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Publications Arising Directly from THRiVE-2 Funding in 2021

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  1. Milugo TK, Tchouassi DP, Kavishe RA, Dinglasan RR, Torto B. Root exudate chemical cues of an invasive plant modulate oviposition behavior and survivorship of a malaria mosquito vector. Sci Rep. 2021 Jul 20;11(1):14785. https://doi.org/10.1038/s41598-021-94043-5.PMID: 34285252
  2. Kaaya, R.D., Kajeguka, D.C., Matowo, J.J, Ndaro A.J., Mosha FW, Chilongola J. O. and Kavishe R. A. Predictive markers of transmission in areas with different malaria endemicity in north-eastern Tanzania based on seroprevalence of antibodies against Plasmodium falciparum. BMC Res Notes 14, 404 (2021).
    doi: 10.1186/s13104-021-05818-y
  3. Mosha MV, Msuya SE, Kasagama E, Ayieko P, Todd J, Filteau S.PLoS One. Prevalence and correlates of overweight and obesity among primary school children in Kilimanjaro, Tanzania. 2021 Apr 22;16(4):e0249595. doi: 10.1371/journal.pone.0249595. eCollection 2021.PMID: 33886578
  4. Mosha MV, Kasagama E, Ayieko P, Todd J, Msuya SE, Grosskurth H, Filteau S. Description and comparison of physical activity from self-reports and accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study. AAS Open Res. 2021 May 17;3:40. doi: 10.12688/aasopenres.13118.4.eCollection 2020.PMID: 34056542
  5. Mcharo RD, Mayaud P, Msuya SE. Where and how do young people like to get their sexual and reproductive health (SRH) information? Experiences from students in higher learning institutions in Mbeya, Tanzania: a cross-sectional study. BMC Public Health. 2021 Sep 16;21(1):1683. doi: 10.1186/s12889-021-11728-2.PMID: 34530796
  6. Okello E, Ndagire E, Muhamed B, Sarnacki R, Murali M, Pulle J, Atala J, Bowen AC, DiFazio MP, Nakitto MG, Harik NS, Kansiime R, Longenecker CT, Lwabi P, Agaba C, Norton SA, Omara IO, Oyella LM, Parks T, Rwebembera J, Spurney CF, Stein E, Tochen L, Watkins D, Zimmerman M, Carapetis JR, Sable CA, Beaton A. Incidence of acute rheumatic fever in northern and western Uganda: a prospective, population-based study. Lancet Glob Health. 2021 Oct;9(10):e1423-e1430. doi: 10.1016/S2214-109X (21)00288-6. Epub 2021 Aug 19. PMID: 34419237
  7. Beaton A, Okello E, Rwebembera J, Grobler A, Engelman D, Alepere J, Canales L, Carapetis J, DeWyer A, Lwabi P, Mirabel M, Mocumbi AO, Murali M, Nakitto M, Ndagire E, Nunes M, Omara IO, Sarnacki R, Scheel A, Wilson N, Zimmerman M, Zühlke L, Karthikeyan G, Sable CA, Steer AC. Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease. Accepted, NEJM, 8/24/21.
  8. Arthur Kwizera, David P Kateete, Ronald Ssenyonga, Lydia Nakiyingi, Jane Nakibuuka, Christine Namata, Arthur Mwanje, Emmy Okello, Daphne Kabatoro, Noah Kiwanuka, Robert C Bollinger, James Tumwine, Charlotte Summers. Acute Respiratory Distress Syndrome in an African Intensive Care Unit Setting: A Prospective Study of Prevalence and Outcomes. Ann Am Thorac Soc 2021 Oct 19. doi: 10.1513/ AnnalsATS.202103-270RL.
  9. Christine Oryema, Karlmax Rutaro, Sam William Oyet and Geoffrey Maxwell Malinga. Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda Tropical Medicine and Health (2021) 49:92 https://doi.org/10.1186/s41182-021-00384-2
  10. Mulugeta Belay, Begna Tulu, Sidra Younis, David A Jolliffe, Dawit Tayachew, Hana Manwandu, Tenagnework Abozen, Emawayish A Tirfie, Metasebia Tegegn, Aboma Zewude, Sally Forrest, Jonathan Mayito, Jim F Huggett, Gerwyn M Jones, Denise M O’Sullivan, Henny M Martineau, Mahdad Noursadeghi, Aneesh Chandran, Kathryn A Harris, Vlad Nikolayevskyy, Julie Demaret, Stefan Berg, Martin Vordermeier, Taye T Balcha, Abraham Aseffa, Gobena Ameni, Markos Abebe, Stephen T Reece, Adrian R Martineau. Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study. The Lancet Microbe, 2021 Jun. 2(6): p. E267-E275.
