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VC Statement to The Press: Tuesday 21st April 2020

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Good morning members of the Press.

I welcome you all to this press conference conducted via Zoom in response to the COVID-19 lockdown. I hope you are all observing the guidelines given by the World Health Organisation and different Government Departments and Agencies to stay safe. Obviously it is difficult to convince you members of the press to stay home, but please do everything possible to stay safe. There have been many questions regarding the role of universities in the fight against COVID-19. Today we want to share with you what Makerere University is doing about COVID-19.

Makerere University was closed on 20th March 2020 following a presidential directive in light of the COVID-19 pandemic. All students and staff were sent home immediately, except very few international students, who failed to get means of going home, whom we are looking after on campus.

Makerere University has a long tradition of responding to health emergencies and epidemics. We were at theforefront of the response to HIV/Aids and Ebola and our contribution in both cases is known the world over. We have built enormous capacity at our College of Health sciences to respond to emerging diseases, including the COVID-19 pandemic. Our 350 members of staff at the College of Health Sciences work very closely with the Ministry of Health.All of these continue to offer critical services to non-COVID illnesses, COVID19 national task force, clinical management for patients with COVID 19, as well as clinical research on the evolving clinical presentations of the COVID19 disease.

RESPONSE TO COVID-19

In Uganda, the first case of COVID was reported on 21stMarch 2020 and the numbers have since grown to 55 within one month. The Minister of Health established a 17-member multidisciplinaryscientific advisory committee composed of experienced public health, clinical, biomedical, social andbehavioural scientists to advise the Ministry on the overall strategy to ensure an evidence-based strategy and implementation of the COVID response in Uganda. The majority of the members of thiscommittee are from Makerere University. The committee has extensively reviewed the globalliterature to inform the Ugandan policy and has also similarly assembled high priority evidence gapsfor which local data is needed to urgently inform the improvements in the COVID prevention and management in Uganda. The questions and priority interventions include development of new rapidtest diagnostics, to alleviate the anticipated severe shortage of test kits, which has been a majorchallenge globally. Other questions include tracking of the immunological response in relation to new treatment options based on plasma for COVID patients who have recovered as well as development of HERD Immunity to protect the communities from future resurgence of COVID.

Other questionsrevolve around enhanced treatments to reduce the severity of COVID disease and the need for moresophisticated intensive care, given the limited intensive care capacity in Uganda and the African region. The team has also identified the need to explore the socio-economic and health systemimpact of COVID in Uganda, to inform broader mitigation strategies. Below is a list of the priorityquestions:

  1. Development of a rapid diagnostic test for CoVID19
  2. Validation of other non-WHO accredited tests for CoVID19
  3. Studies of HERD immunity/Immune response andimplications for future prevention of COVID recurrence as well as clinical management
  4. Chloroquine/Hydroxychloroquine and other treatments
  5. Modelling of COVID19 epidemic in Uganda to inform planning and intervention mix over time
  6. Environmental sampling for public health risk evaluation
  7. Supporting the NIH biobank to acquire and store biological specimen for CoVID19
  8. Tracking health service utilization and COVID19 impacton health systems
  9. Sequencing of the SARS-CoV2 isolates among Ugandan CoVID19 patients
  10. Duration of viral shedding and Infectivity following recovery
  11. Effect of the Uganda COVID-19 treatment protocol on outcomes and associated factors
  12. Chloroquine for Prevention of Coronavirus Disease (COVID-19) amongst healthcare workersinvolved in COVID patient care
  13. Hydroxychloroquine vs Chloroquine for Post Exposure Prophylaxis for Coronavirus Disease(COVID-19) amongst Ugandans exposed couple with viral loads.
  14. Efficacy and Safety of Corticosteroids in severe COVID-19 related pneumonia
  15. Hydroxychloroquine/AzithromAzithromycin vs Chloroquine alone for Treatment for Severe COVID-19 Pulmonary Infection.

 

OTHER RESPONSES/INNOVATIONS

Makerere University researchers have responded to the COVID-19 pandemic with innovations to address the challenges I have mentioned above. The innovations include the following:

  1. A rapid testing kit under development by a team led by Dr. MisakiWayengera. This kit should enable rapid testing for coronavirus and considerably lower the cost of testing currently standing at USD 65, which is obviously prohibitive for developing countries like Uganda.

