Veterinary & Biosecurity
An Interdisciplinary approach addressing Ticks and Tick-borne Diseases of cattle in Uganda
By Joseph Odoi
Globally, Ticks are the most important vectors of disease-causing pathogens in domestic and wild animals and tick-borne diseases (TBDs) are a major threat to both cattle and human health. Understanding the complex interactions within the microbiome is of great importance for understanding how tick-borne pathogens spread and cause disease.
Inspired by the need to generate evidence to inform policy around Tick borne Diseases, a team of researchers from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden, Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, conducted a study to assess diversity of ticks and their Tick Borne Diseases (TBDs) in Uganda from 2017 to 2021.
The researchers organised a dissemination of the project results workshop to stakeholders from various sectors on 27th February, 2023 held at the Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University.
Associate Professor Lawrence Mugisha, Co-principal investigator explained that the purpose of the workshop was to share the results of the different research outputs and discuss various ways to re-package the results for different target audiences and to influence policies for tick control strategies in Uganda.
Having set the scene for the workshop, Associate Professor Maja Malmberg, Principal investigator from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden provided a virtual overview of the Project tilted; Ticks and Tick Borne Diseases (TBDs) in Africa. She noted that the overall purpose of the project was to improve cattle health through increased understanding of the microbial community in cattle and ticks, by investigation of the microbial composition (microbiota) of ticks and how this affects transmission and disease development in cattle in Uganda. As part of the study, she noted that the research team were able to generate new knowledge on diversity of tick species, new viruses and highlighted public health implications of the findings. The project had a capacity building component through supporting masters and PhD students and several technical workshop during the project period.
Various presentations of the results from different studies under the project were made by the project investigators and the PhD student Dr. Steven Balinadi who successfully graduated in 2022.
Below are brief project results from the presentations made at the Workshop;
- A total of 15 different tick species were identified in the five study districts of Kasese, Hoima, Soroti, Gulu and Moroto representing different ecological zones. They also reported high tick burden on cattle from all the study districts. They found out the tick species R. appendiculatus (the brown ear tick), the vector for the causative agent for East Coast Fever (“Amashuwo”, “Amakebe”) was most common tick on cattle in all districts (51.79%) followed by A. variegatum (14.33%) and R. evertsi (8.23%) and continue to dominate tick distribution in Uganda. The team also found ticks that were not known to be in Uganda including Rhipicephalus afranicus that was recently described in South Africa and Rhipicephalus microplus, expanding its geographical zones found ion cattle in Gulu and Soroti districts.
- The team further identified 8 viruses from the blood of cattle suspected to be transmitted by ticks and mosquitoes belonging to 4 viral families (Flaviviridae, Peribunyaviridae, Reoviridae and Rhabdoviridae) and 6 genera (Hepacivirus, Pestivirus, Orthobunyavirus, Coltivirus, Dinovernavirus and Ephemerovirus) among 175 studied cattle. Four of the viruses were new and were tentatively named Zikole virus (Family: Flaviviridae), Zeboroti virus (Family: Reoviridae), Zebtine virus (Family: Rhabdoviridae) and Kokolu virus (Family:Rhabdoviridae). This contributes to the body of the new knowledge in the field of virology. However, they were quick to mention the public implications of all viruses and new viruses remains to be understood through more studies.
- Part of the research assessed cattle exposure to Crimean Congo Haemorrhagic Fever (CCHF) Virus a zoonotic disease of public health importance transmitted by ticks. The study found that 74% (500) of the studied cattle from five districts were exposed to the virus. This raises a big concern a potential source of infections to humans. This concern is verified by the results of investigating 32 CCHF confirmed human cases of the recorded outbreaks between 2013 and 2019. Of the 32 hospitalised human CCHF cases, 32% of them died. Most cases presented with fever (93.8%), followed by hemorrhage (81.3%), headache (78.1%), fatigue (68.8%), vomiting (68.8%) and myalgia (65.6%) and other symptoms. The researchers were able to characterise the CCHF viruses circulating in Uganda, a break through that can inform vaccine and diagnostic tool development.
- Further, looking at the ticks themselves using advanced technologies, ticks were found to carry several viruses most of the unknown and new. The team has at least found 20 new viruses in the ticks and the team will be conducting further studies to understand the implications of the so many viruses in relation to animal and human health.
