A screenshot of the DESAT research dissemination by Makerere University researchers on 16th June 2021 showing; Vernomia amygdalina (Muluswa), Warbugia ugandensis (Atiko) and Abrus precatorius (Osito) species used to treat malaria in Tororo district, Eastern Uganda.
A study funded by the Government of Uganda through the Makerere UniversityResearch and Innovations Fund (Mak-RIF) in the College of Agricultural and Environmental Sciences (CAES) has found that prolonged use of herbal medicines affects body organs.
Researchers recommend that traditional medicines should not be used for more than 14 days. The need for regulation and strengthening quality assurance along the value chain to reduce risks associated with the use of herbal medicines has been emphasized.
This was revealed during the virtual research dissemination workshop of the RIF 1/CAES/025 project titled, “Development of Safe and Efficacious Anti-Malarial drug from Traditional Medicine (DESAT)” on 16th June 2021.
DESAT is an interdisciplinary and multi-institutional research project led by Prof. John Steven Tabuti – an ethnobotanist from Makerere University’s Department of Environmental Management in the College of Agricultural and Environmental Sciences.
Co investigators are Dr. Alice Nabatanzi from the College of Natural Sciences (CoNAS), Cissy Nambejja, Senior Research Officer, Ministry of Health, Natural Chemotherapeutics Research institute, Prof. Paul Waako, Vice Chancellor Busitema University and Micheal R Mutyaba, Manager Traditional and Complementary Medicine, National Drug Authority. Other team members from CoNAS are Stanley Ofwono (Laboratory Technician), Diana Sitenda (Student) and Olivia Maganyi (Para taxonomist).
Presenting the project results, the Principal Investigator Prof. John Steven Tabuti said the project undertook research in Tororo district and gathered data to determine the commonly used plant material for the treatment of malaria and the safety profiles of selected species.
“We found through this study that the three species that we investigated were reasonably safe to use in a period of 14 days. Beyond 14 days, we have observed some negative impacts on the organs of the animals.
One of the effects was on the kidney, another, was a clot in the stomach, and there was also some ulcers in the stomach, and death of some cells in the liver. This suggests that these traditional herbs are not safe. Some of the results have not yet come back, which should tell us if we should be very conscious.
*****Funded by the Danish Ministry of Foreign Affairs through DANIDA, the Healthy Soy Project seeks to develop sustainable, affordable, and nutritious soy-based food solutions to help combat stunting in Uganda and other climate-vulnerable regions. The Project inception meeting was held on 15th August 2025 at CAES, Makerere University.
Overview
Child malnutrition remains one of the most pressing public health challenges worldwide. According to the World Health Organization (WHO), more than 148 million children under the age of five were affected by stunting in 2023, a condition caused by chronic under-nutrition that impairs both physical and cognitive development. The United Nations Sustainable Development Goal 2 aims to end all forms of malnutrition by 2030, but climate change, rising food insecurity, and deepening inequality are making this goal increasingly difficult to achieve.
The Dean, School of Agricultural Sciences, Dr John Baptist Tumuhairwe delivering welcome remarks behalf of the Principal of CAES, Makerere University.
Expert reports indicate that as the global climate crisis accelerates, its ripple effects are being felt most acutely in the Global South. Prolonged droughts, erratic rainfall, and frequent natural disasters are reducing crop yields, diminishing nutrient density in food, and driving up food prices. For smallholder farmers, who form the backbone of food production in many developing countries, these changes are devastating. Without the resources to invest in irrigation or climate-adaptive technologies, they are hit hardest by agricultural losses.
The burden of climate-induced food insecurity and malnutrition is not shared equally. Children are particularly vulnerable, as their growth demands a consistent intake of high-quality nutrients. Women, meanwhile, are doubly impacted. They are often both food producers and the primary caregivers responsible for child nutrition. These gendered and generational inequalities are deepening as food systems falter under environmental stress.
Some of the project partners that participated in the inception meeting.
Stunting and the Need for High-Quality Protein
Stunting in children is one of the most visible forms of malnutrition. Once it occurs, reversing it is challenging, though not impossible. For children affected by stunting to catch up in growth, their diets must include high-quality proteins, which are essential for muscle and tissue development.
