Health
NCDs Symposium 2023: Stakeholders Pledge to Work together to Address growing burden in Uganda & Beyond
Stakeholders pledged to work together to address the growing burden of Non-Communicable Diseases (NCDs) in Uganda and beyond. The pledge was made at the NCDs Symposium held on Saturday 4th March 2023 and hosted by Makerere University College of Health Sciences (MakCHS), as a member of the Alliance of Research Universities in Africa (ARUA) NCD Centre of Excellence. The theme of the symposium was ‘Advances in NCD Training, Research and Community Impact’.
Research shows that, globally, non-communicable diseases (NCDs) are responsible for a significant proportion of deaths, with 41 million people dying from these chronic diseases each year. NCDs, also known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behavioural factors. The main types of NCD are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
NCDs disproportionately affect people in low- and middle-income countries, where more than three-quarters of global NCD deaths (31.4 million) occur. In Uganda, the number of people living with NCDs has been increasing dramatically, making NCDs a major public health threat. For instance, 74,354 new cases of diabetes were seen at health facilities in Uganda in 2009-10 compared to 58,523 five years earlier showing an increase of 27% (HMIS data 2009/10). In 2013, the Uganda Diabetes Association revealed that over 200,000 children had diabetes and expressed fears the number could be higher because many of the children do not report to the hospital for diagnosis.
In her remarks as host, Professor Damalie Nakanjako, The Principal College of Health Sciences, Makerere University, in a special way welcomed participants to the Symposium and noted that the purpose of the event was to showcase the latest advances in NCD training, research, and community impact, and to provide a platform for stakeholders to engage and collaborate on issues related to NCDs.
Citing WHO data, Professor Nakanjako noted that NCDs represent the largest cause of mortality in adults with 86% of these premature deaths occurring in middle-income countries such as Uganda. She further pointed out that the incidence of NCDs among children, particularly diabetes, is increasing, indicating the urgent need for attention.
Professor Nakanjako stressed the importance of data-driven interventions, knowledge translation, and a multi-sectoral approach in addressing NCDs, and called for more investment in NCD research, collaborations, and regular exercise among children. She also reiterated Makerere University’s commitment to addressing NCDs through continuous advances in NCD training, research, and community engagement.
WHO Key Facts On Non-Communicable Diseases (NCDs)
- Non-communicable diseases (NCDs) kill 41 million people each year, equivalent to 74% of all deaths globally.
- Each year, 17 million people die from a NCD before age 70; 86% of these premature deaths occur in low- and middle-income countries.
- Of all NCD deaths, 77% are in low- and middle-income countries.
- Cardiovascular diseases account for most NCD deaths, or 17.9 million people annually, followed by cancers (9.3 million), chronic respiratory diseases (4.1 million), and diabetes (2.0 million including kidney disease deaths caused by diabetes).
- These four groups of diseases account for over 80% of all premature NCD deaths.
- Tobacco use, physical inactivity, the harmful use of alcohol and unhealthy diets all increase the risk of dying from an NCD.
- Detection, screening and treatment of NCDs, as well as palliative care, are key components of the response to NCDs.
During his speech, Dr. Fred Bukachi, the Director of ARUA Centre of Excellence for NCDs, highlighted the urgent need to address the rising prevalence of non-communicable diseases (NCDs) in the region and beyond through research, capacity building, and dissemination of findings. The Centre’s main objective is to develop scientific evidence for NCD policies, prevention, management, and control, while engaging with communities. To achieve this, Dr. Bukachi presented several strategies, including the creation of multi-disciplinary research programs, a training research and mobility program, an NCD research and data repository for Africa, and an annual international NCD symposium.
In addition, Dr. Bukachi emphasized the Centre’s commitment to improving the health and well-being of people in sub-Saharan Africa and beyond by addressing the NCD epidemic through research and capacity building. The audience responded positively to his presentation, with many impressed by the Centre’s ambitious goals and plans for tackling NCDs in Africa.
In his remarks, read by Dr. Frank Mugabe, Dr. Oyoo Charles Akiya, the Commissioner of Health Services-NCD Ministry of Health, stated that non-communicable diseases and injuries (NCDIs) are on the rise in Uganda. He revealed that the burden of NCDs has more than doubled in the last 20 years, with 22% of adults at risk of premature death (30-70 years) as of 2016. NCDs account for 41% of all deaths in the country.
Dr. Akiya cited the NCD risk factor survey and other studies, highlighting heavy alcohol consumption in men and women, consumption of unhealthy diets, tobacco use, physical inactivity, and obesity as some of the problems that need urgent attention. Data on high burden NCD conditions reveal that 24% of adults in Uganda suffer from hypertension requiring treatment, with only 24.3% accessing treatment. The prevalence of diabetes is estimated at 1.4%, and there is a high prevalence of sickle cell disease in the central, eastern, and northern parts of the country, with 1.3% of the population having the trait.
Mental health disorders, especially depression, are also prevalent, with over one million Ugandans experiencing depression.
