Veterinary & Biosecurity
An Interdisciplinary approach addressing Ticks and Tick-borne Diseases of cattle in Uganda
Published
3 years agoon
By
Mak Editor
By Joseph Odoi
Globally, Ticks are the most important vectors of disease-causing pathogens in domestic and wild animals and tick-borne diseases (TBDs) are a major threat to both cattle and human health. Understanding the complex interactions within the microbiome is of great importance for understanding how tick-borne pathogens spread and cause disease.
Inspired by the need to generate evidence to inform policy around Tick borne Diseases, a team of researchers from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden, Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, conducted a study to assess diversity of ticks and their Tick Borne Diseases (TBDs) in Uganda from 2017 to 2021.
The researchers organised a dissemination of the project results workshop to stakeholders from various sectors on 27th February, 2023 held at the Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University.
Associate Professor Lawrence Mugisha, Co-principal investigator explained that the purpose of the workshop was to share the results of the different research outputs and discuss various ways to re-package the results for different target audiences and to influence policies for tick control strategies in Uganda.

Having set the scene for the workshop, Associate Professor Maja Malmberg, Principal investigator from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden provided a virtual overview of the Project tilted; Ticks and Tick Borne Diseases (TBDs) in Africa. She noted that the overall purpose of the project was to improve cattle health through increased understanding of the microbial community in cattle and ticks, by investigation of the microbial composition (microbiota) of ticks and how this affects transmission and disease development in cattle in Uganda. As part of the study, she noted that the research team were able to generate new knowledge on diversity of tick species, new viruses and highlighted public health implications of the findings. The project had a capacity building component through supporting masters and PhD students and several technical workshop during the project period.

Various presentations of the results from different studies under the project were made by the project investigators and the PhD student Dr. Steven Balinadi who successfully graduated in 2022.
Below are brief project results from the presentations made at the Workshop;
- A total of 15 different tick species were identified in the five study districts of Kasese, Hoima, Soroti, Gulu and Moroto representing different ecological zones. They also reported high tick burden on cattle from all the study districts. They found out the tick species R. appendiculatus (the brown ear tick), the vector for the causative agent for East Coast Fever (“Amashuwo”, “Amakebe”) was most common tick on cattle in all districts (51.79%) followed by A. variegatum (14.33%) and R. evertsi (8.23%) and continue to dominate tick distribution in Uganda. The team also found ticks that were not known to be in Uganda including Rhipicephalus afranicus that was recently described in South Africa and Rhipicephalus microplus, expanding its geographical zones found ion cattle in Gulu and Soroti districts.
- The team further identified 8 viruses from the blood of cattle suspected to be transmitted by ticks and mosquitoes belonging to 4 viral families (Flaviviridae, Peribunyaviridae, Reoviridae and Rhabdoviridae) and 6 genera (Hepacivirus, Pestivirus, Orthobunyavirus, Coltivirus, Dinovernavirus and Ephemerovirus) among 175 studied cattle. Four of the viruses were new and were tentatively named Zikole virus (Family: Flaviviridae), Zeboroti virus (Family: Reoviridae), Zebtine virus (Family: Rhabdoviridae) and Kokolu virus (Family:Rhabdoviridae). This contributes to the body of the new knowledge in the field of virology. However, they were quick to mention the public implications of all viruses and new viruses remains to be understood through more studies.
- Part of the research assessed cattle exposure to Crimean Congo Haemorrhagic Fever (CCHF) Virus a zoonotic disease of public health importance transmitted by ticks. The study found that 74% (500) of the studied cattle from five districts were exposed to the virus. This raises a big concern a potential source of infections to humans. This concern is verified by the results of investigating 32 CCHF confirmed human cases of the recorded outbreaks between 2013 and 2019. Of the 32 hospitalised human CCHF cases, 32% of them died. Most cases presented with fever (93.8%), followed by hemorrhage (81.3%), headache (78.1%), fatigue (68.8%), vomiting (68.8%) and myalgia (65.6%) and other symptoms. The researchers were able to characterise the CCHF viruses circulating in Uganda, a break through that can inform vaccine and diagnostic tool development.
- Further, looking at the ticks themselves using advanced technologies, ticks were found to carry several viruses most of the unknown and new. The team has at least found 20 new viruses in the ticks and the team will be conducting further studies to understand the implications of the so many viruses in relation to animal and human health.
The team presented potential Public Health Implications of their study results as:
• High diversity and burden of ticks infesting cattle in Uganda has potential for a high pathogen load
• Evidence for range expansion of some tick species; risk for disease emergence in naïve animal and human populations around the country
• Cattle in Uganda are harbouring numerous viruses including novel ones
• CCHF is widespread in Uganda, including where human cases have not been detected. And its endemicity does not overlap with the spatial distribution of Hyalomma ticks
Participants of the stakeholder’s dissemination workshop discussed the results and provided feedback. Out of the discussion, it was generally agreed and proposed that deliberate actions need to be undertaken if we are to address the current challenges posed by ticks and their tick-borne diseases. Participants emphasised the following areas that require immediate attention;
- The need for improved surveillance and diagnostic tools for emerging viruses in animals to prevent their transmission to humans.
- The need for the Government investment in advanced technologies and equipment for improved surveillance, detection, and rapid response to any emerging virus outbreak from ticks and their pathogens.
- There is need to understand the cultural and social context: Therefore, any policy or intervention aimed at preventing disease transmission should take into account the cultural and social practices of the communities involved.
- The government should engage with local communities, listen to their concerns, and incorporate their knowledge and perspectives in developing disease control policies.
- The government should prioritize research and development of strategies to control ticks and prevent tick-borne diseases in both humans and animals. This includes conducting awareness campaigns, developing policies, and providing resources to prevent tick infestation and tick-borne diseases.
- Employ One Health approach: that considers the interactions between human, animal, and environmental health.
- More funding and support for tick-borne disease research and control programs in Uganda and other high-risk areas.
- Integration of livestock and human health surveillance and control measures to prevent the transmission of tick-borne diseases.
- Development of community-based tick control strategies that incorporate local knowledge and practices to increase their relevance and effectiveness.
- Collaboration between government agencies, researchers, and communities to implement effective tick-borne disease control strategies.
In his remarks at the engagement, Dr. Kenneth Mugabi, a Senior Veterinary Officer at Ministry of Agriculture, Animal Industry and Fisheries congratulated the team of researchers for undertaking the value based research adding that it will help inform policy to address ticks and tick borne diseases in the country. He equally noted the urgent need for more innovation to discover and develop vaccines, therapeutics and diagnostics options to respond to the increasing challenges of ticks and tick-borne diseases. Additionally he equally thanked the study funders for partnering with Makerere University to undertake the study.
Dr. Ekwaro Obuku from Makerere University College of Health Sciences in his emphasized the importance of researchers tailoring research in a way that it speaks to policy makers adding that researchers should use all avenue to influence policy initiatives for public good. He equally proposed for the need for researchers to have a data bank around Ticks and Tick-Borne Diseases.

