In a decisive step toward ending HIV as a public health threat by 2030, Uganda on Thursday, May 29, 2025, officially launched the third Uganda Population-based HIV Impact Assessment (UPHIA 2025) survey, a nationally representative household study expected to provide updated measurements on the status of the HIV epidemic by the end of the year.
The effort is led by Uganda’s Ministry of Health (MoH), with technical assistance from Makerere University School of Public Health (MakSPH), Uganda Bureau of Statistics (UBOS), Uganda Virus Research Institute (UVRI), and the U.S. Centers for Disease Control and Prevention (U.S. CDC), funded by the U.S. government through PEPFAR.
The Population-based HIV Impact Assessment (PHIA) surveys were first launched in 2014 as a global initiative at the International Center for AIDS Care and Treatment Programs (ICAP), based at Columbia University’s Mailman School of Public Health. Supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), through the U.S. CDC, the surveys have been conducted in at least 15 high-burden countries globally, including Uganda.
Led by national Ministries of Health, the PHIA surveys provide robust, population-level data on HIV prevalence, incidence, and viral suppression, offering a clear picture of epidemic trends and the effectiveness of national responses. They are designed to track progress, identify persistent gaps, and inform strategies to reach epidemic control, in line with global targets, including the fast-approaching goal of ending AIDS as a public health threat by 2030.
At the centre, the Minister of Health, Dr. Jane Ruth Aceng, and the U.S. Ambassador to Uganda, William W. Popp, together with key dignitaries and the study field team, during the launch of UPHIA 2025 in Kampala on 29 May 2025.
In Uganda, this survey was first rolled out between August 2016 and March 2017. The second followed in February 2020 but was disrupted by the COVID-19 outbreak, continuing through to March 2021. Both rounds were supported by ICAP at Columbia University, which provided technical assistance to strengthen data collection systems, improve laboratory infrastructure, and build national capacity to design, implement, and analyse the two national HIV surveys.
What sets UPHIA 2025 apart is the shift in technical leadership to Ugandan institutions for this third survey, reflecting local capacity to lead rigorous, high-quality public health research. For UPHIA 2025, Makerere University School of Public Health, in partnership with the Uganda Bureau of Statistics and the Uganda Virus Research Institute, is providing technical leadership to the Ministry of Health, alongside U.S. CDC. Implementation began with initial recruitment and training of over 300 field teams that begun on May 19, 2025, ahead of their nationwide deployment for data collection starting this June.
The first survey (UPHIA 2016) was an important milestone in informing Uganda’s national HIV response. This survey, concluded in 2017, measured, among things, the viral load suppression at the population level and provided household-based HIV testing and counselling, with results returned to participants and those who tested positive referred to care. The survey also assessed HIV incidence, HIV and syphilis prevalence, as well as hepatitis B infection rates. These findings would offer nationally representative data to track Uganda’s progress in controlling the HIV epidemic at both national and regional levels.
The next survey, UPHIA 2020, building on past success, was again executed with technical leadership from Columbia University’s ICAP, working with Uganda’s Ministry of Health alongside UVRI, UBOS, regional referral hospitals, local governments, and the U.S. CDC. It offered useful insights that showed encouraging progress, indicating that up to 88% of people living with HIV in Uganda at the time knew their status, 98% of them were on treatment, and 90% had achieved viral suppression. These results reflected momentum toward the UNAIDS global 95-95-95 targets, ensuring that most people living with HIV are diagnosed, treated, and have the virus under control, and advancing the broader goal of ending the epidemic by 2030.
Since the release of these findings nearly five years ago, which helped shape national HIV programming in Uganda, the country has made notable progress, but challenges remain. The UPHIA 2020 findings reported major gaps in testing coverage, particularly among young people and men. The results were also instrumental in identifying service delivery shortfalls and guiding decisions on resource allocation, program design, and policy. Yet today, Uganda remains one of the most heavily burdened countries in the world, with over 1.5 million people living with HIV and over 50,000 preventable new infections recorded per year.
The Minister for Health, Dr. Jane Ruth Aceng, launching the UPHIA 2025 survey in Kampala on May 29th, 2025.