The team presented potential Public Health Implications of their study results as:
• High diversity and burden of ticks infesting cattle in Uganda has potential for a high pathogen load
• Evidence for range expansion of some tick species; risk for disease emergence in naïve animal and human populations around the country
• Cattle in Uganda are harbouring numerous viruses including novel ones
• CCHF is widespread in Uganda, including where human cases have not been detected. And its endemicity does not overlap with the spatial distribution of Hyalomma ticks
Participants of the stakeholder’s dissemination workshop discussed the results and provided feedback. Out of the discussion, it was generally agreed and proposed that deliberate actions need to be undertaken if we are to address the current challenges posed by ticks and their tick-borne diseases. Participants emphasised the following areas that require immediate attention;
- The need for improved surveillance and diagnostic tools for emerging viruses in animals to prevent their transmission to humans.
- The need for the Government investment in advanced technologies and equipment for improved surveillance, detection, and rapid response to any emerging virus outbreak from ticks and their pathogens.
- There is need to understand the cultural and social context: Therefore, any policy or intervention aimed at preventing disease transmission should take into account the cultural and social practices of the communities involved.
- The government should engage with local communities, listen to their concerns, and incorporate their knowledge and perspectives in developing disease control policies.
- The government should prioritize research and development of strategies to control ticks and prevent tick-borne diseases in both humans and animals. This includes conducting awareness campaigns, developing policies, and providing resources to prevent tick infestation and tick-borne diseases.
- Employ One Health approach: that considers the interactions between human, animal, and environmental health.
- More funding and support for tick-borne disease research and control programs in Uganda and other high-risk areas.
- Integration of livestock and human health surveillance and control measures to prevent the transmission of tick-borne diseases.
- Development of community-based tick control strategies that incorporate local knowledge and practices to increase their relevance and effectiveness.
- Collaboration between government agencies, researchers, and communities to implement effective tick-borne disease control strategies.
In his remarks at the engagement, Dr. Kenneth Mugabi, a Senior Veterinary Officer at Ministry of Agriculture, Animal Industry and Fisheries congratulated the team of researchers for undertaking the value based research adding that it will help inform policy to address ticks and tick borne diseases in the country. He equally noted the urgent need for more innovation to discover and develop vaccines, therapeutics and diagnostics options to respond to the increasing challenges of ticks and tick-borne diseases. Additionally he equally thanked the study funders for partnering with Makerere University to undertake the study.
Dr. Ekwaro Obuku from Makerere University College of Health Sciences in his emphasized the importance of researchers tailoring research in a way that it speaks to policy makers adding that researchers should use all avenue to influence policy initiatives for public good. He equally proposed for the need for researchers to have a data bank around Ticks and Tick-Borne Diseases.
The stakeholders’ workshop attracted over 70 participants ranging from government officials, academia, media, farmers and one- health officials among others.
Key issues discussed by participants include; Policy brief to address Tick and Tick-Borne diseases, Development of community-based tick control strategies that incorporate local knowledge and practices,one-health approach in addressing ticks and Tick-Borne diseases ,Importance of engagement with local communities affected by ticks and Tick-Borne ,the need for effective communication by researchers to influence policy, need to develop diagnostic tools and model based surveillance for early detection and early warning about Vector borne diseases among others
PROJECT TEAM
Principal investigator: Dr. Maja Malmberg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Co-PI in Uganda: Assoc. Professor Lawrence Mugisha – Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda and Ecohealth Research Group, Conservation & Ecosystem Health Alliance, Uganda
PhD student: Mr. Stephen Balinandi – Uganda Virus Research Institute, Uganda and Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda
Professor Erik Bongcam Rudloff – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Dr. Erika Chenais – National Veterinary Institute, Sweden
Assoc. Professor Klara Fischer – Swedish University of Agricultural Sciences, Department of Rural and Urban Development, Sweden
Dr. Lidia Chitimia-Dobler – Bundeswehr Institute of Microbiology and University of Hohenheim, Department of Parasitology, Germany
Dr. John Pettersson – Uppsala University, Department of Medical Biochemistry and Microbiology, Sweden
Dr. Juliette Hayer – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Professor Mikael Berg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Dr. Giulio Grandi – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Assoc. Professor Ingrid Hansson – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Veterinary & Biosecurity
Prof. Clovice Kankya Assumes Leadership at the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB)
Prof. Clovice Kankya officially assumed leadership of Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, September 17, 2026, taking over from outgoing principal Prof. Frank Norbert Mwiine in a handover ceremony presided over by Chief Human Resources Officer Deus Mujuni.
