Connect with us

Natural Sciences

PAIRWISE Project Engages Mbarara Stakeholders on Antibiotic Resistance

Published

on

Most of the antibiotics used to manage diseases in humans and livestock end up in the environment. Antibiotics (ATBs), Antibiotic Resistant Bacteria (ARB), and Antibiotic Resistance (ARGs) have spread in almost all habitats globally. The Food and Agricultural Organization (FAO), World Health Organization (WHO), and the World Organization for Animal Health (OIE) recognize the problem of Antimicrobial Resistance (AMR), and thus recommend: Prudent use of antimicrobials; and a “One Health Approach” to mitigate the problem. Antimicrobial Resistance (AMR) is a situation where bacteria develop resistance against antibiotics intended to destroy them.

Dr Robinson Odong briefing stakeholders about the project
Dr Robinson Odong briefing stakeholders about the project

Antibiotics in the environment may induce AMR in bacteria, hence the risk of transfer to humans and wildlife. AMR reduces effectiveness of antibiotics, leading to higher costs of treatment, severe illnesses, and deaths. Globally, about 1.2 million people died in 2019 due to complications of AMR; Sub-Saharan African region alone had 255,000 deaths (Murray et al., 2022, The Lancet, https://doi.org/10.1016/S0140-6736(21)02724-0).

Assoc. Prof. Charles Masembe, Department of Zoology, Entomology and Fisheries Sciences, CoNAS, Makerere University. He conducts research on animal diseases using molecular epidemiology tools with special focus on African Swine Fever genetics.
Assoc. Prof. Charles Masembe, Department of Zoology, Entomology and Fisheries Sciences, CoNAS, Makerere University. He conducts research on animal diseases using molecular epidemiology tools with special focus on African Swine Fever genetics.

The Strategic Research Agenda by the Joint Programming Initiatives (JPI) calls for transnational studies on AMR in both terrestrial and aquatic environments. Indeed, the role of livestock, wildlife and migratory birds in the spread of AMR has previously been under-emphasized, yet they are major reservoirs of ARB and ARG.

Dr Peter Akoll engages stakeholders on the commonly used antibiotics and the potential sites for sample collection
Dr Peter Akoll engages stakeholders on the commonly used antibiotics and the potential sites for sample collection

The PAIRWISE Project is being implemented in three countries in Europe, and two in Africa. PAIRWISE is investigating the risks posed to human health and the environment by pollutants and pathogens present in water resources. The project also aims to investigate the dispersal of ATB, ARB and ARG downstream Wastewater Treatment Plants (WWTPs) by comparing different geographical/climatic regions, wastewater management practices and types of water bodies.

Project partners include; National Veterinary Institute (SVA), Sweden; Norwegian Institute for Water Research (NIVA), Norway; Linköping University (LiU), Sweden; Doñana Biological Station, Higher Council for Scientific Research, Spain; National Research Institute for Rural Engineering, Water, and Forestry, Tunisia; Faculty of Medicine Ibn Al-Jazzar Sousse, Tunisia; and the College of Natural Sciences,  Makerere University, Uganda.

Mr. David Nuwagaba, Mbarara District Natural Resources Officer sharing his views at the stakeholders meeting 
Mr. David Nuwagaba, Mbarara District Natural Resources Officer sharing his views at the stakeholders meeting 

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 869178-AquaticPollutants, Joint Programming Initiative on Anti-microbial Resistance (JPIAMR), www.waterjpi.eu; and JPI Oceans, www.jpi-oceans.eu. For Uganda, the three-year project is funded by the Swedish International Development Agency (Sida). The African Population and Health Research Center, Nairobi, www.aphrc.org coordinates the funding in Uganda.

One of the study areas, River Rwizi Catchment
One of the study areas, River Rwizi Catchment

In Uganda, the research activities are being conducted by researchers from the College of Natural Sciences, Makerere University including: Prof. Charles Masembe (Principal Investigator), Dr. Robinson Odong, Dr. Peter Akoll, Mr. Mayega Johnson (Department of Zoology, Entomology and Fisheries Sciences) and Mr. John Omara (Department of Biochemistry and Sports Sciences) as team members. The study area in Uganda includes the catchment of River Rwizi, Lake Mburo National Park, and River Aswa.  

