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Ugandan sickle cell researchers keep pace with aging patients

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Article courtesy Fogarty International Center

September/October 2024 | Volume 23 Number 5

Until recently in Uganda, most children with sickle cell disease (SCD) never celebrated their fifth birthday—only 30% lived past this milestone. This low survival rate was mainly due to inadequate health care interventions for these children, plus lack of widespread newborn screening, explains Dr. Sarah Kiguli , a professor at Makerere University College of Health Sciences. Things are different today. Over the past decade, the East African nation has instituted a policy of screening newborns while strengthening strategies to manage their health. This means more children with SCD are growing into adolescence and adulthood.

Challenges still exist, says Kiguli. For example, the community and district facilities where many Ugandan children are born cannot provide comprehensive services, including newborn screening. Another issue: the risk of SCD complications related to kidneys, lungs, heart—almost all organs—grows higher as patients grow older, yet scientific research in Uganda hasn’t caught up with the reality of these longer lives. As a result, teens and adults with SCD don’t get “the care they deserve,” says Kiguli.

“It’s very painful for us pediatricians to see our patients encounter challenges and problems when they transition to adult care.”

Renewed research focus

Despite years devoted to children’s health, Kiguli believes it’s time to prioritize studies exploring appropriate SCD management in teens and adults. “We need solutions that address all the patients’ needs, including reproductive health, as they transition out of childhood.” She’s spearheaded a multidisciplinary research training program for researchers focused on the needs of people with SCD at all ages: Enhancing Research capacity for Sickle Cell Disease and related NCDs across the Lifespan in Uganda (ENRICH).

“Among our PhDs, we don’t have anyone from pediatrics—and that’s fine,” says Kiguli. Importantly, the researchers are trained as a group to amplify the benefits of multidisciplinary collaboration. “We’ve been working in silos—pediatricians alone, physicians alone, social scientists alone—that won’t help us address the comprehensive needs of these patients.”

Methodology has also been given sufficient consideration. “We provide both individual and team mentorship from the beginning,” said Kiguli. Monthly meetings help trainees develop personal development goals and career path plans in the hope they will continue in the field. The program also provides research training to health professionals, such as medical doctors, laboratory personnel, and nurses, who are not necessarily doing degree programs, “so those who manage patients routinely might also benefit,” said Kiguli.

South-to-South unity

For the project, Makerere University has partnered with Busitema University, located in eastern Uganda, where “prevalence of the sickle cell trait is as high as 20%,” says Kiguli. (Sickle cell trait refers to when a person has inherited one mutated allele of the sickle cell gene, not two.) This local prevalence contrasts with about 13% prevalence elsewhere in the country. Studying the disease in a high burden locale is highly relevant, because results may influence policy and treatment guidelines.

Kiguli has other reasons for collaborating with Busitema University, which is less than 15 years old. “We want to build capacity at this young institution since our colleagues there have less chance of doing research than we at Makerere do.” Working and supervising trainees together will give Busitema’s faculty much-needed experience, while providing opportunities for faculty at both universities to learn from each other. Kiguli also hopes the new collaboration will advance progress made as result of the universities’ past partnerships. “Capacity must be built in a sustainable way,” says Kiguli.

“It’s important to work collaboratively and not competitively—this is just as important for Makerere University as it is for Busitema University.”

ENRICH trainees talk about their projects

Dr. Jackline Akello
Photo courtesy of Jackline Akello

Dr. Jackline Akello, PhD candidate

Dr. Jackline Akello, PhD candidate

My project is “Sickle cell disease in pregnancy: Experiences in provision and access to care and adverse pregnancy outcomes at Mbale and Kawempe Referral Hospitals.” As an obstetrician and gynecologist, I work as a lecturer at Makerere University and provide clinical care at the two national referral hospitals. I have encountered significant challenges in managing pregnant women with sickle cell disease (SCD) due to a number of healthcare navigation challenges. Additionally, the diverse cultural beliefs associated with SCD in Uganda affect access to care and ultimately outcome and quality of life for the patient.