The problem

  • Diagnosis is a key strategy in pandemic control, enabling early detection of those infection and their isolation for treatment
  • In the context of the on-going COVID19 pandemic, diagnosis has been problematic due to the global scarcity of the existing WHO approved test kits
  • Moreover, the existing WHO approved kits for CoVID19 are premised on RT-PCR—detecting viral RNA. RT-PCR is itself an expensive platform (costing over US$65 per kit), requires a laboratory, demands technical expertise, and takes long (4-6 hours) to yield results.
  • Thus, it is not amenable for point of care (POC) deployment in remote equatorial African settings, most without laboratory capacity

What we are doing

  • Our group at MakCHS has over the past 15 years build extensive expertise, experience and eco-systems across the academia, industry and public private partnerships for R & D of pathogen diagnostics
  • We are developing an affordable (costing < US$1), easy to use (requiring minimal expertise, user guide), rapid (yielding results within 2-5 minutes) POC test platform for COVID19 suited for use within remote equatorial African settings
  • The swab-tube dipstick agglutination (STDS-AgX) SARS-CoV2 antigen test will utilize the nasopharyngeal sample collection swab, which is placed back into its tube containing reagents that detect the virus surface protein. On shaking, a positive result will be visualized as formation of particles (equivalent to what is seen when clear milk, goes bad)
  • In addition, we shall develop two lateral flow test (LFT) platforms for detecting host-specific antibody responses against CoVID19 (IgM and IgG)

Use cases

  • Detection of COVID19 cases within epidemic/pandemic settings (STDS-AgX COVID19 Ag test)
  • Screening of travelers for COVID19 (either STDS-AgX COVID19 Ag  test or IgM LFA)
  • Detection of asymptomatic COVID19 (STDS-AgX COVID Ag test and IgM LFA)
  • Sero-prevalence studies to determine previous exposure (IgG LFA)

Potential impact:

These home-grown assay platforms will enable Uganda and other African settings cost-effectively respond to the COVID19 pandemic. This particularly as the pandemic enters the exponential phase in many countries when many cases will emerge, and yet tests are scarce on the global scene

Time-lines

  • Antibody (IgM and IgG) LFA (end of May, 2020)
  • 1st STDS-AgX COVID19 (June 2020)
  1. The Epidemic Management Tent (EpiTent) developed by a team from the Resilient Africa Network (RAN), a project involving 16 universities in 11 african countries based in the School of Public Health and coordinated by Prof. Bazeyo. The EpiTent is used for isolation of patients with severe communicable diseases like Ebola and COVID-19 and it is approved by the USAID and the WHO;
  2. Development of a low-cost ventilator by a team involving researchers from the Resilient Africa Network, College of Engineering and Technology, College of Health Sciences and engineers from Kiira Motors Corporation.  The team successfully conducted an engineering test of the ventilator on 10th April 2020 and it is now undergoing various validation tests before applying to the National Drug Authority and other certifying agencies for use on patients. The ventilator will considerably lower the cost of this very important facility from the current cost on the open international market, which ranges between USD 25,000 and 60,000. Development of the ventilator, which will cost approximately USD 5,000 is expected to be completed in the next four to eight weeks;
  3. Makerere University Health Services with support from Case Western Reserve University has built capacity to perform PCR based (molecular) tests for COVID-19. They will be able to conduct 40,000 tests and they are finalizing the details for implementation;
  4. Makerere University is partnering with several local and international research institutions and universities in the search for solutions to the COVID-19 pandemic.

 

RESPONSES BY OTHER DISCIPLINES

Faculty from the Colleges of Health Sciences and Engineering, design, Art and Technology are at the forefront of responding to the pandemic. However, faculty from other disciplines are making a contribution too. Several of these faculty are making a contribution to raising awareness among the community and providing correct information where fake news has raised alarms like in the case of the claim that COVID-19 is caused by the 5G Technology. Management of a pandemic like COVID-19 cannot be achieved by health science alone, societal behavior is key, hence the role of humanities and social sciences and I am glad that faulty at Makerere University from various disciplines are making their contribution.

CONCLUSION

Let me end my remarks by thanking our faculty from the College of Health Sciences, who have joined the rest of the health workers in Uganda at the frontline in fighting the spread of COVID-19 disease. I also thank all our scientists who are looking for local solutions to the pandemic and we are glad to share any research results with the international community. Makerere is committed to contributing to knowledge creation and innovations for the good of humanity. We will continue along this path because this is what makes us a truly global university. I thank all of you members of the press for joining this conference. We will now take some questions, which our researchers will be happy to answer.

