Veterinary & Biosecurity
An Interdisciplinary approach addressing Ticks and Tick-borne Diseases of cattle in Uganda
Published
3 years agoon
By
Mak Editor
By Joseph Odoi
Globally, Ticks are the most important vectors of disease-causing pathogens in domestic and wild animals and tick-borne diseases (TBDs) are a major threat to both cattle and human health. Understanding the complex interactions within the microbiome is of great importance for understanding how tick-borne pathogens spread and cause disease.
Inspired by the need to generate evidence to inform policy around Tick borne Diseases, a team of researchers from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden, Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, conducted a study to assess diversity of ticks and their Tick Borne Diseases (TBDs) in Uganda from 2017 to 2021.
The researchers organised a dissemination of the project results workshop to stakeholders from various sectors on 27th February, 2023 held at the Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University.
Associate Professor Lawrence Mugisha, Co-principal investigator explained that the purpose of the workshop was to share the results of the different research outputs and discuss various ways to re-package the results for different target audiences and to influence policies for tick control strategies in Uganda.

Having set the scene for the workshop, Associate Professor Maja Malmberg, Principal investigator from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden provided a virtual overview of the Project tilted; Ticks and Tick Borne Diseases (TBDs) in Africa. She noted that the overall purpose of the project was to improve cattle health through increased understanding of the microbial community in cattle and ticks, by investigation of the microbial composition (microbiota) of ticks and how this affects transmission and disease development in cattle in Uganda. As part of the study, she noted that the research team were able to generate new knowledge on diversity of tick species, new viruses and highlighted public health implications of the findings. The project had a capacity building component through supporting masters and PhD students and several technical workshop during the project period.