The stakeholders’ workshop attracted over 70 participants ranging from government officials, academia, media, farmers and one- health officials among others.
Key issues discussed by participants include; Policy brief to address Tick and Tick-Borne diseases, Development of community-based tick control strategies that incorporate local knowledge and practices,one-health approach in addressing ticks and Tick-Borne diseases ,Importance of engagement with local communities affected by ticks and Tick-Borne ,the need for effective communication by researchers to influence policy, need to develop diagnostic tools and model based surveillance for early detection and early warning about Vector borne diseases among others
PROJECT TEAM
Principal investigator: Dr. Maja Malmberg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Co-PI in Uganda: Assoc. Professor Lawrence Mugisha – Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda and Ecohealth Research Group, Conservation & Ecosystem Health Alliance, Uganda
PhD student: Mr. Stephen Balinandi – Uganda Virus Research Institute, Uganda and Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda
Professor Erik Bongcam Rudloff – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Dr. Erika Chenais – National Veterinary Institute, Sweden
Assoc. Professor Klara Fischer – Swedish University of Agricultural Sciences, Department of Rural and Urban Development, Sweden
Dr. Lidia Chitimia-Dobler – Bundeswehr Institute of Microbiology and University of Hohenheim, Department of Parasitology, Germany
Dr. John Pettersson – Uppsala University, Department of Medical Biochemistry and Microbiology, Sweden
Dr. Juliette Hayer – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Professor Mikael Berg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Dr. Giulio Grandi – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Assoc. Professor Ingrid Hansson – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden

