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Veterinary & Biosecurity

Researchers embark on Capacitating One Health in Eastern and Southern Africa (COHESA) Project in Uganda

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By Joseph Odoi

Makerere University’s College of Veterinary Medicine, Animal Resources and Bio Security (CoVAB), with a consortium of partners, namely the International Livestock Research Institute (ILRI), the French Agricultural Research Centre for International Development (CIRAD) and International Service for the Acquisition of Agri-biotech (ISAAA) have embarked on implementing a new project titled; Capacitating One Health in Eastern and Southern Africa (COHESA) Project, funded by the European Union.

This project aims to generate an inclusive Research & Innovation ecosystem, facilitating rapid uptake, adaption and adoption of solutions to issues that can be dealt with using a One Health approach, with the One Health concept embedded across society in Eastern and Southern Africa (ESA), working for healthy humans, animals and environments.

The project was launched during a stakeholders meeting held on 7th December 2022 at the Biosecurity Centre, Makerere University. The function was graced by Prof. James Okwee Acai, the Deputy Principal of CoVAB, Rose Nakabugo from the Office of the Prime Minister and other government institutions   that include Ministry of Health, Kyambogo University and the National One Health Platform among others.

While officially launching the project, Prof. Clovice Kankya, the Project’s Principal Investigator (PI) for East Africa welcomed the participants to the event. He noted that; the world is facing unprecedented, inter-connected threats to the health of people, animals, and the environment; addressing these threats requires cross-sectoral, systems-wide approaches.

“The One Health concept recognizes the interconnection between people, animals, plants, and the environment.COVID-19 and its origins as a zoonotic pathogen is a particularly pertinent example, but One Health concerns many of the other major threats of our time, such as climate change and disease emergence, antimicrobial resistance, ecosystem destruction with loss of biodiversity and the fragility of food and feed systems.

 In a globalised world, it is imperative that all nations and societies better manage One Health. In this project we look to build One Health capacity in Eastern and Southern Africa” Prof.Kankya explained of the new project

Expected outputs

  • Government entities with OH mandates and OH stakeholders across society capacitated in cross-sectoral collaboration around OH
  • Government entities capacitated in the development of evidence-based OH strategies and policies
  • National secondary, tertiary, and vocational education institutes strengthened in building OH capacity for the next generation workforce
  • Research institutes capacitated in training next generation OH researchers
  • Research institutes capacitated in identification, development, adaption, and delivery of OH solutions (technologies, soft skills and strategic approaches for addressing current challenges)
  • Service providers (public, private) capacitated in identification, adoption and delivery of OH solutions
  • OH related Public-Private Partnerships strengthened in delivery of OH solutions and consultation on OH issues
  • Contribution to emerging understanding on OH, its appropriate use and added value
  • Knowledge and Information on OH research and policies in ESA promoted through project platforms

In his remarks, Professor James Okwee Acai, the Deputy Principal on behalf of the Principal Prof. Norbert Frank Mwiine emphasized the importance multi-sectoral approach and collaboration in One Health adding that capacity building is key in One Health research. He also thanked partners for choosing to work with Makerere University as a trusted partner in One Health research.

Prof. James Okwee Acai, the Deputy Principal of the College of Veterinary Medicine, Animal Resources and Bio-security (CoVAB).
Prof. James Okwee Acai, the Deputy Principal of the College of Veterinary Medicine, Animal Resources and Bio-security (CoVAB).

In her remarks, Rose Nakabugo from the Office of the Prime Minister said, ‘Uganda as a country is faced by zoonotic diseases thus the coming of COHESA will help in addressing these challenges affecting humans, animals and environment.’ She, in a special way, thanked the project team lead for Uganda, Prof. Kankya for taking lead in an initiative that will help in knowledge generation and provide direction for One Health including a curriculum for further education in One Health

Rose Nakabugo from the Office of the Prime Minister reaffirmed government’s commitment in One Health Initiative.
Rose Nakabugo from the Office of the Prime Minister reaffirmed government’s commitment in One Health Initiative.

During this launch, One Health Stakeholders were taken through focus group discussions, interviews with key stakeholders were organized, and the Q & A feedback and evaluations were collected. The focus group session was chaired by Mr. Okello Justine from COVAB

Mr. Justine Okello from CoVAB leading participants through a Q&A session as part of COHESA Project Work.
Mr. Justine Okello from CoVAB leading participants through a Q&A session as part of COHESA Project Work.

