Research
Africa’s Future through Research and AI: Makerere Hosts ARUA 5th Biennial Conference
The Minister for Science, Technology and Innovation Information, Hon. Dr. Monica Musenero Masanza has officially opened the 5th African Research Universities Alliance (ARUA) Biennial International Conference on Research, Innovation and Artificial Intelligence, held on October 29, 2025. Hosted by Makerere University, the three-day conference has drawn together distinguished guests including Vice Chancellors and their deputies from universities under the ARUA, alongside leading scholars and practitioners in Science, Technology and Innovation. The gathering comes at a momentous time as ARUA celebrates its 10th anniversary—an occasion that underscores the alliance’s growing impact on advancing research and collaboration across the continent. Over the course of the conference, participants will deliberate on how research, innovation and artificial intelligence can be harnessed to address Africa’s most pressing challenges and drive sustainable transformation.
Addressing Africa’s Scientific Renaissance
Hon. Dr. Monica Musenero, opened the conference with a compelling call for Africa to seize its moment in the Fourth Industrial Revolution. She reflected on the continent’s history of disruption—from the slave trade to colonization—that interrupted the continuity of African innovation, noting how earlier generations independently developed technologies, smelted iron, and applied natural therapeutics without formal laboratories. Hon. Musenero urged African scientists, researchers, and universities to reclaim this legacy by transforming knowledge into practical solutions that address real-world challenges, create jobs, and drive economic growth.
She emphasized that the role of science must extend beyond academic publications and ivory towers, stressing the need for inventions, industrialization, and commercialization of research outcomes. Highlighting Uganda’s progress, she pointed to innovations in electric vehicles, pharmaceuticals, and agriculture, as well as initiatives to harness AI and digital technology to benefit local economies. She challenged researchers to align their work with national priorities, protect intellectual property, and translate knowledge into tools, industries, and enterprises that uplift communities. Hon. Musenero concluded by urging African scientists to embrace challenges as opportunities, enter the “Evil Forest” of innovation with courage and resilience, and ensure that Africa no longer remains a passive observer in global technological advancement but a leader shaping its own development trajectory.
Dr. Lorna Magara, Chairperson of the Makerere University Council on her part described the gathering as a convergence of visionaries, dream builders, and custodians of Africa’s future. She emphasized that the theme of the conference, Research, Innovation, and Artificial Intelligence for Africa’s Transformation, called for a shift from consuming knowledge to creating and exporting it, positioning Africa at the center of global development.
Dr. Magara highlighted Makerere University’s initiatives, including the Makerere University Research and Innovation Fund (MakRIF), the AI and Data Science Research Center, and the Innovation Pod, as examples of how African universities can drive societal transformation when innovation is pursued with vision and intentionality. She also underlined the importance of collaboration through ARUA, noting that technology must serve humanity and be guided by African values of ethics, community, dignity, and shared prosperity. Pointing to Africa’s young population as a key engine of creativity and growth, Dr. Magara called on leaders and researchers to build ecosystems that empower scholars, inspire innovations that uplift communities, and forge partnerships to accelerate the continent’s progress.
The Vice Chancellor of Makerere University, Professor Barnabas Nawangwe, welcomed delegates to the Conference, expressed gratitude for Makerere’s role as a pioneer member of the alliance and paid tribute to the visionaries who laid its foundation. Speaking from the historic Main Hall—where Africa’s early independence leaders once debated the continent’s future—Professor Nawangwe reflected on how today’s struggles have shifted from political emancipation to scientific, technological, and economic liberation. He emphasized the urgent need to address Africa’s pressing challenges, including population growth, health, governance, and the transformative potential of artificial intelligence. Highlighting Uganda’s commitment to science, he cited the government’s support to Mak-RIF and the appointment of a scientist-led Ministry for Science, Technology, and Innovation as milestones of progress. He added that under the stewardship of strong leaders such as Dr. Lorna Magara and Hon. Dr. Monica Musenero, Makerere has received over $8 million annually in research funding, fostering groundbreaking innovations by students, faculty, and community innovators. Professor Nawangwe called for sustained collaboration, increased investment, and shared resolve to harness Africa’s knowledge and innovation for true emancipation.
