Veterinary & Biosecurity
An Interdisciplinary approach addressing Ticks and Tick-borne Diseases of cattle in Uganda
By Joseph Odoi
Globally, Ticks are the most important vectors of disease-causing pathogens in domestic and wild animals and tick-borne diseases (TBDs) are a major threat to both cattle and human health. Understanding the complex interactions within the microbiome is of great importance for understanding how tick-borne pathogens spread and cause disease.
Inspired by the need to generate evidence to inform policy around Tick borne Diseases, a team of researchers from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden, Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, conducted a study to assess diversity of ticks and their Tick Borne Diseases (TBDs) in Uganda from 2017 to 2021.
The researchers organised a dissemination of the project results workshop to stakeholders from various sectors on 27th February, 2023 held at the Centre for Biosecurity and Global Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University.
Associate Professor Lawrence Mugisha, Co-principal investigator explained that the purpose of the workshop was to share the results of the different research outputs and discuss various ways to re-package the results for different target audiences and to influence policies for tick control strategies in Uganda.
Having set the scene for the workshop, Associate Professor Maja Malmberg, Principal investigator from Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden provided a virtual overview of the Project tilted; Ticks and Tick Borne Diseases (TBDs) in Africa. She noted that the overall purpose of the project was to improve cattle health through increased understanding of the microbial community in cattle and ticks, by investigation of the microbial composition (microbiota) of ticks and how this affects transmission and disease development in cattle in Uganda. As part of the study, she noted that the research team were able to generate new knowledge on diversity of tick species, new viruses and highlighted public health implications of the findings. The project had a capacity building component through supporting masters and PhD students and several technical workshop during the project period.
Various presentations of the results from different studies under the project were made by the project investigators and the PhD student Dr. Steven Balinadi who successfully graduated in 2022.
Below are brief project results from the presentations made at the Workshop;
- A total of 15 different tick species were identified in the five study districts of Kasese, Hoima, Soroti, Gulu and Moroto representing different ecological zones. They also reported high tick burden on cattle from all the study districts. They found out the tick species R. appendiculatus (the brown ear tick), the vector for the causative agent for East Coast Fever (“Amashuwo”, “Amakebe”) was most common tick on cattle in all districts (51.79%) followed by A. variegatum (14.33%) and R. evertsi (8.23%) and continue to dominate tick distribution in Uganda. The team also found ticks that were not known to be in Uganda including Rhipicephalus afranicus that was recently described in South Africa and Rhipicephalus microplus, expanding its geographical zones found ion cattle in Gulu and Soroti districts.
- The team further identified 8 viruses from the blood of cattle suspected to be transmitted by ticks and mosquitoes belonging to 4 viral families (Flaviviridae, Peribunyaviridae, Reoviridae and Rhabdoviridae) and 6 genera (Hepacivirus, Pestivirus, Orthobunyavirus, Coltivirus, Dinovernavirus and Ephemerovirus) among 175 studied cattle. Four of the viruses were new and were tentatively named Zikole virus (Family: Flaviviridae), Zeboroti virus (Family: Reoviridae), Zebtine virus (Family: Rhabdoviridae) and Kokolu virus (Family:Rhabdoviridae). This contributes to the body of the new knowledge in the field of virology. However, they were quick to mention the public implications of all viruses and new viruses remains to be understood through more studies.
- Part of the research assessed cattle exposure to Crimean Congo Haemorrhagic Fever (CCHF) Virus a zoonotic disease of public health importance transmitted by ticks. The study found that 74% (500) of the studied cattle from five districts were exposed to the virus. This raises a big concern a potential source of infections to humans. This concern is verified by the results of investigating 32 CCHF confirmed human cases of the recorded outbreaks between 2013 and 2019. Of the 32 hospitalised human CCHF cases, 32% of them died. Most cases presented with fever (93.8%), followed by hemorrhage (81.3%), headache (78.1%), fatigue (68.8%), vomiting (68.8%) and myalgia (65.6%) and other symptoms. The researchers were able to characterise the CCHF viruses circulating in Uganda, a break through that can inform vaccine and diagnostic tool development.
- Further, looking at the ticks themselves using advanced technologies, ticks were found to carry several viruses most of the unknown and new. The team has at least found 20 new viruses in the ticks and the team will be conducting further studies to understand the implications of the so many viruses in relation to animal and human health.