  1. Mosha MV, Kasagama E, Ayieko P, Todd J, Msuya SE, Grosskurth H Fulteau S.. Description and comparison of physical activity from self-reports and accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study [version 4; peer review: 2 approved]. AAS Open Res 2021, 3:40 (https://doi.org/10.12688/aasopenres.13118.4)
  2. Philemon RN , Mmbaga BT , Bartlett J, Renju J, Mtuy T, Mboya IB , Msuya SE. Do Women Enrolled in PMTCT Understand the Recommendations: A Case Study from Kilimanjaro 16 June 2021 Volume 2021:15 Pages 1301—1309 DOI https://doi.org/10.2147/PPA.S307847
  3. Okello E, Ndagire E, Muhamed B, Sarnacki R, Murali M, Pulle J, Atala J, Bowen AC, DiFazio MP, Nakitto MG, Harik NS, Kansiime R, Longenecker CT, Lwabi P, Agaba C, Norton SA, Omara IO, Oyella LM, Parks T, Rwebembera J, Spurney CF, Stein E, Tochen L, Watkins D, Zimmerman M, Carapetis JR, Sable CA, Beaton A. Incidence of acute rheumatic fever in northern and western Uganda: a prospective, population-based study. Lancet Glob Health. 2021 Oct;9(10):e1423-e1430. doi: 10.1016/S2214-109X(21)00288-6. Epub 2021 Aug 19. PMID: 34419237
  4. Joel L. Bargul, Kevin O. Kidambasi, Merid N. Getahun, Jandouwe Villinger, Robert S. Copeland, Jackson M. Muema, Mark Carrington, Daniel K. Masiga. Transmission of ‘Candidatus Anaplasma camelii’ to mice and rabbits by camelspecific keds, Hippobosca camelina. PLoS Negl Trop Dis 15(8): e0009671. https://doi.org/10.1371/journal.pntd.0009671
  5. Hudson Onen, Robinson Odong, Moses Chemurot, Frédéric Tripet and Jonathan K. Kayondo Predatory and competitive interaction in Anopheles gambiae sensu lato larval breeding habitats in selected villages of central Uganda. Parasites Vectors (2021) 14:420 https://doi.org/10.1186/s13071-021-04926-9
  6. Dinah Amongin, Frank Kaharuza, Claudia Hanson, Annettee Nakimuli, Susan Mutesi, Lenka Benova and Lynn Atuyambe. “… I would have left that man long time ago but, …” exploring circumstances of and motivators for repeat adolescent birth in Eastern Uganda. Archives of Public Health (2021) 79:142
    https://doi.org/10.1186/s13690-021-00662-9
  7. TK. Milugo, D P. Tchouassi, RA. Kavishe, RR. Dinglasan & B. Torto. Root exudate chemical cues of an invasive plant modulate oviposition behavior and survivorship of a malaria mosquito vector Nature Portfolio Scientific Reports | (2021) 11:14785 | https://doi.org/10.1038/s41598-021-94043-5
  8. Getange, D.; Bargul, J.L.; Kanduma, E.; Collins, M.; Bodha, B.; Denge, D.; Chiuya, T.; Githaka, N.; Younan, M.; Fèvre, E.M.; et al. Ticks and Tick-Borne Pathogens Associated with Dromedary Camels (Camelus dromedarius) in Northern Kenya. Microorganisms 2021, 9, 1414. https://doi.org/10.3390/microorganisms9071414
  1. Dacal E, Bermejo-Peláez D, Lin L, Álamo E, Cuadrado D, Martínez Á, Mousa A, Postigo M, Soto A, Sukosd E, Vladimirov A, Mwandawiro C, Gichuki P, Williams NA, Muñoz J, Kepha S, Luengo-Oroz M. Mobile microscopy and telemedicine platform assisted by deep learning for the quantification of Trichuris trichiura infection. PLoS Negl Trop Dis. 2021 Sep 7;15(9):e0009677. doi: 10.1371/journal.pntd.0009677. PMID: 34492039; PMCID: PMC8448303
  2. JM Muema, JL Bargul, JM Mutunga, MA. Obonyo, GO. Asudi, SN Njeru. Pesticide Biochemistry and Physiology, Neurotoxic Zanthoxylum chalybeum root constituents invoke mosquito larval growth retardation through ecdysteroidogenic CYP450s transcriptional perturbations https://doi.org/10.1016/j.pestbp.2021.104912