Various presentations of the results from different studies under the project were made by the project investigators and the PhD student Dr. Steven Balinadi who successfully graduated in 2022.
Below are brief project results from the presentations made at the Workshop;
- A total of 15 different tick species were identified in the five study districts of Kasese, Hoima, Soroti, Gulu and Moroto representing different ecological zones. They also reported high tick burden on cattle from all the study districts. They found out the tick species R. appendiculatus (the brown ear tick), the vector for the causative agent for East Coast Fever (“Amashuwo”, “Amakebe”) was most common tick on cattle in all districts (51.79%) followed by A. variegatum (14.33%) and R. evertsi (8.23%) and continue to dominate tick distribution in Uganda. The team also found ticks that were not known to be in Uganda including Rhipicephalus afranicus that was recently described in South Africa and Rhipicephalus microplus, expanding its geographical zones found ion cattle in Gulu and Soroti districts.
- The team further identified 8 viruses from the blood of cattle suspected to be transmitted by ticks and mosquitoes belonging to 4 viral families (Flaviviridae, Peribunyaviridae, Reoviridae and Rhabdoviridae) and 6 genera (Hepacivirus, Pestivirus, Orthobunyavirus, Coltivirus, Dinovernavirus and Ephemerovirus) among 175 studied cattle. Four of the viruses were new and were tentatively named Zikole virus (Family: Flaviviridae), Zeboroti virus (Family: Reoviridae), Zebtine virus (Family: Rhabdoviridae) and Kokolu virus (Family:Rhabdoviridae). This contributes to the body of the new knowledge in the field of virology. However, they were quick to mention the public implications of all viruses and new viruses remains to be understood through more studies.
- Part of the research assessed cattle exposure to Crimean Congo Haemorrhagic Fever (CCHF) Virus a zoonotic disease of public health importance transmitted by ticks. The study found that 74% (500) of the studied cattle from five districts were exposed to the virus. This raises a big concern a potential source of infections to humans. This concern is verified by the results of investigating 32 CCHF confirmed human cases of the recorded outbreaks between 2013 and 2019. Of the 32 hospitalised human CCHF cases, 32% of them died. Most cases presented with fever (93.8%), followed by hemorrhage (81.3%), headache (78.1%), fatigue (68.8%), vomiting (68.8%) and myalgia (65.6%) and other symptoms. The researchers were able to characterise the CCHF viruses circulating in Uganda, a break through that can inform vaccine and diagnostic tool development.
- Further, looking at the ticks themselves using advanced technologies, ticks were found to carry several viruses most of the unknown and new. The team has at least found 20 new viruses in the ticks and the team will be conducting further studies to understand the implications of the so many viruses in relation to animal and human health.
The team presented potential Public Health Implications of their study results as:
• High diversity and burden of ticks infesting cattle in Uganda has potential for a high pathogen load
• Evidence for range expansion of some tick species; risk for disease emergence in naïve animal and human populations around the country
• Cattle in Uganda are harbouring numerous viruses including novel ones
• CCHF is widespread in Uganda, including where human cases have not been detected. And its endemicity does not overlap with the spatial distribution of Hyalomma ticks
Participants of the stakeholder’s dissemination workshop discussed the results and provided feedback. Out of the discussion, it was generally agreed and proposed that deliberate actions need to be undertaken if we are to address the current challenges posed by ticks and their tick-borne diseases. Participants emphasised the following areas that require immediate attention;
- The need for improved surveillance and diagnostic tools for emerging viruses in animals to prevent their transmission to humans.
- The need for the Government investment in advanced technologies and equipment for improved surveillance, detection, and rapid response to any emerging virus outbreak from ticks and their pathogens.
- There is need to understand the cultural and social context: Therefore, any policy or intervention aimed at preventing disease transmission should take into account the cultural and social practices of the communities involved.
- The government should engage with local communities, listen to their concerns, and incorporate their knowledge and perspectives in developing disease control policies.
- The government should prioritize research and development of strategies to control ticks and prevent tick-borne diseases in both humans and animals. This includes conducting awareness campaigns, developing policies, and providing resources to prevent tick infestation and tick-borne diseases.
- Employ One Health approach: that considers the interactions between human, animal, and environmental health.
- More funding and support for tick-borne disease research and control programs in Uganda and other high-risk areas.
- Integration of livestock and human health surveillance and control measures to prevent the transmission of tick-borne diseases.
- Development of community-based tick control strategies that incorporate local knowledge and practices to increase their relevance and effectiveness.
- Collaboration between government agencies, researchers, and communities to implement effective tick-borne disease control strategies.
In his remarks at the engagement, Dr. Kenneth Mugabi, a Senior Veterinary Officer at Ministry of Agriculture, Animal Industry and Fisheries congratulated the team of researchers for undertaking the value based research adding that it will help inform policy to address ticks and tick borne diseases in the country. He equally noted the urgent need for more innovation to discover and develop vaccines, therapeutics and diagnostics options to respond to the increasing challenges of ticks and tick-borne diseases. Additionally he equally thanked the study funders for partnering with Makerere University to undertake the study.
Dr. Ekwaro Obuku from Makerere University College of Health Sciences in his emphasized the importance of researchers tailoring research in a way that it speaks to policy makers adding that researchers should use all avenue to influence policy initiatives for public good. He equally proposed for the need for researchers to have a data bank around Ticks and Tick-Borne Diseases.

The stakeholders’ workshop attracted over 70 participants ranging from government officials, academia, media, farmers and one- health officials among others.
Key issues discussed by participants include; Policy brief to address Tick and Tick-Borne diseases, Development of community-based tick control strategies that incorporate local knowledge and practices,one-health approach in addressing ticks and Tick-Borne diseases ,Importance of engagement with local communities affected by ticks and Tick-Borne ,the need for effective communication by researchers to influence policy, need to develop diagnostic tools and model based surveillance for early detection and early warning about Vector borne diseases among others
PROJECT TEAM
Principal investigator: Dr. Maja Malmberg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Co-PI in Uganda: Assoc. Professor Lawrence Mugisha – Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda and Ecohealth Research Group, Conservation & Ecosystem Health Alliance, Uganda
PhD student: Mr. Stephen Balinandi – Uganda Virus Research Institute, Uganda and Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda
Professor Erik Bongcam Rudloff – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Dr. Erika Chenais – National Veterinary Institute, Sweden
Assoc. Professor Klara Fischer – Swedish University of Agricultural Sciences, Department of Rural and Urban Development, Sweden
Dr. Lidia Chitimia-Dobler – Bundeswehr Institute of Microbiology and University of Hohenheim, Department of Parasitology, Germany
Dr. John Pettersson – Uppsala University, Department of Medical Biochemistry and Microbiology, Sweden
Dr. Juliette Hayer – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Professor Mikael Berg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Dr. Giulio Grandi – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Assoc. Professor Ingrid Hansson – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
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Veterinary & Biosecurity
Makerere Centre for Biosecurity and Global Health partner with VIQAP Consultancy Services and Stakeholders to Strengthen Biorisk Management Capacity among Laboratory Technologists
Published
2 weeks agoon
October 27, 2025
From 20th to 22nd October 2025, the Centre for Biosecurity and Global Health (CeBIGH) and the Department of Biosecurity, Ecosystems and Veterinary Public Health (BEP) at COVAB, Makerere University, in collaboration with VIQAP Consultancy Services, the Uganda Medical Laboratory Technologists Association (UMLTA), the Biosafety and Biosecurity Association of Uganda (BBAU), and the Uganda National Health Laboratories and Diagnostic Services, conducted a three-day Biorisk Management (Biosafety and Biosecurity) training which happened in the CeBIGH Conference room.
The training was part of an ongoing campaign to provide Continuous Professional Development (CPD) for laboratory professionals working across various sectors—including human health, animal health, environmental, biocontainment, and research laboratories. Participants included government and private laboratory technologists, graduate students of MSc Global Biosecurity and Infectious Disease Management, Clinical Epidemiology, Biomedical Laboratory Technology, as well as early-career biomedical scientists.