Some of the issues highlighted by the participants were relevance of One Health at their workplace, the importance of capacity building in one health, funding challenges around One Health, capacity building, coordination and collaborations around One Health, what should be done to promote One Health and challenges and the future of One Health in 10 years from now.

More about the Project

The COHESA project consortium works with in-country multiplier organizations (mostly One Health research and implementation organizations) to deliver the project to beneficiaries, mainly government, education, research and service providers engaged in One Health.

Duration: December 2021-November 2025  (funded by the European Union)

Project Leads:

Theo Knight-Jones (ILRI), Alexandre Caron (CIRAD); Margaret Karembu (ISAAA)

For more information, visit the project website: https://www.ilri.org/research/projects/capacitating-one-health-eastern-and-southern-africa

Mak Editor

Veterinary & Biosecurity

Alumni of Molecular Biology Honor Prof. George William Lubega for Outstanding Contributions

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Professor George William Lubega. Alumni of molecular biology, College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University honor Prof. George William Lubega, a distinguished teacher whose dedication to nurturing scientists has left an indelible mark on Uganda's scientific community, 28th March 2025, Mestil Hotel, Kampala, Uganda East Africa.

On Friday, March 28th, 2025, alumni of molecular biology gathered at Mestil Hotel in Kampala to honor Prof. George William Lubega, a distinguished teacher whose dedication to nurturing scientists has left an indelible mark on Uganda’s scientific community.

The event, organized by the alumni, celebrated Prof. Lubega’s pivotal role in transforming students into leaders in molecular biology. Dr. Claire Mack Mugasa, Dean of the School of Biosecurity, Biotechnical, and Laboratory Sciences at Makerere University, shared heartfelt recollections of Prof. Lubega’s impact, including his scholarship support and passionate teaching style. Dr. Mugasa noted, “The scientists we have in Uganda are a testimony to his boldness. He has been a father to us in science, and now we are fathers of others.”

Prof. Lubega expressed gratitude for the honor and acknowledged the mentorship he received from his teachers. He also highlighted his groundbreaking contributions, including patented vaccines against trypanosomiasis, and thanked Makerere University for providing an enabling environment for scientific advancement.

The event emphasized the importance of continuing his legacy through initiatives like an association of molecular biologists. The alumni expressed their deep appreciation for Prof. Lubega’s selfless efforts, which have transformed the landscape of science education in Uganda.

This celebration stands as a testament to Prof. Lubega’s lasting influence on his students, colleagues, and the scientific community at large.

Harriet Musinguzi

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Veterinary & Biosecurity

Uganda Advances Bacteriophage Research in Fight against Antimicrobial Resistance

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Researchers and policy makers together with partners from the UK and USA that took part in the symposium. Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity convened symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), March 2025, Hilton Garden Inn, Kampala, East Africa.

Makerere University convened a symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), the event brought together researchers from Makerere University, Kyambogo University, Kampala International University, and Ian Clarke International University, and other players, highlighting a collaborative approach to tackling global and local issues.

Day two of the symposium saw researchers and policy makers together with partners from the UK and USA hold a discourse on the best way forward in the promotion of bacteriophage research and production in the country to support efforts against anti-microbial resistance.

Dr. Jesca Nakavuma, the lead phage researcher from the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), gave the background to the workshop. Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity convened symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), March 2025, Hilton Garden Inn, Kampala, East Africa.
Dr. Jesca Nakavuma, the lead phage researcher from the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), gave the background to the workshop.

Speaking at the event held at Hilton Garden Inn, Dr. Jesca Nakavuma, the lead phage researcher from the College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB), Makerere University, stressed the urgent need for alternative antimicrobial agents due to the rise in drug resistance and limited discovery of new antibiotics. Bacteriophages, natural viruses that target bacteria, she said, were identified as a promising solution to revolutionize disease control, treatment, and food security. She said research in this area was key because humankind was at risk of the impending calamity of life-threatening treatment failure.

Prof. Robert Wamala, represented the VC, Prof. Barnabas Nawangwe. Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity convened symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), March 2025, Hilton Garden Inn, Kampala, East Africa.
Prof. Robert Wamala, represented the VC, Prof. Barnabas Nawangwe.

Prof. Robert Wamala, Makerere University‘s Director for Research, Innovations, and Partnerships, who spoke on behalf of the Vice Chancellor, Prof. Barnabas Nawangwe, underscored the importance of building local capacity in phage research. He noted that such efforts could enhance Uganda’s resilience against AMR and yield homegrown solutions for human, animal, and crop health.