It is this trend that Uganda’s Ministry of Health is working urgently to reverse. Launching UPHIA 2025 at the Ministry’s headquarters in Kampala on May 29, 2025, amidst great hope and expectation among the participants, Uganda’s Minister of Health, Dr. Jane Ruth Aceng Ocero, noted that the long-anticipated and previously delayed survey had arrived at such a critical moment. She welcomed UPHIA 2025 as both a measure of the country’s resilience and a guide for the final stretch toward ending AIDS by 2030, now just a few years away.
“The UPHIA 2025 survey comes at a strategic time to help us recalibrate and refocus our efforts,” the Health Minister said, underscoring the importance of its outcomes. “This will be Uganda’s final population-based HIV survey before 2030, the target year for ending AIDS as a public health threat. The findings will serve as a baseline for tracking our progress toward this national and global goal. They will also guide the next phase of strategic planning, ensuring that the final push toward 2030 is grounded in robust and reliable data.”
This third round of the survey will be carried out in 6,685 randomly selected households across the country. The exercise will involve interviews with approximately 15,000 individuals aged at least 15 and selected through a national household listing by UBOS. Of those, around 14,980 are expected to provide blood samples for HIV testing and analysis of viral suppression and other health indicators. The survey will also include interviews with 1,300 children and adolescents aged 10 to 14, though no blood draws will be taken from this group. Participation is voluntary, free of charge, and requires consent from the head of each household.
MakSPH’s Assoc. Prof. Fredrick Makumbi, the Principal Investigator for UPHIA 2025 survey, consults with MoH’s Commissioner for Human Resource Management, Ms. Annet Musinguzi, during the kick-off of training of UPHIA 2025 field teams at MakSPH New Auditorium on 19th May, 2025.
Dr. Aceng explained that beyond providing updated estimates of HIV prevalence, incidence, and viral load suppression, and examining regional and demographic disparities, the survey, which will cover the rest of the year, will include a qualitative post-survey assessment component to gather insights from people living with HIV, particularly those not virally suppressed, to understand their challenges and strengthen support services. Also, for the first time, this survey will assess the burden of non-communicable diseases among people living with HIV and include focused interviews with adolescents aged 10 to 14 in Mid-North and Mid-Eastern Uganda, where viral suppression was reported to be lowest in UPHIA 2020.
These activities are made possible thanks to the development support from the U.S. government, which invested $10 million (about UGX 37 billion) for this survey. Speaking at the UPHIA 2025 launch, U.S. Ambassador to Uganda William W. Popp noted that the United States has partnered with Uganda for over three decades to help people live longer, healthier lives;
“The bulk of our annual support, approximately $500 million this year, is dedicated to health programs, making the U.S. government the largest single provider of health assistance to Uganda,” the Ambassador said. He added, “Through PEPFAR, the United States has played a major role in Uganda’s progress toward ending HIV as a public health threat. Since 2003, when Uganda became one of the first countries to implement the program, we have invested nearly three billion dollars—almost 11 trillion Uganda shillings—in HIV prevention, care, and treatment services, saving millions of lives and making both our countries safer from HIV.”
At the UPHIA 2025 launch, Ambassador Popp emphasised the enduring U.S.-Uganda partnership in advancing public health.
With the benefit of hindsight, Uganda’s early encounter with HIV in the 1980s marked the beginning of one of the region’s most severe epidemics. But over the decades, a determined national response, driven by political leadership, community mobilisation, collaboration and global support, has delivered measurable progress. In the recent past, adult HIV prevalence fell from 7.2% in 2010 to 5.1% in 2023. Among women, it declined from 8.5% to 6.6%, and among men from 5.8% to 3.6%. AIDS-related deaths dropped from 53,000 to 20,000 over the same period, with female mortality declining by 66% and child deaths by 77%.