The Team visits one of the study areas, River Rwizi Catchment
The Team visits one of the study areas, River Rwizi Catchment

The research will contribute towards better understanding of the factors which influence the occurrence and spread of AMR in water systems, livestock farms, and birds. It will also contribute towards the Government of Uganda’s framework to combat the threat of AMR, through the National AMR Action Plan; design policies to reduce the risks of AMR, and the costs incurred for animal and human disease management.

Dr Peter Akoll moderated the discussion on potential sites for sample collection
Dr Peter Akoll moderated the discussion on potential sites for sample collection

Makerere University PAIRWISE Consultative Meeting in Mbarara

On 31st May 2022, the project team from the Department of Zoology, Entomology and Fisheries Sciences led by Prof. Charles Masembe (Principal Investigator) held a consultative meeting to get buy-in and introduce the PAIRWISE Project to the key stakeholders in Greater Mbarara and River Rwizi catchment. The meeting also aimed to receive input from key stakeholders regarding the use of antibiotics in Greater Mbarara district and River Rwizi catchment, to document challenges of Antimicrobial Resistance and identify potential sites for fieldwork.  

Mr John Omara from the Department of Biochemistry and Sports Sciences sharing his views on the study
Mr John Omara from the Department of Biochemistry and Sports Sciences sharing his views on the study

The meeting was attended by administrators, senior health, water and environmental officers in Mbarara City and District including:

  1. The District Chief Administration Officer represented by Mr Bakashaba Innocent
  2. Mr David Nuwagaba, the District Natural Resources Officer
  3. Mr Tumwebaze Herbert, Environment Officer, Mbarara City
  4. Dr Oriokot Francis, Deputy Director, Mbarara Regional Referral Hospital
  5. Dr Akashaba Andrew, Mbarara District Veterinary Officer
  6. Mr Mwesigye Joseph, Environment Officer, Mbarara District
  7. Mr Katongole Joseph, a farmer in Mbarara District

Mr Ayebare Calist, Fisheries Officer, Isingiro District, and a fresh graduate (May 2022, Makerere University 72nd Graduation) assisted in organizing the Stakeholders meeting. During the meeting, Dr Robinson Odong on behalf of Prof. Charles Masembe shared the project overview with participants, outlining the challenges of AMR, and expectations from the research. Stakeholders brainstormed and listed the commonly used antibiotics and the potential sites for sample collection. The research will take the One Health Approach, encompassing aspects of human, animal and environmental health.

Some of the District officials who participated in the PAIRWISE project consultative meeting in Mbarara City
Some of the District officials who participated in the PAIRWISE project consultative meeting in Mbarara City

Capacity Building under PAIRWISE Project

As part of the PAIRWISE capacity building component, the project is supporting research activities of two graduate students: Ms. Ndinawe Ruth Pamela (Master of Science in Molecular Biology) studying “The dispersal of antimicrobial resistance bacteria and genes through aquatic birds under different climatic and geographical conditions”; and Mr. George Katende (Master of Science in Immunology and Clinical Microbiology), studying “Characterization of clinically important antibiotic resistant bacteria and genes in river waters upstream and downstream of WWTPs and hospital effluent” https://cns.mak.ac.ug/blog/call-applications-msc-scholarship-under-pairwise-project.

More at: https://mobile.twitter.com/makconas

Mr Ayebare Calist (R), Fisheries Officer, Isingiro District and Mr Katongole Joseph, a farmer in Mbarara District at the stakeholders meeting
Mr Ayebare Calist (R), Fisheries Officer, Isingiro District and Mr Katongole Joseph, a farmer in Mbarara District at the stakeholders meeting
The Team on the banks of River Rwizi, Isingiro District.
The Team on the banks of River Rwizi, Isingiro District.
Cattle watering in River Rwizi, Isingiro District. The water is also used for human consumption. PAIRWISE is investigating the risks posed to human health and the environment by pollutants and pathogens present in water resources
Cattle watering in River Rwizi, Isingiro District. The water is also used for human consumption. PAIRWISE is investigating the risks posed to human health and the environment by pollutants and pathogens present in water resources
A student drawing water from River Rwizi
A student drawing water from River Rwizi
The Project team with farmers in Isingiro District
The Project team with farmers in Isingiro District

View on CoNAS

Natural Sciences

Mak Paves Path to Biodiversity Leadership: Inaugural ABS Project Workshop Strengthening Uganda’s Nagoya Protocol Capacity

Published

on

The Principal CoNAS-Prof. Tumps Ireeta (7th L), Director, Quality Assurance Directorate (QAD)-Dr. Cyprian Misinde (6th L), Dean, School of Biosciences-Prof. Arthur Kajungu Tugume (6th R), Project PI at Makerere University-Dr. Katuura Esther (4th R) and other officials at the Inception Workshop for the ABS Project on 7th November 2023 in the Telepresence Centre. Senate Building, Makerere University, Kampala Uganda, East Africa.