By October, I will have started the enrolment of 161 pregnant women with confirmed SCD for my project. These participants will be followed throughout their pregnancies to track maternal and fetal complications, including stillbirths and low birth weight. Their experiences with the healthcare system will also be explored. As a Safe Motherhood champion, I have been focusing on hypertensive disorders in pregnancy, including pre-eclampsia, but this October at the Safe Motherhood Conference I will discuss the effects of SCD during pregnancy with the Ministry of Health. One of the endpoints of my study is to improve care for pregnant women who have SCD to enhance their pregnancy experience and outcomes.

Dr. George Paasi
Photo courtesy of George Paasi

Dr. George Paasi, PhD candidate

Dr. George Paasi, PhD candidate

My project is “The Clinical Epidemiology, Spatiotemporal Patterns and Disease Modifiers of Severe Malaria among Children with Sickle Cell Disease in Eastern Uganda.” Uganda ranks fourth among countries with high burden of SCD and is in the top 10 with respect to malaria burden. Eastern Uganda has the highest burden of both diseases. My project addresses this dual burden of SCD and malaria in eastern Uganda—I want to decipher the SCD-malaria syndemic in this region.

I’m a medical doctor, I have a master’s in public health, and I just finished a fellowship in infectious disease, epidemiology, and biostatistics. I’ve worked at Mbale Clinical Research Institute for the last 10 years. Previously, I worked on an NIH-funded trial in Africa called Realizing Effectiveness Across Continents with Hydroxyurea (REACH) as a medical officer, and now I’m embarking on this PhD training. My hope is that the findings from my study will improve the identification of patients with SCD at risk of adverse outcomes when they get malaria. I also want to identify, through spatial temporal analysis, hotspot locations that require priority interventions. I also want to gain skills as an independent researcher in SCD and make a meaningful contribution to this field.

Dr. Anita Arinda
Photo courtesy of Anita Arinda Dr. Anita Arinda, PhD candidate

Dr. Anita Arinda, PhD candidate

My project is “Prevalence, associated factors, course and impact of major depressive disorder in adolescents with SCD in Mulago National Referral Hospital.” We have limited data on mental health of adolescents with SCD, so that’s why my project mainly looks at depression in adolescents (ages 10 to 17).

In our setting, we are fortunate that children with SCD live past their fifth birthday thanks to improved health care, but this presents new challenges. During adolescence, patients enter a crucial stage where they’re trying to develop their identity, yet they’re also beginning to understand the implications of their condition—that having this serious health condition cuts their life short. I want to understand their experiences. How does depression in adolescents with SCD differ from depression in adolescents without SCD? We know that sickle cell disease causes inflammation, so does that contribute to their depression? How does depression affect clinical outcomes, if at all?

If we can understand the underlying mechanisms of depression in teens with SCD, then we might find new ways to manage their care (as opposed to conventional treatment with antidepressants). I’ll do my research at Mulago National Referral Hospital, which has a clinic dedicated to children and teens with sickle cell disease. The clinic provides many services, but unfortunately no specialized mental health services. One day I hope that changes, so that children with SCD and depression can get help early.

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2nd AI in Health Africa Conference, Not about Tech but the Vulnerable

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Hon. Dr. Monica Musenero (3rd Right) flanked by Left to Right: Mr. Ambrose Ruyooka, Dr. Rose Nakasi, Dr. Stella Kivila, Prof. Buyinza Mukadasi and Dr. Andrew Kambugu at the Conference Opening Ceremony on 6th November 2025. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.

The two-day 2nd Artificial Intelligence (AI) in Health Africa Conference that kicked off today in the Main Hall, Makerere University has been described as not being about technology but about people – the vulnerable communities bearing the burden of infectious diseases and other health challenges – and the promise AI holds as a panacea. Officially opened by Hon. Dr. Monica Musenero, Minister of Science, Technology and Innovation the conference will be held under the theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”.