Upon assuming office, Prof. Clovice Kankya has laid out a six-pillar vision to transform the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB). The vision focuses on shifting from lecture-based to competence-driven teaching, advancing impactful research that translates into innovation and national development.
Further, he said his leadership will support building valuable partnerships that strengthen staff capacity and global contribution. He emphasized treating people as the greatest resource by addressing staff attrition and fostering mentorship, while reinforcing governance and accountability to ensure institutional trust. Finally, he pledged to create a listening college with open communication channels between staff and students, positioning CoVAB as a hub of excellence, innovation, and impact.
Prof. Clovice Kankya, in his maiden address as Principal CoVAB, began with heartfelt appreciation: “I stand before you with a profound sense of gratitude, humility, and responsibility.” He pledged to confront challenges honestly, build on existing achievements, and transform ideas into measurable outputs. Emphasizing his leadership philosophy, he declared that it is anchored on “continuity where continuity serves, change where change is necessary, and innovation where innovation can create greater impact.”
A Call to Collective Action
Prof. Kankya urged students to challenge the college intellectually and prepare to become solution creators rather than job seekers. He called on staff for active participation and constructive criticism, and encouraged researchers and partners to form multidisciplinary teams tackling Uganda’s pressing problems.
Further, he pledged to lead with consultation, accountability, and consensus-building. “Today marks the beginning of a new chapter. It’s not a chapter that I write alone; it’s a chapter that we shall write together,” he said. “Together, let us move CoVAB from retention to practice, from knowledge to innovation, and from innovation to impact.”
Prof. Kankya envisions CoVAB as a hub of academic excellence, innovation, and impact — with improved infrastructure, digital transformation, enhanced staff development, and financial sustainability. His leadership is expected to strengthen academic programs, enhance resource mobilization, and steer the college toward greater influence in veterinary medicine and animal resources, both in Uganda and beyond.
Legacy of Prof. Frank Norbert Mwiine at CoVAB
Outgoing Principal Prof. Mwiine highlighted milestones during his tenure, including the construction of a 980-million-shilling hostel at Buyana Stock Farm, roofing of the CoVAB building, acquisition of a bus for student transport, provision of 500 lecture hall seats, and painting of the college building without drawing on university funds. Yet, he also pointed to persistent challenges such as staffing gaps, unimplemented departmental restructuring, and high staff attrition. He urged his successor to remain resilient, stressing that resource mobilization often comes with resistance and criticism.
The Chief Human Resources Officer for Makerere University, Mr. Deus Mujuni commended Prof. Mwiine for leaving an indelible mark on the college and urged Prof. Kankya to build on that legacy. He emphasized continuity, urging the new principal to consult past leaders and rely on institutional memory, while reminding staff to extend the same trust and dedication to the incoming leadership.
The Minister for Science, Technology and Innovation, Rt. Hon. Eng. Asiimwe Jonard, visited the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) during his maiden official visit to Makerere University, commending the tremendous research work ongoing at CoVAB and across the University.
In his remarks, the Minister noted that his visit to the University highlighted the pivotal role of research, technology, and innovation in shaping Uganda’s economic transformation and showcased Makerere’s capacity to translate groundbreaking scientific discoveries into practical solutions that address both national and global challenges.
The visit, held on September 16th, 2026, was anchored under the theme “Research Infrastructure, Emerging Technologies and Enterprise Creation.” It offered the Minister an opportunity to tour CoVAB’s state-of-the-art facilities at the Centre for Global Biosecurity and Biomolecular Technology (CeBioTech) and engage directly with faculty, researchers, and students. He commended the college for its tremendous contributions to animal health, food security, and biosecurity, emphasizing that these areas are vital to building a resilient and sustainable economy for Uganda.