As the world grapples with the growing threat of antimicrobial resistance (AMR), bacteriophage research offers a promising alternative. Phages, which are natural enemies of bacteria, have the potential to revolutionize the approach to treatment, disease control, and food security, he noted.  He said building local expertise in phage application can enhance Uganda’s resilience against AMR and produce sustainable homegrown solutions to health and environmental challenges.

A section of the stakeholders who participated in the discourse listened attentively. Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity convened symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), March 2025, Hilton Garden Inn, Kampala, East Africa.
A section of the stakeholders who participated in the discourse listened attentively.

Prof. Robert Wamala said Makerere University was committed to supporting cutting-edge research and innovation that addresses national and global challenges in line with the university’s role in knowledge generation, technology advancement, and policy influence. The importance of regulatory institutions, he said, cannot be overemphasized in this endeavor, since they enforce compliance, uphold ethical standards, and foster an enabling environment for impactful research and innovation.  He said the engagement presented an opportunity to strengthen collaboration between researchers, institutions, and regulatory bodies to ensure that the outcomes are scientifically sound and are aligned to the national development priorities and global best practices.

Dr. Claire M. Mugasa, the Dean of the School of Biosecurity, Biotechnical and Laboratory Sciences (SBLS), CoVAB reiterated the fact that antimicrobial resistance was on the rise in Uganda and Africa, more than elsewhere in the world. She said it was time now that efforts be intensified in looking for sustainable options to curb the dangerous trends.  She said this cuts across the human and the animals.  She said it was an opportune time for players to come together to find ways of getting the required alternative.  She said by coming together, the different ideas developed individually would in a concerted effort, pulling resources together for a way forward.

Dr. Claire M. Mugasa, the Dean of the School of Biosecurity, Biotechnical and Laboratory Sciences (SBLS) addressed the meeting. Makerere University College of Veterinary Medicine, Animal Resources and Biosecurity convened symposium to explore bacteriophage applications in combating antimicrobial resistance (AMR) and addressing health, agricultural, and environmental challenges. Organized by The Alliance for Phage Research and Development Uganda Ltd (PhageTeam Uganda), March 2025, Hilton Garden Inn, Kampala, East Africa.
Dr. Claire M. Mugasa, the Dean of the School of Biosecurity, Biotechnical and Laboratory Sciences (SBLS) addressed the meeting.

During the discourse, several subjects were addressed, including an introduction to antimicrobial resistance, phage biology, phage application, and lessons learnt from the establishment of a phage research centre in the UK, which was presented by Prof. Martha Clokie from the University of Leicester. This initiative reflects a commitment to fostering innovation, collaboration, and regulatory compliance, positioning Uganda as a leader in sustainable solutions for global challenges.

The symposium was sponsored by Global AMR Innovation Fund (GAMRIF), through a grant to the UK Medicines and Healthcare products Regulatory Agency (MHRA) in partnership with Phages for Global Health.

Harriet Musinguzi

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Veterinary & Biosecurity

First Symposium on Bacteriophage Research & Applications in Uganda Highlights Remarkable Milestones & Future Prospects

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1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.

Bacteriophage research and its applications were the focal point of the 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University‘s College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025. This landmark event showcased Uganda’s strides in harnessing bacteriophages as innovative solutions to antimicrobial resistance (AMR) and other pressing health and agricultural challenges.

Tobi Elaine Nagel, the President of Phages for Global Health (USA), was one of the presenters. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
Tobi Elaine Nagel, the President of Phages for Global Health (USA), was one of the presenters.

Key speakers included Dr. Jesca Nakavuma, CoVAB (Makerere University), who showcased Uganda’s pioneering phage research initiatives and vision. Tobi Elaine Nagel, the President of Phages for Global Health (USA), discussed the global significance of phage research. Prof. Martha Clokie, from the University of Leicester’s Centre for Phage Research (UK), shared insights into the latest advancements in phage therapy. Dr. Robert Blasdel, representing VASALE (Belgium), presented innovative solutions using bacteriophages. Ms. Abigail Riggs, from the Foreign, Commonwealth and Development Office (UK), emphasized international partnerships and policy development.

Prof. Robert Wamala, Director, Directorate of Research, Innovation and Partnerships addressed the participants. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
Prof. Robert Wamala, Director, Directorate of Research, Innovation and Partnerships addressed the participants.

