Makerere University Research and Innovations Fund: Request for Applications (RFA) Supported by the Government of the Republic of Uganda
Round 4, Track 1: New Research & Innovation Agenda-based Proposals Financial Year 2022/2023
SECTION A: BACKGROUND
A1. Funding opportunity description
Makerere University received special funding from the Government of the Republic of Uganda, to support high impact Research and Innovations. The Financial Year 2022/23 will be the fourth year of this fund’s availability. The fund illustrates the increasing importance that the Government attaches to Research and Innovation as a driver of socio-economic transformation. The objective of the fund is to increase the local generation of translatable research and scalable innovations that address key gaps required to drive Uganda’s development agenda. The fund is therefore aimed at complementing available funding to address unfunded priorities critical to accelerating development. Over the last three Financial Years (2019/2020, 2020/21 and 2021/2022), government appropriated 79 Billion Uganda Shillings. Between the three years, MakRIF has funded a total of 775 projects across all sectors critical for development, of which 204 have been completed. In the next Financial Year (2022/23), Makerere University expects to receive about 30 Billion Uganda shillings (about US$ 8,100,000) under the Government Research and Innovation Fund (RIF). Of this, at least 6 Billion Shillings will fund new ideas that respond to a widely consultative Research Agenda focused on national priorities while the rest will fund continuing projects from previous financial years, extension of multi-year projects, needs based priorities, and commercialization/scaling of prior funded projects. The Makerere University Research and Innovation Grants Management Committee (GMC) therefore announces the RIF Round 4, Track 1 (New Research & Innovation Agenda-Based Grants). Available funds are obligated for the Financial Year 2022/2023. The GMC therefore invites applications with original ideas that demonstrate a clear link to key thematic areas of the National Research and Innovation Agenda.
A2. Research for Economic Development
To transition to middle-income status, low-income countries must increasingly invest in research and innovations that provide solutions to persistent development challenges. Universities should be at the fore-front of driving this research agenda. The Government of Uganda is currently implementing the 3rd National Development Plan (NDP) (2020/21 – 2024/25). However, the NDP and sector specific plans require research to fill evidence gaps. The main objective of the RIF is to support R&I initiatives that contribute to better delivery of National Development initiatives in all sectors critical to the economy.
A3. Scope and Technical Description of the Research and Innovation Grant
The RIF GMC’s terms of reference include development of an instructive research agenda as the basis for identifying funding priorities. The GMC conducted a comprehensive stakeholder consultation to identify priority thematic areas of interest for national development. These consultations included meetings with representatives from key government sectors, semi-autonomous government agencies, the private-for-profit sector and civil society. The GMC triangulated this information with that from the National Development Plan III, the Makerere University Strategic Plan and Research Agenda and the critical areas spelled out in the National Budget for FY2022/2023. The RIF Round 4, Track 1 (Research & Innovation Agenda-Based Grants) will therefore specifically target research and innovation projects that align with priority thematic issues in the instructive Research Agenda that arose from these consultations. Research and Innovation ideas are therefore sought in the following thematic areas:
Theme 1: Transforming the agricultural sector to drive development Theme 2: Achieving Sustainable health as a means to sustainable development Theme 3: Re-imagining Education to unlock capacity for economic development Theme 4: Water, sanitation and the environment: A pre-requisite to sustainable development Theme 5: Harnessing the social sector, culture and arts to drive development Theme 6: Harnessing tourism, wildlife and heritage to drive development Theme 7: Sustainable Planning, finance and monitoring as catalysts for growth Theme 8: Leveraging public service and local administration for efficient service delivery Theme 9: Defense and security: Achieving sustainable peace and stability Theme 10: Strengthening law, governance, human rights and international cooperation as pre-requisites for development Theme 11: Harnessing Information and Communication Technology to drive development Theme 12: Works, manufacturing, science and technology as tools to accelerate development Theme 13: Solutions to catalyze business and enterprise Theme 14: Energy and Minerals as drivers of rapid economic development
The Government Research & Innovation (R&I) Grants will cover all technical disciplines in Makerere University as long as the research questions align with the instructive research agenda themes above. Particular attention will be paid to unfunded priorities, those for which funding has been inadequate, or for which available funding only covers one or a few of the components needed to inform development initiatives in a holistic way. This grant is not primarily meant to supplement existing research projects that already have funding from other sources. However, researchers can apply on the platform of existing projects if they provide a strong justification that there are important funding gaps in the current research project and the added deliverables expected from the additional support to the existing research effort. This grant also emphasizes a multi-sectoral approach. Research groups are therefore encouraged to work with other sectors that complement their technical focus.
A4. Categories and size of grants to be issued:
Grants will be issued in the following categories:
The R&I Grants Management Committee reserves the right to determine/change the number and size of awards based on prevailing circumstances informed by demand, quality of applications, availability of funds and level of utilization of funds by grantees. 50% of all awards will go to research or ecosystem strengthening projects while 50% will go innovation-based projects.
**Experience from earlier RIF calls showed that most applicants (Over 50%) target Category 1 which creates a lot of competition and many otherwise good proposals being un-funded. Applicants for RIF-4 are encouraged to consider all categories.
*** Junior Faculty Researchers are STRONGLY encouraged to apply. (Junior Faculty are not defined by age, but by rank and research experience. They are specifically defined as researchers at the rank of Lecturer or below and researchers with less than 5 years of experience in research/innovation or less than 2 years as independent researchers/innovators, or have never been PIs for a research/innovation project greater than US$ 100,000 (or 365 Million Uganda Shillings).