  3. Nakanjako D, Kendall D, Sewankambo NK, Razak M H, Oduor B, Odero T, Garcia P, Farquhar C. Building and Sustaining Effective Partnerships for Training the Next Generation of Global Health Leaders. Annals of Global Health. 2021; 87(1): 66, 1–9. DOI: https://doi.org/10.5334/aogh.3214
  4. Mosha MV, Msuya SE, Kasagama E, Ayieko P, Todd J, Filteau S (2021) Prevalence and correlates of overweight and obesity among primary school children in Kilimanjaro, Tanzania. PLoS ONE 16(4): e0249595. https://doi.org/10.1371/journal.pone.0249595
  5. Tushabe P, Howard W, Bwogi J, Birungi M, Eliku JP, Kakooza P, Bukenya H, Namuwulya P, Gaizi J, Tibanagwa M, Kabaliisa T, Mulindwa J, Muhanguzi D, Suchard M, Gumede N, Bakamutumaho B.J. Molecular characterization of non-polio enteroviruses isolated from acute flaccid paralysis patients in Uganda. Med Virol. 2021 Jan 17. doi: 10.1002/jmv.26804. Online ahead of print. PMID: 33458840
  6. Martin Mbonye, Godfrey Siu & Janet Seeley (2021) Conflicted masculinities: understanding dilemmas and (re)configurations of masculinity among men in long-term relationships with female sex workers, in Kampala, Uganda, Culture, Health & Sexuality. DOI: 10.1080/13691058.2021.1891569
  7. Atuhairwe S, Gemzell-Danielsson K, Byamugisha J, Kaharuza F, Tumwesigye NM, Hanson C. Abortion-related nearmiss morbidity and mortality in 43 health facilities with differences in readiness to provide abortion care in Uganda. BMJ Glob Health. 2021 Feb;6(2):e003274. doi: 10.1136/bmjgh-2020-003274.PMID: 33547174
  8. Bagasha P, Namukwaya E, Leng M, Kalyesubula R, Mutebi E, Naitala R, Katabira E and Petrova M. Comparison of the healthrelated quality of life of end stage kidney disease patients on hemodialysis and non-hemodialysis management in Uganda. Bagasha et al. BMC Palliative Care (2021) 20:52 https://doi.org/10.1186/s12904-021-00743-0
  1. Kwizera R, Katende A, Bongomin F, Nakiyingi L and Bruce J. Kirenga. J Misdiagnosis of chronic pulmonary aspergillosis as pulmonary tuberculosis at a tertiary care center in Uganda: a case series. Med Case Reports (2021) 15:140 https://doi.org/10.1186/s13256-021-02721-9
  2. Nattoh G, Bargul JL, Magoma G, Mbaisi, L, Butungi H, Mararo E, E Teal, JK Herren (2021) The fungus Leptosphaerulina persists in Anopheles gambiae and induces melanization. PLoS ONE 16(2): e0246452. https://doi.org/10.1371/journal.pone.0246452
  3. D. Abera, CK Kibet, T Degefa, L Amenga‑Etego, JL Bargul, and L Golassa. Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia Malar J (2021) 20:129 https://doi.org/10.1186/s12936-021-03660-y
  4. Richard Kwizera, Emmanuel Mande, Denis Omali, Samuel Okurut, Sheila Nabweyambo, Rose Nabatanzi, Damalie Nakanjako and David B. Meya. Translational research in Uganda: linking basic science to bedside medicine in a resource limited setting. J Transl Med (2021) 19:76 https://doi.org/10.1186/s12967-021-02747-z
  5. Amongin D, Kågesten A, Tunçalp Ö, Nakafeero M, Atuyambe L, Hanson C, Benova L. Later life outcomes of women by adolescent birth history: analysis of the 2016 Uganda Demographic and Health Survey. BMJ Open 2021;11:e041545. doi:10.1136/ bmjopen-2020-041545
  6. Atuhairwe S, Gemzell-Danielsson K, Byamugisha J, et al. Abortion- related near-miss morbidity and mortality in 43 health facilities with differences in readiness to provide abortion care in Uganda. BMJ Global Health 2021;6:e003274. doi:10.1136/ bmjgh-2020-003274
  7. Milugo TK, Tchouassi DP, Kavishe RA, Dinglasan RR, Torto B. Derivatization increases mosquito larvicidal activity of the sesquiterpene lactone parthenin isolated from the invasive weed Parthenium hysterophorus. Pest Manag Sci. 2021 Feb;77(2):659-665. doi: 10.1002/ps.6131. Epub 2020 Oct 26.PMID: 33034953