Animal-source foods such as milk, eggs, and meat provide proteins with the highest biological value. However, in low-income settings, these foods are often prohibitively expensive or unavailable. Soybeans offer a promising alternative – they are a plant-based source of relatively high-quality protein, widely grown and consumed in many parts of the world. However, soy is not without limitations. Its protein bioavailability can be reduced by natural compounds known as anti-nutrients, which inhibit digestion and absorption.
Prof. Benedikte Grenov, the Principal Investigator, delivered a comprehensive overview of the project.
The Healthy Soy Project: A Science-Based Solution for Sustainable Nutrition
In response to this challenge, Makerere University, in collaboration with partners and with funding from the Danish Ministry of Foreign Affairs through the Danish International Development Agency (DANIDA) has launched an innovative research project titled Climate-resilient soybean for improved growth and health of children in Uganda (Healthy Soy). This multi-year project seeks to develop sustainable, affordable, and nutritious soy-based food solutions to help combat stunting in Uganda and other climate-vulnerable regions. The University of Copenhagen, Denmark is leading the project, with Makerere University and RECO Industries Limited as partners. The overall PI of the Project is Prof. Benedikte Grenov from the University of Copenhagen. At Makerere University, the project is coordinated by Prof. Phinehas Tukamuhabwa. Other project members include Assoc. Prof. Nanna Roos and Prof. Inge Tetens from the University of Copenhagen; Assoc. Prof. Dorothy Nakimbugwe and Assoc. Prof. Ezekiel Mupere from Makerere University; Mr. Alex Kisembo from RECO Industries Limited; and Prof. Daniel Tomé from Université Paris-Saclay, France.
Prof. Phinehas Tukamuhabwa, Coordinator of the Healthy Soy Project sharing his views at the meeting.
The Healthy Soy project is structured around four key work packages
Researchers will identify and develop soybean strains that are both resilient to climate stressors and contain high levels of protein with reduced anti-nutrient content, making them more suitable for vulnerable populations.
WP2 – Enhancing Protein Bioavailability through Food Processing
Advanced food processing technologies will be employed to reduce anti-nutrient levels and improve the bioavailability of soy protein. The project will also evaluate how effectively soy protein supports catch-up growth in children affected by stunting.
Dr. Jenipher Bisikwa, Prof. John Muyonga, and Prof. Benedikte Grenov following the proceedings of the meeting.
WP3 – Developing Local Soy-Based Food Supplements
Working closely with local communities and food producers, the project will design and test new soy-based supplements tailored to local dietary habits. These products will be tested for their impact on child health and growth.
WP4 – Building Local Research Capacity and Sharing Knowledge
Capacity-building is a core element of Healthy Soy. The project will invest in training Ugandan researchers, strengthening local institutions, and disseminating findings to farmers, policymakers, health professionals, and other stakeholders across the region. At Makerere University, the project is supporting 3 PhD fellows namely: Ms. Nashim Nassanga from the Department of Crop Science and Horticulture, Mr. Amos Asiimwe from the Department of Food Technology and nutrition, and Ms. Prudence Ainomugisha from the College of Health Sciences. Ms. Nassanga will focus on identifying climate-smart soybean breeding lines for adaptability and farmers’ acceptability under severe climate conditions in Eastern, Northern, and Western Uganda; Mr. Asiimwe will develop soybean processing protocols to reduce anti-nutrients, improve soy protein bioavailability, and estimate its potential to support catch-up growth in children with stunting; and Prudence Ainomugisha will examine the effects of locally produced soy-based LNS on the growth and health of children with stunting.
Mr. Ephraim Nuwamanya shared insights into the ongoing research activities MAKCSID, particularly focused on developing climate-resilient soybean varieties.
The Healthy Soy Project Inception Meeting
On 15th August 2025, the project team held an inception meeting to discuss strategies for its implementation. The session brought together representatives from all partner institutions who shared a detailed overview of their respective roles, and expected contributions to the initiative. The discussions focused on aligning stakeholder roles, clarifying project objectives, and ensuring a coordinated approach to execution.