Africa Must Enter the ‘Evil Forest’

In her now characteristic style of speaking from the heart, Hon. Dr. Musenero observed that Africa has from the first industrial revolution to the current fourth and impending fifth industrial revolutions experienced emotions ranging from non-recognition, rejection and skepticism to the current consumption with awe. This current emotion, though receptive unlike previous ones, continues to position Africa at a disadvantage economically, she noted.

Hon. Dr. Monica Musenero delivers her keynote address. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero delivers her keynote address.

“We are positioning ourselves to disadvantage in skill; we have positioned ourselves at the consumption end and we’ve stood in awe of this technology,” she observed, using the example of the amount of admiration a user who whips out the latest iPhone 17 attracts from those around them. “We respect you for your iPhone 17, but I would be happier if you were able to design and manufacture iPhone 5” intimated Hon. Dr. Musenero.

The Minister urged fellow scientists to wake up to the realization that the future of Africa lies in their hands. “We can no longer be passive participants, we can no longer reside on the shallow end of science; we must be willing, as I said when I was here last week, to enter the ‘evil forest’”.

Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Hon. Dr. Monica Musenero (Centre) with exhibitors after the official opening ceremony.

The ‘evil forest’ is Hon. Dr. Musenero’s analogy of Africa’s perception of current technology ecosystem drawing parallels with scenes often dramatized by Nigerian Movies. She notes that though depicted in these movies as scary and potentially dangerous, the ‘evil forest’ is loaded with hidden treasures, necessitating resilience and wisdom for one to navigate the pitfalls until they discover the treasure trove. Upon discovery, the value of this treasure has the potential to turn around the fortunes of the family, community or entire kingdom. Entering the ‘evil forest’ therefore, is her way of encouraging scientists to go beyond adapting imported technology for local use to understanding how it works enough to develop homegrown solutions.

Building AI Capacity through Synergy

Representing the Vice Chancellor, Prof. Barnabas Nawangwe, the Academic Registrar, Prof. Buyinza Mukadasi concurred with Hon. Dr. Musenero that Uganda needs to accelerate investment capacity in AI, if it is to be used as tool to manage health challenges. He nevertheless underlined the steps Makerere has undertaken to close the gaps by hosting units such as the Infectious Diseases Institute (IDI), AI and Health Lab, Innovation Pod, while working with various partners.

Prof. Buyinza Mukadasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi.

“We want to renew our commitment that we shall continue to translate our research findings into service delivery and products that improve the livelihoods of our people,” pledged Prof. Buyinza, who also noted that this will be undertaken within institutional ethical guidelines and policies, bolstered by good practices and recommendations arising from the conference.

Taking cognizance of contributions of various partners to strides made so far, the Permanent Secretary Ministry of ICT and National Guidance, Dr. Aminah Zawedde who was represented by Mr. Ambrose Ruyooka, the Ministry’s Head of Department of Research and Development, thanked the Makerere University AI Health Lab, IDI, Health AI for All Network, the Research and Innovation Fund, the African Population and Health Research Centre, and the Mastercard Foundation for convening the second edition of the conference.

“This year’s theme aligns perfectly with Uganda’s digital transformation vision. It reminds us that while innovation is powerful, true progress lies in ensuring it is equitable, ethical, locally relevant, and accessible to all” read Dr. Zawedde’s remarks.

Mr. Ambrose Ruyooka. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Mr. Ambrose Ruyooka.

She noted that when used responsibly, AI empowers healthcare workers to do more with greater precision and efficiency while extending services to under-served communities, essentially amplifying their impact whilst preserving the essential human touch that defines care. Dr. Zawedde reiterated the Government of Uganda’s commitment to positioning AI as a catalyst for national development and improved service delivery through the national AI governance framework. “By the end of 2025, we expect to reach a decision on whether to adopt a comprehensive AI policy or a flexible, sector-led regulatory approach.”

