The Vice Chancellor, Prof. Barnabas Nawangwe (2nd R) with the OPTIBOV Project team after their meeting at CTF1 on 25th April 2022. Right is the Makerere University coordinator, Dr Donald Kugonza.
OPTIBOV: Genetic Characterization of Cattle Populations for Optimal Performance in Africa Eco Systems
A large variety of local indigenous and commercial cattle breeds has been produced as a result of domestication and selection. This variety ensures the capability and adaptability of livestock to fulfil its role in food production under different circumstances, now and in the future. Local breeds exhibit unique adaptive features to harsh environments, which can be useful for adjusting mainstream breeds to climate change. Simply transferring high producing commercial animals to the African continent, will not be the solution due to low performance and even low survival under these harsh environments (ecosystems). The aim of the OPTIBOV project is to improve production and survival of traditional/indigenous breeds adapted to the local environments in Africa. This will secure the future of these well adapted traditional/indigenous local breeds.With combined effort from partners across the globe, the OPTIBOV project will help maintain traditional cattle breeds, capture adaptation, use known variations in production, train, educate & involve stakeholders to perform optimal breeding.
The OPTIBOV project team during the seminar at CAES.
The project is coordinated in The Netherlands (Wageningen University and Research Centre). Participating institutions include; Makerere University, Uganda; Natural Resources Institute Finland; Agricultural Research Council Pretoria, South-Africa; University of Porto, Portugal; Cairo University, Egypt; and Taurus Foundation Netherlands.
Project members include; Dr. Richard Crooijmans, Wageningen University, The Netherlands; Dr. Donald Kugonza, Department of Agricultural Production, Makerere University; Prof. Juha Kantanen, Natural Resources Institute Finland; Dr. Nasser Ghanem, University of Cairo, Egypt; Dr. Linky Makgahlela, Pretoria, South Africa; and Dr. Catarina Ginja from Portugal.
The project is supported by LEAP-Agri, a joint Europe Africa Research and Innovation (R&I) initiative related to Food and Nutrition Security and Sustainable Agriculture (FNSSA).
An important deliverable of the project is a new genotyping assay specific for African cattle breeds which will include markers associated with specific traits.
Dr. Richard Crooijmans, OPTIBOV Project leader from Wageningen University, The Netherlands.
Expected outcomes and impact:
A uniform bovine phenotype scoring list for adaptation traits.
Genome-wide information of the traditional breeds. Giving knowledge on the amount of diversity but also on the amount of inbreeding, detection of potential genetic defects and selective sweeps related to adaptation to a specific environment.
The obtained information can be used to improve traits by selection of animals within or over breeds such as longevity, production and resistance to diseases. This will increase production, longevity and reduces cost for medical treatments which will result in breed performance in the next generations.
Training of young researchers will be conducted to use the latest technology and techniques and how to implement the findings in breeding.
Involvement of all stakeholders up to farmers by creating an APP, database and website to submit data and actively participate within the research.
Hybrid seminar
On 25th April 2022, the project team met at the College of Agricultural and Environmental Sciences (CAES), Makerere University to share updates on activities in the respective countries. The hybrid seminar was hosted by Dr Donald Kugonza and Dr Morris Agaba.
The OPTIBOV Project team led by Dr. Donald Kugonza (extreme Left) meeting the Vice Chancellor, Prof. Barnabas Nawangwe (C).
Seminar presentations/issues being researched
Traditional cattle genomics: search for adaptive markers–Dr Richard crooijmans, Wageningen University in The Netherlands;
Developments in SNP genotyping and next generation sequencing in South African indigenous cattle – Dr AA Zwane, a Researcher in Animal Breeding and Genetics, Agricultural Research Council-Animal Production (ARC-AP), Irene, Pretoria, South Africa;
Molecular responses of heat stress during early embryonic development and alleviation strategies– Dr Nasser Ghanem from the Department of Animal Production, Faculty of Agriculture, Cairo University, Egypt;
Application of genomics for livestock genetic improvement–Dr Linky Makgahlela, ARC-Animal Production, South Africa;
Genomic characterization of northern native cattle breeds-Prof.JuhaKantanen, Natural Resources Institute Finland;
Phenotypic and Genotypic Characterisation of Ankole, Ntuku and Nganda cattle of Uganda-Dr.Behabura Generous Betunga, an MSc. Animal Science student in the Department of Agricultural Production, CAES;
Investigating the production and adaptive traits of indigenous cattle to eastern Uganda ecosystems-Waibi Sarah, an MSc. Livestock Development student at the College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University;
The use of Genomic Tools to Improve Cattle, an Archaeogenomics Perspective– Dr Catarina Ginja
Dr. Catarina Ginja shares her views during the meeting.