During the meeting, Prof. Benedikte Grenov, the Principal Investigator, delivered a comprehensive overview of the project. She emphasized the collaborative nature of the project and highlighted the importance of each stakeholder’s role in achieving the intended outcomes. Her presentation set the stage for subsequent contributions from each partner institution, outlining their respective roles and planned activities within the project.
Mr. Alex Kisembo from RECO Industries Limited shared their experience in soybean processing and outlined their planned contribution to the project’s product development streams.
Dr Mildred Ochwo Ssemakula, Prof. John Muyonga, and Dr Robert Mugabi from Makerere University Departments of Crop Science and Horticulture, and Food Technology and Nutrition respectively, briefed the team on their (Departments’) role in the soybean value chain, while Dr Ephraim Nuwamanya from the Makerere University Centre for Soybean Improvement and Development (MAKCSID) shared insights into their ongoing research activities, particularly focused on developing climate-resilient soybean varieties and how these efforts align with the goals of the Healthy Soy Project. The meeting also featured a presentation on the activities of the Child Health Development Centre (CHDC) and its role in the project. Based within the College of Health Sciences at Makerere University, the CHDC will support the training of a full-time PhD fellow who will coordinate and implement a randomized controlled clinical trial (RCT) involving 300 children affected by stunting.
The representative from RECO Industries Limited, Mr. Alex Kisembo shared their experience in soybean processing and outlined their planned contribution to the project’s product development streams. Additionally, the integration of the Healthy Soy initiative into the national nutrition programming was discussed, with an emphasis on aligning it with priority areas within the health sector. The roles of the Ministry of Agriculture, Animal Industry and Fisheries (MAAIF) and the Uganda National Bureau of Standards (UNBS) were also presented, particularly focusing on their support for soybean development through policy formulation, quality assurance, and regulatory processes, as well as their planned contributions to the project’s implementation.
Prof. John Muyonga delivering a presentation on the expected output of the Healthy Soy Food Science research.
Prof. Charles Masembe briefed participants on the reporting and accountability procedures of the Makerere University Grants Administration and Management Support Unit (GAMSU).
The meeting was moderated by Prof. Phinehas Tukamuhabwa and Dr Jenipher Bisikwa from the Department of Crop Science and Horticulture, College of Agricultural and Environmental Sciences (CAES), Makerere University.
Prof. Charles Masembe briefing the team about the Makerere University Grants Administration and Management Support Unit reporting and accountability processes.Dr. Mildred Ochwo Ssemakula addressing the team on the operations of the Crop Science and Horticulture Department at Makerere University.A representative from the Uganda National Bureau of Standards presenting about the quality assurance processes.The Assistant Commissioner in charge of Seed Inspection and Certification at MAAIF, Dr Mary Teddy Asio delivering a presentation on the operations of the Ministry.The PhD students supported by the Project, Mr Amos Asiimwe, Ms. Nashim Nassanga, and Ms. Prudence Ainomugisha with Prof. Benedikte Grenov and her colleague from the University of Copenhagen.
First Year students admitted to the College of Agricultural and Environmental Sciences (CAES), Makerere University have been cautioned to approach University life with clear purpose and focus.
Speaking at the College orientation on 7th August 2025, CAES Principal, Prof. Gorettie Nabanoga urged the students to set goals from the start of their academic journey and to work diligently to achieve them. “University life offers tremendous opportunities, but it also comes with freedoms that can easily lead you off course,” she warned. “Set your academic and personal goals early – understand why you are here, what you want to accomplish, and how you intend to achieve it.”
She encouraged the students to take full advantage of the academic resources, mentorship programmes, and practical training opportunities offered by the College, while also warning them about the distractions that often derail student focus. “Social life is part of the experience, but never let it overshadow your purpose.”
The Principal, Prof. Gorettie Nabanoga delivering her remarks at the orientation ceremony.
Prof. Nabanoga highlighted the college’s commitment to nurturing future leaders in agriculture, environmental sciences, food technology, and related disciplines. “You join CAES at a critical time when global challenges like climate change, food security, and sustainability demand your innovation and passion. At CAES, we are committed to empowering our students to become job creators and leaders in the agricultural sector.”