While addressing college staff, researchers, and other stakeholders, the Minister emphasized that universities must serve as engines of innovation, moving beyond scholarly work to commercialization. He commended CoVAB’s vaccine development for both humans and animals, describing it as a cornerstone of Uganda’s biosecurity agenda. He further highlighted the importance of integrating social sciences into innovation, noting that project management and product development strategies are essential to fast-track research outputs into viable enterprises.
The Minister toured several flagship facilities at CoVAB, including the Central Laboratory Animal Research Facility, which provides laboratory animal services and pre-clinical trial support; RePROVaD, which designs recombinant proteins and subunit vaccines for emerging infectious diseases such as COVID-19 and Mpox; the Anti-Tick Vaccine project, which addresses the persistent challenge of ticks and tick-borne diseases affecting livestock productivity; and BIOMARKER, which develops antibody-based diagnostics to strengthen disease detection. These initiatives, he noted, demonstrate Makerere University’s capacity to contribute meaningfully to both national and global health challenges.
Looking ahead, the Minister outlined priority actions where CoVAB is expected to play a leading role. These include advancing veterinary innovations toward certification and commercialization, leveraging artificial intelligence to strengthen Uganda’s pathogen economy, positioning veterinary science as a driver of agro‑industrialization, developing sustainable models for shared diagnostic and biosecurity laboratories, and providing commercialization support for innovators in areas such as intellectual property, regulation, standards, and market access. By focusing on these areas, he emphasized, CoVAB will not only enhance Uganda’s scientific capacity but also accelerate the country’s journey toward economic resilience and prosperity.
Asiimwe pledged continued support for Makerere University and encouraged the development of structured University–Industry exchange models to ensure veterinary research translates into enterprise creation. He also emphasized the importance of self-sustainability for research centers, noting that revenue generation is key to long-term impact.
The Vice Chancellor, Prof. Barnabas Nawangwe, thanked the Minister for recognizing CoVAB’s strategic role and reaffirmed Makerere’s commitment to advancing veterinary science and innovation for Uganda’s prosperity.
Veterinary & Biosecurity
Parliamentary Committee on Science, Technology and Innovation Reviews Uganda’s Emerging Science Ventures
By Jacinta Nakaye
Uganda’s drive to strengthen science, technology and innovation took center stage as the Parliamentary Committee on Science, Technology and Innovation toured Makerere University’s Centre for Biosecurity and Biomolecular Technology (CeBIOTECH). The centre is hosted at the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB). The visit aimed to assess the progress of ventures supported under the Science, Technology and Innovation–Office of the President (STI-OP).
The visit brought legislators, scientists, and innovators together around a shared question: How can Uganda turn investments in scientific research into practical technologies, enterprises, and solutions that respond to national development challenges?
At CeBIOTECH, the Committee was taken through a portfolio of emerging science ventures, including Central Laboratory Animal Research Facility, which focuses on providing lab animal services, pre-clinical trial support, and specialized training to accelerate biosecurity and health solutions; RePROVaD, which focuses on designing and manufacturing recombinant proteins and subunit vaccines for emerging infectious diseases such as COVID-19 and Mpox; the Anti-Tick Vaccine venture focused on addressing the challenge of ticks and tick-borne diseases; and BIOMARKER focused on developing Antibody-based diagnostics.
The delegation also toured laboratories within the Centre where research, product development and other activities supporting the ventures are undertaken.
The engagement offered the Committee a first-hand view of the scientific infrastructure, expertise and processes underpinning Uganda’s efforts to move research beyond academic discovery and towards innovation, enterprise development and eventual application.
Where science meets national priorities
For years, Uganda has invested in research and generated scientific knowledge across universities and research institutions. However, converting that knowledge into products and services that reach communities and markets remains one of the country’s most important innovation challenges. The ventures showcased at CeBIOTECH represent an attempt to bridge this gap.
Although they operate in different areas, the ventures share a common pathway using scientific research and technological expertise to develop solutions with potential to address challenges facing Ugandans while contributing to economic growth.
The Parliamentary Science Committee’s visit consequently provided more than an opportunity to observe ongoing research. It created a platform for legislators to interact with the scientists behind the innovations and gain insight into the journey from research concept to a potentially viable product or enterprise.