All these gains, amidst the challenge, go to show what is possible with sustained commitment. What is more, throughout this long journey of Uganda’s battle with eradicating HIV, Makerere University School of Public Health has played a pivotal role. From the early work of Prof. David Serwadda, whose ground-breaking research during the initial detection of HIV helped shape Uganda’s early response, to last year’s 2024 landmark Purpose 1 study on the twice-yearly injectable Lenacapavir that proved 100% efficacy in preventing HIV infection, MakSPH has remained at the forefront of innovation, evidence generation, and policy influence.
That legacy continues today, with the School providing technical leadership to the Ministry of Health in the implementation of UPHIA 2025. At the launch, MakSPH Dean Prof. Rhoda Wanyenze expressed pride in the School’s role as a trusted partner in Uganda’s fight against HIV and other public health challenges. She noted that for over 70 years, during which the School has existed, MakSPH has helped shape the country’s public health landscape through rigorous research, training, and policy support, anchored by a strong, long-standing partnership with the Ministry of Health and partners.
At the UPHIA 2025 launch, Prof. Rhoda Wanyenze highlights MakSPH’s legacy in shaping Uganda’s public health landscape through rigorous research and policy support.
She also noted that the collaboration between Makerere University and the U.S. CDC has helped build national capacity in surveillance and epidemiology, while also strengthening Uganda’s ability to lead high-quality, large-scale national surveys, asserting that:
“The partnership between Makerere University and CDC has not only helped build national capacity in surveillance and epidemiology, but has also strengthened our ability to lead high-quality, large-scale national surveys. After two decades of joint work, we are proud that UPHIA 2024–2025 is now a fully Ugandan-led effort. This is critical to the sustainability of the skills and knowledge generation to inform our local response.”
The survey builds on MakSPH’s experience conducting similar national studies, including those on tuberculosis, prison health, family planning, schistosomiasis, and non-communicable diseases such as the STEPS survey. It will leverage the School’s strong capacity in research and impact evaluation, both in Uganda and across the African region, with a firm commitment to delivering high-quality data guided by the same rigour and integrity that have defined our work over the years, Prof. Wanyenze affirmed.
Kampala — On Saturday, a car park on the campus of Makerere University in Kampala became the stage for a continental emergency response. Delegates, dignitaries and diplomats gathered in the tent outside the Infectious Diseases Institute (IDI), a research institute owned by the university, for the formal launch of the Continental Incident Management Support Team (IMST), a joint Africa Centres for Disease Control and Prevention (Africa CDC) and World Health Organization (WHO) operation racing to contain the Bundibugyo strain of Ebola sweeping through the Democratic Republic of the Congo and, increasingly, Uganda. After the ribbon-cutting, guests were led inside to tour the team’s new home at IDI’s McKinnell Knowledge Centre, where the command offices have now been set up.
Dr Chris Baryomunsi joins delegates for a group photograph at the IMST launch, Infectious Diseases Institute, Makerere University.
The numbers explain the urgency. As of 21 June, more than 1,000 confirmed cases and 269 deaths had been recorded across the two countries, the vast majority in Ituri Province in eastern DRC. Uganda’s tally stood at 20 cases and two deaths, almost all traced to cross-border movement from the DRC. Eighty-two health workers have been infected, 18 fatally, a toll that helped push the WHO to declare a Public Health Emergency of International Concern in May, mirrored days later by Africa CDC’s own continental emergency declaration.
Prof Henry Mwanaki Alinaitwe, Deputy Vice Chancellor for Finance and Administration at Makerere University, with the acting US Ambassador to Uganda and Prof Samuel Luboga, IDI board chair, at the IMST launch.
Until now, the international response has been coordinated remotely, a patchwork of video calls and scattered logistics that officials admit slowed decision-making. The Kampala launch marks a shift from that fragmented model to a single, physically co-located command centre housed at IDI’s McKinnell Knowledge Centre, bringing case management, surveillance, logistics and risk communication specialists under one roof. From there, the convoy of delegates moved on to Kajjansi, on the outskirts of Entebbe, for the formal activation of the IMST’s regional logistics hub, the facility tasked with staging and rapidly deploying protective equipment and medical supplies across the outbreak zone.
Dr Chris Baryomunsi inspects the newly activated IMST logistics hub at Kajjansi, near Entebbe.
