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IDI CAPA-CT II Partners-UNITO Publish Method Quantifying Experimental COVID-19 Drug in Blood Samples

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University of Turin (UNITO) investigators, partners on the Makerere University Infectious Diseases Institute (IDI)-led consortium CAPA-CT II, are the first to openly publish a method for quantifying remdesivir in blood. Remdesivir has recently received authorisation for emergency use in the US and European Union for patients with severe forms of COVID-19.

The method has been fully published in the July 01, 2020 edition of the Journal of Antimicrobial Chemotherapy and it was selected as an Editors Choice article. Turin investigators and collaborators from IDI and University of Liverpool reported on the use of an ultra-high performance liquid chromatography assay to measure remdesivir and its active form in blood. https://academic.oup.com/jac/article/75/7/1772/5828362  

Dr Lamorde, Project Coordinator of the CAPA-CT II consortium says “This tool will enable clinical researchers worldwide to better understand how this important drug works and how it may be affected by other drugs patients may be taking. We are excited because this is the first step in our efforts to conduct a study to understand how to ensure we use the right dose of remdesivir in patients that are already taking antiretroviral drugs.” . Dr Lamorde and colleagues on the CAPA-CT II have an ethics approved protocol to investigate whether the quantity of remdesivir in patient blood samples is influenced by the presence of antiretroviral drugs. 

https://clinicaltrials.gov/ct2/show/NCT04385719

The CAPA-CT II project is part of the EDCTP2 (European and Developing Countries Clinical Trials Partnership 2) programme supported by the European Union.

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Makerere Medical Journal: Golden Jubilee Edition 2022

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Cover Page of the Makerere Medical Journal Golden Jubilee Edition 2022.

It’s with great pleasure that I welcome you to the Golden Jubilee edition of this phenomenal journal. Yes, The Makerere Medical Journal marks 50 years of publication with this year’s edition and all this has been made possible by the endless efforts and contributions of the Makerere University College of Health Sciences Staff and students because without your research submissions and financial support, the journal wouldn’t have made it this far. To you reading this, thank you for contributing to the sustainability of this great project, year in year out.

Here’s a quote to ponder on as you delve into this year’s well-crafted articles and it’s by Zora Hurston (1891-1960), “Research is formalized curiosity. It is poking and prying with a purpose.” And doesn’t that just define our purpose as researchers?!

This edition’s articles cover pertinent topics ranging from Antimicrobial Stewardship, COVID-19 interventions, Oral Health amongst others. It also features student projects, write-ups on student-led organizations and societies that are making a difference in the life of a health sciences’ student and many more interesting writings. Featured in this issue are international manuscripts from countries like Nigeria and we were also honored to work with other universities within the country and feature some of their students’ articles.

I would like to extend my most sincere gratitude to my team of editors that engaged in a rigorous peer review process to ensure that the articles published are up to standard. As the editorial team, we are quite pleased to see the number of undergraduates involved in research steadily increasing and all the efforts that have been put in by the different stakeholders to see this happen are commendable.

With that said, I hope you enjoy every second of your read!!!

LINDA ATULINDA,
MBChB IV

EDITOR-IN-CHIEF,
Research and Writers’ Club 2021-2022

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Call for Applications: HEPI Masters Support Fellowship

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Panelists L-R: Professor Elsie Kiguli-Malwadde, Professor Francis Omaswa, Professor Jehu Iputo and Professor Joel Okullo at the HEPI-ACHEST Health Professions Education Symposium, 17th June 2022, Makerere University.

Applications are invited for the Health Professional Education Partnership Initiative (HEPI-SHSSU) Masters fellowship programme support from postgraduate students of:

  • Makerere University College of Health Sciences (MakCHS)
  • Kabale University School of Medicine
  • Clarke International University
  • Faculty of Health Sciences, Busitema University

The programme will support graduates in their final year of training leading to the award of a Masters degree on any of the Master’s graduate training programs at the stated University for a maximum of 19 successful candidates.

The closing date for the receipt of applications is 30th September 2022.

Inquiries and Applications must be submitted to hepishssu@gmail.com

See attachment for more details 

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Call for Applications: Faculty Research Training

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The Principal MakCHS-Prof. Damalie Nakanjako (6th R), Prof. Sarah Kiguli-PI HEPI (R), Prof. Francis Omaswa-ED ACHEST (8th R), Dr. Safina Museene-MoES (5th R), Prof. Rhoda Wanyenze (3rd R), Prof. Joel Okullo (9th R), Prof. Josephine Namboze (7th R), Prof. Elsie Kiguli-Malwadde - ACHEST (2nd R) and other Health Experts at the Symposium on 17th June 2022, MakCHS, Makerere University.

Applications are invited from faculty at Makerere University College of Health Sciences, Kabale School of Medicine, and Clarke International University to undertake training in research.

Limited research funding will be available for research focusing on community-based, clinical, operational, health professions education, epidemiological, biomedical, and research in Communicable Diseases (e.g. HIV/AIDS, malaria, tuberculosis, etc.) or non-communicable diseases of importance to Uganda.

Up to 15 applicants will be selected and they will undergo a brief (2 days) didactic training in research proposal development prior to embarking on their research projects. Up to 4,000 US dollars per applicant (depending on budget) will be available to support the research.

The closing date for the receipt of applications is 3rd October 2022.

Inquiries can be forwarded to the PI, HEPISU Program on hepishssu@gmail.com

See attachment for more details

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