Mark Wamai

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Makerere University Pushes for Stronger Support for Research Ethics Committees amid Growing Research Demands

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Seated: Prof. Sarah Ssali (2nd L) and Prof. Robert Wamala (2nd R) with Chairpersons of Research Ethics Committees on 25th May 2026. High-level meeting between University Management and Chairpersons of Research Ethics Committees (RECs) held in the Vice Chancellor’s Boardroom, Makerere University Main building, Kampala Uganda, East Africa on May 25, 2026.

By Moses Lutaaya

Makerere University has intensified efforts to strengthen research governance and ethical oversight, with university leaders calling for greater institutional support for Research Ethics Committees (RECs), whose role has become increasingly central to the institution’s research-led agenda.

The call was made during a high-level meeting between University Management and Chairpersons of Research Ethics Committees held at the Vice Chancellor’s Boardroom at the Makerere University Main Building on May 25, 2026.

Opening the meeting, the Director of Research Innovations and Partnerships (DRIP), Prof. Robert Wamala, highlighted a number of operational and administrative challenges affecting the effectiveness of RECs at Makerere University.

Prof. Wamala observed that RECs continue to operate with gaps in institutional framework outlining their position within the university governance structure, a gap he said has affected institutional support and long-term sustainability.

According to Prof. Wamala, inadequate facilitation continues to affect the operations of several committees, especially in areas of staffing, administrative coordination, and remuneration for REC administrators.

Prof. Robert Wamala. High-level meeting between University Management and Chairpersons of Research Ethics Committees (RECs) held in the Vice Chancellor’s Boardroom, Makerere University Main building, Kampala Uganda, East Africa on May 25, 2026.
Prof. Robert Wamala.

He also pointed to challenges arising from new regulatory requirements governing the appointment of REC members, particularly the need for appointment letters to be authorized or signed by the Vice Chancellor.

Prof. Wamala further raised concern over the high cost of mandatory accreditation and training processes required by the Uganda National Council for Science and Technology (UNCST), especially the Good Research Regulatory Practice (GRRP) training undertaken every three years. “Payment for training is too high for individual RECs to cover,” he noted, adding that many committees are struggling to independently raise the money to undertake the training for all their members.

He also emphasized the need for stronger institutional monitoring systems to support timely submission of accreditation renewal applications, oversight of approved research activities, and coordination of REC operations across the university.

In her remarks, the Deputy Vice Chancellor in charge of Academic Affairs, Prof. Sarah Ssali, commended the growing contribution of RECs in advancing Makerere University’s research agenda and acknowledged the concerns raised by Prof. Wamala and committee members.

“There were not very many RECs,” Prof. Ssali said. “So now that we are 10, it is really impressive because it speaks to our cause for a research-led university.” She admitted that despite their importance, many RECs still operate outside the formal university establishment, making staffing and operational support difficult.

Prof. Sarah Ssali. High-level meeting between University Management and Chairpersons of Research Ethics Committees (RECs) held in the Vice Chancellor’s Boardroom, Makerere University Main building, Kampala Uganda, East Africa on May 25, 2026.
Prof. Sarah Ssali.

“The only challenge that I see is that they are not fully institutionalized. So it is upon units to start them or not to start them,” she explained. Prof. Ssali added that because RECs are not fully integrated into the public service structure of the university, recruiting and remunerating staff through conventional university systems remains complicated. “Hiring for them staff will be a little bit cumbersome because the university will say they are not part of our structure,” she said.

She nevertheless emphasized that university management recognizes the strategic importance of RECs in strengthening ethical research oversight and supporting Makerere’s position as a research-led institution. “RECs are doing a great job of furthering our strategic agenda of being a research-led university,” she noted.

Prof. Ssali explained that the growing reliance on institutional RECs by the Uganda National Council for Science and Technology demonstrates the trust placed in Makerere University’s ethical review systems.

Addressing concerns about the cost and frequency of mandatory training, Prof. Ssali acknowledged the financial burden on RECs but explained that many of the requirements are set by national regulators. “Many of the things you have raised are with National Council, they are not with us,” she said. “We can only pledge to lobby.”

To address logistical challenges associated with training senior academics, she proposed more flexible scheduling arrangements. “For a professor to give you a whole day is going to be a challenge,” she said. “Maybe you can do half days throughout the week.”