Referring to projects already underway at the College of Computing and Information Sciences (CoCIS), the Principal, Prof. Tonny Oyana underscored the great promise AI holds for not only improving affordability but also diagnosis of disease. He nevertheless called for targeted investment in data centres so as to build the required capacity to process the large amount of data that AI thrives on.

Prof. Tonny Oyana. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Tonny Oyana.

The Executive Director IDI and conference Co-Chair, Dr. Andrew Kambugu described the conference timing as “impeccable”. Citing a recently convened conference on Communicable and Non-Communicable Diseases that discussed Universal Health Coverage, he shared “there are people in this country who are one step away from disaster because of health.”

He therefore paid tribute to his conference Co-Chair, Dr. Rose Nakasi, whose AI-automation work with the light microscope, one of game-changing inventions in human medicine to-date, has improved precision, accuracy and efficiency in diagnosis of malaria, tuberculosis and cancer in healthcare facilities. Dr. Kambugu therefore urged his audience to always be eager to learn about the capabilities game changing tools such as AlphaFold.

Dr. Andrew Kambugu. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Andrew Kambugu.

“Our African Centre of Excellence in Bioinformatics & Data Intensive Science (ACE) in collaboration with CoCIS has been one of the first trainers of AlphaFold in Africa” remarked Dr. Kambugu. He added that the to ensure inclusive training ACE has attracted funding to support the She Data Science (SHEDS) project, an initiative that offers MSc and PhD fellowships to Ugandan women in the fields of data science and bioinformatics, with a strong emphasis on health data.

Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left). 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Prof. Buyinza Mukadasi (Right) receives a SHEDS gift pack from Dr. Andrew Kambugu (Left).

How Ocular is shaping healthcare

Conference Co-Chair and Principal Investigator of Ocular, Dr. Rose Nakasi noted that their project that aims at empowering healthcare professionals with AI-powered microscopy was motivated by the fact that wrong diagnoses have a cascading effect on prescription, treatment, recommendation and surveillance services. “Where health practitioners have been taking 30 minutes or more to diagnose malaria, and days to diagnose cancers, we are slashing down that time to literally 5 seconds to diagnose and make a recommendation.” She added.

Dr. Nakasi added that beyond diagnosis, the Ocular project is supporting the Ministry of Health with more precise surveillance and monitoring of diseases by quicker augmentation of information for faster roll-out of interventions as opposed to current weekly or monthly reporting period required by the Digital Health Information System (DHIS 2).

Dr. Rose Nakasi. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
Dr. Rose Nakasi.

“The beauty about AI is that it has the capability not to just learn with one dataset but also provide insights on different pieces of data – for diseases such as malaria where climate has an effect, we want to integrate climate datasets and seasonality aspects so that interventions by Government are timely and targeted to specific locations.”

The Ocular project exhibition setup. 2nd Artificial Intelligence (AI) in Health Africa Conference under theme “Setting AI for Sustainable and Inclusive Health Systems in Africa”, Opening Ceremony 6th November 2025, Main Hall, Makerere University, Kampala Uganda, East Africa.
The Ocular project exhibition setup.

Beyond the plenary sessions, the 2nd AI in Health Africa Conference will feature abstract presentations, a Makerere AI Health Lab Showcase, Breakout Sessions, Workshops, Masterclasses and a hackathon for prototypes developed during the conference. Please see downloads for a detailed concept and programme.

Mark Wamai

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JASH2025 opens with call for renewed commitment to prevention, innovation and partnership

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Dignitaries pose for a group photo at the JASH2025 opening ceremony on 5th November 2025. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.

The 19th edition of the Joint Annual Scientific Health Conference (JASH) jointly held with the Inaugural National Communicable and Non-Communicable Diseases Conference (NACNDC) was officially opened by Hon. Jane Ruth Aceng Ocero, Minister for Health on 5th November 2025. The Minister called for renewed commitment to prevention, innovation, and partnership if Uganda is to end preventable communicable and non-communicable diseases by 2030.