Building Competence in Biorisk Management
The Facilitation of the three-day training was led by Mr. JohnBaptist Galiwango, a certified Biorisk Management Professional by the International Federation of Biosafety Associations (IFBA) and Research Assistant in the Department of Biosecurity, Ecosystems and Veterinary Public Health (BEP), COVAB.

Participants were equipped with both theoretical and practical knowledge in key areas such as:
Biosafety and biosecurity principles and practices, Biorisk Management International standards and frameworks (ISO 35001, ISO 15189, ISO 15190, BWC, UNSCR, Cartagena Protocol), Risk management and the AMP model (Assessment, Mitigation, Performance Evaluation), Laboratory design, operations, and biological waste management, Introduction to Cyberbiosecurity and Dual-Use Research of Concern (DURC) and Introduction to Emerging technologies and responsible life sciences research.


Mr. Galiwango emphasized the need for enhanced collaboration among public and private laboratory stakeholders to strengthen Uganda’s preparedness for potential emerging and re-emerging Biothreats and “Disease X.” He highlighted that a resilient laboratory system, supported by competent and well-trained personnel, is crucial in the era of rapid technological advancement. He also noted that over 200 professionals expressed interest in participating, but only a limited number could be accommodated due to resource constraints—underscoring the urgent need for more such capacity-building programs in the future.

Stakeholders’ Reflections and Commitments
Ms. Viola Nakidde, Managing Director of VIQAP Consultancy Services, expressed her appreciation to Makerere CeBIGH for hosting the training and for its continued commitment to professional development in the laboratory field. She reaffirmed VIQAP’s dedication to partnering with academic and professional institutions to close knowledge gaps among laboratory professionals through other CPD programs such as Internal Auditing, Laboratory Leadership and Management training and ISO Standards Implementation and support for laboratory accreditation processes.


The training was officially opened by Prof. Clovice Kankya, Head of the Department of Biosecurity, Ecosystems and Veterinary Public Health , who commended the organizing team led by Mr. Galiwango and Ms. Nakidde. He encouraged participants to apply the knowledge gained for both personal and institutional growth and to seek further learning opportunities in biosafety and biosecurity.


Delivering the keynote address, Mr. Joseph Nkodyo, National Coordinator for Biosafety and Biosecurity Programs at the Ministry of Health, pledged continued government support for private sector partners such as VIQAP Consultancy to strengthen biosafety and biosecurity systems across Uganda’s laboratories. He urged participants to apply their new skills in daily operations and to engage in research advancing biosafety and biosecurity in Uganda.

Figure 9: Some of the participants pose for a Photo with Mr Joseph Nkodyo (In the Middle)- The National Coordinator of Biosafety and Biosecurity programs from Ministry of Health.

Closing Ceremony
The closing ceremony and award of certificate was presided over by COVAB’s Prof. Lawrence Mugisha, who doubles as the Chairperson of the National Biosafety Committee under the Uganda National Council for Science and Technology (UNCST). He applauded the initiative, noting that CeBIGH was the ideal venue for such technical trainings.


Figure 12: Prof Lawrence Mugisha- the Chairperson of the National Biosafety Committee awarding Certificate to one of the active participants during the closure of the activity.