On government efforts towards NCDS, Akiya revealed that Uganda is conducting the 2nd risk factor survey thanks to the World Health Organization and the School of Public Health.
Moving forward, Dr. Akiya proposed priority areas for research and training ; including the need to quantify the level of misinformation around diabetes treatment, implement preventive programs for known carrier communities of sickle cell disease, determine the cause and risk factors for increased cases of gastrointestinal cancer in Southwestern Uganda, understand the biomass gap and its correlation to chronic respiratory diseases, determine the gap in mental health service provision among general health workers, reduce the cost of kidney chronic disease transplant services, increase awareness of cardiovascular disease screening, and determine and document the cost of road traffic-associated injuries to the health sector and the country to halt these conditions.
In his remarks as Chief Guest, Professor Umar Kakumba, on behalf of Makerere University’s Vice Chancellor Professor Barnabas Nawangwe, commended academia for their role in addressing emerging health threats, adding that Makerere University, as a research-led institution, is committed to supporting NCD activities through training, research, and community engagement. He emphasized that beyond training and research, there is a need to go to communities and share knowledge, as there is a gap in knowledge uptake around NCDs.
Professor Kakumba also highlighted the role of the private sector in supporting these causes, as a healthy population is key to their business success. He thanked Arua partners for taking the lead in addressing NCDs, which are responsible for 71% of global deaths and 85% of premature deaths in low and middle-income countries, including Uganda.
Moving forward, Professor Kakumba proposed a collaborative effort among stakeholders to address NCDs comprehensively. He emphasized the need for a holistic approach that involves the government, private sector, civil society organizations, and academia to address the growing burden of NCDs in Uganda.
He reiterated the commitment of Makerere University in supporting NCD activities through research, training, and community engagement, and he called on other institutions to join in this effort to achieve a healthier population and a more prosperous country.
In her remarks, Dr. Kasule Hasifa discussed the priority areas for research and training in non-communicable diseases (NCDs) identified by the World Health Organization (WHO), including the need to prevent and control NCDs through public health interventions and policies, address the social determinants of NCDs such as poverty and education, improve healthcare accessibility and quality particularly in low- and middle-income countries, strengthen health systems to better respond to the growing burden of NCDs, and promote research on the causes, prevention, and treatment of NCDs.
The event featured presentations from several NCD groups at MakCHS, including Cardiovascular Diseases, Renal Diseases, Diabetes Mellitus & Other Endocrine Disorders, Cancers, Mental Health Disorders, Respiratory Diseases and Lung Health, Sickle Cell Disease, and Other Haematological Conditions, as well as Interactions between NCDS and Infectious Diseases.
The symposium was attended by researchers, students, academicians, policymakers, practitioners, and health advocates with a special interest in NCDs. The day was crowned off with cake-cutting and all participants pledging to work together in addressing NCDs.
At the symposium, stakeholders agreed that it is crucial to work collaboratively to comprehensively address the growing burden of NCDs in Uganda. They recognized the need to implement preventive programs, increase awareness of cardiovascular disease screening, improve healthcare accessibility and quality, particularly in low- and middle-income countries, and promote research on the causes, prevention, and treatment of NCDs. It was emphasized that a holistic approach involving the government, private sector, civil society organizations, and academia is necessary to achieve a healthier population and a more prosperous country.
Agriculture & Environment
Makerere Hosts Inaugural Falling Walls Lab Competition as Innovators Pitch Solutions to National Challenges
Students and researchers from Makerere University and other institutions pitched 12 innovations addressing challenges in healthcare, clean energy, agriculture, waste management and community resilience during the inaugural Falling Walls Lab Kampala, held at the School of Public Health Auditorium, Makerere University.
The competition brought together emerging innovators to present solutions to practical challenges through a three minute pitch, followed by questions from a panel of judges.
Modelled on the Falling Walls format that originated in Berlin, the event required each participant to identify a “wall” a problem or barrier, and demonstrate how their innovation seeks to break it down.
Mudhasi wins with newborn jaundice screening device
Andrew Mudhasi of Makerere University emerged as the overall winner with a score of 90 per cent for a low cost medical device designed to improve newborn jaundice screening across different skin tones.
Mudhasi explained that the device uses optical sensor technology and a skin tone targeting algorithm to provide a rapid reading, with the aim of helping nurses and clinicians identify jaundice more efficiently.
During questions from the jury, Mudhasi said the device had not yet been tested on actual babies but had undergone laboratory testing using simulated skin tones.
He reported an accuracy rate of 94 per cent when the device was compared with laboratory spectrophotometers.
The innovation is intended initially for use in clinics and hospitals, with Mudhasi saying the team is also considering a version that could eventually allow mothers to screen babies at home.
Mudhasi’s innovation has previously received recognition at the African Business Concept Challenge and the iF Design Student Award, according to his presentation.
Rhonda’s innovation tackles diaper waste
Rhoda John of the University of Nairobi emerged in second place with 89.6 per cent for an innovation addressing the problem of used diaper waste.