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Veterinary & Biosecurity
Sekajja Agro Farms Ltd Seeks Graduate Trainee Partnership with CoVAB
Published
2 weeks agoon
September 26, 2025
Sekajja Agro Farms Ltd (SAF), a fully integrated poultry enterprise located in Buyuki Nama Sub-County, Mukono District, has initiated strategic discussions with Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) to establish a Graduate Trainee partnership. This collaboration is designed to bridge the persistent gap between academic instruction and practical industry experience by offering final-year students and recent graduates immersive training across the entire poultry value chain.
At a meeting held at CoVAB, the SAF team, led by Dr. Abu Mayanja, the Chief Operations Officer SAF, and the staff of the Department of Livestock and Industry Resources (LIR), a range of operations where the students would benefit were explained, ranging from feed mill production and hatchery management to broiler farming, outgrower coordination, and abattoir services, providing a rich environment for experiential learning. Dr. Abu said the initiative will not only enhance graduate employability but also foster innovation and research, and build technical capacity in Uganda’s poultry sector, while promoting knowledge exchange and entrepreneurial thinking among young professionals. Dr. Mayanja highlighted the significant human resource gap in Uganda’s poultry industry, noting that most workers acquire skills informally on the job. To address this challenge, the partnership will offer final-year students and recent graduates a six-month comprehensive training program, combining mentorship with hands-on experience across SAF’s integrated poultry operations from feed production and hatchery management to broiler farming and processing.

Dr. Sylvia Nalubwama, along with other CoVAB staff, emphasized the strategic importance of the proposed Graduate Trainee partnership with Sekajja Agro Farms Ltd (SAF). The team highlighted that the initiative aligns well with Makerere University’s broader mission to provide education that meets societal needs, especially through practical, skills-based training. The two parties agreed to formalize the partnership following the established process, starting at the departmental level through the School of Veterinary Medicine and Animal Resources (SVAR), and concluding with approval of the Memorandum of Understanding by University Management. They also agreed that, due to the urgent workforce gaps in the poultry industry, they would begin immediate engagement and move forward with preliminary activities, including reaching out to interested students and planning the program, even while formalities are still being finalized.
Among some of the terms of the engagement is providing student facilitation, including rent, internet access, and meals, while emphasizing the importance of attitude, adaptability, and willingness to learn. Students will be selected through a merit-based application and interview process. The meeting also spoke of the need for collaboration with BTVET institutions, certification for trainees, and aligning academic programs with industry expectations.

Representatives of the final-year students in attendance expressed keen interest in the Graduate Trainee program and raised pertinent questions regarding remuneration and post-training employment opportunities. In response, representatives from Sekajja Agro Farms Ltd (SAF) acknowledged the importance of financial incentives but emphasized that the true value of the program lies in the unique exposure it offers to the commercial and operational aspects of poultry production. They assured students that the six-month training module is designed to equip them with critical skills, industry insights, and entrepreneurial competencies that are essential for driving growth and innovation within Uganda’s poultry sector.
Veterinary & Biosecurity
CoVAB Prepares Future Educators with One Health Skills to Address Zoonotic and Climate Risks
Published
2 weeks agoon
September 23, 2025
On Monday, 22nd September 2025, the Department of Biosecurity, Ecosystems and Veterinary Public Health (BEP) at the College of Veterinary Medicine, Animal Health and Biosecurity (CoVAB), Makerere University, launched a four-day intensive training program aimed at equipping Uganda’s next generation of educators with foundational knowledge in One Health. This initiative seeks to foster interdisciplinary understanding among future teachers, emphasizing the interconnectedness of human, animal, and environmental health in addressing emerging public health challenges.
The initiative, titled “One Health Training of Uganda’s Next Generation of Teachers,” targets selected third-year education students from Makerere University, Kyambogo University, Uganda Christian University (UCU), and Kabale University, along with newly graduated teachers from across the country. The training is one of the activities of the broader Capacitating One Health in Eastern and Southern Africa (COHESA)project, a regional program spanning 12 countries aimed at strengthening interdisciplinary collaboration and promoting integrated approaches to health education and practice.
Prof. Clovice Kankya, Head of the BEP Department at CoVAB and Principal Investigator of the COHESA project in Uganda, underscored the transformative impact of the training, describing it as a strategic investment in the nation’s future health resilience. He noted that by equipping educators with foundational knowledge in One Health, Uganda is fostering a sustainable network of informed leaders capable of influencing both formal education systems and grassroots communities. These teachers will not only embed One Health principles into their curricula but also serve as local ambassadors and champions for improved sanitation, climate adaptation, and disease prevention within their communities.