Prof. Mugisha underscored the importance of biosafety and biosecurity in the era of emerging technologies such as Artificial Intelligence (AI). He urged participants to deepen their understanding of Cyberbiosecurity, Dual-Use Research of Concern (DURC), and Gain-of-Function (GoF) Research, emphasizing responsible conduct in life sciences as a cornerstone for global health security.
Participant Feedback
Participants expressed deep gratitude for the opportunity, describing the training as a transformative experience that enhanced their professional competence. Many participants appreciated the practical and interactive approach of the facilitators and called for more frequent and sustained training programs to reach a broader group of professionals across Uganda.


Veterinary & Biosecurity
Tracking Trails Project Launched at Makerere University to Study Free-Roaming Dogs and Disease Spread across Five Nations
Published
3 weeks agoon
October 20, 2025In a groundbreaking advancement for zoonotic disease research, Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) inaugurated the Tracking Trails project, an ambitious, transnational research initiative that aims to expose the spatiotemporal dynamics of free-roaming dogs and their epidemiological implications, particularly concerning rabies.
This endeavor brings together expertise from Uganda, Chad, India, Indonesia, and Switzerland, exemplifying an ideal One Health model. It integrates epidemiology, ecology, veterinary medicine, genomics, and socio-cultural anthropology, forging a transdisciplinary approach to health that is as inclusive as it is innovative.
The project under the department of Biosecurity, Ecosystems and Veterinary Public Health at CoVAB was officially launched at Fairway Hotel in in Kampala on October 16th 2025, at a ceremony attended by a consortium of national and international collaborators.

Dr. Salome Dürr of the University of Bern, the principal investigator, underscored the imperative of comprehending canine mobility not solely through the prism of rabies, but as a broader vector of zoonotic pathogen transmission. “Our inquiry transcends mere rabies surveillance, we intend to interrogate the health ramifications of canine movement,” she said.
Uganda as the Initial Epicenter
Uganda has been strategically designated as the inaugural locus for implementation, owing to its heterogeneous demographic fabric, divided into urban and rural ecosystems, alongside its ongoing national rabies eradication agenda. Research operations will span five districts of Kyegegwa, Masaka, Arua, Soroti, and Kampala, each offering varied ecological and socio-cultural matrices.
Dr. Terence Odoch, the Co – Principal Investigator from CoVAB Makerere University, emphasized the twofold imperative of generating actionable scientific evidence while concurrently cultivating academic capacity through the active inclusion of postgraduate cohorts.

He said what distinguishes the Tracking Trails project is its integrative methodological representation that includes GPS telemetry, behavioral ecology, socio-cultural ethnography, and genomic analysis converge to address critical interrogatives, he said while giving a brief about the project. Why do dogs roam? In what ways are they embedded within human ecologies? Which movement vectors potentiate pathogen propagation? Interventions, he noted, must be established upon the understanding of these dynamics, rather than simplistic vaccination paradigms.
Contextual Complexity across Continents

During the launch, the different implementing countries made brief report about the status of their intended interventions and the prevailing circumstances. It was reported that in Chad, nomadic pastoralism renders canine mobility both indispensable and problematic. Professor Fayiz Abakar emphasized that prior vaccination efforts in N’Djamena achieved epidemiologically significant coverage only when rendered cost-free, underscoring the primacy of accessibility and public engagement.
For India, one of the implementing countries, it was reported that this was a home to an estimated 60 million canines, struggling with a paradoxical cultural disposition that is also spiritual in nature coupled with neglect and abandonment. Dr. Harish Tiwari delineated contrasting rural-urban movement ecologies, revealing expanded urban ranges and increased aggression post-COVID.

For the case of Indonesia, the situation of free roaming dogs was no any better given the socio-religiously complex set up and the endemic rabies in 26 provinces. Dr. Ewaldus Wera described distinctive behavioral adaptations in rural versus urban dogs across Flores, Lombok, and West Timor. Underscoring logistical impediments to surveillance in topographically inaccessible locales.
Rabies as a Persistent Global Threat
During the launch, officiated by CoVAB’s Deputy Principal Prof. James Acai Okwee on behalf of the Vice Chancellor, Prof. Barnabas Nawangwe , it was explained that rabies continues to pose a formidable public health threat, remaining a virulent zoonosis with a near-100% case fatality rate once clinical symptoms appear , despite being entirely preventable through timely prophylaxis.