The Conference themed, ‘Unified Action Against Communicable and Non-Communicable Diseases’ held at Speke Resort Munyonyo, Kampala, Uganda from 3rd to 7th November 2025 is organised by Makerere University College of Health Sciences (MakCHS), Makerere University School of Public Health (MakSPH) and Ministry of Health (MoH). The convening brings together over 500 delegates from government, academia, civil society, development partners, and the private sector. 

Hon. Dr. Jane Ruth Aceng Ocero Minister of Health who was the Chief Guest, officially opened the conference. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Hon. Dr. Jane Ruth Aceng Ocero Minister of Health who was the Chief Guest, officially opened the conference.

Highlighting the areas where commendable progress has been made including: full childhood vaccination from 37% in 2000 to 68% in 2022, reduced child stunting from 45% to 26%, increased life expectancy from 45 years in 1986 to 68 years in 2022, strong HIV control among others. The Minister also noted that Uganda continues to grapple with challenges like sub-optimal uptake of new vaccination anti-gens fueled by misinformation, myths and rumors; geographical disparities in access to quality health services; 29.1% of Ugandans being obese or overweight signaling the risk to develop NCDs like hypertension and diabetes.

‘To address the challenges, we must: strengthen our health systems, ensuring that services are accessible, equitable, and of high quality; enhance our community engagement and empowerment, enabling individuals to make informed health decisions, providing informationm Foster partnerships across sectors and actors to create a supportive environment for elimination of communicable and non-communicable diseases’, the Minister said.

She further said, ‘unified action against communicable and non-communicable as theme of this conference calls for integrated, people-centred approaches to prevention and care’. She emphasized that disease control is not the responsibility of the health sector alone, it requires collaboration with education, local government, water and sanitation, transport, and private sectors.

PS-MoH Dr. Diana Atwine. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
PS-MoH Dr. Diana Atwine.

In her remarks to the congregation, Dr. Diana Atwine, Permanent Secretary-MoH commended the organisers for successfully organizing the conference. She noted that the inaugural NACNDC marks a milestone for the health sector in addressing the rising double disease burden of communicable and non-communicable among the Ugandan population.

‘The theme aligns with our new strategic direction that emphasises collaboration amid declining external funding, therefore, let us continue to plan, invest, and be accountable together’, Dr. Atwine said.

She noted the multiple achievements and remaining challenges of the health sector underscoring the priorities of MoH including: upgrading key hospitals, expanding blood banks, recruitment of specialised staff, equipping regional facilities, scaling-up digitization, and strengthening immunization and community health systems.

The Permanent Secretary expressed her gratitude for the work of the organizing committee, partners and participants for making the conference a success. She called for sustained momentum of collaboration and innovation reiterating commitment of the MoH in supporting the platform created from this conference.

She re-echoed the role of academia in the unified action, ‘Academia we depend on you for innovative ways. Your research should answer our burning questions to solve our problems’.

Prof. Bruce Kirenga, Principal MakCHS. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Bruce Kirenga, Principal MakCHS.

Prof. Bruce Kirenga, Principal-MakCHS appealed to government to consume products from training institutions especially nurses and other allied health professionals noting that currently 40,000 nurses are not employed, many turning to odd jobs. He thanked government for the gains in science and enabling the partnerships leading to such meetings and dialogue on solutions to national challenges.

Prof. Kirenga reminded participants that MakCHS is celebrating 100 years with an upcoming Alumni Dinner to be held on 12th December 2025, he invited all well-wishers to attend calling for their support as we fundraise to refurbish infrastructure at the college and build new facilities amidst the increased number of learners.

Prof. Rhoda Wanyenze, Dean MakSPH. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Rhoda Wanyenze, Dean MakSPH.

Professor Rhoda Wanyenze, Dean MakSPH expressed commitment of the university and researchers to continue to serve in this space by providing data to inform evidence-based policy making. ‘Rather than describe existing problems we commit to offer innovative solutions to the problems and train and produce a workforce that is aligned to requirements of where they serve’ she added.