The National Council for Higher Education (NCHE) is mandated under Section 4(b) of the Universities and Other Tertiary Institutions Act 262, to promote and develop the processing and dissemination of information on higher education for the benefit of the public. In line with this mandate, NCHE has consistently advanced scholarly discourse in higher education through The Uganda Higher Education Review Journal, published semi-annually in May and November.
It is my privilege to present to you Volume 12, Issue 1 (November 2024) of the journal, now available electronically via DOI: 10.58653 and with ISSN 1813-2243 (print) and 2958-5473 (online). The articles in this issue embody a profound commitment to rigorous inquiry, intellectual curiosity, and scholarly excellence.
This edition explores critical themes, including:
Financing and Investment in Higher Education.
The Adoption of Emerging Technologies in the Digital Transformation of Higher Education.
Improving Access and Inclusivity in Higher Education in Uganda: Addressing the Nation’s Low Gross Enrolment Ratio.
The Role of the Private Sector in Enhancing Graduate Skills and Employability through Technology Innovation.
I sincerely appreciate the contributors whose unwavering dedication to their fields has enriched the publication. I also acknowledge the exceptional efforts of the authors, NCHE staff and Management, the editorial team, and the reviewers. Their expertise and commitment have been instrumental in ensuring the quality and integrity of the research presented in this volume.
Professor Mary J. N. Okwakol EXECUTIVE DIRECTOR/EDITOR-IN-CHIEF
Godwin Anywar, cohort 6, Makerere University, attended the 2024 World Science Forum that took place on November 20 – 23, 2024 in Budapest, Hungary. At the forum, he participated in a side event: ‘Trust in Science’, a workshop for early career researchers organized by the Global Young Academy (GYA) and the InterAcademy Partnership (IAP).
On November 26 – 28, 2024, he attended the twentieth annual meeting of the African Science Academies (AMASA 2024) and the General Assembly of the Network of African Academies of Sciences (NASAC), in Algiers, Algeria. He presented on ‘Promoting Science Diplomacy for Sustainable Development in Africa’ as one the co-leads of the Science Diplomacy in Africa working group of the Global Young Academy’.
Godwin also participated in the Uganda Text Book Academic and Non-Fiction Authors Association (UTANA)- hybrid symposium on authorship capacity where he moderated a panel session on Artificial Intelligence (AI) and academic authorship. With the theme ‘Capacity building for academic and nonfiction authorship for Africa’s Transformation’ the symposium took place from November 14 -15, 2024 in Kampala, Uganda.
Additionally, he attended and moderated a session on the regulation and registration of herbal medicinal products (HMP) in African countries. Organized by the Society for Medicinal Plants and Natural Products Research (GA) in collaboration with PharmaConnect Africa NPC and The Natural Products Research Network for Eastern and Central Africa (NAPRECA), the session was part of an eSeminar series ‘Regulation of Natural Products – a Global Challenge’.
The emergence of multidrug resistant Candida species to available drugs has led to renewed interest in the use of herbal medicines globally. This study scientifically verified antifungal effectiveness of five commonly used plant species in Pader district, against selected pathogenic candida strains.
Methods
Powdered roots of Momordica foetida, Sansevieria dawei and Distimake dissectus; and stem barks of Khaya anthotheca and Mitragyna rubrostipulata were extracted sequentially using petroleum ether and methanol, respectively; and total water extraction at 24.4 °C (maceration), 60 °C (decoction) and boiling water at 87 °C (hot water infusion). Extracts and their combinations, positive controls (amphotericin B, and fluconazole) and negative control (80% dimethyl sulfoxide, verified to be tolerable concentration to the tested Candida species) were screened and verified for their antifungal activity against Candida albicans (ATCC: American Type Culture Collection reference strain 10231, ATCC 90028, 0770a and 0796), C. glabrata (VVc 004, ATCC 2950) and C. tropicalis (ATCC 750 and 0210) using agar well diffusion and broth micro-dilution, respectively.
Results
Aqueous extract (24.4 °C) of M. rubrostipulata (ZOI: 18.00 ± 1.00 to 38.33 ± 0.17; MIC: 3.13 ± 0.00 to 20.83 ± 4.17; MFC: 12.50 ± 0.00 to 200.00 ± 0.00), methanol extract of K. anthotheca (10.11 ± 0.31 to 15.11 ± 0.65; 1.04 ± 0.26 to 12.50 ± 0.00; 12.50 ± 0.00 to 100.00 ± 0.00), and combination of aqueous extract (60 °C) of D. dissectus + methanol extract of K. anthotheca (7.89 ± 0.26 to 19.67 ± 0.37; 0.78 ± 0.00 to 50.00 ± 0.00; 12.50 ± 0.00 to 200.00 ± 0.00) exhibited broad spectrum antifungal activities and were fungistatic against all tested Candida species, which comprised 8 clinical/control and susceptible/resistant strains. None of the conventional drugs used demonstrated broad spectrum antifungal activity across all tested Candida species/strains.
Conclusion
Methanol extract of K. anthotheca, aqueous extract (24.4 °C) of M. rubrostipulata, and combination of aqueous extract (60 °C) of D. dissectus + methanol extract of K. anthotheca could be effective in the treatment of candidiasis. They demonstrated potential broad spectrum antifungal activity against different species and strains of tested Candida than the fluconazole and amphotericin B drugs. Their fungistatic nature showed their ability to inhibit fungal growth. Hence, these extracts/extract combination can offer better treatment option for candidiasis if they are standardized and also their active curative compounds isolated and made into antifungal drugs.
Health1 week ago
Humanities & Social Sciences2 weeks ago
General1 week ago
General2 weeks ago
Agriculture & Environment2 weeks ago