The event featured addresses from other key college and University administrators, academic leaders, and representatives from the student guild, who all echoed the importance of intentionality, discipline, and resilience throughout the university journey.
CAES freshers at the orientation ceremony held on 7th August 2025 at the College premises.
In his remarks, the Deputy Principal of the College, Prof. Yazidhi Bamutaze welcomed the First Year students, commending them for joining a College committed to academic excellence and societal impact. “You are fortunate to be part of a college that has carefully designed its academic programmes to align with real-world development pathways,” he said. “Our core mission revolves around the production of knowledge that responds to both local and global needs.”
He emphasized the College’s pivotal role in nurturing critical human capital, likening it to a factory that refines raw talent into highly skilled graduates. “We see ourselves as a knowledge production hub, taking in inputs in the form of students and transforming them into outputs ready to meet the demands of the competitive global market.”
Prof. Namaalwa briefing students about the Safeguarding Policy. She warned against all forms of discrimination at the University.
Prof. Bamutaze reiterated the College’s commitment to ensuring that every student receives the support, training, and exposure needed to thrive both academically and professionally. “We are dedicated to ensuring that the entire academic journey is seamless and impactful.
During the orientation programme, the Deans of the schools at CAES introduced the students to the academic programmes offered within their units. In addition to the school-specific briefings, the students received information about the University’s academic structure and operations. This included guidance on essential processes such as registration and examination procedures. They were also introduced to a wide range of support services and institutional policies designed to enhance their academic experience and overall well-being. These included the University’s ICT support systems, library resources, the structure and timelines for fee payments, and key regulatory frameworks such as the Anti-Sexual Harassment Policy and the Safeguarding Policy.
The Deputy Principal of CAES, Prof. Yazidhi Bamutaze addressing the freshers.
Furthermore, students were informed about the availability of counselling and guidance services, which play a vital role in supporting mental health and personal development. The session also emphasized the University’s commitment to student welfare, aiming to foster a safe, inclusive, and supportive learning environments to stand out wherever they go.
Briefing students on the University’s Safeguarding Policy, Prof. Justine Namaalwa emphasized the importance of creating an inclusive and respectful learning environment, strongly cautioning against all forms of discrimination, particularly against persons with disabilities. She reaffirmed the University’s commitment to protecting the dignity, rights, and well-being of every individual, in line with the safeguarding principles of equity, non-discrimination, and accountability.
Mr Bedan Ssekandi addressing the freshers on behalf of the student leadership at CAES.
As an integral component of the orientation programme, the students toured the college facilities to familiarise with the various resources and spaces available, including classrooms, laboratories, the library, recreational areas, and administrative offices.
The Principal of the College of Agricultural and Environmental Sciences (CAES) at Makerere University, Prof. Gorettie Nabonoga has urged student innovators to safeguard their intellectual property rights. Speaking at the end-of-recess exhibition organized by the School of Food Technology, Nutrition, and Biosystems Engineering to showcase student-led innovations, she cautioned students about the risks of intellectual theft.
The Principal of CAES, Prof. Gorettie Nabanoga addressing participants. She urged student innovators to safeguard their intellectual property rights.
“It is essential to take proactive measures to protect your ideas,” Prof. Nabanoga emphasized. “If you have developed something original and useful, make sure to register your innovation. Intellectual property rights are essential for securing the recognition and rewards you deserve. Remember, plagiarism is not just an academic issue – it affects business and innovation.”
She commended the students for their creativity and responsiveness to local market needs.
Some of the staff, students, and stakeholders that participated in the activity.