For Uganda’s health minister, Dr Chris Baryomunsi, the symbolism was as important as the logistics. Speaking at the launch, he argued that no nation can consider itself protected until its neighbours are equally prepared, framing cross-border solidarity as an operational necessity rather than an aspiration. He also announced a new memorandum of understanding with the DRC establishing joint Ebola treatment centres and laboratory services in the border towns of Aru and Kasenyi, warning that outbreak response cannot succeed while transmission continues unchecked on one side of a shared frontier.
Dr Chris Baryomunsi speaks as the guest of honour at the launch of the Continental Incident Management Support Team, Infectious Diseases Institute, Makerere University.
The WHO’s regional emergency director, Dr Marie-Roseline Belizaire, described the unified command structure as transformative, saying it would pool resources across agencies, cut duplication and keep field decisions anchored to scientific evidence. Africa CDC’s Dr Tolbert Nyenswah confirmed the team, specialists in case management, infection prevention, logistics and contact tracing, has now relocated physically to Kampala to work closer to the epicentre. Eleven epidemic-prone African nations, including Rwanda, Burundi, Angola and the Central African Republic, are participating in the preparedness effort even though most have not registered a single case.
Dr Marie-Roseline Belizaire, WHO AFRO’s regional emergency director, speaks at the launch of the Continental Incident Management Support Team in Kampala.
For IDI and Makerere University, hosting the command centre carries weight beyond the immediate crisis. IDI’s executive director, Dr Andrew Kambugu, said the institute had provided a fully equipped space, now installed at the McKinnell Knowledge Centre, enabling real-time communication between field teams, regional governments and international partners in Geneva, and framed the moment as proof that academic institutions can engage directly with pressing societal problems rather than observe from the sidelines.
Dr Andrew Kambugu delivers welcome remarks at the launch of the Continental Incident Management Support Team, Infectious Diseases Institute, Makerere University.
That framing matters for a continent whose research infrastructure has often been treated as peripheral to its own health emergencies. By anchoring the IMST’s command function within a Ugandan public university rather than in a foreign capital, the launch signals a modest but symbolic rebalancing: an African-led institution taking custody of an African-led response. The day’s itinerary made the point physically as well as symbolically: from the ribbon-cutting in Makerere’s car park, to the tour of the new command offices, to the drive out to Kajjansi to switch on the logistics hub, delegates traced the full chain of the response they had just committed to running.
Dr Chris Baryomunsi poses with the IMST logistics hub team at Kajjansi, following the hub’s formal activation.
Fred Ouma is the Corporate Communications Specialist, Infectious Diseases Institute (IDI).
Every 4 July, the United States marks its independence. This year’s commemoration carries added significance as the country celebrates 250 years, offering partners across the world a moment to reflect on relationships built through shared purpose, investment and trust.
For Makerere University School of Public Health (MakSPH), that reflection leads to a long and productive partnership with the people and Government of the United States, spanning more than 35 years. Through U.S. Government agencies and programmes, the collaboration has supported MakSPH’s growth from a national public health training institution into a regional platform for evidence, leadership, health systems strengthening and public health preparedness.
Today, MakSPH stands at a defining point in its institutional journey. Tracing its roots to the introduction of preventive medicine in Makerere University’s then Faculty of Medicine in 1954, the School has grown into a leading public health institution in Africa, training more than 1,000 students across 12-degree programmes, working through district field training sites, contributing to national technical committees, and implementing research and capacity-building work across Uganda and more than 35 African countries.
Hon. Margaret Muhanga, then State Minister for Primary Health Care and Chief Guest, joins Makerere University leaders and partners in cutting the MakSPH@70 anniversary cake during the School’s 70th anniversary celebrations in December 2024.
Its work spans infectious diseases, maternal and child health, noncommunicable diseases, climate and health, digital health, injury prevention, universal health coverage and epidemic preparedness. While grounded in close collaboration with the Government of Uganda, especially the Ministry of Health, this reach has also been shaped by long-standing U.S. Government support. Reflecting on this shared history, MakSPH Dean Prof. Rhoda Wanyenze said the partnership has made a lasting contribution to public health capacity.