Read more in the THRiVE Newsletter Oct-Dec 2021

Mark Wamai

Research

Mak-RIF Bi-Annual Bulletin Issue 6: Jan-Jun 2026

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Prof. Barnabas Nawangwe (L) presents Prof. Daniel Branch (C) with the Makerere necktie and Makerere@100 Coffee Table Book as Prof. Fred Masagazi Masaazi (R) witnesses during his visit on 13th February 2026. Makerere University, Kampala Uganda, East Africa.

It is my pleasure to present the sixth issue of the Makerere University Research and Innovations Fund (Mak-RIF) Bi-Annual Bulletin, highlighting the remarkable progress made between January and June 2026 in advancing research, innovation, knowledge translation, and capacity building at Makerere University.

This edition demonstrates the transformative impact of research supported by the Government of Uganda through Mak-RIF. Across diverse disciplines, researchers continue to generate practical, evidence-based solutions to Uganda’s most pressing development challenges, including food security, public health, clean energy, climate resilience, education reform, digital transformation, and public sector productivity. These achievements reaffirm the critical role of research and innovation in driving national development and improving the lives of Ugandans.

The stories featured in this bulletin are a testimony that Makerere University is strengthening its position as a research-intensive institution committed to producing knowledge that addresses societal needs. Through technologies that convert invasive water hyacinth into renewable fuel, innovations in food safety through machine learning, improved agricultural technologies, digital public sector solutions, groundbreaking advances in teacher education, and more, researchers continue to demonstrate that locally generated knowledge can deliver globally relevant solutions.

Equally encouraging is the University’s continued commitment to building strategic international partnerships. Makerere’s engagement with the University of Warwick reflects our shared vision of strengthening collaborative research, graduate training, innovation, and institutional capacity. Such partnerships expand opportunities for our researchers and students while contributing to the global exchange of knowledge required to address increasingly complex development challenges.This issue also highlights Mak-RIF’s growing emphasis on research knowledge translation. Through dedicated capacity-building initiatives, researchers are being equipped to communicate their findings more effectively to policymakers, practitioners, industry, and the public. By strengthening the interface between research, policy, and practice, we are ensuring that scientific evidence informs decision-making and delivers measurable impact beyond academia.

The continued growth in high-quality research publications showcased in this bulletin further demonstrates the increasing visibility and influence of Makerere University’s research community. These scholarly contributions not only advance scientific knowledge but also strengthen Uganda’s participation in global research while fostering innovation, collaboration, and evidence-informed policymaking.

These accomplishments would not have been possible without the unwavering support of the Government of Uganda, whose investment in Mak-RIF continues to strengthen the University’ research and innovation ecosystem. I commend our researchers, project teams, University leadership, industry collaborators, government MDAs, and communities for their commitment and collaboration. I invite you to explore the inspiring stories presented in this bulletin and celebrate the collective achievements of our researchers and Makerere University.

Prof. Fred Masagazi-Masaazi
Chairperson, Grants Management Committee (GMC)

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UNCST Accredits Over 90 Makerere Staff in Good Research Review Practice

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Prof. Tonny Oyana and Prof. Robert Wamala with participants at the close of the GRRP Training on 24th July 2026. Closing Ceremony of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 24th July 2026, MakSPH Auditorium, Kampala Uganda, East Africa.

The Uganda National Council for Science and Technology (UNCST) on 24th July 2026 accredited over 90 Senior Academic Members of staff that form Makerere University‘s Research Ethics Committees (RECs) in Good Research Review Practice (GRRP) after an intensive three-day Training. The closing ceremony was presided over by the Deputy Vice Chancellor (Academic Affairs)-DVCAA Prof. Sarah Ssali who was represented by the Principal, College of Computing and Information Sciences (CoCIS), Prof. Tonny Oyana.