Issues arising from the research
1. Developments in SNP genotyping and next generation sequencing in South African indigenous cattle – Dr. A. A. Zwane
There is notable difference in using single nucleotide polymorphism (SNP) data and whole genome sequence (WGS) data in characterizing SA indigenous cattle breeds
WGS data holds the potential for the improvement of indigenous livestock breeds due to the in-depth analysis genome-wide
Genetic diversity studies give the understanding of population structure, demographic history, introgression and heterozygosity levels in South Africa indigenous cattle
Identification of selective signatures provides insight into selection events that have shaped the genomes of indigenous cattle breeds, and allows the identification of important genes
This will allow genomic selection, sooner, in the indigenous breeds, and more studies are needed for other indigenous livestock species
2. Application of genomics for livestock genetic improvement – Linky Makgahlela, ARC-Animal Production, South Africa
Genomics drives biological efficiency of production, boosts livestock contribution for sustainable protein source
Genomics promises cutting-edge solutions: Nutritional needs of all human beings, while safeguarding natural resources, and preventing environmental degradation
Genomics enables farmers to increase efficiency, decrease production costs & prophylactics and limits expenditure of resources
Research (and capacity development) ongoing for better understanding of breeds and to put science to practice
Dr. Behabura Generous Betunga presents her research progress report.
3. Genomic characterization of northern native cattle breeds – Prof. Juha Kantanen, Natural Resources Institute Finland
The gene expression analysis of the northern Eurasian breeds revealed;
Several differentially expressed genes (DEG) that were associated with the eicosanoid metabolic process (ALOX15, ALOX5 and HPGD) in northern Finncattle and with immunity (CCL4, CCL5 CX3CR1, CXCR6 and PRF1) and the regulation of lipid transport (ABCA1, ABCG1, IRS2 and THBS1) in Yakutian cattle.
The genes involved in the immune system are also associated with environmental adaptation.
The eicosanoid metabolic process was previously found to be involved in the hibernation of brown bears (Ursusarctos) and indigenous peoples associated with seasonal changes. These findings indicate a convergent evolution that may have occurred in different mammalian species living in northern and sub‐arctic environments.
4. Phenotypic and Genotypic Characterisation of Ankole, Ntuku and Nganda cattle of Uganda – Dr. Behabura Generous Betunga, Makerere University
The Ugandan cattle herd is comprised of 93.3 percent of indigenous breeds and their crossbreeds which are mainly; Long-horned cattle of Uganda (Sanga) (Bostaurusindicus); Zenga breeds (Sanga and Zebu crosses); East African short-horn Zebu (Bosindicus). The OPTIBOV breeds of interest in Uganda are; Long horned Ankole cattle (South-Western Uganda); Nganda cattle (Central-Uganda) and Ntuku cattle (Mid-Western Uganda). The study aims to carry out phenotypic characterization for performance traits and draw a genomic growth curve for Ankole, Ntuku and Nganda cattle under different management systems for a period of 0 to 18 months in Uganda. It also aims to carry out genetic characterization and measure the genetic relationship between the Ankole, Ntuku and Nganda cattle in Uganda; and to assess selection techniques (natural and human mediated) of Ankole, Ntuku and Nganda cattle of Uganda. Meetings have been held with farmers and animals selected for sampling and samples collected for analysis.
Ankole cattleNtuku Cattle
Issues arising include;
The Indigenous cattle breeds are at the threat of genetic erosion. There is need for Phenotypic & genotypic Characterization for the performance traits of the Ankole, Ntuku and Nganda
5. Investigating the production and adaptive traits of indigenous cattle to eastern Uganda ecosystems
Cattle is a valuable source of income, employment & a major source of nutrition to people in the East especially Karamoja and Bukedi in Tororo. Angoria Ting and Cheptoyoi are the indigenous cattle breeds in Karamoja: Karamajong women prefer rearing goats to cows. The study aims to;
To phenotypically characterize the performance and adaptive traits of the Nkedi and Karimajong cattle
To develop indices for assessing the productivity of the Nkedi and Karimajong cattle
To assess status and risk of erosion of the two indigenous cattle genetic resources
In the course of the seminar, the OPTIBOV project team paid a courtesy call on Makerere University Vice Chancellor, Prof. Barnabas Nawangwe who congratulated them upon winning the research grant.“As we celebrate 100 years of teaching, research and innovation, such projects are vital in pushing forward our agenda of transforming Makerere into a research-led University,” he noted, pledging to accord the researchers all the support they need to achieve the project objectives.