By Laban Lwasa

In a groundbreaking event that unfolded at Makerere University‘s Telepresence Center on November 7, 2023, the Inception Workshop for the ABS Project took center stage, hosted by the College of Natural Sciences (CoNAS), Department of Plant Sciences, Microbiology, and Biotechnology. Prof. Tumps Ireeta, Principal of CoNAS, set the tone with a warm welcome, highlighting Uganda’s rich biodiversity and the pivotal role of the Nagoya Protocol in ensuring the legal utilization of genetic resources. The collaboration between NEMA and Makerere University, supported by the GEF, aims to equip professionals with ABS knowledge and position Makerere at the forefront of Nagoya Protocol compliance.

Prof. Arthur Kajungu Tugume, Dean of the School of Biosciences, CoNAS. ABS Project Inception Workshop, Telepresence Centre, Senate Building, Makerere University, Kampala Uganda, East Africa.
Prof. Arthur Kajungu Tugume, Dean of the School of Biosciences, CoNAS.

Prof. Arthur Kajungu Tugume, Dean of the School of Biosciences, emphasized the project’s significance in institutional capacity strengthening for the Nagoya Protocol’s implementation in Uganda, showcasing the School of Biosciences as a hub for genetic resource research and training. The pilot project, in collaboration with NEMA, GEF, and UNEP, aims to expand countrywide and potentially across the African continent. It seeks to empower a skilled workforce informed on ABS issues, contributing to economic development and poverty eradication as aligned with SDG 1.

Mr. Achuu Peter, Project Manager from NEMA. ABS Project Inception Workshop, Telepresence Centre, Senate Building, Makerere University, Kampala Uganda, East Africa.
Mr. Achuu Peter, Project Manager from NEMA.

Mr. Achuu Peter, Project Manager from NEMA, highlighted Uganda’s extraordinary biodiversity and the need to explore the benefits of genetic resources for medicines, food, and more. He emphasized the importance of the Nagoya Protocol in mitigating biodiversity loss and highlighted challenges faced by Uganda in terms of weak institutional capacity, inadequate policies, and lack of coordination for ABS. The project focuses on strengthening ABS frameworks, capacity building, community-level management, and raising awareness to ensure equitable benefits from genetic resource utilization.

Mr. Daniel Abowe, UNCST ABS Project Officer. ABS Project Inception Workshop, Telepresence Centre, Senate Building, Makerere University, Kampala Uganda, East Africa.
Mr. Daniel Abowe, UNCST ABS Project Officer.

Mr. Daniel Abowe, UNCST ABS Project Officer, shed light on the complex landscape of national ABS laws in Uganda, resulting in legal complexity and high transaction costs for users. He also detailed the Uganda research approval process, emphasizing UNCST’s role in ABS implementation, which includes issuing access permits and ensuring benefit-sharing agreements. The multifaceted project aims to align Uganda with the Nagoya Protocol’s goals and foster collaboration between higher institutions and local communities for the management of genetic resources.

Dr. Katuura Esther, the Project Principal Investigator at Makerere University. ABS Project Inception Workshop, Telepresence Centre, Senate Building, Makerere University, Kampala Uganda, East Africa.
Dr. Katuura Esther, the Project Principal Investigator at Makerere University.

Dr. Katuura Esther, the Project Principal Investigator at Makerere University, highlighted the institution’s pivotal role in training and research. Makerere University aspires to be a thought leader, committed to providing transformative teaching, learning, research, and services that cater to dynamic national and global needs. The institution’s strategic goals encompass leadership in high-quality programs, knowledge dissemination, research, scholarship promotion, and corporate social responsibility. Dr. Esther also addressed the challenges and opportunities in preserving indigenous knowledge, emphasizing the role of digital technologies and collaboration between research institutions and local communities.