“This is more than a training,” Prof. Kankya remarked. “It’s a movement to embed One Health thinking into the social fabric of Uganda, given that educators are trusted voices in society. When they grasp the interconnectedness of human, animal, and environmental health, they become powerful catalysts for behavioral change and community-driven action.”
He emphasized the pivotal role of teachers as agents of change, stressing that One Health, a multidisciplinary approach integrating human, animal, and environmental health, is vital for addressing today’s complex health challenges. Despite its growing global relevance, he observed that the concept of One Health remains largely underrepresented in Uganda’s education and public health sectors. This gap, he argued, makes the involvement of teachers especially critical, as they can serve as catalysts for a multiplier effect, extending the reach and impact of One Health principles across both formal education systems and local communities.

Prof. Clovice Kankya further highlighted that the ripple effect of empowering teachers will extend beyond schools, reaching homes, villages, and regional networks. In doing so, the initiative aims to build a generation of citizens who are not only aware of health risks but are also equipped to respond collaboratively and sustainably.
The trainees, drawn from diverse teaching disciplines, received instruction in key areas such as an introduction to One Health principles, zoonotic diseases and outbreak investigation, risk communication strategies, community engagement, and exit protocols, among others. Facilitators from AFROHUN and CoVAB were carefully selected for their expertise in outbreak response, strategic communication, and community-based education. The curriculum is enriched with social science perspectives to strengthen community entry approaches and promote culturally sensitive messaging, ensuring that participants are well-equipped to engage effectively with local populations.
Veterinary & Biosecurity
CIMTRADZ Founders Convention Reflects on Achievements and Sets a Bold Agenda for Global Biosecurity
Published
3 weeks agoon
September 22, 2025
In a strategic gathering at Makerere University’s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ) held its Founder’s Convention to reflect on its 12-year journey and unveil its ambitious next chapter: the Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA). The event, hosted under the School of Biosecurity, Biotechnical and Biomolecular Sciences (SBLS), brought together scientists, students, and strategic partners from across Uganda and beyond. The convention served as both a retrospective and a launchpad, celebrating CIMTRADZ’s achievements while setting a bold agenda for MAGBBA’s future.

Ms. Brenda Nakazibwe, Team Lead for the Pathogen Economy at the Science, Technology and Innovation (STI) Secretariat, delivered an address on behalf of Hon. Dr. Monica Musenero, Minister of Science, Technology, and Innovation. She commended the brains and effort behind CIMTRADZ for their relentless efforts in implementing research and training programs initially supported under the Presidential Initiative on Science and Technology that set the pace for the numerous achievements realised to-date.
Nakazibwe outlined Uganda’s strategic roadmap for harnessing science and innovation to drive national development. She revealed that since March 2022, the STI Secretariat has operated through eight specialized bureaus focused on mobility, export promotion, and productivity acceleration. “Our mandate is to coordinate the ecosystem,” Nakazibwe emphasized, “bringing together academia, media, and the private sector to ensure science leads us to another level.”
While emphasisng the commitment of continued support to the academia in finding solutions to societal challenges, Nakazibwe also spotlighted Uganda’s prioritized industrial value chains, which include ICT, artificial intelligence, infrastructure innovation, aeronautics, and space science. She stressed that science must be a tool to combat poverty and unemployment, aligning with the goals of National Development Plan III.

Representing Vice Chancellor Prof. Barnabas Nawangwe, Prof. Mukadasi Buyinza praised the university’s growing network of research centers, some of which have attained Level 5 status as centers of excellence. He emphasized that the transition from the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ) to the proposed Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA) signals a strategic shift toward sustainability and broader impact.
“In the face of pandemics and epidemics, the world is counting on scientists,” Prof. Buyinza said. “This is no longer a concern confined to laboratories, but it’s a matter of national survival.”
He called on Uganda’s scientific community to develop a comprehensive national inventory of pathogens, stressing that biosecurity must be a shared responsibility across sectors. He also commended the movement of Makerere’s academic talent into government and private agencies, describing it as a positive extension of the university’s influence.
“We are in the Fourth Industrial Revolution,” he noted, urging researchers to harness their expertise to address pressing health and development challenges. “Collaboration and cooperation are no longer optional but are essential.”
Prof. Buyinza concluded by pledging institutional support for scientific initiatives that translate into tangible products and services, reinforcing Makerere’s role as a driver of innovation and societal transformation.