A call to prepare early and act decisively for AI
The Secretary General of ARUA, Professor John Owusu Gyapong, delivered an insightful overview of the 5th Biennial International Conference, highlighting the urgency for Africa to leverage AI and research to transform its social, economic, and political landscape. He observed that while the continent continues to grapple with challenges such as poverty, unemployment, health crises, and governance gaps, artificial intelligence presents a unique opportunity to accelerate progress towards Africa’s Agenda 2063 and the Sustainable Development Goals.
Professor Gyapong emphasized the potential of AI to enhance research efficiency, drive innovation, and address pressing issues in agriculture, health, education, and governance. He also underscored the need for Africa to develop data infrastructure, ethical frameworks, and equitable access to AI tools. Outlining the conference program, he noted that discussions would center on building AI capacity in higher education, strengthening university–industry collaboration, and advancing responsible AI ecosystems. Concluding with an African proverb, he reminded participants that “you cannot fatten a goat on the market day,” urging institutions to prepare early and act decisively for Africa’s transformation.
In his address, the Chairperson of the ARUA Board, Prof. Sizwe Mabizela, paid tribute to the visionary leaders who founded ARUA and commended its founding Secretary General, Professor Ernest Aryeetey, for his exceptional leadership in strengthening the alliance across the continent. Professor Mabizela emphasized the importance of collaboration among African universities and their global partners in addressing the complex challenges facing humanity—ranging from climate change and pandemics to inequality and technological disruption. He called for stronger, sustainable international research networks that enable knowledge exchange, innovation, and institutional growth, allowing African universities to become central contributors to global progress. Expressing appreciation to Makerere University for hosting the conference, he applauded the organizers, keynote speakers, and participants for their dedication to advancing Africa’s research and innovation agenda. He concluded with optimism, affirming that through collaboration, shared purpose, and resilience, Africa’s future remains bright with promise and possibility.
In his virtual address, Professor Tshilidzi Marwala, Rector of the United Nations University, urged Africa to harness its vast potential as the world’s youngest and fastest-growing continent. He reflected on the continent’s unique position to redefine its development path through courage, collaboration, and conviction. Acknowledging the challenges of climate change, health inequities, educational disparities, and economic inequality, he emphasized that Africa’s research institutions are already generating groundbreaking, context-driven innovations. Drawing inspiration from Robert Frost, Professor Marwala noted that Africa stands at a crossroads—and that the choices made today will shape its destiny. He called for bridging the gap between knowledge and implementation, affirming that with collective effort and optimism, “nothing can stop us now.”
During the conference, Makerere University signed a Memorandum of Understanding (MoU) with Astria Learning, a global education technology company dedicated to developing impactful, flexible, and accessible e-learning solutions. Speaking at the signing ceremony, Astria Learning’s CEO Dr. Jeff Bordes highlighted how artificial intelligence is revolutionizing education and underscored the partnership’s role in shaping the future of learning in Africa. He shared that, recognizing AI’s potential to redefine teaching and research, Astria pivoted its focus from traditional software development to AI-driven educational technologies. Through this collaboration, Makerere University and Astria Learning will establish an AI e-Campus aimed at accelerating postgraduate education and supporting the African Union’s goal of producing one million PhDs by 2035. Dr. Bordes noted that AI tools such as automated grading systems, intelligent tutoring, and adaptive content creation will empower lecturers to manage larger cohorts efficiently without compromising quality. Expressing gratitude to Makerere University’s leadership, he affirmed Astria Learning’s commitment to transforming higher education and building global capacity through technology.
A Host’s heartfelt appreciation
Professor Robert Wamala, Director of Research, Innovation and Partnerships at Makerere University and Chairperson of the Local Organizing Committee expressed deep gratitude to the participants, partners, and sponsors whose collaboration made the event possible, and extended a special welcome to international guests visiting Uganda for the first time. Professor Wamala described the conference theme as both timely and forward-looking, noting that AI is reshaping how societies live, learn, and develop.