Dr. Alfred Wejuli of Uganda’s Ministry of Health emphasized the urgent need for intersectoral collaboration under the One Health framework. He underscored that coordinated governance across human, animal, and environmental health sectors is indispensable for sustained disease mitigation and effective rabies control.
By equipping free-roaming dogs with GPS collars, researchers will gain real-time insights into canine movement patterns, enabling the mapping of trajectories, analysis of pack dynamics, home range variability, and interactions with human environments.
Academic and Institutional Capacity Building
Beyond empirical inquiry, the initiative is an incubator for emerging scholars. Makerere University and its partner institutions have embedded postgraduate training into the project’s architecture, equipping students with competencies in cross-disciplinary fieldwork, laboratory diagnostics, and community-based research.
Global Solidarity and Forward Trajectory

Notwithstanding anticipated challenges ranging from logistical constraints in remote terrains to sociocultural sensitivities, the Tracking Trails project offers an unprecedented confluence of innovation, collaboration, and public health utility. As it scales across Africa and Asia, it aspires to generate an empirically grounded, culturally attuned, and ethically informed blueprint for rabies control and canine population management. Dr. Dürr encapsulated the initiative’s ethos: “Rabies transcends borders. Dog mobility defies administrative frontiers. To safeguard both human and animal health, a synergistic, global, and interdisciplinary response is imperative.”

Veterinary & Biosecurity
Sekajja Agro Farms Ltd Seeks Graduate Trainee Partnership with CoVAB
Published
2 months agoon
September 26, 2025
Sekajja Agro Farms Ltd (SAF), a fully integrated poultry enterprise located in Buyuki Nama Sub-County, Mukono District, has initiated strategic discussions with Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) to establish a Graduate Trainee partnership. This collaboration is designed to bridge the persistent gap between academic instruction and practical industry experience by offering final-year students and recent graduates immersive training across the entire poultry value chain.
At a meeting held at CoVAB, the SAF team, led by Dr. Abu Mayanja, the Chief Operations Officer SAF, and the staff of the Department of Livestock and Industry Resources (LIR), a range of operations where the students would benefit were explained, ranging from feed mill production and hatchery management to broiler farming, outgrower coordination, and abattoir services, providing a rich environment for experiential learning. Dr. Abu said the initiative will not only enhance graduate employability but also foster innovation and research, and build technical capacity in Uganda’s poultry sector, while promoting knowledge exchange and entrepreneurial thinking among young professionals. Dr. Mayanja highlighted the significant human resource gap in Uganda’s poultry industry, noting that most workers acquire skills informally on the job. To address this challenge, the partnership will offer final-year students and recent graduates a six-month comprehensive training program, combining mentorship with hands-on experience across SAF’s integrated poultry operations from feed production and hatchery management to broiler farming and processing.

Dr. Sylvia Nalubwama, along with other CoVAB staff, emphasized the strategic importance of the proposed Graduate Trainee partnership with Sekajja Agro Farms Ltd (SAF). The team highlighted that the initiative aligns well with Makerere University’s broader mission to provide education that meets societal needs, especially through practical, skills-based training. The two parties agreed to formalize the partnership following the established process, starting at the departmental level through the School of Veterinary Medicine and Animal Resources (SVAR), and concluding with approval of the Memorandum of Understanding by University Management. They also agreed that, due to the urgent workforce gaps in the poultry industry, they would begin immediate engagement and move forward with preliminary activities, including reaching out to interested students and planning the program, even while formalities are still being finalized.
Among some of the terms of the engagement is providing student facilitation, including rent, internet access, and meals, while emphasizing the importance of attitude, adaptability, and willingness to learn. Students will be selected through a merit-based application and interview process. The meeting also spoke of the need for collaboration with BTVET institutions, certification for trainees, and aligning academic programs with industry expectations.

Representatives of the final-year students in attendance expressed keen interest in the Graduate Trainee program and raised pertinent questions regarding remuneration and post-training employment opportunities. In response, representatives from Sekajja Agro Farms Ltd (SAF) acknowledged the importance of financial incentives but emphasized that the true value of the program lies in the unique exposure it offers to the commercial and operational aspects of poultry production. They assured students that the six-month training module is designed to equip them with critical skills, industry insights, and entrepreneurial competencies that are essential for driving growth and innovation within Uganda’s poultry sector.
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