The project leader at Makerere University, Dr. Donald Kugonza expressed gratitude to the Vice Chancellor for the support he accorded the team in their bid for the project.
The Department of Food Technology and Nutrition (DFTN), Makerere University, in collaboration with Smart Foods Uganda Ltd, successfully conducted a five-day intensive training on soybean value addition and product development from 24th to 28th November 2025. The training was implemented with support from IITA Uganda under the Training for African Agricultural Transformation (TAAT) Soy Compact Project, aimed at strengthening agro-processing capacities and promoting soybean utilization for improved nutrition and livelihoods.
Some of the Processors during the training in the Food Technology and Business Incubation Centre at Makerere University.
The training program was highly practical and skills-oriented, featuring extensive hands-on sessions designed to equip participants with applicable processing and product development competencies. Most of the practical activities were hosted at Makerere University’s Food Technology and Business Incubation Centre (FTBIC). Participants also benefited from an industry exposure and experiential learning session at Smart Foods Uganda Ltd in Bweyogerere, where they gained first-hand insights into commercial-scale soybean processing operations, quality control systems, and product marketing strategies.
Some of the products developed.
Key thematic areas and technologies covered during the training included soybean nutrition and associated health benefits; assessment of quality attributes of soybeans and soy-based products; application of Good Hygiene Practices (GHP) and Good Manufacturing Practices (GMP); and processing of high-quality soy products. Practical sessions focused on the production of soymilk, tofu, soy yoghurt, soy flour, and soy coffee, as well as the formulation of soy-fortified composite porridge flours. Participants were also trained in the development of various soy-based bakery products, including bread, mandazi, daddies, and baghia. In addition, sessions on marketing, branding and positioning of soy products, as well as UNBS certification requirements and documentation, were conducted to enhance market readiness and regulatory compliance.
The yoghurt produced during the training session.
The training attracted a total of 57 participants, comprising small-scale soybean processors and graduating university students, thereby fostering knowledge exchange between academia and industry. Overall, the training contributed significantly to building technical capacity in soybean value addition, promoting entrepreneurship, and supporting the development of nutritious, market-oriented soy-based products in Uganda. The School of Food Technology, Nutrition, and Bioengineering, under the leadership of Dr. Julia Kigozi (Dean), conducts periodical trainings for agro-processors across the country to enhance technical capacity, improve product quality, and promote the adoption of modern, safe, and sustainable food processing practices. These trainings are designed to equip agro-processors with practical skills in food safety, quality assurance, value addition, post-harvest handling, nutrition, and bioengineering innovations, thereby enabling them to meet national and international standards. Through this outreach, the School contributes to strengthening agro-industrial development, reducing post-harvest losses, supporting entrepreneurship, and improving food and nutrition security while fostering stronger linkages between academia, industry, and communities.
The Department of Tourism at the College of Agricultural and Environmental Sciences (CAES) on Thursday, 11 December 2025, hosted Prof. Sofia Asonitou from the University of West Attica, Greece. Prof. Asonitou serves as the Regional Coordinator for the Sub-Saharan Africa region under the Erasmus+ International Credit Mobility (ICM) framework at her institution.
During her engagement with the Department team led by Prof. Jim Ayorekire, deliberations centred on strengthening avenues for international academic cooperation.
The team during their meeting at the Department of Tourism at CAES.
The meeting highlighted several key areas of collaboration, including the initiation of student and staff exchanges under the Erasmus+ mobility program and capacity building in tourism governance. The team also explored the development of a joint masters degree program and the design of micro-credit courses aimed at addressing emerging skills gaps within the tourism sector.
Prof. Jim Ayorekire receives a souvenir from Prof. Sofia Asonitou.
Prof. Asonitou’s visit marked an important step toward deepening institutional partnerships and enhancing the global outlook of tourism education and research within CAES.
The team at the School of Forestry, Environmental, and Geographical Sciences at CAES.
The Department of Tourism, which was carved out of the former Department of Forestry, Biodiversity, and Tourism, now operates as an independent academic unit offering a diverse and comprehensive range of programmes. The programmes are designed to equip students with the knowledge, skills, and practical experience necessary to thrive in various sectors of the tourism industry, including sustainable tourism development, hospitality management, and eco-tourism.
The African Union’s Agenda 2063 articulates a clear continental ambition; to unlock Africa’s potential to feed itself and to harness the transformative power of its greatest asset, its people. While natural resources remain abundant and diverse, Africa’s long-term prosperity hinges on the strategic cultivation of human capital through robust, forward-looking education systems.