Under the theme “Breaking the wall of diaper waste and drug soils,” Rhonda explained that her team extracts sodium polyacrylate, the absorbent polymer found in diapers, and replaces the sodium with potassium.
The resulting potassium based superabsorbent material is designed to act as a “water battery” in soil by absorbing and retaining water for plants during dry periods.
John said testing showed a 99 per cent increase in germination and a 23 per cent increase in drought resistance.
The innovation also seeks to reduce the amount of used diapers ending up in landfills and the environmental effects associated with their decomposition.
During the question and answer session, John explained that her team was working with government environmental officials in Nairobi on a pilot collection system to address the challenge of gathering used diapers at scale.
Mahera takes third place with herbal peptic ulcer treatment
Stuart Mahera of Makerere University finished third with 86.2 per cent for a herbal formulation targeting peptic ulcers.
Presenting under the theme “Breaking the wall of Nature and Modern Medicine,” Mahera argued that conventional treatment for peptic ulcers can involve multiple medicines and may be associated with side effects and antimicrobial resistance.
His proposed formulation, MARAC capsules, is intended as a monotherapy, combining properties required for peptic-ulcer treatment in a single capsule.
Mahera said his team had carried out quality control work, including characterisation and dose quantification, and had conducted preclinical trials on laboratory mice.
He also told the jury that an application had been submitted to the National Drug Authority as the team awaits the next stage of the regulatory process.
According to Mahera, the proposed seven day treatment would cost about Shs21,000, compared with the existing 14 day treatment approach.
Innovators present solutions to practical challenges
The remaining presentations covered a wide range of challenges.
Esther Nakungu of Utamu University presented Agri-Track, a digital record keeping solution intended to improve visibility, accountability and management of farm operations and financial information.
Dr. Jimmy Chachiga, a Makerere University participant, presented a solar photovoltaic cooker with a heat storage system designed to provide a cleaner and more reliable cooking option during both sunny and non sunny periods.
His presentation focused on reducing dependence on biomass fuels and addressing the challenges associated with intermittent solar energy.
Abdul Noor Luttamaguzi, a PhD student and senior government fisheries officer, presented a mobile application aimed at helping fish farmers and extension officers report, track and manage disease outbreaks.
Henry Duke Tamale presented a herbal cream targeting antibiotic resistant biofilm infections associated with diabetic foot ulcers.
Marvin Seruwu proposed adapting existing near infrared brain monitoring technology to help detect extra-axial brain bleeds in health facilities where access to CT and MRI equipment is limited.
His proposal seeks to repurpose existing technology towards a diagnostic need that could be particularly important in settings where advanced imaging facilities are not readily available.
Kennedy Kisame presented a poultry alert and diagnosis system combining satellite weather information with computer vision disease detection. The proposed system could be accessed through a smartphone application, SMS or USSD, making it potentially usable by farmers with limited internet access.
Frank Atwiine proposed a solar powered mobile diagnostic van designed to bring ultrasound and other diagnostic services closer to rural communities.
Johnson Makmot, a software and blockchain developer, presented a platform that combines GPS tracking and blockchain-based tokens to incentivise and verify plastic-waste collection in Kampala.
Dr. Nelson Ndugu, from a partner university, presented an artificial intelligence tool designed to translate agricultural research publications into local Ugandan languages and generate voice notes for radio-based extension delivery.
The final presentation came from Dr. Juliet Akola, a Ugandan post doctoral researcher at Mangosuthu University of Technology in South Africa.
Akola presented a community digital resilience initiative focused on mapping risks in Kampala’s informal settlements, including flooding, fire, poor sanitation, waste management and inadequate infrastructure.
Her proposal seeks to combine local community knowledge with geographical information systems and link identified risks to action plans involving municipalities and other stakeholders.
Nawangwe calls for more investment in innovation
Closing the event, Prof. Nawangwe congratulated all the participants and described their presentations as an important beginning for Makerere University, Uganda and the wider region.
Drawing on his experience attending the Falling Walls conference in Berlin, the Vice Chancellor said initiatives of this nature are important because innovation will play a major role in determining the future of countries.
He encouraged participants to make their pitches more precise by clearly identifying the problem they are addressing, explaining their proposed solution and demonstrating what they have already achieved.
Prof. Nawangwe also welcomed the participation of innovators from other universities and countries, noting that the Kampala event had attracted participants beyond Makerere.
He thanked the Africa Office of the Falling Walls Foundation for its role in bringing the initiative to Makerere and encouraged continued support for innovation.
The Vice Chancellor further linked innovation to Uganda’s growing youth population and the need to develop home-grown solutions to address challenges such as youth unemployment.
The inaugural Falling Walls Lab Kampala ultimately provided a platform for innovators to move ideas beyond the classroom and laboratory and demonstrate how research, technology and creativity can be applied to challenges affecting communities.
| Position | Winner | Institution | Score |
| 1st | Andrew Mudhasi | Makerere University | 90% |
| 2nd | Rhoda John | University of Nairobi | 89.6% |
| 3rd | Stuart Mahera | Makerere University | 86.2% |
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