“For more than three decades, MakSPH has been privileged to work in strong partnership with the people and Government of the United States. We are grateful for this collaboration, which has made a major contribution to advancing public health training, research and practice in Uganda and across Africa. From the Master of Public Health programme to fellowships, enhanced surveillance, operational research, HIV and infectious disease work, regional networks, innovation, and programmes such as METS, this partnership has helped build the people, evidence and systems that support public health action,” Prof. Wanyenze said.
MakSPH Dean Prof. Rhoda Wanyenze speaks during the UPHIA 2025 launch in Kampala, highlighting MakSPH’s contribution to Uganda’s public health response through research, evidence and technical guidance.
Training Leaders for Uganda’s Health System
In 1994, as Uganda decentralised its administration and public services, the Institute of Public Health, now Makerere University School of Public Health, established the Master of Public Health (MPH) Full-Time programme in response to a clear workforce need for public health leaders who could manage district health systems, investigate outbreaks, conduct needs assessments and respond to emerging health challenges.
Prof. David Serwadda, Professor Emeritus at Makerere University and former Dean of MakSPH, recalls the programme was designed to fill a critical district-level leadership gap. “After a very strong needs assessment by Makerere University and the Ministry of Health, it was found that we needed to train a specific cadre of public health leaders for the districts,” he said. “We needed people with good management skills, people who could investigate an epidemic, do a needs assessment and respond to health challenges.”
Prof. David Serwadda speaks during a departmental retreat in Jinja in June 2026. He served as Director of the Makerere Institute of Public Health from 2003 to 2007 and as the first Dean of MakSPH from 2007 to 2009.
Established as a two-year programme, the MPH Full-Time was based on the Public Health Schools Without Walls model and became one of the earliest community-based public health graduate programmes in Africa. Developed through joint commitment by the Institute of Public Health, the Ministry of Health and the Rockefeller Foundation, and with technical support from the U.S. CDC, the programme placed students at district field sites to learn through apprenticeship while working on real public health problems. Other partners, including WHO and UNFPA, later provided scholarship support.
Three decades later, the MPH Full-Time programme remains one of MakSPH’s flagship contributions to Uganda and the region’s public health workforce. It has trained more than 1,000 public health professionals for leadership across districts, Ministry programmes, research, teaching, implementation and technical advisory work. Many graduates have gone on to serve as District Health Officers, commissioners, programme leaders, researchers, lecturers and public health specialists, strengthening Uganda’s health system leadership.
Fellowships That Strengthened Public Health Response
In 2002, MakSPH hosted the first direct cooperative agreement between Makerere University and the U.S. CDC, formalising the workforce development arm of the partnership. Under the Leadership and Investment in Fighting Epidemics (LIFE) initiative, the agreement launched the HIV/AIDS Fellowship Programme, which trained leaders for organisations working in HIV and AIDS. By 2014, the programme had produced more than 100 long-term fellows, more than 200 medium-term fellows, and over 3,000 short-course participants.
Graduates pose with then U.S. Ambassador to Uganda H.E. William W. Popp during the 10th graduation of Advanced Field Epidemiology Fellows and the 2nd graduation of Laboratory Leadership Fellows under the Uganda Public Health Fellowship Programme in January 2026.
The fellowship platform later transitioned into the Uganda Public Health Fellowship Programme and, through subsequent cooperative agreements in 2016 and 2021, expanded into the broader Public Health Workforce Development Programme. Led by the Ministry of Health through the Uganda National Institute of Public Health, and implemented with the U.S. CDC, districts and MakSPH, the programme now supports advanced field epidemiology, Frontline and Intermediate Field Epidemiology Training, and laboratory leadership.
Fellows are embedded within the Ministry of Health, districts and public health institutions, strengthening surveillance, outbreak investigation, HIV/TB programming, quality improvement, laboratory systems and health informatics. The Field Epidemiology Track has supported an average of about 37 active fellows, including 39 in 2024/2025. That year, fellows provided technical assistance to the Ministry and conducted 84 epidemiological studies and investigations, including work linked to Uganda’s Mpox response.