He emphasized that for Africa, this technological revolution presents not just an opportunity to catch up, but to lead — anchored in strong research, ethical practices, and a shared vision for sustainable development. Appreciating the dedication of his organizing team, he encouraged participants to use the conference as a platform for learning, co-creation, and collaboration across nations, reminding them that while artificial intelligence is powerful, “human intelligence, ethics, and purpose must lead the way.”
Uganda’s latest national HIV survey reveals lower viral suppression among adolescents and young adults living with HIV than among older adults, even as the country records substantial improvements in controlling the virus. The findings come from Uganda Population-Based HIV Impact Assessment (UPHIA 2025), a national household survey examining HIV prevalence and whether people living with the virus know their status, receive treatment, and achieve viral suppression.
Releasing the preliminary UPHIA 2025 findings at the Uganda Media Centre on 1 October 2026, Minister of Health Hon. Dr. Chris Baryomunsi called for earlier prevention and testing, particularly among adolescent girls and young women, alongside support for treatment adherence. “We must reach out to the young people, ensure that they have information, they test, take treatment, and adhere to the treatment guidance,” he urged.
Hon. Baryomunsi recalled how fear had discouraged testing during his university years: “I remember when we were at university, we went for testing at the university hospital. We sat there for three hours. Some of us left without even testing because it was scary.” Today, he explained, “even if you test HIV positive, you can be initiated on treatment, and you live normally like the rest of those who don’t have HIV.”
UPHIA 2025 was locally led under the Ministry of Health’s overall leadership, with Makerere University School of Public Health serving as the prime implementer, a role ICAP at Columbia University held in the previous two surveys. The Uganda Bureau of Statistics led sampling, while the Uganda Virus Research Institute and National Health Laboratory and Diagnostic Services led laboratory operations. Regional referral hospitals and local governments supported implementation, and the U.S. government provided US$10 million through PEPFAR, along with technical assistance from the U.S. CDC.
UPHIA collected data from July to September 2025 among people aged 15 and above, including those outside routine treatment services. Of 6,283 eligible households, 94.4% completed interviews. Researchers interviewed 13,801 people and tested 13,477 for HIV.
Testing followed Uganda’s national algorithm, with laboratory confirmation of positive samples, viral-load measurement, and checks for antiretroviral medicines to establish treatment use. Researchers weighted the estimates to account for the sampling design. Participants received counselling and results, and those who tested positive were referred for treatment.
Hon. Baryomunsi thanked participants and their families for welcoming survey staff and contributing their time, information and samples, without which the national evidence would not have been available.
National progress and the youth gap
The survey estimated HIV prevalence, which means the proportion of people living with HIV, at 5.9% among those aged 15 and above, corresponding to about 1.496 million people in this age group nationwide. Prevalence was 7.3% among women and 4.1% among men, ranging from 1.3% in Karamoja to 8% in the South Western region.
Among people aged 15 and above living with HIV, 86% had achieved viral suppression, meaning a low amount of HIV in the blood, measured in UPHIA as fewer than 1,000 copies per millilitre. Suppression stood at 69.3% among adolescents and young adults aged 15–24 living with HIV, compared with 89.9% among those aged 50 and above. These estimates cover people living with HIV regardless of whether they know their status or receive treatment.
HIV prevalence among people aged 15–24 was 1.5%, including 2% among young women and 1% among young men. Among young women, prevalence was 1.3% at ages 15–19 and 2.8% at ages 20–24. These differences support attention to earlier prevention and testing, although they do not establish when infections occurred.
The highest prevalence estimates occurred among middle-aged adults: 15.7% among women aged 40–44 and 11.7% among men aged 45–49. Lower suppression among young people therefore requires attention alongside the higher HIV prevalence among middle-aged adults. Comparing the same age group across both surveys, viral suppression among people aged 15–64 increased from 74.9% in 2020–21 to 86.1% in 2025, while HIV prevalence remained at 5.9%.