The programs designated for updating at Makerere University are a comprehensive effort to align with the Nagoya Protocol. Notable among these programs are BSc Applied and Economic Botany, BSc in Conservation Biology, Bachelor of Biotechnology, Masters in Botany, Masters in Genetics, Masters in Plant Pathology and Crop Science, and Masters in Economic Botany. This holistic approach aims to contribute to the conservation and equitable utilization of genetic resources.

Dr. Cyprian Misinde, the Director of Quality Assurance at Makerere University. ABS Project Inception Workshop, Telepresence Centre, Senate Building, Makerere University, Kampala Uganda, East Africa.
Dr. Cyprian Misinde, the Director of Quality Assurance at Makerere University.

Dr. Cyprian Misinde, the Director of Quality Assurance at Makerere University, emphasized the importance of incorporating international and global standards into the academic curriculum. He underscored the crucial role of projects like ABS in enhancing the capacity of professionals and equipping them to become part of a globally competitive workforce. This workshop marked a significant stride in Uganda’s journey towards sustainable biodiversity management and conservation, creating a ripple effect that extends far beyond its borders, leaving a lasting impact on the world stage.

Laban Lwasa is the Senior Administrative Assistant, Makerere University, Grants Administration and Management Support Unit (GAMSU)

Continue Reading

Natural Sciences

Ugandan student Dorothy Akoth wins 2023 GBIF Graduate Researchers Award

Published

on

Dorothy Akoth, Master's student at Makarere University and 2023 GBIF Graduate Researchers Award winner. Photo by Christine Elong / National Fisheries Resources Research Institute.

Ms. Dorothy Akoth, a Master’s student at the College of Natural Sciences (CoNAS), Makerere University has been named one of two winners of the 2023 GBIF Graduate Researchers Award. An expert jury selected Akoth, who was nominated by the Uganda National Council for Science and Technology together with National Fisheries Resources Research Institute (NaFIRRI), for the instrumental role of her research in improving the knowledge of the distribution and imperilment status of 110 native fish species outside the iconic Haplochromine tribe of East African cichlids. The student was supervised by Prof. Fredrick Muyodi and Dr. Jackson Efitre
from the Department of Zoology, Entomology and Fisheries Sciences at CoNAS, Makerere University, and Dr Vanny Natugonza of Busitema University.

Since its inception in 2010, the annual GBIF Graduate Researchers Award (previously the Young Researchers Award) has sought to promote and encourage innovation in biodiversity-related research using data shared through the GBIF network.

Details at:
https://www.gbif.org/news/6qTuv5Xf1qa05arROvx7Y1/ugandan-student-dorothy-akoth-wins-2023-gbif-graduate-researchers-award

Continue Reading

Natural Sciences

CARTA Fellow Anywar Selected as Fellow of ASLP

Published

on

Dr. Godwin Anywar, Department of Plant Sciences, Microbiology and Biotechnology, College of Natural Sciences (CoNAS), Makerere University. Photo: CARTA. Kampala Uganda, East Africa.

Godwin Anywar (cohort 6 graduate, Makerere University) was selected as a fellow of the Africa Science Leadership Programme (ASLP) based at the Future Africa Campus at the University of Pretoria, South Africa, on September 8, 2023. 

Within the month, he:

  • Will be participating in the Uganda-Swiss Museum Cooperation Workshop from September 24 – October 4, 2023, in Kampala, Uganda, and will present on ‘Traditional Medicine in Transition.’
  • Presented a keynote paper on ‘Mental Health and Wellbeing during the PhD Journey’ at the Makerere University Business School (MUBS) 27th Annual International Management Conference (AIMC) under the theme “Leveraging Governance, Human Capital and Technology for Sustainability in Kampala – Uganda on September 25 – 27, 2023.
  • Presented a paper on ‘The Cannabis/Marijuana (Cannabis sativa L.) Landscape in Africa: An Overview of its Cultivation and Legal Aspects’ at the 20th International Napreca Conference on Natural Network for East and Central Africa (NAPRECA) in Harare, Zimbabwe on September 20, 2023.
  • Attended the German Academic Exchange Service (DAAD) Science Forum at the University of Nairobi on September 20, 2023, to celebrate 50 years of DAAD in East Africa.

Source: CARTA Newsletter Issue 69

Continue Reading

Trending