Prof. Ssali also encouraged colleges and schools to allocate part of their enhanced research budgets toward supporting REC activities, including staffing, training, and operational facilitation.

The High-Level Meeting in session. High-level meeting between University Management and Chairpersons of Research Ethics Committees (RECs) held in the Vice Chancellor’s Boardroom, Makerere University Main building, Kampala Uganda, East Africa on May 25, 2026.
The High-Level Meeting in session.

She suggested that colleges and schools hosting RECs should directly take responsibility for sustaining them. “For me, that’s the way out — to ensure that the colleges and schools that have RECs take them as their responsibility,” she noted.

The DVC-AA also addressed concerns related to intellectual property rights, Material Transfer Agreements (MTA), and the need for researchers to formally communicate scientific discoveries and innovations to the university to ensure institutional protection and benefit-sharing. “All you are saying is true, but it depends on you as researchers informing the institution that we have made this discovery,” she said.

Prof. Ssali reiterated Makerere University’s commitment to strengthening research governance systems and pledged continued engagement with both university management and national regulatory bodies to address the concerns raised by REC members. “Where they are, they enable research, publication and growth,” she said of the RECs. “Most importantly, they enable us to be ethical with the way we do our things.”

The meeting was attended by chairpersons of the various Research Ethics Committees across Makerere University and affiliated institutions. These included Dr. Ponsiano Ochama from the School of Medicine Research Ethics Committee (SOM-REC), Dr. Moses Ocan from the School of Biomedical Sciences Research Ethics Committee (SBS-REC), Dr. Paul Kutyabami from the School of Health Sciences Research Ethics Committee, Dr. David Kyaddondo from the Uganda Cancer Institute Research Ethics Committee, Dr. Stella Neema from the School of Social Sciences Research Ethics Committee (MAKSS-REC), Dr. Joseph Kagayi from the School of Public Health Research Ethics Committee, Dr. Joseph Kateete from the Infectious Diseases Institute Research Ethics Committee, Dr. Fred Okuku from the Uganda Heart Institute Research Ethics Committee, Dr. Kassim Sadik from the College of Agricultural and Environmental Sciences Research Ethics Committee, and Dr. Eddy Walakira from the College of Business and Management Sciences Research Ethics Committee.

The discussions reflected Makerere University’s broader ambition to consolidate its position as a leading research-intensive institution while ensuring that ethical standards, accountability, and innovation protection remain central to its academic mission.

Mak Editor

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Sylas Ruhweza: A Brief Life Marked by Meaningful Accomplishments

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The late Sylas Ruhweza, 3rd President of the Scholars Association Makerere University (SAMAK). Kampala Uganda, East Africa.

On May 29, 2026, the Mastercard Foundation Scholars Community learned of the passing of Sylas Ruhweza Atwooki, a remarkable Scholar of the Mastercard Foundation Scholars Program at Makerere University. At just 32 years old, Sylas had already made an indelible mark. He served as the representative of Makerere University on the Mastercard Foundation Advisory Board, contributing to vital decisions that shape the future. Additionally, he held the prestigious role of Minister of Information for Tooro Kingdom, an extraordinary achievement that set a powerful example for his peers and illuminated the potential for leadership and impact within the community.

Sylas was born on 19 July 1994 to the late Tinkasimire Paul Adyeeri and Ms. Ategeka Margret Abwooli in what is now Bunyangabu District. As the ninth of eleven children, he recognised early the power of education and the doors it can open. His academic journey commenced at Kaboyo Primary School, followed by Fort Portal Secondary School for his O-levels. With the backing of the Mastercard Foundation Scholarship, he confidently pursued his A-levels at Hannah International School and later enrolled at Makerere University, where he successfully earned a Bachelor of Science in Petroleum Geoscience and Production in 2022, once again bolstered by the Mastercard Foundation Scholars Program.

Sylas actively contributed to the Scholars community as the 3rd President of the Scholars Association Makerere University (SAMAK) and as the first Team Lead of the AlumNet Foundation, established in 2018, an umbrella organisation that unites all the alumni of the Mastercard Foundation at Makerere University. This organisation serves as a community of practice for Makerere University alumni, promoting agency and voice, peer mentorship, and community-impact initiatives. He demonstrated transformative leadership as Chairperson of the Mastercard Foundation Alumni Network at BRAC from 2020 to 2022. At the time of his death, Sylas served as the Minister of Information in the Tooro Kingdom and as the Strategy and Engagement Lead for the Mastercard Foundation Alumni Network’s Uganda Chapter, where he continued to advocate for collaboration and social responsibility. He was a Programme Associate at Africa Climate Collaborative, one of the Mastercard Foundation Initiatives at Makerere University, and was also pursuing his Master’s degree at Victoria University. May his soul find eternal peace.

