicines, and now built a research centre. This is a new chapter for Kalangala.”
Prof. Nawangwe and other officials receive a guided tour of the facility.
From a sleeping sickness camp in 1906 to a cutting-edge research hub in 2025, Kalangala’s story is one of resilience, innovation, and hope.
“Makerere University Infectious Diseases Institute (IDI) Kalangala Clinical Research Centre, Officially inaugurated on 20th November 2025 by Prof. Barnabas Nawangwe, Vice Chancellor, Makerere University with funding from Gates Foundation.”