HIV Evidence That Changed Policy and Practice
UPHIA 2025 laboratory technicians undergo pre-deployment training at MakSPH, delivered with Uganda National Health Laboratory Services, ahead of field data collection on HIV and related health indicators across Uganda.
Uganda’s HIV crisis in the 1980s became one of the earliest tests of MakSPH’s public health mission. The wasting illness, then known as “Slim”, was reported in Rakai in the early 1980s and later identified as HIV/AIDS. Researchers at the Institute of Public Health, now MakSPH, helped advance understanding of the epidemic, with Prof. David Serwadda among the earliest physicians in Uganda to recognise and describe the disease.
That work grew into the Rakai Health Sciences Programme, established in 1989 through collaboration involving Makerere University, Columbia University, Johns Hopkins University, the U.S. National Institutes of Health (NIH) and partners. Over the decades, Rakai became a platform for research, surveillance, service delivery and training in communities deeply affected by HIV.
One landmark contribution showed that safe medical male circumcision reduced female-to-male HIV acquisition by about 60 per cent, helping inform HIV prevention policy in Uganda and globally. PEPFAR support also helped expand treatment in Rakai, where surveillance documented reduced mortality, lower HIV incidence, reduced orphanhood and improved community productivity.
The search for stronger prevention tools continued through MakSPH researchers, including Prof. Noah Kiwanuka, whose work in rural and fishing communities highlighted the need for better options for adolescent girls and young women. From 2022 to 2024, MakSPH managed the Makerere-Kalangala study site with UVRI-IAVI for the Gilead Sciences-led PURPOSE 1 trial, with Prof. Kiwanuka as Site Principal Investigator. The study contributed evidence on lenacapavir, a twice-yearly injectable now recognised as a major advance in HIV prevention.
Surveillance and National Decisions
Then Minister of Health Dr. Jane Ruth Aceng flags off UPHIA 2025 field teams in Kampala on 29 May 2025. The Ministry of Health-led survey is implemented with technical support from MakSPH and partners.
The partnership has also strengthened Uganda’s ability to measure the HIV epidemic and use evidence for national decisions. The Uganda Population-based HIV Impact Assessment (UPHIA) 2024/2025 is the country’s third national household-based HIV impact survey, commissioned by the Ministry of Health with technical support from MakSPH in partnership with UBOS, UVRI, and the U.S. CDC. After two earlier rounds supported by ICAP at Columbia University in 2016 and 2020, the current survey marks a shift to Ugandan leadership in implementation, analysis and use of evidence for the national response.
Funded by the U.S. Government through PEPFAR, UPHIA represents a USD 10 million investment in national evidence generation. Its results, expected in 2026, will provide updated national and subnational estimates of HIV prevalence, incidence, viral load suppression, service coverage and progress toward UNAIDS 95-95-95 targets. The survey covers 6,685 households and about 15,000 people aged 15 years and above, with additional focus on adolescents, noncommunicable diseases among people living with HIV, and barriers among those not virally suppressed.
Related surveillance work through the CRANE Survey has generated evidence on populations at higher risk of HIV and often missed by routine data. Established in 2008 with U.S. Government support through PEPFAR and implemented by MakSPH with the Ministry of Health and U.S. CDC, CRANE is one of Uganda’s longest-running HIV bio-behavioural surveillance platforms. More than USD 7 million in U.S. Government investment has supported evidence used in Uganda’s HIV Investment Case, the National HIV Strategic Plan, national bio-behavioural surveillance guidelines and UNAIDS guidance.
In its third round, conducted in 2023 and disseminated in 2024, CRANE reached 7,947 female sex workers and sexually exploited minors across 12 districts. About one in three participants were living with HIV, rising to 54 per cent among those aged 35 to 49. The survey also documented syphilis, high-risk HPV infection, violence, stigma in health facilities and high levels of depression, strengthening the case for targeted HIV prevention, treatment, mental health support, violence prevention, cervical cancer prevention and access to justice.