The team presented potential Public Health Implications of their study results as:
• High diversity and burden of ticks infesting cattle in Uganda has potential for a high pathogen load
• Evidence for range expansion of some tick species; risk for disease emergence in naïve animal and human populations around the country
• Cattle in Uganda are harbouring numerous viruses including novel ones
• CCHF is widespread in Uganda, including where human cases have not been detected. And its endemicity does not overlap with the spatial distribution of Hyalomma ticks
Participants of the stakeholder’s dissemination workshop discussed the results and provided feedback. Out of the discussion, it was generally agreed and proposed that deliberate actions need to be undertaken if we are to address the current challenges posed by ticks and their tick-borne diseases. Participants emphasised the following areas that require immediate attention;
- The need for improved surveillance and diagnostic tools for emerging viruses in animals to prevent their transmission to humans.
- The need for the Government investment in advanced technologies and equipment for improved surveillance, detection, and rapid response to any emerging virus outbreak from ticks and their pathogens.
- There is need to understand the cultural and social context: Therefore, any policy or intervention aimed at preventing disease transmission should take into account the cultural and social practices of the communities involved.
- The government should engage with local communities, listen to their concerns, and incorporate their knowledge and perspectives in developing disease control policies.
- The government should prioritize research and development of strategies to control ticks and prevent tick-borne diseases in both humans and animals. This includes conducting awareness campaigns, developing policies, and providing resources to prevent tick infestation and tick-borne diseases.
- Employ One Health approach: that considers the interactions between human, animal, and environmental health.
- More funding and support for tick-borne disease research and control programs in Uganda and other high-risk areas.
- Integration of livestock and human health surveillance and control measures to prevent the transmission of tick-borne diseases.
- Development of community-based tick control strategies that incorporate local knowledge and practices to increase their relevance and effectiveness.
- Collaboration between government agencies, researchers, and communities to implement effective tick-borne disease control strategies.
In his remarks at the engagement, Dr. Kenneth Mugabi, a Senior Veterinary Officer at Ministry of Agriculture, Animal Industry and Fisheries congratulated the team of researchers for undertaking the value based research adding that it will help inform policy to address ticks and tick borne diseases in the country. He equally noted the urgent need for more innovation to discover and develop vaccines, therapeutics and diagnostics options to respond to the increasing challenges of ticks and tick-borne diseases. Additionally he equally thanked the study funders for partnering with Makerere University to undertake the study.
Dr. Ekwaro Obuku from Makerere University College of Health Sciences in his emphasized the importance of researchers tailoring research in a way that it speaks to policy makers adding that researchers should use all avenue to influence policy initiatives for public good. He equally proposed for the need for researchers to have a data bank around Ticks and Tick-Borne Diseases.
The stakeholders’ workshop attracted over 70 participants ranging from government officials, academia, media, farmers and one- health officials among others.
Key issues discussed by participants include; Policy brief to address Tick and Tick-Borne diseases, Development of community-based tick control strategies that incorporate local knowledge and practices,one-health approach in addressing ticks and Tick-Borne diseases ,Importance of engagement with local communities affected by ticks and Tick-Borne ,the need for effective communication by researchers to influence policy, need to develop diagnostic tools and model based surveillance for early detection and early warning about Vector borne diseases among others
PROJECT TEAM
Principal investigator: Dr. Maja Malmberg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Co-PI in Uganda: Assoc. Professor Lawrence Mugisha – Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda and Ecohealth Research Group, Conservation & Ecosystem Health Alliance, Uganda
PhD student: Mr. Stephen Balinandi – Uganda Virus Research Institute, Uganda and Makerere University, College of Veterinary Medicine, Animal Resources and Biosecurity, Uganda
Professor Erik Bongcam Rudloff – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Dr. Erika Chenais – National Veterinary Institute, Sweden
Assoc. Professor Klara Fischer – Swedish University of Agricultural Sciences, Department of Rural and Urban Development, Sweden
Dr. Lidia Chitimia-Dobler – Bundeswehr Institute of Microbiology and University of Hohenheim, Department of Parasitology, Germany
Dr. John Pettersson – Uppsala University, Department of Medical Biochemistry and Microbiology, Sweden
Dr. Juliette Hayer – Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics, Sweden
Professor Mikael Berg – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Dr. Giulio Grandi – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Assoc. Professor Ingrid Hansson – Swedish University of Agricultural Sciences, Biomedical Sciences and Veterinary Public Health, Sweden
Veterinary & Biosecurity
Makerere University and Partners Celebrate INSSPIRE Project Achievements in Evidence-Based Higher Education on Food Systems and Climate Action
By Harriet Musinguzi & Jacinta Nakaye
INSSPIRE, a flagship project housed at the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), has successfully concluded its three-year implementation journey with a final workshop held on Tuesday, 18th November 2025, at the Imperial Royale Hotel. The workshop brought together key stakeholders from leading universities across Europe and Africa to reflect on the project’s achievements, share lessons learned, and explore opportunities for future collaboration.