That journey can involve years of research, laboratory experimentation, testing, validation, regulatory requirements, intellectual property protection, investment, and commercialisation.
A diverse portfolio of innovation
The diversity of ventures at CeBIOTECH reflects the broad scope of Uganda’s science and innovation agenda.
The CLARF, REPROVaD, and BIOMARKER ventures demonstrate the range of scientific work being pursued. At the same time, the Anti-Tick Vaccine Venture highlights efforts to address one of the persistent challenges affecting livestock production.
Rather than viewing the ventures as isolated projects, the visit highlighted the importance of building an ecosystem in which scientific discoveries can be nurtured into sustainable enterprises.
Such an ecosystem requires more than laboratory facilities. It depends on skilled human resources, research financing, modern infrastructure, regulatory support, partnerships, intellectual property management, manufacturing capacity, and market access.
Taking the fight against ticks beyond conventional control
One of the ventures presented to the Committee was the Tick Control Innovations Initiative Ltd.’s Anti-Tick Vaccine Venture, which is developing a vaccine aimed at controlling ticks and reducing the burden of tick-borne diseases in cattle.
Ticks and tick-borne diseases continue to present significant challenges to livestock production, affecting animal health and productivity and placing additional costs on farmers.
The development of an anti-tick vaccine represents an innovative approach to complement conventional tick-control measures and potentially provide farmers with an additional tool for managing the problem.
The inclusion of the venture among the STI-OP innovations showcased to Parliament demonstrates how scientific research can be directed towards challenges with direct implications for agriculture, livestock production and rural livelihoods.
For Uganda, the significance of such innovations lies not only in the scientific breakthrough itself, but also in the possibility of developing locally generated technologies that can eventually reach farmers and contribute to a more productive livestock sector.
The laboratories behind the innovations
A significant part of the Committee’s programme was the tour of CeBIOTECH’s laboratories. The tour offered members an opportunity to see the facilities where scientific investigations and activities supporting the various ventures are undertaken.
Behind every innovation that eventually reaches the market is a substantial amount of work that is rarely visible to the public: laboratory experiments, sample analysis, quality control, testing, documentation, and validation.
The laboratory visits therefore helped demonstrate that successful innovation requires sustained investment in scientific infrastructure and the people who operate it. For Uganda’s science ventures to mature into viable enterprises, maintaining and strengthening such infrastructure will remain critical.
Parliament and the science agenda
The engagement also highlighted the important role Parliament can play in creating an environment in which scientific innovations can thrive.
While researchers generate knowledge and innovators develop technologies, policy and public investment can determine whether promising innovations receive the support needed to progress.
The Parliamentary Science Committee’s interaction with the ventures therefore provided an opportunity to understand the realities of research and innovation. Such an engagement strengthened the connection between policymakers and scientists, ensuring that decisions concerning science, technology and innovation are informed by the practical experiences of those working within the sector.
A step towards an innovation-driven Uganda
The Parliamentary Committee on Science, Technology, and Innovation’s visit to CeBIOTECH comes at a time when Uganda continues to position science, technology, and innovation as central to national transformation. The ventures visited provide a glimpse into what this ambition can look like in practice; scientists working on locally relevant challenges, laboratories supporting research and development, and emerging enterprises seeking to convert scientific knowledge into usable solutions.
The visit also underscored the importance of sustained collaboration among government, Parliament, universities, research institutions, private-sector players and investors. For the innovators at CeBIOTECH, the engagement provided an opportunity to demonstrate progress, highlight the potential of their work and draw attention to the support required to move their innovations to the next level. For Parliament, it offered a closer look at the people, facilities, and scientific processes behind Uganda’s emerging innovation landscape.
Ultimately, the story unfolding at CeBIOTECH is not simply about laboratories or individual ventures. It is about Uganda’s capacity to generate its own solutions, build enterprises around scientific knowledge, and turn research investment into tangible national value.
As the country pursues a more knowledge-driven economy, the progress of ventures such as CLARF, SUBUNIT, the Anti-Vaccine Venture, RePROVaD, and BIOMARKER will be an important measure of how effectively Uganda can move from research to innovation, from innovation to enterprise, and from enterprise to impact.
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