UNCST’s Role Appreciated

In his remarks, Prof. Oyana reiterated the core function that research plays in Makerere University‘s mission and noted that excellence in research must always be underpinned by excellence in research ethics. “Research Ethics Committees play a vital role in fulfilling this responsibility,” he stated.

“Your decisions influence not only the quality and credibility of research conducted at the University but also the trust that research participants, communities, funding agencies, policymakers, and the public place in our institution,” remarked the DVCAA, who underscored the pivotal role of RECs in upholding Makerere University‘s reputation as a centre of research excellence.

Prof. Tonny Oyana. Closing Ceremony of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 24th July 2026, MakSPH Auditorium, Kampala Uganda, East Africa.
Prof. Tonny Oyana.

He therefore thanked UNCST for promoting responsible conduct of research and strengthening ethical review systems in Uganda through facilitating trainings for RECs in GRRP and other critical areas such as Good Clinical Practice (GCP). He equally commended the Directorate of Research, Innovation and Partnerships (DRIP) led by Prof. Robert Wamala for organising the training, which continues to strengthen research governance structures across the University.

Incorporate RECs in Governance Structures

Presiding over the certificate award ceremony, the Deputy Executive Secretary UNCST, Dr. Martin Patrick Ongol congratulated all participants upon braving the three days of training despite their busy academic and research schedules. He equally commended Prof. Robert Wamala for ensuring that RECs at Makerere receive regular training and accreditation as mandated by governing procedures.

Dr. Martin Patrick Ongol (R) presents a certificate to Prof. Ruth Nsibirano (L). Closing Ceremony of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 24th July 2026, MakSPH Auditorium, Kampala Uganda, East Africa.
Dr. Martin Patrick Ongol (R) presents a certificate to Prof. Ruth Nsibirano (L).

In the same breath he noted that RECs are key to ensuring that institutions conduct credible research and therefore ought not to be kept at the periphery of governance. “We would like to see that Research Ethics Committees get incorporated into governance and management structures of Makerere University – not like ad-hoc or adjunct entities within the ecosystem.”

Dr. Ongol equally called upon researchers and proposal writers in the room to ensure that issues of ethics are adequately budgeted for in the studies. “When it comes to participant compensation, we sometimes hit a snag,” he cited. He equally called upon members of RECs to ensure that issues of documentation are adequately addressed. “80% of noncompliance issues observed by UNCST are due to improper, missing or poorly handled documentation, and one of the ways of improving is through continuous engagement and we hope that we shall get there” he added.

DRIP and National Accreditation Committee Laud RECs

Prof. Robert Wamala whose Directorate of Research, Innovation and Partnerships is at the heart of coordinating training with UNCST commended members of RECs, many of whom hold the ranks of Professors, Associate Professors and Senior Lecturers for sacrificing time to complete the GRRP Training. He reiterated that RECs are at the heart of ensuring that Makerere‘s research, particularly that involving human participants, meets national and international standards through harmonised ethical review approaches.

Dr. Martin Patrick Ongol (C) presents a certificate to Prof. Jesca Nakavuma (L) as Prof. Robert Wamala (R) witnesses. Closing Ceremony of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 24th July 2026, MakSPH Auditorium, Kampala Uganda, East Africa.
Dr. Martin Patrick Ongol (C) presents a certificate to Prof. Jesca Nakavuma (L) as Prof. Robert Wamala (R) witnesses.

Adding her voice, Prof. Sylvia Angubua Baluka, a member of the UNCST National Accreditation Committee noted that in addition to RECs, Institutional Animal Care and Use Committees play an important role in safeguarding the lives of animals that we depend on for food.

“I would therefore like to appreciate all Chairpersons and Members of Committees that are here; you are doing a good job and based on our site monitoring visits, we can address gaps in monitoring the research protocols you approve so as to have more impactful work and outputs that are more compliant with the ethical approval given” she added.

Prof. Sylvia Angubua Baluka. Closing Ceremony of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 24th July 2026, MakSPH Auditorium, Kampala Uganda, East Africa.
Prof. Sylvia Angubua Baluka.