Then U.S. Ambassador to Uganda H.E. William W. Popp tours MakSPH exhibition stands with MakSPH and U.S. CDC leadership during the 2024 dissemination of CRANE Survey results in Kampala.
Regional Leadership, One Health and Innovation
U.S. Government support extended MakSPH’s contribution from national workforce development to regional public health leadership. In 2005, USAID, through the Higher Education for Development programme, supported the Leadership Initiative for Public Health in East Africa (LIPHEA), led by MakSPH with Muhimbili University of Health and Allied Sciences, Johns Hopkins Bloomberg School of Public Health and Tulane University School of Public Health and Tropical Medicine. The initiative strengthened leadership, competency-based training, faculty development and collaborative research across East Africa.
LIPHEA’s legacy continued through the East Africa HEALTH Alliance, which evolved into the One Health Central and Eastern Africa network and later the Africa One Health University Network (AFROHUN). These platforms brought public health, veterinary, environmental and allied disciplines into shared training and practice, helping build a workforce able to predict, detect and respond to zoonotic diseases, epidemics and other complex health threats.
The regional focus expanded further in 2012, when USAID selected Makerere University, through MakSPH, to lead the ResilientAfrica Network (RAN) under the Higher Education Solutions Network (HESN). Operating in 16 African countries through a network of 20 African universities, RAN connected African universities, U.S. partners and local innovators to strengthen community resilience to disease outbreaks, climate shocks, food insecurity, conflict and natural disasters. Through research, innovation grants, policy engagement and capacity building, it expanded MakSPH’s regional contribution to resilience science, innovation and implementation research.
METS and National Stewardship
MakSPH Dean Prof. Rhoda Wanyenze signs the METS handover board during the transition of digital health systems and assets to the Ministry of Health on 31 March 2026, as then U.S. Ambassador to Uganda H.E. William W. Popp and Dr. Diana Atwine, Permanent Secretary, Ministry of Health, look on.
A recent marker of partnership maturity came through the Monitoring and Evaluation Technical Support (METS) Programme. Launched in 2010 with U.S. Government support through the U.S. CDC and PEPFAR, METS strengthened Uganda’s health information systems, case-based surveillance, monitoring, evaluation and quality improvement for HIV, TB and broader public health programming. Across three five-year grants totalling USD 103.8 million, the programme helped move Uganda from fragmented reporting toward stronger national data systems and more integrated digital health infrastructure.
During its March 2026 handover to the Ministry of Health, METS transferred 16 digital health systems, 725 servers, more than 4,700 computing devices, solar systems for nearly 800 facilities, connectivity equipment for more than 1,300 sites, and network upgrades for regional referral hospitals. The transferred ICT infrastructure was valued at USD 9.3 million. METS also helped improve District Health Information System 2 reporting from 58 per cent in 2020 to 98 per cent by 2025, while Electronic Medical Record coverage expanded to more than 86 per cent nationally, with 1,900 sites using electronic medical records.
Infrastructure and Future Capacity
MakSPH’s new home takes shape near the Eastern Gate at Makerere University Main Campus, supported in part through the USAID ASHA grant.
MakSPH’s expanding mandate has placed new demands on its infrastructure. With more than 1,000 students, wider regional work and a growing research portfolio, the new MakSPH complex on Makerere University Main Campus is designed to support training, research, policy engagement and innovation at scale. In 2021, USAID, through the American Schools and Hospitals Abroad (ASHA) programme, awarded USD 1.1 million through Johns Hopkins University to support the Makerere University Centre of Excellence for Global Health within the new building.
The infrastructure agenda also points to the next phase of the MakSPH and U.S. Government partnership. After more than three decades of investment in leadership, evidence, surveillance, digital systems, regional networks and response capacity, sustaining these gains will require stronger shared responsibility.
As the United States marks 250 years of independence, MakSPH recognises a partnership that has strengthened Uganda’s public health system and continues to build capacity for the region.