Over the past three years, the INSSPIRE Project has made significant strides in advancing research, innovation, and capacity-building, particularly in the areas of food systems and climate action. Through its initiatives, the project has contributed to strengthening academic programs and aligning them more closely with societal needs and the evolving job market.
Some of the notable achievements of the INSSPIRE Project include the comprehensive review and enrichment of the curriculum, ensuring that learning is not only academically rigorous but also practically relevant to societal needs and the evolving job market. In addition, the introduction of real-life learning labs has provided students with invaluable hands-on experience, enabling them to engage directly with community challenges and apply their knowledge in practical, impactful ways. The project has also pioneered the use of Collaborative Online International Learning (COIL), linking students with peers from other countries to foster cross-cultural exchange and collaborative problem-solving. This innovative approach has strengthened the connection between academia and society, equipping graduates to become solution-oriented leaders in addressing pressing global issues such as food systems and climate action.
Prof. Barnabas Nawangwe, the Vice Chancellor of Makerere University, was represented at the conference by Prof. Julius Kikoma, Director of Graduate Training. Delivering remarks on behalf of the Vice Chancellor, Prof. Kikoma commended the remarkable achievements realized through the strong partnership of multiple universities under the INSSPIRE initiative. He underscored the conference theme, “Advancing Evidence-Based and Inclusive Education for Food Systems and Climate Action,” as a powerful reflection of the project’s commitment to tackling global challenges through innovation, collaboration, and shared learning.
Prof. Nawangwe noted that the INSSPIRE Project, centered on innovation for sustainability and societal relevance, has successfully brought together universities from the Netherlands, Spain, Slovenia, Kenya, Uganda, Benin, and South Africa. Within this collaborative ecosystem, institutions have reimagined higher education to make it more inclusive, experiential, and responsive to pressing challenges such as food systems transformation and climate change.
Nawangwe noted that this transformation comes at a critical time when Africa faces immense challenges in food security and climate change. Uganda remains highly vulnerable, with floods and other climate shocks severely affecting communities and livelihoods. He emphasized that food systems are under pressure from rapid population growth, unsustainable practices, and environmental degradation, while climate change is already impacting nutrition and resilience. Universities like Makerere must rise to this challenge, he said, and that through initiatives like the INSSPIRE Project, Makerere University joined regional and international partners to generate evidence, influence policy, and drive innovation though solutions generated by students, researchers, and communities.
The Vice Chancellor expressed gratitude to Vrije Universiteit Amsterdam, the project’s lead institution, for fostering collaboration that has strengthened long-term partnerships between Makerere and universities in Europe and Africa. He praised this cooperation as a model of global academic partnership, where learning flows both ways and innovation thrives in diversity. He also thanked Erasmus+, the European Union, RUFORUM, FAO, national agencies, and research institutions for their support. Special recognition was given to CoVAB for providing an enabling environment, and to the dedicated Makerere INSSPIRE team led by Dr. Charles Drago Kato, whose leadership has been central to the project’s success.
Prof. Frank Norbert Mwiine, Principal CoVAB expressed the commitment of the college leadership in moving the INSSPIRE innovations forward, as demonstrated in the innovations in the department of Livestock resources and the continuous development of staff to broaden the teaching of these courses. He said the college would remain part of the network and appreciated INSSPIRE for the capacity-building initiatives for the staff of the college especially in the new pedagogical methodologies like the real-life lab.
Dr. Denyse Snelder from VU Amsterdam gave a broad overview of the project activities they engaged in, including the capacity development on evidence-based and inclusive education, strengthening the university to community collaboration, and inter-university collaborations. She highlighted the key achievements realized, which include sixty lecturers actively engaged, 850 students reached through enriched courses, Five Hundred community stakeholders engaged, establishment of community practice with Eighteen Universities in Africa and Europe under the umbrella, South to South and triangular cooperation.