Delivering the speech of Professor Sarah Ssali, Deputy Vice Chancellor-Academic Affairs, Makerere University, Professor Robert Wamala, Director-Research & Innovations said ‘Makerere University is honored to co-host the conference with Ministry of Health. This partnership shows that research, policy and practice must move together to solve challenges of our population. Let this conference not be another meeting but a beginning for sustained health dialogue’.

Prof. Wamala Robert represented DVC/AA. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Prof. Wamala Robert represented DVC/AA.

Delivering the conference objectives at the conference, Dr. David Musoke, Associate Professor at MakSPH and Conference Co-Chair, underscored the need for integrated, evidence-driven approaches to Uganda’s evolving health challenges. 

He noted that the joint conference, co-convened by the Ministry of Health, MakSPH, and partners, marks a pivotal step in aligning research, policy, and community practice to strengthen the country’s health systems.

Dignitaries pose for a group photo with stakeholders. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, Opening Ceremony 5th November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Dignitaries pose for a group photo with stakeholders.

The conference that began on 3rd November with pre-conference sessions on Mental Health, Paediatric Healthcare, among others continues till 7th November with participants continuing to dialogue on how to build a resilient health system for Uganda within the changing funding landscape.

Zaam Ssali

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NACNDC & 19th JASH Symposium Breaks Silence on Mental Health in Schools & Universities

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Justice Duncan Gaswaga (Left) with officials including Dr. Juliet Babirye (3rd Right) and panelists who included Dr. Ane-Marthe Solheim Skar (3rd Left), Dr. Harriet Aber-Odonga (Right) and others. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.

The Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners are jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November. Ahead of the official opening on Wednesday, 5th November, a Mental Health Pre-Conference Symposium was held under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives.” The session, held at Victoria Hall, Speke Resort Munyonyo, brought together mental-health experts, policymakers, researchers and education stakeholders to explore how learning institutions can strengthen emotional well-being, resilience and support systems for young people across Uganda.

Justice Duncan Gaswaga delivers his address. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Justice Duncan Gaswaga delivers his address.

Speaking as Guest of Honour, Justice Duncan Gaswaga of the African Court on Human and Peoples’ Rights urged stakeholders to recognise the deep connection between mental health and human rights, noting that mental well-being cannot be separated from the social and economic realities in which people live. He commended the theme on “breaking the silence,” arguing that open conversations and early prevention offer the most cost-effective path to protecting communities, especially learners. Drawing from his judicial experience, he shared first-hand accounts of emotional trauma faced by judges who regularly encounter distressing evidence in court, including cases from the LRA conflict, and observed that legal professionals, like health workers and teachers, are not immune to psychological strain. Justice Gaswaga raised concern over rising mental-health challenges in schools and universities, citing data showing increased depression, substance use, and emotional distress among students, particularly girls. He attributed these trends to pressures such as long study hours, parental absence, peer influence, online risks, poverty, and untreated trauma. He called for stronger government funding, implementation of school mental-health policies, closer parental involvement, and coordinated action across sectors, adding that legal reforms, including debate on decriminalising attempted suicide, may be necessary to ensure individuals can seek help without fear of punishment.

Deputy IGG Mrs. Anne Twinomugisha Muhairwe. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Deputy IGG Mrs. Anne Twinomugisha Muhairwe.

The Deputy Inspector General of Government (IGG), Mrs. Anne Twinomugisha Muhairwe emphasised the urgent need to prioritise mental health across all sectors, noting that society often treats the subject as taboo despite its profound impact on productivity, ethics and service delivery. She argued that mental well-being is not only a personal concern but a governance issue, pointing out that health workers, who shoulder enormous responsibility, also require structured support systems to safeguard their psychological welfare. Citing recent incidents, including a case in Masaka where a patient reportedly died after a medical worker allegedly refused treatment over a payment dispute, she warned that unresolved mental-health challenges can influence behaviour and decision-making in critical service spaces. The IGG further highlighted a link between mental health and corruption, suggesting that addressing emotional strain and psychological pressures among public servants could contribute to ethical conduct and better public service outcomes. She encouraged continued engagement on the topic, calling for mental-health considerations to be integrated into anti-corruption strategies and institutional reforms, and expressed readiness to contribute more deeply to future discussions.