The Infectious Diseases Institute (IDI) at Makerere University has been awarded a grant from the European and Developing Countries Clinical Trials Partnership (EDCTP) to carry out a large-scale trial of secondary TB preventive therapy. The Recurrent TB Screening and Prevention Study (RECENT TB study) is a randomized controlled trial which will be carried out in Uganda and South Africa from September 1, 2026, to August 31, 2030. The study will examine the effectiveness of secondary TPT for preventing recurrent TB while also evaluating the implementation considerations for the successful implementation of secondary TPT in public health settings and the potential of biomarkers to identify patients at the highest risk of recurrence.
To support the successful implementation of this trial, IDI is seeking a highly motivated individual to serve as a study coordinator while simultaneously pursuing a PhD. This dual role offers a unique opportunity to contribute to cutting-edge clinical research while developing advanced research skills at the doctoral level.
Job Purpose:
The Project Coordinator will be responsible for the day-to-day coordination of the trial. S/he will work closely with the Scientific Lead and the broader study team to ensure high-quality, protocol-compliant study implementation. Concurrently, s/he will be enrolled in a doctoral program, using the trial data and research experience to develop and complete a PhD thesis within the contract period.
Key Responsibilities
Study Coordination and Trial Management
Oversee participant recruitment, randomization, and follow-up schedules in accordance with the approved protocol, Good Clinical Practice (GCP) guidelines, and EDCTP regulations
Ensure timely and accurate collection, entry, and verification of study data using electronic data capture systems.
Oversee training and coordination of study nurses, health facility staff, and community health workers in both Uganda and South Africa to ensure smooth trial operations. Occasional travel to South Africa may be needed for this.
Maintain up-to-date versions of all study documentation, including study protocol, informed consent forms, and data collection tools.
Assist in the preparation of study reports, safety reports, and interim analyses for the Data Safety Monitoring Board (DSMB) and EDCTP.
Liaise with the IDI Research and Ethics Committee and the Uganda National Council for Science and Technology (UNCST) to ensure ongoing compliance.
Coordinate and support monitoring visits, audits, and inspections by the IDI monitoring unit, EDCTP, and other regulatory authorities.
Participate in study team meetings, investigator meetings, and relevant scientific conferences.
PhD Research Activities
Develop a PhD concept and enroll in an approved PhD program at Makerere University and/or the University of Amsterdam by the end of Year 1.
Develop a full doctoral research proposal in consultation with the RECENT TB Scientific and Capacity Building Leads as well as academic supervisors and achieve full registration by the end of Year 2.
Prepare and submit at least 2 manuscripts for peer-reviewed publication in accordance with PhD requirements by the end of Year 4.
Present research findings at national and international scientific conferences.
Engage with the PhD supervisory committee and attend required academic modules and seminars.
Supervise at least one master’s-level student by the end of Year 4.
Submission of PhD thesis for final viva voce examination by the end of Year 4
Reporting and Supervision
For trial-related outputs, the study coordinator will report directly to the scientific lead—RECENT TB. Regular performance reviews will be conducted by the Scientific Lead in alignment with IDI’s performance management framework. For academic purposes, s/he will report to the RECENT TB Capacity Building Lead as well as her designated PhD supervisory committee in accordance with the requirements of Makerere University and/or the Graduate School of the Amsterdam University Medical Center.
Academic Qualifications
Bachelor’s degree in medicine and surgery (MBChB), plus a Master’s degree in Public Health, Epidemiology, Clinical Research or Internal Medicine
Minimum of 5 years of experience working in clinical research or public health in the Ugandan setting, preferably in TB, HIV, or other infectious diseases.
Demonstrable interest in research, scientific writing and publication with at least one first author peer reviewed publication
Person Specification
Experience with electronic data capture tools and statistical software (RedCap, STATA, R)
Training in Human Subjects Research (HSP) and Good Clinical Practice (GCP)
Strong interpersonal skills and cultural sensitivity for working with TB affected communities.
More Details
Job Code: PJC001 No of Positions: 1 Station: IDI Mulago Classification: Full-time Duration: 9 Months Reports to: co-investigator Posted Date: 2026-07-01 10:45:53.000 Closing Date: 2026-07-14 17:00:00.000
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