During the convention Prof. John David Kabasa delivered a powerful message on the future of biosecurity and bioeconomy, calling on scientists to take the lead in safeguarding society against biological threats. Prof. Kabasa emphasized the urgent need to protect both human and animal populations from emerging pathogens. He described biosecurity and bioeconomy as critical pillars for national resilience and global competitiveness.
“We are living in an era of insufficiency,” Prof. Kabasa stated, “where bio threats are no longer distant possibilities but immediate challenges demanding coordinated action.”
He commended Makerere University for its visionary leadership and the platform it has provided to advance scientific research and innovation. He also acknowledged the Government of Uganda for its substantial investments across institutions, which he said have laid the foundation for transformative progress.
Prof. Kabasa stressed the importance of capacity building and value amplification, and called on universities and schools to equip learners with skills that enhance the value of biological assets and foster entrepreneurial thinking.
Prof. Kabasa however, he expressed concern over the persistence of outdated ideologies, weak innovation culture, and limited Pan-African collaboration. To address these gaps, he advocated for a culture of collaboration across higher education, research, and service delivery.
“Scientists hold the key to societal transformation,” he said, urging them to embrace their responsibility and develop solutions to pressing challenges.

Prof. M. Kaneene of Michigan State University delivered an inspiring presentation that underscored Uganda’s growing role in global biosecurity and infectious disease preparedness. Speaking as one of the founding mentors of the Consortium for Integrated Management of Transboundary Diseases and Zoonoses (CIMTRADZ), Prof. Kaneene reflected on the initiative’s journey and its far-reaching impact. He highlighted a Special Issue of a scientific journal featuring four foundational papers that helped catalyze new projects not only in Uganda but across Africa and beyond. “Centers like CEBIGH give CoVAB a unique niche in addressing regional and global biosecurity challenges,” Prof. Kaneene said, emphasizing the importance of research and training in tackling emerging and reemerging infectious diseases.
He urged stakeholders to build on past achievements and expand the center’s influence through targeted programs such as short courses and summer training initiatives. With Uganda poised to take a leadership role, he stressed that biosecurity must remain a national priority.

The Principal of the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Prof. Frank Norbert Mwiine, represented by Prof. Savino Biryomumaisho reflected on the consortium’s decade-long impact. He noted that CIMTRADZ had significantly contributed to the expansion of the former Faculty of Veterinary Medicine, particularly under the School of Biosecurity, Biotechnology, and Laboratory Sciences.
“CIMTRADZ has been instrumental in shaping our infrastructure and academic programs,” Prof. Mwiine said. He highlighted key developments including the central laboratory, animal research facility, biomarker and diagnostic facility, and the Centre for Biosecurity and Global Health. He also pointed to the launch of advanced degree programs,Master’s and PhDs,that have created new opportunities for staff and students to pursue higher education and research excellence.
“These achievements align perfectly with Makerere University’s vision of being a thought leader in knowledge generation for societal transformation,” he added. Prof. Mwiine cited vaccine development as one of the tangible outcomes of the consortium’s work and expressed optimism about the next phase of the initiative, which transitions into the Multisectoral Alliance for Global Biosecurity and Bioeconomy Advancement (MAGBBA).

Dr. Claire Mack Mugasa, Dean of the School of Biotechnical and Laboratory Sciences (SBLS), presented an overview of the school’s mandate in biosecurity, biosafety, and biomedical sciences. “Our laboratories are not just teaching spaces, they are hubs of innovation shared across departments, schools, and colleges,” Dr. Mugasa said. She emphasized the importance of partnerships with sister universities in Uganda and abroad, noting that collaboration is key to building capacity and driving scientific progress.
Following her remarks, Dr. Enoch Matovu, Director of the Centre for Global Health, addressed the urgent need for preparedness in the face of emerging and re-emerging diseases. He cited the 2022 chickenpox outbreak as a wake-up call for the region’s health systems.
“The establishment of this research centre was a strategic response to such threats,” Dr. Matovu said. “Through programs like vaccinology, we are equipping scientists to protect both human and livestock ecosystems.”
He praised the founding team behind the Centre for Biosecurity and Global Health for their vision and dedication, which have propelled CoVAB to the forefront of regional biosecurity efforts.

During the CIMTRADZ Founder’s Convention at Makerere University, participants celebrated a decade of achievements in biosecurity and institutional development at CoVAB. Key milestones included the establishment of a state-of-the-art research center, enhanced international collaborations, staff capacity building, and the launch of advanced academic programs. The event also highlighted cultural and academic exchanges such as summer schools, workshops, and conferences. These accomplishments reflect CoVAB’s strategic growth and its evolving role as a regional leader in biosecurity, now transitioning into the next phase under MAGBBA.
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