The INSSPIRE Project aimed to prepare students in higher education for labor market success by equipping them with the knowledge and skills needed to drive food systems transformation and adapt to climate change, thereby contributing to sustainable growth.
Veterinary & Biosecurity
Urban Farming & Climate-Smart Practices: Makerere Researchers Explore Innovations at Kyakuwa Farm
A team of scientists under the collaborative research project “Building Capacity for Innovation and Advancement of Climate Smart Agriculture in East and Southern Africa (CICSA-E&SA)” recently visited Kyakuwa Farm, a model site for urban farming innovations. The visit provided valuable insights into practical climate-smart farming technologies that can strengthen resilience and reduce emissions in urban and peri-urban livestock systems.
The Climate-Smart Agriculture project is led by Makerere University in partnership with the Norwegian University of Life Sciences (Norway), Maseno University (Kenya), LUANAR, and DARS (Malawi), with funding from the Norwegian Agency for International Cooperation and Quality Enhancement in Higher Education (Diku). One of its objectives is to develop a Climate-Smart Agriculture (CSA) Platform to bring together key stakeholders to share experiences, promote proven CSA technologies, and build farmer resilience while minimizing greenhouse gas emissions.
The visit was led by Principal Investigator Dr. Nampanzira Dorothy Kalule from the Department of Livestock and Industrial Resources at the College of Veterinary Medicine, Animal Resources, and Biosecurity (CoVAB), Makerere University. She was joined by other scientists, including Prof. Vincent Muwanika, whose combined expertise enriched the engagement at Kyakuwa Farm. Together, the delegation emphasized Makerere University’s dedication to promoting urban farming and climate-smart agriculture through collaborative learning and knowledge exchange.
While at the farm, the scientists witnessed a number of climate-smart innovations that reinforce the sustainability of the Kyakuwa dairy system. These included silage made from excess sweet potato vines, hay produced from Paspalum grass during compound slashing, and hydroponic fodder cultivated as a nutrient-rich supplement. To address the persistent challenge of flies, the farm applies diatomaceous earth, an organic insecticide, both in the environment and mixed with feed. This integrated approach, they learned, enhanced animal nutrition, improved herd health, and maintained environmental hygiene.
Prof. Jolly M. L. Kabirizi, Executive Director of Kyakuwa Farm and animal research scientist at Valley University of Science and Technology, welcomed the Makerere University team. She showcased her sustainable urban farming model, highlighting dairy production supported by innovative feed, waste management, and climate-smart practices that reduce costs, empower youth, and promote community engagement. The farm places dairy production at its core, integrating innovative feed and waste-management practices that embody climate-smart agriculture. These strategies enhance productivity, optimize resource utilization, and minimize environmental impact, making the farm a replicable model for sustainable urban farming.
According to the scientists, Prof. Kabirizi’s standout innovation is her concept of “turning waste into wealth.” Instead of relying mainly on elephant grass like many dairy farmers, she introduced the use of assorted organic market waste as a sustainable feed source. By training vendors in waste recovery, she incorporates bean pods, sweet potato vines, and pineapple residues into her feeding program. These unconventional resources now form a major part of her dairy system, cutting feed costs, improving sustainability, and reducing organic waste in urban markets.
Prof. Kabirizi complements her waste-to-feed innovations with sustainable feeding technologies that reinforce Kyakuwa Farm’s resilience. The farmer produces silage from surplus sweet potato vines, hay from Paspalum grass during compound slashing, and hydroponic fodder as a nutrient-rich supplement. To tackle the challenge of flies, Kabirizi said she applies diatomaceous earth organically in both the environment and feed. This integrated system boosts animal nutrition, strengthens herd health, and maintains environmental hygiene, showcasing climate-smart agriculture in action.
Kyakuwa Farm highlights a climate-smart use of manure by transforming it into a valuable energy resource. Through solar drying, manure is converted into charcoal briquettes that offer households a cleaner, affordable alternative to firewood. This innovation reduces reliance on traditional fuels, eases pressure on forests, and integrates renewable energy into livestock management, showcasing how circular resource use strengthens sustainability and climate resilience in urban farming. In her closing remarks, after successful deliberations with the scientists, Prof. Kabirizi urged the visiting scientists to champion early retirement planning among farmers, drawing on her own rewarding retirement shaped by community training and mentorship. She has empowered households within and beyond Wakiso District through skills in urban dairy management, climate-smart feeding, and value addition.
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