RECs at a glance

A total of 95 members of RECs took part in the GRRP Training as broken down below.

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Uganda Strengthens Research Ethics Oversight as Makerere and UNCST Equip Ethics Committees for Emerging Scientific Challenges

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Participants pose for a group photo on Day One of the Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs). Day one of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 22nd July 2026, Senate Building, Kampala Uganda, East Africa.

By Moses Lutaaya

Kampala, Uganda — July 22, 2026

Uganda’s research sector is preparing for a new era of scientific advancement as emerging fields such as artificial intelligence, genomics, digital health; big data analytics and international research collaborations continue to transform the landscape of scientific inquiry. However, experts have emphasized that these developments must be matched with stronger ethical oversight mechanisms to protect research participants, maintain scientific credibility and preserve public trust.

The call was made during the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions. The training was organized by the Directorate of Research, Innovations and Partnerships at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST) to strengthen research governance and enhance ethical review practices.

Speaking at the official opening of the course, Prof. Robert Wamala, Makerere University’s Director of Research, Innovation and Partnerships, said ethical oversight remains central to achieving quality research that contributes to national development.

Prof. Wamala said Makerere University remains committed to producing research that addresses Uganda’s priorities while contributing to regional and global scientific advancement. However, he cautioned that research excellence cannot exist without strong ethical safeguards.

“Every research project involving human participants carries with it a profound responsibility to uphold the dignity, rights, safety and well-being of those who make research possible,” Prof. Wamala said.

Prof. Robert Wamala. High-level workshop of regulators, academic leaders, and research ethics committees focused on improving coordination, efficiency, and accountability in research oversight, 19th March 2026, Conference Room, School of Business, CoBAMS, Makerere University, Kampala Uganda, East Africa.
Prof. Robert Wamala. File Photo.

He described Research Ethics Committees as critical pillars of Makerere’s research ecosystem, emphasizing that their role extends beyond regulatory compliance to protecting scientific credibility and maintaining public confidence.

“The quality, consistency, independence and timeliness of ethical review directly influence the quality of research produced by our institution and the confidence that participants, funders, collaborators and society place in our work,” he said.

Prof. Wamala observed that emerging fields such as artificial intelligence, genomics, digital health, big data analytics and cross-border research collaborations have introduced new ethical questions requiring continuous learning and adaptation.

He said modern ethical oversight demands more than simply following regulations. “It requires critical thinking, sound judgment, an appreciation of emerging technologies and strict adherence to internationally accepted standards of ethical review,” he said.

He noted that the GRRP Course provides an opportunity to harmonize ethical review approaches across Makerere’s Research Ethics Committees, improve institutional capacity and ensure that research involving human participants meets national and international standards.

Prof. Wamala also commended UNCST for its continued partnership with Makerere University in strengthening research governance, describing the collaboration as a reflection of a shared commitment to fostering a research environment that is ethical, responsible, innovative and internationally competitive.

Relatedly, Dr. Hellen Opolot, the Assistant Executive Secretary and Head of the Directorate of Research Management and Quality Assurance at UNCST, called on Research Ethics Committees to continuously strengthen their capacity as Uganda’s research environment becomes increasingly complex.

Dr. Opolot said scientific progress presents immense opportunities but also introduces new ethical, legal and regulatory challenges that require regulators and ethics committees to remain ahead of emerging trends.

She noted that research in Uganda is rapidly expanding, driven by developments in artificial intelligence, genomics, digital health, social and behavioral sciences and multinational collaborative studies.

“As REC members, your role extends beyond reviewing research protocols. You are responsible for safeguarding the rights, dignity and welfare of research participants,” Dr. Opolot emphasized.

Dr. Hellen Opolot. Day one of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 22nd July 2026, Senate Building, Kampala Uganda, East Africa.
Dr. Hellen Opolot.

She commended the organizers, particularly Professor Wamala for their continued commitment to strengthening research governance through capacity-building initiatives targeting Research Ethics Committees, students and researchers.

“I want to express my sincere appreciation to Professor Wamala for continuously inviting me to these meetings and for organizing important capacity-building programmes, not only for Research Ethics Committees but also for students,” she said.

Dr. Opolot encouraged participants to actively engage in the training, share experiences and develop practical approaches to addressing ethical challenges, noting that many issues facing researchers and regulators require collaboration and informed judgment.