Dr. Racheal Nuwagaba. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Dr. Racheal Nuwagaba.

Delivering the keynote at the Mental Health Pre-Conference Symposium, Dr Racheal Nuwagaba of Makerere University urged stakeholders to confront mental health as it is today and abandon siloed approaches, calling for full integration of services into primary health care and evidence-led policy. She said nearly two decades of clinical practice and teaching have shown her that young people carry mounting pressures, highlighting Uganda’s youthful demographics and pointing to drivers such as sleep deprivation, academic strain, abuse and neglect. Citing recent trends, she warned against sensational statistics and urged clear differentiation between mild, moderate and severe symptoms, noting post-COVID rises in depression, higher burdens among refugees and significant risks for girls and senior students. Dr Nuwagaba stressed the frequent co-occurrence of mental illness with addictions and physical conditions, explaining that untreated disorders worsen over time and can impair brain function, while treatment and adherence improve outcomes. She encouraged mindfulness and presence in classrooms and clinics, and pressed institutions to use research to guide decisions, reduce stigma, and design culturally grounded, community-based responses. Concluding, she appealed for sustained collaboration across sectors and for the deliberate hiring and fair remuneration of professional mental-health providers to safeguard learners’ emotional, social and academic well-being.

Dr. Kenneth Kalani. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Dr. Kenneth Kalani.

The symposium also featured a panel discussion on Mental Health in Schools and Universities, chaired by Dr Kenneth Kalani from the Ministry of Health, and bringing together experts including Dr Harriet Abbe, Prof Ane-Marthe Solheim of the Norwegian Institute of Public Health, and Ms Rebecca Namakula from the Ministry of Education and Sports. Panelists underscored the urgency of addressing mental-health challenges among learners, with insights highlighting early substance use among children as young as six, the need for teacher training in mental-health literacy, and the critical role of schools as early-detection points. They emphasised stronger linkages between health facilities and learning institutions, investment in prevention and early intervention, and the importance of equipping teachers, parents and school leaders with the skills to identify and respond to distress. The panel agreed that mental-health support must extend across the entire school community and be backed by policy enforcement, coordinated services and sustained collaboration across sectors.

Dr. Hafsa Lukwata. Ministry of Health (MoH), Makerere University School of Public Health (MakSPH), Makerere University College of Health Science (MakCHS) and other partners jointly hosting the National Annual Communicable and Non-Communicable Diseases (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025, running from 3rd to 7th November, Pre-Conference Symposium under the theme “Breaking the Silence: Advancing Mental Health Awareness and Resilience,” with a sub-theme on “Advancing Mental Health in Schools and Universities — Research and Policy Perspectives” 3rd November 2025, Victoria Hall, Speke Resort Munyonyo, Kampala Uganda, East Africa.
Dr. Hafsa Lukwata.

In her closing remarks, Dr Hafsa Lukwata, Assistant Commissioner for Mental Health and Control of Substance Abuse at the Ministry of Health, urged Ugandans to break the silence around mental well-being and be intentional about seeking help and supporting one another. She noted that mental-health challenges are widespread across schools, homes and workplaces, and emphasised that silence only deepens the burden. Dr Lukwata encouraged institutions to appoint mental-health focal persons and called for sustained dialogue, continued collaboration and proactive efforts to build resilience in communities. She reminded participants that improving mental health begins with individual awareness and collective action, urging them to treat the day’s engagement as a starting point for strengthening support systems across the country.

Eve Nakyanzi

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