Like many governments across the continent, the Government of Botswana, the host of the Regional Universities Forum for Capacity Building in Agriculture (RUFORUM)’s 21st Annual General Meeting (AGM), aligns closely with the Sustainable Development Goals of zero hunger and no poverty. It also upholds the collective aspirations of African Heads of State and Government expressed in the Kampala Declaration under the Comprehensive African Agricultural Development Programme (CAADP).
Against this backdrop, the pre-AGM session on transformative education and ecosystem engagement convened hundreds of scholars, policymakers, and thought leaders from Africa and beyond. The discussions underscored a shared urgency that strategic collaboration must move from concept to action if the continent is to confront its pressing challenges of food insecurity, public health vulnerabilities, conflict and displacement, youth unemployment, and the persistent pressures of migration. The message was clear; Africa’s transformation requires not isolated interventions, but integrated, interdisciplinary solutions.
In fulfilling the CAADP agenda, universities stand at the forefront. They must leverage every available opportunity to generate workable, evidence-based solutions through science, technology, and innovation. However, they cannot act alone. National Agricultural Research Systems, the private sector, civil society, and development partners must each play an indispensable role in strengthening Africa’s education and agricultural systems. Together, these institutions form the ecosystem that will determine whether Africa can translate its ambitions into tangible progress.
The Youth Dividend
Since its establishment at Makerere University in Uganda in 2004, RUFORUM has supported the training of more than 3000 students across the continent at PhD, Masters, undergraduate and Technical and Vocational Education and Training (TVET) level. These scholars, drawn from diverse African countries and hosted in universities across the region, represent a deliberate investment in building Africa’s scientific capacity and advancing pan-African collaboration. Notably, 98% of RUFORUM-supported graduates continue to work within their home countries or regions, reinforcing national and regional development efforts.
Flags of participating nations are carried through the conference room.
A key contributor to this impact is the Mastercard Foundation supported initiative, Transforming African Agricultural Universities to Meaningfully Contribute to Africa’s Growth and Development (TAGDev2.0). This programme strengthens universities, Technical, and Vocational Education and Training (TVET) institutions to drive inclusive, equitable, and climate-resilient transformation of agriculture and agri-food systems. Through experiential learning, practical skills development, and youth empowerment, TAGDev enhances the ability of young Africans to engage meaningfully in agriculture as innovators, leaders, and entrepreneurs.
Across both TAGDev 1.0 and 2.0, thousands of young women and men have been equipped to establish profitable enterprises and create employment opportunities within their communities.
This transformative impact was evident during a keynote address by Dr. Yeukai Mlambo from the MasterCard Foundation followed by a panel session where four young entrepreneurs and beneficiaries of RUFORUM MasterCard supported programmes, shared their journeys. Their enterprises span a wide spectrum. From improving and multiplying high-quality potato seed in Nakuru Kenya by Winnie Wambugu, to equipping differently abled persons (PWDs) with agronomy and entrepreneurship skills in Uganda by Zena Saliru, to skilling refugees in the west Nile region of Uganda by Gordon Victor Akejo to supporting out-of-school youth to become self-reliant by Kato Omia. These stories illustrate not only the ingenuity of Africa’s youth but also the importance of sustained investment in higher education and innovation ecosystems. They embody the youth dividend that Africa stands to gain if it continues to nurture the potential of its young people.
A moment Africa cannot afford to miss
As the conversations by the young entrepreneurs have made clear, Africa stands at a pivotal moment. The continent’s aspirations captured in Agenda 2063, the SDGs, and the CAADP commitments cannot be realised through intention alone. They demand systems that elevate human capital, institutions that collaborate rather than compete, and education models that prepare young people not merely to seek opportunity but to create it.
The stories shared by emerging entrepreneurs and young scientists are more than inspiring anecdotes; they are proof points. They show that when universities are empowered, when partnerships are genuine, and when young people are trusted with the tools and mentorship they need, transformation is already underway.
The scale of Africa’s challenges requires an equal scale in commitment by Governments, universities, research organisations, the private sector, and development partners who must deepen investments in higher education, innovation ecosystems, and youth-focused initiatives. Failure to do so risks squandering one of the continent’s most powerful assets, its demographic dividend.
Africa must therefore double down on transformative education and ecosystem-led collaboration. The momentum witnessed in Botswana should not end with the AGM. It should mark the beginning of renewed resolve to equip Africa’s young people with the skills, networks, and support they need to lead the continent’s next chapter.
The future is already taking shape in laboratories, fields, innovation hubs, and classrooms across the continent. It is time to scale what works and ensure that Africa’s brightest minds are empowered to build the strong and prosperous nations they envision. Collectively, we shall all achieve the Africa that we want.