Diagnosis and the path to 2030
The treatment results identify diagnosis as the main national gap. Among people aged 15 and above living with HIV, 85.3% knew their status. Of those aware, 99.1% were receiving treatment; among those receiving treatment, 96.5% had achieved suppression.
The 95-95-95 targets aimed for 95% of people living with HIV to know their status, 95% of those diagnosed to receive treatment, and 95% of those receiving treatment to achieve viral suppression by 2025. Among people aged 15 and above, Uganda exceeded the treatment and suppression targets, while diagnosis remained below target. UNAIDS’s Global AIDS Strategy 2026–2031 retains these targets towards ending AIDS as a public health threat by 2030.
According to WHO, viral suppression protects health and helps prevent HIV transmission. Uncontrolled HIV weakens the immune system, increasing the risk of serious illness. With continued treatment as prescribed, sexual transmission risk is negligible when HIV remains suppressed but detectable, and zero when undetectable. The Uganda AIDS Commission estimated over 34,000 new HIV infections in 2025, underscoring the importance of early diagnosis, timely treatment, and sustained suppression alongside other prevention measures.
The demographic stakes are substantial. People aged 15–24 constituted 21.2% of Uganda’s population in the 2024 census. The country’s Fourth National Development Plan, covering 2025–2030, prioritises a healthy, knowledgeable, skilled and productive population and reducing HIV through primary health care. Protecting young people’s health, therefore, supports their participation in education, work, and national development; UPHIA helps identify where services need greater attention.
Turning evidence into action
The study’s conclusions identify three priorities: sustain treatment outcomes, find people unaware of their status, and improve suppression among younger people. Permanent Secretary Dr. Diana Atwine connected the findings to the Ministry’s planning.
“We do believe that these results are a true reflection of what is happening in our country as far as the HIV status is concerned, and we do believe that it will give us a very clear direction and the roadmap that we are going to take in the next five years to target and to get our targets achieved.”
Acting on these priorities requires funding for services and research. Hon. Baryomunsi outlined plans to target resources where needs are greatest, strengthen district services and align partner support with government priorities. Responding to journalists’ questions, he noted the government’s intention to increase domestic funding for the HIV response, including research.
“The HIV/AIDS response, including research and surveys such as this one, has largely been funded by partners in the past. The government of Uganda is committed to allocating more resources from our domestic budget to support the response and research,” he noted.
For the first time in the UPHIA series, the survey assessed selected noncommunicable disease indicators among people aged 15 and above: 15.5% had elevated blood pressure, 24.8% were overweight or obese, and 0.9% had raised random blood glucose. These screening findings align with the Ministry’s integration agenda and Hon. Baryomunsi’s call to bring HIV and chronic care services together to address people’s wider health needs.
Speaking at the release of the preliminary results, U.S. Embassy Chargé d’Affaires Mikael (Mika) Cleverley described UPHIA 2025 as the first Population-Based HIV Impact Assessment worldwide fully led and implemented by the country itself.
“The study was led by Ugandan scientists, Ugandan managers, Ugandan public servants, Ugandan field teams, from design to data collection to analysis. And this is what two decades of focused strategic U.S. foreign investments in the public health sector was meant to produce, is to reinforce Ugandan leadership and Ugandan-led efforts.”
At the survey launch on 29 May 2025, MakSPH Dean Prof. Rhoda Wanyenze highlighted the partnership’s contribution: “The partnership between Makerere University and CDC has not only helped build national capacity in surveillance and epidemiology, but has also strengthened our ability to lead high-quality, large-scale national surveys.”
The Dean added: “After two decades of joint work, we are proud that UPHIA is now a fully Ugandan-led effort. This is critical to the sustainability of the skills and knowledge generation to inform our local response.”
UPHIA 2025 shows how far Uganda’s HIV response has advanced and where gaps remain. As the country works towards ending AIDS as a public health threat by 2030, reaching young people with testing, treatment, and continued care will be essential to extending those gains.
Read the full UPHIA 2025 summary results here:
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