Held at the School premises on 24th July 2025, the exhibition, attended by students, staff and industry stakeholders, featured a wide array of student-created products, including solar-dried fruit snacks, low-cost grain sorters, biodegradable packaging from crop waste, and nutrient-rich baked goods targeting malnutrition. Students presented petri dishes from a microbial analysis of street-vended mangoes sold around Makerere University, revealing that the fruits may be unhygienic and potentially unsafe for consumption. They also demonstrated a low-cost water purification technology designed for cleaning and reusing wastewater from pilot or food processing plants. The system utilizes moringa seed powder, charcoal, sand, stones, and cotton wool to produce clean, clear water suitable for reuse, such as for cleaning. Additionally, the students showcased the use of activated charcoal and beeswax to extend the shelf life of fruits like bananas and passion fruit. These innovative, low-cost technologies have the potential to be further developed and adopted by farmers and traders to reduce postharvest losses. The innovations were developed during a 10-week recess programme that immerses students in hands-on fieldwork, research, and product development.
Other products made by students included tomato ketchup and solar-dried bananas.
In his remarks, Prof. Ivan Muzira Mukisa, Head, Department of Food Technology and Nutrition, encouraged the students to envision their projects beyond the academic realm and focus on transforming them into viable commercial enterprises. “The future of agriculture lies in innovation. The students have demonstrated the potential to solve pressing challenges, create jobs, and build businesses. Their work shouldn’t end at the exhibition. It should continue into the market,” he said.
The Principal of CAES, Prof. Gorettie Nabanoga, together with the Deputy Principal, Prof. Yazidhi Bamutaze, the Head, Department of Food Technology and Nutrition, Prof. Ivan Muzira Mukisa, and some of the stakeholders touring the exhibition stalls.
Dr. Stella Byakika, Coordinator of the recess programme, emphasized the importance of experiential learning in shaping Uganda’s next generation of agricultural leaders. “This programme goes beyond fulfilling academic requirements. It is a practical training platform where students apply their knowledge to real-world problems. We are preparing them not just to graduate, but to lead in transforming Uganda’s agricultural and agro-processing sectors,” she explained.
Prof. Yazidhi Bamutaze, Deputy Principal of CAES, sharing insights on the significance of the Field Attachment Programme.
On behalf of her classmates, Ms. Ndegema Daphine, a Third Year student of Human Nutrition, expressed gratitude for the hands-on experience gained during their internship. “During the recess term, we had the opportunity to work directly with children suffering from severe acute malnutrition, including cases with edema and dermatosis. We participated in both inpatient and outpatient therapeutic care, which gave us a real-world perspective on the clinical management of these conditions. Unlike in the classroom, where we only study such cases theoretically, the internship allowed us to witness the treatment process a nd see patients recover first-hand. With guidance from our supervisors, we were able to conduct clinical assessments for malnutrition and edema, as well as evaluate dietary needs. We also put into practice what we had learned in our communication skills course by delivering nutrition education sessions, helping patients and caregivers understand the importance of proper nutrition in recovery and long-term health.”
A student showcasing a package of solar-dried mangoes, one of the products they worked on during internship.
Delivering her remarks, the Dean of the School of Food Technology, Nutrition, and Biosystems Engineering (SFTNB), Dr Julia Kigozi appreciated the University and College Administration for their unwavering support towards students’ projects and academic endeavours. She commended the students for their creativity and commitment to excellence in their work. “Our goal is to nurture and produce well-rounded graduates who not only excel academically but also embody an entrepreneurial mind-set, a strong work ethic, a deep sense of social responsibility, and respect for authority. These values are essential as they prepare to make meaningful contributions to society and the broader global community.”
Students presenting petri dishes from a microbial analysis of street-vended mangoes sold around Makerere University, revealing potential hygiene concerns and safety risks. The Dean SFTNB, Dr Julia Kigozi appreciated the University and College Administration for their unwavering support towards students’ projects and academic endeavours. She commended the students for their creativity and commitment to excellence in their work.
Held annually, the recess programme equips students with field experience through community-based projects, agribusiness development, and food innovation. The culminating exhibition serves as a platform for feedback, exposure, and networking with industry professionals.
More photos from the exhibition
Some of the students with Prof. Yusuf Byaruhanga.Prof. Ivan Muzira Mukisa, Head, Department of Food Technology and Nutrition, encouraged the students to envision their projects beyond the academic realm and focus on transforming them into viable commercial enterprises.One of the products showcased by the students, Red Harvest Ketchup.The students with the College leaders and their supervisors at the exhibition.