Bernard Buteera is the Principal Communications and Public Relations Officer of the Mastercard Foundation Scholars Programme at Makerere University.

Bernard Buteera

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Makerere University Chancellor Dr. Crispus Kiyonga Appointed 2nd Deputy Prime Minister

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The Chancellor, Hon. Dr. Crispus Kiyonga gestures during an interview on 17th January 2025. 75th Graduation Ceremony, Day 5, CAES, CEDAT and CHUSS. 17th January 2025, Freedom Square, Makerere University, Kampala Uganda, East Africa.

President Yoweri Kaguta Museveni has appointed Makerere University Chancellor Dr. Crispus Walter Kiyonga as Uganda’s Second Deputy Prime Minister and Deputy Leader of Government Business in Parliament.

The appointment was announced on May 26, 2026, as part of the cabinet reshuffle for the 2026–2031 government term. Dr. Kiyonga now assumes one of the senior leadership positions in government while continuing to serve as Chancellor of Makerere University.

Dr. Kiyonga is both Chancellor and alumnus of Makerere University. He studied at Makerere University School of Medicine from 1973 to 1978, graduating with a Bachelor of Medicine and Bachelor of Surgery (MBChB). He later obtained a Master of Health Science in Population Dynamics from the Johns Hopkins School of Public Health in 2004.

Born on September 19, 1952, in Kasese District, Dr. Kiyonga attended Bwera Primary School, Nyakasura School, and Kings College Budo before joining Makerere University.

He was appointed Chancellor of Makerere University in August 2024 and formally installed in October 2024, succeeding Professor Ezra Suruma.

Incoming Chancellor Dr. Crispus Kiyonga lifting the Chancellor’s Mace.

Political and Public Service Career

Dr. Kiyonga entered national politics during Uganda’s 1980 elections, where he won a parliamentary seat on the Uganda Patriotic Movement (UPM) ticket. He later joined the National Resistance Movement during the liberation struggle and subsequently served in several senior government positions after 1986.

He represented Bukonjo County West in Parliament from 1980 to 2016 and was also a member of the Constituent Assembly that drafted the 1995 Constitution.

Over the years, Dr. Kiyonga has held several ministerial portfolios, including:

  • Minister for Cooperatives and Marketing
  • Minister of Finance
  • Minister of Internal Affairs
  • Minister of Health
  • Minister without Portfolio
  • Minister of Defence

During his tenure as Minister of Health, he played a key role in Uganda’s response to the Ebola outbreak in Gulu in 2000.

From 2016, he served as Uganda’s Ambassador to China, where he represented Uganda during a significant period of Uganda-China relations.

Dr. Kiyonga’s appointment marks a return to frontline government leadership after several years in diplomatic service and university leadership.

Significance for Makerere

As Chancellor, Dr. Kiyonga serves as the titular head of Makerere University and presides over major ceremonial functions, including graduation ceremonies.

University Chancellor Dr. Crispus Kiyonga confers a Doctorate Degree upon one of the graduands during the 76th Graduation Ceremony. 76th Graduation Ceremony, Day 2, School of Public Health (MakSPH). Commencement Speaker-Dr. Margaret J. Kigozi, Makerere University Endowment Fund Chairperson. 25th February 2026, Freedom Square, Kampala Uganda, East Africa.
University Chancellor Dr. Crispus Kiyonga confers a Doctorate Degree upon one of the graduands during the 76th Graduation Ceremony.

His appointment reflects the longstanding contribution of Makerere University alumni to public service and national leadership in Uganda and across the region.

Speaking during his installation as Chancellor in 2024, the First Lady and Minister of Education and Sports, Hon. Janet K. Museveni, noted that Dr. Kiyonga’s experience and networks would support the advancement of the university.

Makerere University congratulates Chancellor Dr. Crispus Walter Kiyonga upon his appointment and wishes him success in his new role.

The Writer is a Volunteer in the Public Relations Office, Makerere University and the Mak Sharks PRO | Est. 2014

Philemon Akoragye.
Philemon Akoragye

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