Speaking at the event, Prof. Edward Wamala, Makerere University’s Director of Research, Innovation and Partnerships, who represented the Vice Chancellor Prof. Barnabas Nawangwe at the event, highlighted the critical role of bacteriophage research in addressing the global threat of antimicrobial resistance (AMR). He explained how the misuse and overuse of antibiotics in human health, agriculture, and aquaculture have accelerated the emergence of drug-resistant bacterial strains, rendering standard treatments ineffective. Citing statistics from the World Health Organization, he pointed out that AMR claims over 1.3 million lives annually, a number expected to rise without urgent action. He lamented the stagnation of new antibiotic development due to high research costs and rapid bacterial resistance, making bacteriophage therapy a powerful and promising alternative.

A Section of the stakeholders that participated in the engagement. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
A Section of the stakeholders that participated in the engagement.

Prof. Wamala expressed Makerere University’s commitment to advancing research that addresses critical societal challenges, aligning with its mission of generating transformative knowledge and fostering sustainable development. He emphasized Uganda’s potential to lead in bacteriophage research, driven by multi-disciplinary partnerships and capacity building. He also highlighted ongoing studies into aquaculture-specific bacteriophages at CoVAB as an example of how phage technology can revolutionize sectors like agriculture while addressing AMR. Through such efforts, the university aims to position Uganda as a global leader in innovative solutions to combat antimicrobial resistance and enhance public health.

Dr. Jesca Nakavuma, from the College of Veterinary Medicine, Animal Resources, and Biosecurity. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
Dr. Jesca Nakavuma, from the College of Veterinary Medicine, Animal Resources, and Biosecurity.

Dr. Jesca Nakavuma, widely regarded as the mother of phages in Uganda, delivered a compelling presentation at the Symposium, where she detailed the impressive progress of phage research in Uganda since its inception in 2017. She highlighted Makerere University’s pioneering efforts, starting with a cohort of five undergraduate students, which have since expanded into groundbreaking research addressing challenges in agriculture, clinical health, food safety, and environmental safety. Key achievements include advancements in E. coli and Salmonella detection, tackling avian colibacillosis, and innovations in decontamination methods, underscoring the transformative potential of phage technology in combating antimicrobial resistance and enhancing public health.

The University leadership included Prof. Robert Wamala (R) and Assoc. Prof. James Acai Okwee (C), Deputy Principal CoVAB. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
The University leadership included Prof. Robert Wamala (R) and Assoc. Prof. James Acai Okwee (C), Deputy Principal CoVAB.

The symposium honored collaborative efforts, including the establishment and accomplishments of Phage Team Uganda, which developed a repository of 125 characterized phage isolates and trained over 20 PhDs, MScs, and BSc students. Partnerships with international organizations such as IDRC InnoVet AMR and AU Safe Fish have significantly contributed to advancements in antimicrobial resistance and aquaculture.

The participants were actively involved in the discussions. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
The participants were actively involved in the discussions.

Despite these achievements, Dr. Nakavuma noted challenges such as insufficient facilities for large-scale phage production, regulatory limitations, and financial constraints. She affirmed that despite the challenges, the team remained ambitious, envisioning the creation of a fully equipped Phage Research and Development Center, the commercialization of phage products, and the establishment of policy frameworks to support the use of phages in Uganda.

The Deputy Principal of CoVAB, Prof. James Acai Okwee, warmly welcomed the partners to the conference and acknowledged their invaluable contributions to the college’s research efforts. He emphasized the importance of collaboration in driving innovation and achieving impactful results, highlighting the pivotal role that partnerships play in fostering academic and scientific growth. Prof. Okwee’s remarks set an encouraging tone for the conference, reinforcing the college’s commitment to advancing research initiatives and creating opportunities for shared learning and development.

Part of the audience at the symposium. 1st Symposium on Bacteriophage Research and Applications, convened by Makerere University's College of Veterinary Medicine, Animal Resources and Biosecurity (CoVAB) on Thursday, March 27, 2025, School of Food Technology, Nutrition and Bioengineering Conference Hall, CAES, Kampala Uganda, East Africa.
Part of the audience at the symposium.

The event that attracted the participation of various stakeholders including academia, civil society, and policy makers, concluded with acknowledgments of the efforts of Phage Team Uganda, collaborators, and funders, setting the stage for an exciting future in Uganda’s journey to combat antimicrobial resistance and ensure food and environmental safety.

Harriet Musinguzi

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