She expressed confidence that the knowledge gained from the training would improve ethical review processes, strengthen post-approval monitoring and promote a culture of research integrity across Uganda.

Prof. Fredrick Nelson Nakwagala, the Chairperson of the Accreditation Committee for Research Ethics in Uganda at UNCST, said the training was aimed at equipping Research Ethics Committees with the skills required to protect human participants and improve research quality.

“The main function of this meeting is to build the capacity of Research Ethics Committees at Makerere University to perform their responsibility of protecting human subjects in research,” Prof. Nakwagala said.

He explained that continuous training remains necessary because ethical standards evolve alongside changes in science and technology.

“Ethics keeps changing because circumstances change. We now have artificial intelligence, mathematical modelling and complex study designs that were not known before. There are also new international and national guidelines on how to protect human participants who volunteer in research,” he said.

Prof. Nakwagala emphasized that Research Ethics Committees play a broader role than approving research proposals. He said they also monitor approved studies to ensure compliance with regulations, scientific standards and legal requirements.

“They monitor approved studies to ensure they are conducted within applicable regulations, scientific standards and the law. This improves both the quality of research proposals and the quality of research implementation,” he said.

He warned that unethical research practices such as plagiarism, fabrication of participants and falsification of data could undermine national development efforts, especially when research findings influence public policy.

A section of participants attending the course. Day one of the three-day Good Research Regulatory Practice (GRRP) Course for members of Research Ethics Committees (RECs) from Makerere University and other institutions organized by the Directorate of Research, Innovations and Partnerships (DRIP) at Makerere University in partnership with the Uganda National Council for Science and Technology (UNCST), 22nd July 2026, Senate Building, Kampala Uganda, East Africa.
A section of participants attending the course.

“You don’t want research products from scientists who are fraudulent, who fabricate participants or falsify data,” he said. “Research Ethics Committees ensure research is what it claims to be and that the process gives confidence in the results.”

Prof. Nakwagala added that ethics committees play an important role in mentoring postgraduate students by providing a framework that enables them to conduct credible and scientifically sound research.

He linked strong research ethics to Uganda’s development ambitions under the National Development Plan IV, noting that science, technology and innovation are increasingly important in sectors such as agriculture, health, infrastructure, housing and environmental sustainability.

“Ethical oversight is critical in balancing the risks and benefits of development initiatives,” he said.

Addressing concerns about delays in postgraduate research approvals, Prof. Nakwagala said new review timelines introduced by UNCST are expected to improve efficiency while maintaining quality.

“We believe that within a week, most student protocols should receive approval. Only larger studies such as clinical trials require more rigorous review, but even these should not exceed 60 days,” he said.

Day One of GRRP Course Brings Together Experts and Research Ethics Practitioners

Day one of the Good Research Regulatory Practice Course was facilitated by Ms. Irene Semakula Suryani, Dr. Fredrick Nelson Nakwagala, Dr. Robert Sekubugu, Prof. Noah Kiwanuka and Ms. Gladys Nakalema, who guided participants through key areas of ethical review, research governance, regulatory standards and best practices for strengthening Research Ethics Committees.

The training attracted members from various academic units and institutions, including 16 participants from the College of Health Sciences, 5 from the School of Social Sciences, 15 from the College of Agricultural and Environmental Sciences (CAES), 23 from the School of Public Health, 23 from the School of Medicine, 19 from the School of Biomedical Sciences and 5 from the College of Veterinary Medicine and Animal Resources (COVAB).

Research Ethics Committee Leaders Attend Capacity-Building Training

The course also brought together chairpersons of Research Ethics Committees from different schools and colleges who participated in strengthening ethical review systems at Makerere University and beyond. Among those in attendance were chairpersons of the different RECs including Prof. Stella Neema from the School of Social Sciences, Dr. Paul Kutyabami from the College of Health Sciences, and Dr. Joseph Kagagi from the School of Public Health, among other REC leaders.

The participation of REC chairpersons underscored the importance of institutional leadership in promoting responsible research practices, improving review efficiency and ensuring that scientific advancement is guided by integrity, accountability and respect for human dignity.

The GRRP training, running from July 22 to 24, 2026, is part of ongoing efforts by Makerere University and UNCST to strengthen Uganda’s research governance system and ensure that scientific progress is built on ethical foundations.

Mak Editor

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